From fa3f4fbfbf26c81433b7945f5652678d91bbcd0b Mon Sep 17 00:00:00 2001 From: Soothspider Date: Sun, 28 Jan 2024 16:20:36 -0800 Subject: [PATCH] AI Captions - Jan. 28 - GOF --- ...Resistance Low Noise Information Brief.vtt | 4184 +++++++++++++++++ .../README.md | 5 + 2 files changed, 4189 insertions(+) create mode 100755 twitch/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief.vtt create mode 100644 twitch/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief/README.md diff --git a/twitch/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief.vtt b/twitch/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief.vtt new file mode 100755 index 0000000..67e9f06 --- /dev/null +++ b/twitch/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief.vtt @@ -0,0 +1,4184 @@ +WEBVTT + +00:00.000 --> 00:10.800 +Early, what I want is high morbidity. + +00:10.800 --> 00:12.680 +I want people to complain. + +00:12.680 --> 00:13.760 +So what do I do? + +00:13.760 --> 00:15.280 +I go to Des Moines. + +00:15.280 --> 00:17.600 +Ladies and gentlemen and people on the screen, I have nothing against Des Moines, I live + +00:17.600 --> 00:18.600 +there for four years. + +00:18.600 --> 00:22.800 +I go to Des Moines, I infect a couple of sentinel cases in Des Moines. + +00:22.800 --> 00:26.400 +I go to Seattle, I infect a couple of cases there. + +00:26.400 --> 00:30.360 +I go to North Carolina, I go to Wisconsin. + +00:30.360 --> 00:35.040 +What I'm doing is I'm using a dispersion methodology to be able to infect sentinel cases with a + +00:35.040 --> 00:37.560 +highly morbid condition. + +00:37.560 --> 00:38.560 +These individuals complain. + +00:38.560 --> 00:42.320 +Again, this is a central nervous system condition, so they're complaining of whatever the bug + +00:42.320 --> 00:43.320 +may do. + +00:43.320 --> 00:49.000 +It'll produce some cascade of neurological and neuropsychiatric signs and symptoms. + +00:49.000 --> 00:53.480 +And then what I do, the real bug that I use is the internet. + +00:53.480 --> 00:54.880 +I take attribution for that. + +00:54.960 --> 00:56.920 +Yes, I'm a terrorist group. + +00:56.920 --> 01:00.840 +And I have done this by infecting with a highly little agent and the first signs and symptoms + +01:00.840 --> 01:03.640 +of lethality are X, Y, and Z. + +01:03.640 --> 01:05.600 +These people are really sick with this. + +01:05.600 --> 01:12.240 +But then I say, others who are also infected will show subdramal, predramal signs of lethality + +01:12.240 --> 01:17.880 +and what that will be is anxiety, sleeplessness, agitation. + +01:17.880 --> 01:22.480 +What I've now done is I've got every individual who is diagnostically hypochondriacal and I've + +01:22.520 --> 01:26.360 +got every individual who's worried well, flooding the public health system, banging + +01:26.360 --> 01:27.600 +on the door. + +01:27.600 --> 01:31.560 +The CDC comes back and says, nonsense, that's not real. + +01:31.560 --> 01:35.160 +I come back and say, that's fake news. + +01:35.160 --> 01:39.320 +And as a consequence of doing that, what I do is I create a schism between the polis + +01:39.320 --> 01:41.200 +and the public health system. + +01:41.280 --> 01:47.080 +I fracture the integrity of trust and reliance upon the population and its government. + +02:03.800 --> 02:06.800 +January 28, 2024. + +02:06.800 --> 02:08.600 +Welcome to Giga Own Biological. + +02:11.200 --> 02:13.200 +Glad all of you can join me. + +02:13.200 --> 02:19.360 +I'm trying to do a little early one and then maybe I can also do one later with a little + +02:19.360 --> 02:20.360 +more meat on it. + +02:20.360 --> 02:21.360 +I don't know. + +02:21.360 --> 02:23.360 +This one might be already a couple hours. + +02:23.360 --> 02:24.360 +We'll see what we do. + +02:24.360 --> 02:29.200 +I've got a basketball game this afternoon, I need to attend, and so I'll let you know + +02:29.200 --> 02:30.200 +what's up. + +02:30.200 --> 02:35.200 +We might have to stop this one a little early, but I think we're going to be able to make + +02:35.200 --> 02:36.200 +a good point here. + +02:36.200 --> 02:44.840 +I'm afraid that the latest data tells us that we're dealing with essentially a worse case + +02:44.840 --> 02:45.840 +scenario. + +02:45.840 --> 02:49.440 +I'm afraid that the latest data tells us that we're dealing with essentially a worse case + +02:49.440 --> 02:50.440 +scenario. + +03:06.200 --> 03:23.920 +The schedule for 16 minutes next is going on French, British, Italian, Japanese television. + +03:23.920 --> 03:27.120 +People everywhere are starting to listen to him. + +03:27.120 --> 03:28.120 +It's embarrassing. + +03:28.120 --> 03:38.400 +The rules, protect yourself at all times, follow my instructions, keep it clean, touch + +03:38.400 --> 03:41.400 +gloves if you wish, let's do it. + +03:41.400 --> 03:42.400 +20 pounds. + +03:42.400 --> 03:43.400 +This is so crazy. + +03:43.400 --> 03:44.400 +Like these bumps. + +03:44.400 --> 03:45.400 +This is so crazy. + +03:45.400 --> 03:46.400 +I feel so nervous. + +03:46.400 --> 03:47.400 +Like what in the world, man? + +03:47.400 --> 03:54.400 +We have been challenged lately in the public square that is Twitter X, to be able to see + +04:17.400 --> 04:24.040 +you try and more formalize our challenge to virology and I think we would be wise to + +04:24.040 --> 04:29.400 +move forward with caution because lots of people have tread this water before and so + +04:29.400 --> 04:31.400 +I'm pretty excited. + +04:31.400 --> 04:32.400 +Wow. + +04:32.400 --> 04:44.200 +Somebody lost a 42 year old friend to a brain and you're just, well, there's a downer. + +04:44.200 --> 04:52.080 +I'm not really sure what to say about that other than we're going to keep this fight + +04:52.080 --> 04:57.440 +up for everybody who's lost a friend and obviously it's still happening. + +04:57.440 --> 05:01.440 +I'm afraid Colin, I'm afraid it's going to get worse, not better. + +05:01.440 --> 05:04.080 +That's the issue here. + +05:04.080 --> 05:13.280 +That's the issue I feel is that that's where we are. + +05:13.280 --> 05:20.160 +They have manipulated us and we need to be the people that can hold the light to the + +05:20.160 --> 05:21.640 +truth. + +05:21.640 --> 05:22.640 +It's about the history. + +05:22.640 --> 05:24.480 +It's also about what's happening right now. + +05:24.480 --> 05:30.360 +It's about our recent history and our deep history and about things that some people just + +05:30.360 --> 05:37.200 +will not, will refuse to see. + +05:37.200 --> 05:44.240 +It's all about their God, AI and solving humanity's futuristic problems and they feel + +05:44.240 --> 05:46.240 +like they only have one chance in history. + +05:46.240 --> 05:48.120 +They've been bamboozled by themselves. + +05:48.120 --> 05:57.680 +They've been, they're bamboozling each other about this stuff. + +05:57.680 --> 06:02.000 +I got, I got called out on Twitter the other day because I don't call anybody out in big + +06:02.000 --> 06:03.000 +pharma. + +06:03.000 --> 06:05.840 +I don't call anybody out in the who or anywhere else. + +06:05.840 --> 06:14.480 +My goodness, the kind of thing that passes for debate on that platform is absolutely + +06:14.480 --> 06:15.480 +laughable. + +06:15.480 --> 06:20.040 +If you can't see the brick wall right now, I think we're in big trouble. + +06:20.040 --> 06:26.440 +Hopefully everybody here can see the brick wall of course, but that's 46 of you, 47 counting + +06:26.440 --> 06:27.440 +me. + +06:27.440 --> 06:35.680 +That's not a lot and we need to share this just a little bit more if you don't mind. + +06:35.680 --> 06:52.960 +This is a stream brought to you by a patch clamp physiologist. + +06:52.960 --> 06:59.520 +GigaOM is a resistance measurement, a value of resistance that you want to achieve when + +06:59.520 --> 07:04.920 +you're making these recordings and so I named this stream GigaOM biological and you can + +07:04.920 --> 07:11.280 +find that at dot com, you can also find us at GigaOM dot bio, which is a area placed + +07:11.280 --> 07:12.280 +in chat. + +07:12.280 --> 07:17.320 +You can support me with one time donation at the support GigaOM and then there's also + +07:17.320 --> 07:24.800 +a way to subscribe and I would really strongly encourage anybody who's been sitting on their + +07:24.800 --> 07:29.840 +hands about this to get on board right now because this, we've got about two months to + +07:29.840 --> 07:35.720 +see if we can push this boat out or if we're going to have to make some drastic changes + +07:35.720 --> 07:37.800 +to how we move forward. + +07:37.800 --> 07:46.040 +Right now the people that are helping us, helping my family try to push this boat out + +07:46.040 --> 07:49.000 +are listed here and it's not the only people. + +07:49.000 --> 07:52.080 +There's also some people who've made some single donations that I haven't been able + +07:52.080 --> 07:57.280 +to get onto the board yet and so you've got to apologize to me or I got to apologize + +07:57.280 --> 07:59.880 +to you for that. + +07:59.880 --> 08:05.720 +My wife and I, my wife has started to actually work for GigaOM biological in that respect + +08:05.720 --> 08:20.520 +and so communication should get a little better and so hopefully that's the case. + +08:20.520 --> 08:22.520 +So where are we? + +08:22.520 --> 08:27.840 +We are pushing back pretty hard now against the traditional idea of a pandemic, the idea + +08:27.840 --> 08:33.600 +that either a laboratory leak or a bat cave virus started somewhere in late 2019 and then + +08:33.600 --> 08:38.240 +circulated around the globe with pretty high fidelity, changing color as it went and that + +08:38.240 --> 08:39.480 +we're in the fifth year of it. + +08:39.480 --> 08:45.720 +We're pushing very hard against this faith in a novel virus but we can't stop now. + +08:45.720 --> 08:47.080 +We've got to clean up the mess. + +08:47.080 --> 08:53.640 +We've got to clean up the recent history mess before it becomes a lie that becomes + +08:53.640 --> 08:57.400 +the truth because they don't understand that it could have been a background signal, they + +08:57.400 --> 09:00.360 +don't understand that it could have been clones, they don't understand that it could have been + +09:00.360 --> 09:04.360 +a combination of many of these things. + +09:04.360 --> 09:11.680 +And I think it's really important that these ideas are always at the front because they're + +09:11.680 --> 09:15.280 +going to try and make it seem like, you know, the details of the story. + +09:15.280 --> 09:20.400 +Taking home gets all the details wrong, he doesn't know all the details. + +09:20.400 --> 09:24.000 +While they ignore the big messages and the big messages are the ones that we need to + +09:24.000 --> 09:29.800 +get to our kids, the big messages about this being an illusion, about this being a mythology + +09:29.800 --> 09:36.200 +that all of these people have somehow or another collectively agreed not to challenge and that + +09:36.200 --> 09:40.320 +they don't talk about there being no spread in New York City infectious clones, placebo + +09:40.320 --> 09:44.840 +batches or transfection, they don't talk about the protocols or gain a function being + +09:44.840 --> 09:49.400 +a mythology and they don't talk about us being fooled in dissolving this mystery because + +09:49.400 --> 09:56.680 +they are committed to this and they have a spectacular commitment to this lie. + +09:56.680 --> 10:01.040 +That's what I'm talking about, congratulations on Substack, thank you very much. + +10:01.040 --> 10:08.720 +It's taken me a little while to get that rolling and now I figured it out in Premiere and so + +10:08.720 --> 10:16.000 +making the transcript and the subtitles is not a ridiculous task anymore and so that's + +10:16.000 --> 10:17.560 +pretty fun. + +10:17.560 --> 10:24.640 +I'm really, really happy about that so thanks very much for noticing that I got that rolling. + +10:24.640 --> 10:28.960 +Hold on a second, let me get over here. + +10:28.960 --> 10:34.240 +Thank you very much for joining me, it is 2.40 in the afternoon here in Pittsburgh, Pennsylvania, + +10:34.240 --> 10:35.240 +USA. + +10:35.240 --> 10:40.160 +I'm coming to you from the back of my garage, this is Gigoland Biological, hey, high resistance + +10:40.160 --> 10:42.560 +low noise information brief brought to you by a biologist. + +10:42.560 --> 10:49.280 +My name is Jonathan Cooey and as I said, it's the 28th of January and I don't know, I guess + +10:49.280 --> 10:55.840 +you can steal my identity now that you know that this is my birthday and I'm 52 but anyway, + +10:55.840 --> 11:02.800 +this is your 52 year old biologist who's put four hard years of his life into this, it's + +11:02.800 --> 11:04.800 +pretty crazy. + +11:04.800 --> 11:10.240 +I have a little plan here and I want to stick to it, oh, there's the secret, I didn't want + +11:10.240 --> 11:16.920 +that to show up yet, anyway, we will save that, that's fine. + +11:16.920 --> 11:19.720 +And then I'm going to pull up a new slide deck, it's a quick one and then we're going + +11:19.720 --> 11:24.920 +to get right to this movie which is actually session five of a gain of function research + +11:24.920 --> 11:31.480 +meeting from 2016 and I just wanted to do a brief introduction to it to make sure that + +11:31.480 --> 11:34.720 +we're all on the same page, especially of those of you who might be lucky enough to + +11:34.720 --> 11:37.640 +join us for the first time. + +11:37.640 --> 11:43.040 +We are trying to do the honorable thing and tell the truth to the young. + +11:43.040 --> 11:49.720 +In so doing, we need to dispel this idea which was first most adequately summarized by Edward + +11:49.720 --> 11:54.480 +Bernays in the early 20th century that the conscious and intelligent manipulation of + +11:54.480 --> 12:00.640 +the organized habits and opinions of the masses is an important element of democratic society. + +12:00.640 --> 12:03.840 +And now I want you to think about the fact that this guy came up with this idea in the + +12:03.840 --> 12:12.720 +20s when there were just newspapers and town criers and bulletins and things like that. + +12:12.720 --> 12:19.040 +And maybe soon after radio and telegram, but now we're talking about social media and think + +12:19.040 --> 12:24.480 +about what this statement means in the context of social media, in the context of algorithms + +12:24.480 --> 12:32.400 +in the context of amplification and whatever they call it, throttling or think about all + +12:32.400 --> 12:40.720 +of these things which are definitely real, definitely at play so that we get a very distorted + +12:40.720 --> 12:41.960 +view of the world. + +12:41.960 --> 12:48.960 +If we look through this particular window, we're going to have a very distorted view of + +12:48.960 --> 12:51.960 +the world and yet most of us are looking through that window. + +12:51.960 --> 12:57.580 +Some of us are looking at me through that window right now. + +12:57.580 --> 13:07.320 +And so in effect, right, in effect, the principal of informed consent has been ignored for the + +13:07.320 --> 13:11.440 +duration of the pandemic because we've been, you know, scrolling up and down and following + +13:11.440 --> 13:15.840 +all these people on Twitter and trying to figure out the truth by getting involved in + +13:15.840 --> 13:20.560 +different DM groups on Twitter and different signal chats and different telegram groups + +13:20.560 --> 13:25.760 +and different GAB and following locals videos that no one else pays to watch so you have + +13:25.760 --> 13:27.200 +the inside story. + +13:27.200 --> 13:35.760 +This is all the same surrendering basically of your informed consent just by overwhelming, + +13:35.760 --> 13:39.120 +overwhelming you, overwhelming your family and then isolating you as well. + +13:39.120 --> 13:47.560 +Look at that little girl on the couch. + +13:47.560 --> 13:54.440 +And so I firmly believe that this is the best American version of the deception that + +13:54.440 --> 13:55.440 +occurred. + +13:55.440 --> 13:59.880 +I'm sure it occurred everywhere around the world that they tricked the average TV watching + +13:59.880 --> 14:07.600 +social media surfing person to think that they were witnessing a sort of bad coverup + +14:07.600 --> 14:13.280 +of what turns out to be with a result of whistleblowers and leaks. + +14:13.280 --> 14:18.160 +More or less, a US funded gain of function program in Wuhan that ended up causing this + +14:18.160 --> 14:22.400 +calamity and we have been led to believe that we solved this problem. + +14:22.400 --> 14:27.520 +And I've given you this list of things to help you think about how the pandemic was + +14:27.520 --> 14:32.320 +created, which starts with seeding the gain of function narrative with scientific programs + +14:32.320 --> 14:36.520 +and peer reviewed publications for years before the pandemic. + +14:36.520 --> 14:42.160 +And then also remember that there were regular upper level exercises in the government, international + +14:42.240 --> 14:48.840 +exercises in the government, which drilled these, the response to such a pandemic potential + +14:48.840 --> 14:51.960 +actually emerging. + +14:51.960 --> 14:58.760 +And then we seeded mass casualty events with expected outcomes of transfection, at least + +14:58.760 --> 15:02.960 +let's just say that we didn't do anything to stop that. + +15:02.960 --> 15:08.440 +And more importantly, what we did was we had a bunch of actors in all different levels + +15:08.440 --> 15:15.000 +of social media and on mainstream media that we're prepared to, that were set up to were + +15:15.000 --> 15:23.760 +directed to, were encouraged to seed the narrative of the gain of function, the lab leak and + +15:23.760 --> 15:28.640 +attributes of the infection, the bad parts of the attributes that go all the way from + +15:28.640 --> 15:34.040 +heart attacks and myocarditis all the way up to amyloidosis and prion disease as a + +15:34.040 --> 15:42.440 +way of putting forth ideas which could then be confounded at the time when some of these + +15:42.440 --> 15:47.040 +symptomologies would emerge as a result of the transfection. + +15:47.040 --> 15:53.160 +And I believe that these people knew that some of these expected outcomes of mass transfecting + +15:53.160 --> 16:00.200 +the population could have been known and then could have been purposefully seeded into the + +16:00.240 --> 16:07.000 +virus narrative early on as the worst case scenario was being pushed behind the scenes + +16:07.000 --> 16:10.920 +and and off camera. + +16:10.920 --> 16:15.320 +And you could have participants that were involved in this, that were involved in a national + +16:15.320 --> 16:22.680 +security priority response, even like people at news, like producers at news programs, + +16:22.680 --> 16:29.120 +for example, could be could have been briefed secretly to say, Hey, you know, we have to + +16:29.120 --> 16:35.480 +talk these talking points and the entire news program and the entire all the newscasters + +16:35.480 --> 16:39.880 +would be clueless as to why their lines were the way that they were there. + +16:39.880 --> 16:44.720 +It's not a whole, you know, the whole channel 11 is not in on it. + +16:44.720 --> 16:49.720 +It only has to be one person at the top or near the top for this to have been flawlessly + +16:49.720 --> 16:54.800 +executed at every level of media. + +16:54.800 --> 16:58.800 +And so in the end, we have this virus and this transfection and it's their effects + +16:58.800 --> 17:03.480 +confounded and so that we're still arguing about whether it and they added to it. + +17:03.480 --> 17:08.920 +Of course, they've added this, this contamination and I believe they added this contamination + +17:08.920 --> 17:13.200 +because the spike protein toxicity narrative didn't take hold. + +17:13.200 --> 17:15.440 +It wasn't powerful enough. + +17:15.440 --> 17:23.840 +Maybe the dissident movement didn't bite it as hard as they wanted them to bite it. + +17:23.840 --> 17:28.040 +And so I have been putting up pictures of all kinds of people that I follow on Twitter + +17:28.040 --> 17:32.800 +and making the argument that it's the spread of these worst case scenario bad ideas that + +17:32.800 --> 17:37.400 +allowed this narrative to tumble forward out of control and allowed them to steer it right + +17:37.400 --> 17:40.120 +toward the need for transfection. + +17:40.120 --> 17:41.760 +And so a lot of people were just on board. + +17:41.760 --> 17:43.280 +They're just unwitting. + +17:43.280 --> 17:45.800 +They didn't know. + +17:45.800 --> 17:48.320 +And so we've talked about these guys before. + +17:48.320 --> 17:52.800 +We've talked about these guys before, you know, these guys are the ones who are arguing + +17:52.800 --> 17:53.800 +now. + +17:53.800 --> 18:00.000 +I've talked, I've found something very interesting with regard to Sasha Latipova. + +18:00.000 --> 18:03.920 +I've always wondered, I've been wondering about her, I've had her on my stream before + +18:03.920 --> 18:09.800 +with regard to the, to the shots and their, and their different batches. + +18:09.800 --> 18:15.080 +And then since then, she was on stage with Robert Malone and, and Meryl Nast and it's + +18:15.080 --> 18:17.640 +just been kind of a hands off situation at this stage. + +18:17.640 --> 18:22.320 +I don't need, I don't think a lot of us need to cooperate and have phone calls and, + +18:22.320 --> 18:26.600 +and, and have secret meetings all the time if we are all fighting the same thing that + +18:26.600 --> 18:27.600 +it's going to be fine. + +18:27.600 --> 18:30.240 +And I think what I see here is evidence of that. + +18:30.240 --> 18:33.040 +Now, I don't know, but it sure seems kind of cool. + +18:33.040 --> 18:39.320 +I didn't notice it until now, but this is January 17th, 2024, how to fake pandemics + +18:39.320 --> 18:44.760 +in four easy steps, due diligence and art is Sasha Latipova's sub stack. + +18:44.760 --> 18:50.000 +And here she said, she gives a shout out to, to, uh, John Bodwin, who I consider to + +18:50.000 --> 18:54.760 +be a really hard working guy who's got a great signal with regard to where the mortality + +18:54.760 --> 18:57.120 +came from and didn't come from during the entire pandemic. + +18:57.120 --> 19:01.840 +And he's got a lot of good information about the fact that the protocols were likely murder. + +19:01.840 --> 19:02.840 +And I love that. + +19:02.840 --> 19:04.440 +And I love John's work. + +19:04.440 --> 19:09.600 +And so her, um, saying that that's the case is, uh, is also really cool. + +19:09.600 --> 19:13.120 +Then down here, she's saying that the Spanish flu is also a fake pandemic. + +19:13.120 --> 19:17.080 +So that's something that I know my friend, Mark Koolak would agree with wholeheartedly. + +19:17.080 --> 19:25.400 +So I mean, two, two, whoops, so so far, she's digging all the bells. + +19:25.400 --> 19:27.040 +I mean, this is great. + +19:27.040 --> 19:31.120 +Pandemics are also not possible via science in what is called gain of function research, + +19:31.120 --> 19:36.520 +which amounts to mostly ridiculous attempts at software enabled sorcery, making soups + +19:36.520 --> 19:40.440 +of chemical mix with literally shit. + +19:40.440 --> 19:44.320 +As I discussed you in my previous article, yes, toxic chemicals and shit cause poisoning, + +19:44.320 --> 19:46.040 +but this does not spread itself. + +19:46.040 --> 19:49.760 +Of course, these labs should be shut down a waste of money and hazard thanks to Merrill + +19:49.760 --> 19:55.560 +Nass for this new, um, bulletin of atomic scientists where they talk about lab leaks + +19:55.560 --> 19:56.560 +and stuff like that. + +19:56.560 --> 19:58.120 +So here we go again. + +19:58.120 --> 20:02.680 +One way to look at this is that, that lab leaks mean that we're in trouble and there's + +20:02.680 --> 20:07.800 +going to be another, uh, pandemic or another way to look at it is is that the background + +20:07.800 --> 20:10.120 +is much richer. + +20:10.120 --> 20:15.760 +The background is much hotter in terms of PCR and in terms of coronavirus sequences and + +20:15.760 --> 20:20.760 +coronavirus diversity than any of these people want to admit, especially because our actual + +20:20.760 --> 20:26.320 +surveillance of the nine billion people on the planet is ridiculously low and has always + +20:26.320 --> 20:31.920 +been except for these last two or three years from 2020 onward. + +20:31.920 --> 20:32.920 +And so this is cool. + +20:32.920 --> 20:38.600 +This is a shout out to Merrill Nass, Merrill Nass being, um, a woman who has her own new + +20:38.600 --> 20:41.920 +nonprofit called doors to freedom or something like that. + +20:41.920 --> 20:48.200 +And also was a longtime advisor to CHD, uh, an organization that you and I both know + +20:48.200 --> 20:50.440 +that I really, really admire. + +20:50.440 --> 20:56.600 +So this is still, I mean, now we're on page two and we're, we're still just, you know, + +20:56.600 --> 21:00.360 +so hey, I mean, work hard, die rich, I guess is working out for her. + +21:00.360 --> 21:04.400 +And all pandemics to date have been faked by the military industrial globalist cabal, + +21:04.400 --> 21:09.760 +which sounds kind of like what we've come to the conclusion of over the last year or + +21:09.760 --> 21:10.760 +so. + +21:10.760 --> 21:17.680 +Um, sorry, JFK, RFK, despite your desire to appear middle ground, um, by including a + +21:17.680 --> 21:23.400 +lie with a majorly true majority truthful statement, COVID pandemic was also faked using + +21:23.400 --> 21:25.640 +the same basic script actors and funding. + +21:25.640 --> 21:26.640 +So that's interesting. + +21:26.640 --> 21:27.640 +I wonder what that video is. + +21:27.640 --> 21:28.880 +I won't play that now. + +21:28.880 --> 21:34.200 +But again, here she is kind of criticizing, uh, Bobby Kennedy for not going far enough, + +21:34.200 --> 21:41.000 +um, to say that the pandemic is fake, which is very, very interesting because again, remember, + +21:41.000 --> 21:48.040 +if they used enough clones, then from a molecular biological perspective, the pandemic doesn't + +21:48.040 --> 21:51.800 +need to be faked. + +21:51.800 --> 21:56.640 +And I think what we're dealing with here now is just realizing that there is a way to apply + +21:56.640 --> 22:02.280 +these techniques with the proper investment, the proper, the proper, whatever. + +22:02.280 --> 22:06.920 +I mean, you can call it Keystone cop if you want to, but moving viruses around is quite + +22:06.920 --> 22:12.120 +a bit easier than moving WMDs or, or missiles or things like that. + +22:12.120 --> 22:16.360 +I mean, we're talking about very small quantities being able to do in theory, very big things, + +22:16.360 --> 22:23.640 +especially if the only thing you want to do is have a PCR or a sequencing signal. + +22:23.640 --> 22:25.960 +Because the DNA could be put on people's clothes. + +22:25.960 --> 22:27.920 +It could be contaminated on swabs. + +22:27.920 --> 22:30.000 +It could be put purposefully in tests. + +22:30.000 --> 22:34.760 +There are a million ways to make enough DNA for this signal to go all around the world + +22:34.760 --> 22:39.480 +for sure, not by itself. + +22:39.480 --> 22:41.440 +And that's the point. + +22:41.440 --> 22:42.680 +That's the argument we're making. + +22:42.680 --> 22:43.680 +So this is okay. + +22:43.680 --> 22:45.320 +I mean, that's not bad. + +22:45.320 --> 22:48.640 +And then whoa, hey, look, what is the pandemic script? + +22:48.640 --> 22:49.960 +Let's hear it from the horse's mouth. + +22:49.960 --> 22:57.120 +And she shows James Giordano and the actual video that I've been using for almost three + +22:57.120 --> 22:58.960 +years now. + +22:58.960 --> 23:04.600 +It's hard to believe that she didn't see it on our work. + +23:04.600 --> 23:10.320 +And it's, you know, okay, I don't care because these ideas are getting out. + +23:10.320 --> 23:18.600 +If she never attributes this to me, but more people through her sub stack come to realize + +23:18.600 --> 23:20.240 +that the pandemic could have been. + +23:20.240 --> 23:27.680 +And it's a really good possibility that it was almost exclusively a lie, a coordinated + +23:27.680 --> 23:31.240 +spectacular commitment to lies. + +23:31.240 --> 23:35.880 +And that lie being the worst case scenario, then this is great. + +23:35.880 --> 23:46.000 +You have to see if this is worst case scenario, this is imitation, which is flattery, right? + +23:46.000 --> 23:50.840 +This case scenario, it's just, I guess, great minds think alike or something like that. + +23:50.840 --> 23:51.840 +But this is good. + +23:51.840 --> 23:52.840 +This is good. + +23:52.840 --> 23:57.200 +I consider it kind of, I don't know, I didn't see it until now, so I can call it a little + +23:57.200 --> 23:58.200 +birthday present. + +23:58.200 --> 24:04.760 +Anyway, I think the most important thing to see is that as everybody makes and fans the + +24:04.760 --> 24:11.720 +flames of hatred and frustration over Cooey being a divider or Cooey being out of his + +24:11.720 --> 24:16.920 +lane or whatever Cooey is doing six hour Scooby-Doo's instead of doing sequence searches + +24:16.920 --> 24:23.180 +on NCBI, we don't talk about these messages, which I think are the most important ones. + +24:23.180 --> 24:29.480 +If we can pass on to our children the immunology and general biology and appreciation for the + +24:29.480 --> 24:34.840 +sacred to understand that intramuscular injection of any combination of substances with the intent + +24:34.840 --> 24:40.000 +of augmenting the immune system is dumb, then our children and more importantly, our grandchildren + +24:40.000 --> 24:42.360 +will be fine. + +24:42.360 --> 24:46.920 +If we can teach our college age kids the transfection and healthy humans should be considered + +24:46.920 --> 24:53.400 +criminally negligent, we can turn those college age kids on their college faculty. + +24:53.400 --> 24:57.120 +Because it is their college faculty and I would go so far as to say specifically their + +24:57.120 --> 25:03.040 +natural sciences faculty, their chemistry faculty, their biochemistry faculty, their + +25:03.040 --> 25:09.200 +biology faculty, their medical school faculties, they should all be turned on. + +25:09.200 --> 25:14.160 +They should not necessarily be forced to kneel in the hallway or something like that, + +25:14.160 --> 25:18.760 +but every one of them should be forced to collectively admit as a faculty that they + +25:18.760 --> 25:24.720 +made a huge mistake by not stepping in front of this train. + +25:24.720 --> 25:29.000 +Everybody at the University of Pittsburgh should be sending me a card saying sorry dude + +25:29.000 --> 25:32.560 +were you right, I know they won't. + +25:32.560 --> 25:38.720 +But I'm saying that if we teach our college kids these truths, then that possibility becomes + +25:38.720 --> 25:43.400 +closer to reality, we're not going to make that happen, we can't make that happen because + +25:43.400 --> 25:49.920 +we aren't the ones this battle is about, we aren't the conscious that they're fighting + +25:49.920 --> 25:55.160 +for, they're fighting for our kids consciousness. + +25:55.160 --> 26:00.240 +And so in order to help for this, I think that I went back to that list, oh no I guess + +26:00.240 --> 26:05.620 +I didn't, I thought I did, and this is the first thing on the list, seeding the gain + +26:05.620 --> 26:09.820 +of function narrative with scientific programs and peer reviewed publications for years before + +26:09.820 --> 26:11.340 +the pandemic. + +26:11.340 --> 26:20.780 +Yesterday we watched a video from 2007, which was a bad video lecture of Ralph Barrick, + +26:20.780 --> 26:25.820 +which again I was, I'm still, I still assume it's a sketchy video because it was put up + +26:25.820 --> 26:30.820 +too late is put up by a weird account that I think is kind of associated maybe possibly + +26:30.820 --> 26:32.780 +with George Webb. + +26:32.780 --> 26:35.340 +And it had audio that was edited. + +26:35.340 --> 26:36.900 +The video was really poor. + +26:36.900 --> 26:40.340 +And so I'm not sure whether the video is just poor and then people thought you wouldn't + +26:40.340 --> 26:42.060 +be able to get anything from it. + +26:42.060 --> 26:45.660 +And they needed to edit those two parts out early because they said something crucial + +26:45.660 --> 26:48.540 +about his understanding of the infectious cycle. + +26:48.540 --> 26:50.100 +I'm not really sure. + +26:50.100 --> 26:55.460 +But I'm assuming that that video in some way or another was make meant to make us Scooby-Doo, + +26:55.460 --> 26:58.060 +remove the mask of Barrick and say, wow, it's really true. + +26:58.060 --> 27:01.660 +Now that you remind me, I forgot how incriminating these videos were. + +27:01.660 --> 27:06.740 +And I think this could be actually an instructive way to push that farther because last night + +27:06.740 --> 27:11.340 +I think our conclusion was is that Barrick had a number of ideas on how to attenuate + +27:11.340 --> 27:18.740 +viruses to make vaccines, how to prevent de-attentuation in coronaviruses was big on his radar. + +27:18.740 --> 27:25.620 +And he was looking to harness what I think he saw as a more ubiquitous signal in nature + +27:25.620 --> 27:28.740 +and use it as a biotechnology. + +27:28.740 --> 27:33.300 +And I proposed this three years ago already when I was starting to kind of understand + +27:33.300 --> 27:37.100 +what was going on with coronavirus and had listened to a lot of what he said and had + +27:37.100 --> 27:39.060 +listened to this particular symposium. + +27:39.060 --> 27:43.540 +But now I would like to revisit it because I think it's a really important symposium + +27:43.540 --> 27:52.780 +and I noticed that my friend Mark Koolack at Hewson-Tonic ITS had built a webpage around + +27:52.780 --> 27:53.780 +it. + +27:54.780 --> 28:00.180 +Here, let me clip that out and send it to you on the chat so that everybody can find + +28:00.180 --> 28:01.180 +it. + +28:01.180 --> 28:08.940 +If you're not familiar, his website and show are one of the only advertisements that + +28:08.940 --> 28:14.380 +I have in the beginning of my stream. + +28:14.380 --> 28:18.620 +And this website has all of the videos there. + +28:18.620 --> 28:20.420 +It has some of the brochures. + +28:20.420 --> 28:22.500 +That's where I got this little thing from. + +28:22.500 --> 28:23.980 +And I didn't peruse the whole thing. + +28:23.980 --> 28:25.340 +I just queued this thing up. + +28:25.340 --> 28:28.260 +So this is actually queued up on YouTube. + +28:28.260 --> 28:33.180 +It's not, I queued it up directly on YouTube, but it's also, the link is also available + +28:33.180 --> 28:34.860 +on Mark's website. + +28:34.860 --> 28:41.020 +And I can't stress enough how important it is, this work that Mark does, all this archiving + +28:41.020 --> 28:46.100 +and all of this, you know, putting everything in one place is so important in light of the + +28:46.100 --> 28:50.300 +fact that a lot of times I think some of this stuff is just not really archived on purpose. + +28:50.300 --> 28:54.220 +It's not that it's not out there, but nobody's making an extra effort to be sure that it's + +28:54.220 --> 28:55.220 +available. + +28:55.220 --> 28:59.980 +And I think Mark has done just a absolutely breathtaking job of collating some of this + +28:59.980 --> 29:06.060 +stuff together so that when you follow people through their career or you follow people + +29:06.060 --> 29:11.820 +through their education or through the development of their ideas, you can really, you know, + +29:11.820 --> 29:13.860 +link to link to link all on one site. + +29:13.860 --> 29:15.940 +I mean, it's really a master work. + +29:15.940 --> 29:16.940 +So kudos to Mark. + +29:16.940 --> 29:17.940 +Here we go. + +29:18.940 --> 29:22.460 +Um, an excellent session on the potential. + +29:22.460 --> 29:28.020 +I do have it at normal speed because they have, they're speaking a lot. + +29:28.020 --> 29:29.740 +They say a mouthful. + +29:29.740 --> 29:33.500 +So we'll see how far we can get before I have to go to the game. + +29:33.500 --> 29:34.740 +I got at least an hour. + +29:34.740 --> 29:40.220 +So let me ask the four panelists to come up now and we can so get settled in and get + +29:40.220 --> 29:50.540 +comfortable. + +29:50.540 --> 29:55.460 +There is King clone. + +29:55.460 --> 29:58.220 +And that's a dort murder, Dortmer. + +29:58.220 --> 30:03.820 +He's the guy from Norvartis that makes synthetic flu viruses for vaccines. + +30:03.820 --> 30:09.140 +And then the third guy is, um, who's that dude? + +30:09.140 --> 30:10.340 +And then this is denizen. + +30:10.340 --> 30:17.300 +This is the remdesivir guy and this is, um, the coronavirus editing guy speaking for + +30:17.300 --> 30:20.060 +for about five minutes and then we'll have a little crush discussion. + +30:20.060 --> 30:21.820 +So this is going to be kind of cool. + +30:21.820 --> 30:23.700 +These two dudes are like hardcore. + +30:23.700 --> 30:27.140 +This guy makes flu virus every year for the vaccine. + +30:27.140 --> 30:29.460 +So he's like, he knows all about clones. + +30:29.460 --> 30:30.460 +Trust me. + +30:30.460 --> 30:31.460 +I'll make this quick. + +30:31.460 --> 30:33.620 +Um, maybe the next slide, please. + +30:33.620 --> 30:38.700 +So I'm going to basically present just a little vignette on how gain of function research + +30:38.700 --> 30:47.060 +and the regulation around research affects a real world case of trying to apply some + +30:47.060 --> 30:48.060 +virology to Jeffrey. + +30:48.060 --> 30:49.060 +How are you? + +30:49.060 --> 30:50.060 +Good to see you, man. + +30:50.060 --> 30:54.180 +So just a historical reminder that I think most of you are well aware of. + +30:54.180 --> 31:01.500 +And that is that in 2009, we had the fastest vaccine response in history, but the vaccine + +31:01.500 --> 31:04.540 +came to market and substantial quantities after the disease peak. + +31:04.540 --> 31:09.780 +You can see in the brown curve, a peak occurring about October, no substantial quantity + +31:09.780 --> 31:13.260 +of vaccine was really in the market until probably getting towards December. + +31:13.260 --> 31:15.060 +So that's not what you want. + +31:15.060 --> 31:22.020 +In fact, there is an estimate from Boris et al published in EID emerging infectious diseases + +31:22.020 --> 31:27.580 +that for every week of acceleration vaccine supply in the US, and this is US centric because + +31:27.580 --> 31:33.580 +that's where the statistics are, would have been an additional 300,000 to 430,000 US cases. + +31:33.580 --> 31:37.540 +So while in research, you may think in terms of years, in terms of outbreak and pandemic + +31:37.540 --> 31:40.060 +response, you have to think in terms of days. + +31:40.060 --> 31:47.020 +And so here, I think it's important to point out that they really are talking in what I + +31:47.020 --> 31:50.300 +considered to be at least an honest broker way. + +31:50.300 --> 31:54.500 +What they're arguing is is that if they don't get the vaccine done till here and the peak + +31:54.500 --> 31:59.220 +of the epidemic is here, then they're not really saving very many people with this vaccine. + +31:59.220 --> 32:04.700 +And so ideally, we'd be able to make the vaccine back here and then avoid this peak. + +32:04.700 --> 32:09.780 +So the assumption is, is that if they had gotten this vaccine into these people that + +32:09.780 --> 32:14.140 +died or whatever, I guess number of cases per week. + +32:14.140 --> 32:19.180 +So these cases could have been prevented if they'd gotten the vaccine here earlier. + +32:19.180 --> 32:23.060 +And that's a, that's a pretty bold statement. + +32:23.060 --> 32:27.260 +But it's an easy statement to make because according to the scheme that they currently + +32:27.260 --> 32:30.220 +run, they never have the vaccine ready for the peak. + +32:30.220 --> 32:33.140 +And so there's no peak to avoid. + +32:33.140 --> 32:36.420 +And they can just say, well, yeah, look, there's no more flu anymore. + +32:36.420 --> 32:38.260 +Do you see what I'm saying? + +32:38.260 --> 32:43.820 +It's a little, it's nice to make this argument, but in making this argument, what they are + +32:43.820 --> 32:48.260 +admitting is that what they do is worthless. + +32:48.260 --> 32:51.540 +And in fact, no matter how often they do it, they're always behind. + +32:51.540 --> 32:53.020 +And so it can't really help. + +32:53.020 --> 32:56.060 +It might, it might as well leave it. + +32:56.060 --> 32:57.660 +But then you're not going to make these products. + +32:57.660 --> 32:58.660 +You're not going to make any money. + +32:58.660 --> 33:02.820 +You're not going to have this warm base of manufacturing as Robert Malone described it + +33:02.820 --> 33:06.580 +ready and waiting for when the really big one comes, which is what the argument is. + +33:06.580 --> 33:12.920 +That also Robert F Kennedy Jr. so eloquently explained on his own podcast when I was there. + +33:12.920 --> 33:17.460 +So they all have this idea that there is a worst case scenario and we do need to be + +33:17.460 --> 33:18.460 +prepared for it. + +33:18.460 --> 33:20.660 +And that's legitimate. + +33:20.660 --> 33:23.660 +Robert Malone has been saying that for many years now. + +33:23.660 --> 33:31.100 +Robert F Kennedy Jr. will say that Tony Fauci has said that David Holness said that + +33:31.100 --> 33:39.180 +Cina Bavaria said that they all say that and they all say that vaccines come too late. + +33:39.180 --> 33:42.020 +And so this is the exact same story. + +33:42.020 --> 33:51.180 +Now what I want you to make note of is that the same blog that put out the video that + +33:51.180 --> 33:56.060 +we watched last night that I said was, well, it's okay, it's a little, it's nice. + +33:56.060 --> 34:01.180 +But what it showed to me was that Berwick was really in earnest working on the biological + +34:01.180 --> 34:08.740 +potential for good that this coronavirus signal represented to him rather than working on + +34:08.740 --> 34:12.220 +gain a function dual research kind of crap. + +34:12.220 --> 34:14.340 +That wasn't even in that story. + +34:14.340 --> 34:19.660 +Now interestingly, that was from 2007 and now that will blog, the same blog that's written + +34:19.660 --> 34:26.740 +with, is his name, Leak, and then also with Dr. McCulloch has put up a more recent video + +34:26.740 --> 34:32.940 +from 2018, which we've watched before, which is Ralph Barrett giving another talk about + +34:32.940 --> 34:40.700 +chimeric coronavirus, but very, very dubiously starting with a 10 minute or 15 minute lecture + +34:40.700 --> 34:47.180 +about planet wide catastrophes and how often they occur, everything from Carrington events + +34:47.180 --> 34:50.940 +to tidal waves and super volcanoes. + +34:50.940 --> 35:00.620 +And then of course he's trying to put pandemics into that category of super cataclysmic events + +35:00.620 --> 35:11.500 +equivalent to a meteor strike or a solar windstorm, a pole reversal or a pandemic. + +35:11.500 --> 35:18.020 +So that's a pretty huge change in sales pitch from the 2007, which was, you know, + +35:18.020 --> 35:23.300 +I work on SARS viruses, SARS went around last year and we're working on trying to understand + +35:23.300 --> 35:24.300 +it. + +35:24.300 --> 35:25.300 +Here we go. + +35:25.300 --> 35:30.900 +Instead, he had this 10 or 15 minute pitch about all the worst case scenarios on the planet + +35:30.900 --> 35:39.460 +in order to frame his research has aimed precisely at one of these worst case scenario targets. + +35:39.460 --> 35:42.860 +It's extraordinary. + +35:42.860 --> 35:49.660 +And so this is 2016 and I would go so far as to say, I don't hear it here yet either. + +35:49.660 --> 35:53.100 +But that we haven't watched the whole six hours of videos or anything like that. + +35:53.100 --> 35:56.260 +So this is really about responding to a pandemic. + +35:56.260 --> 35:57.260 +So I'll let it run again. + +35:57.260 --> 35:58.260 +I apologize. + +35:58.260 --> 36:01.460 +I just thought I would point that out that that that video is also there, but I chose + +36:01.460 --> 36:07.780 +not to watch it because I'm not, I'm not convinced that that's the real Ralph Barrett. + +36:07.780 --> 36:15.580 +I'm not convinced that the real Ralph Barrett would open his talk with a 15 minute introduction + +36:15.580 --> 36:24.420 +into, you know, really, he was kind of, he was kind of speculating about some of these + +36:24.420 --> 36:25.420 +things. + +36:25.420 --> 36:30.420 +You know, he doesn't know how how devastating a meteor would be or how the geotechnics works + +36:30.420 --> 36:31.420 +after a meteor strike. + +36:31.420 --> 36:33.660 +I mean, what's he talking about? + +36:33.660 --> 36:34.660 +But he did. + +36:35.340 --> 36:38.540 +I mean, if I was a neuroscientist, I would never start with that. + +36:38.540 --> 36:42.060 +Even if I worked on pre-on disease and thought that pre-on disease could wipe out the planet + +36:42.060 --> 36:47.860 +like some people do, I wouldn't start my talk with, well, there are Carington events and + +36:47.860 --> 36:55.420 +big meteors and pole reversals and tidal waves and, and, and then my stuff, pre-ons. + +36:55.420 --> 36:57.780 +I mean, that's just crazy anyway. + +36:57.780 --> 36:58.780 +Here we go. + +36:58.780 --> 36:59.780 +Next slide. + +36:59.780 --> 37:06.580 +All in response to that in 2009 event, we worked with the synthetic genomics vaccines + +37:06.580 --> 37:07.580 +Inc. + +37:07.580 --> 37:10.860 +One of Craig Viner's organizations and BARDA, part of the U.S. government. + +37:10.860 --> 37:16.900 +BARDA and the synthetic vaccine or synthetic genome, what did he say? + +37:16.900 --> 37:22.020 +So they're basically synthesizing, look, they're assembling oligos into flu gene segments + +37:22.020 --> 37:26.620 +enzymatically, rescuing flu viruses, they're designing and synthesizing. + +37:26.620 --> 37:32.500 +So they're doing, what I'm talking about, they're manufacturing viruses and they're + +37:32.500 --> 37:39.380 +making viral stocks using recombinant DNA and RNA technology in order to create viral + +37:39.380 --> 37:45.020 +stocks that are more homogenous than can be made with traditional culturing methods. + +37:45.020 --> 37:47.620 +That's my argument. + +37:47.620 --> 37:50.740 +It's not that I know the fine details. + +37:50.740 --> 37:54.420 +It's just that I know this is fundamental. + +37:54.420 --> 37:58.220 +It is a fundamental mythology of all RNA virology. + +37:58.220 --> 38:01.380 +That's what it is. + +38:01.380 --> 38:08.340 +And so here you hear him kind of talking around the fact that they are making synthetic clones + +38:08.340 --> 38:09.340 +of flu viruses. + +38:09.340 --> 38:11.700 +I'm going to back it up for a couple. + +38:11.700 --> 38:16.020 +Come up with the scenes, so while in research you may think in terms of years, in terms + +38:16.020 --> 38:20.020 +of outbreak and pandemic response, you have to think in terms of days. + +38:20.020 --> 38:21.020 +Next slide. + +38:21.020 --> 38:27.860 +In response to that in 2009 event, we worked with the Synthetic Genomics Vaccines Inc., + +38:27.860 --> 38:33.020 +one of Craig Vintner's organizations, and Bardev, I'm sorry, who Craig Vintner? + +38:33.020 --> 38:34.020 +Craig Vintner's organizations? + +38:34.020 --> 38:35.020 +I didn't hear that. + +38:35.020 --> 38:36.020 +Did I hear that correctly? + +38:36.020 --> 38:37.020 +Is that what he said? + +38:37.020 --> 38:38.020 +Hold on. + +38:38.020 --> 38:39.020 +Whoa. + +38:39.020 --> 38:40.020 +Whoa. + +38:40.020 --> 38:41.020 +Ah. + +38:41.020 --> 38:46.820 +In response to that in 2009 event, we worked with the Synthetic Genomics Vaccines Inc., + +38:46.820 --> 38:50.860 +one of Craig Vintner's organizations, and Bardev, part of the U.S. government, to come + +38:50.860 --> 38:56.940 +up with the Citizen Inc. 2009 event, we worked with the Synthetic Genomics Vaccines Inc., + +38:56.940 --> 39:01.060 +one of Craig Vintner's organizations, and Bardev, part of the U.S. government, to come + +39:01.060 --> 39:04.660 +up with the system to make vaccine viruses much faster. + +39:04.660 --> 39:11.900 +We synthesize the genes based on sequence available, the synthetic Genomics Vaccines + +39:11.900 --> 39:16.460 +Inc., one of Craig Vintner's organizations, and Bardev, the U.S. government, to come up + +39:16.460 --> 39:19.940 +with a system to make vaccine viruses much faster. + +39:19.940 --> 39:25.340 +We synthesize the genes based on sequence available, basically, on the web, and we use + +39:25.340 --> 39:30.100 +those to generate the viruses that we would use to make a vaccine. + +39:30.100 --> 39:33.460 +Did you hear what he just said? + +39:33.460 --> 39:40.460 +The system was based on genes that were synthesized from sequences found on the web. + +39:40.460 --> 39:48.500 +I mean, we synthesize the genes based on sequence available, basically, on the web, + +39:48.500 --> 39:52.340 +and we use those to generate the viruses that we would use to make a vaccine. + +39:52.340 --> 39:57.500 +We use those to generate the viruses. + +39:57.500 --> 40:03.380 +We use those to generate the viruses. + +40:03.380 --> 40:08.980 +So I think what you're missing here, and I think this is what Kevin and everybody on + +40:08.980 --> 40:15.420 +that side wants us to miss, is that packaging viruses is just transfecting things. + +40:15.420 --> 40:20.580 +That's what they do when they are transfected with these genomes. + +40:20.580 --> 40:21.580 +They make exosomes. + +40:21.580 --> 40:23.180 +They package stuff up. + +40:23.180 --> 40:28.420 +Sometimes the whole genome gets out, sometimes some garbage RNA from these subgenomic gets + +40:28.420 --> 40:29.420 +packaged. + +40:29.420 --> 40:34.180 +It doesn't matter because in the end, they're looking for a collective signal. + +40:34.180 --> 40:35.180 +If you... + +40:35.180 --> 40:37.740 +Do I have that on? + +40:37.740 --> 40:38.740 +Yeah. + +40:38.740 --> 40:44.100 +If you look at how they sequence something and you see, okay, here's the whole genome. + +40:44.100 --> 40:48.220 +And then when they do a sequencing reaction, and you'll see this in any paper that you + +40:48.220 --> 40:53.100 +look at, including the one where they sequence the first SARS genome, they'll have all kinds + +40:53.100 --> 40:54.660 +of fragments. + +40:54.660 --> 40:55.660 +And I get it. + +40:55.660 --> 40:56.660 +They overlap. + +40:56.660 --> 41:01.020 +And so when they overlap, then you can have all these sequences. + +41:01.020 --> 41:05.100 +In some places, they'll have lots of coverage, like here, when the end protein, they'll have + +41:05.100 --> 41:09.860 +lots of coverage of the end, very small coverage here, and maybe there's more coverage + +41:09.860 --> 41:14.500 +on this end of the genome, something like that, but they're all little tiny fragments. + +41:14.500 --> 41:17.420 +And then what they're doing is they're taking an average here. + +41:17.420 --> 41:19.620 +So here, they get this base a lot, right? + +41:19.620 --> 41:23.020 +So then they assume that this is a really good read. + +41:23.020 --> 41:25.340 +And then over here, this would be a really low read. + +41:25.340 --> 41:29.620 +And so they might have also a graph over here that looks like a confidence interval, and + +41:29.620 --> 41:31.420 +it'll get lower over here. + +41:31.420 --> 41:34.820 +And then they'll say that they're really sure about this part of the genome, and not + +41:34.820 --> 41:36.380 +so sure about this part of the genome. + +41:36.380 --> 41:42.820 +But then they'll still tell you that this is the sequence of the virus. + +41:42.820 --> 41:46.900 +They'll still tell you that this is the sequence of the virus, and this is the clone RNA that + +41:46.900 --> 41:49.820 +they will make with a coronavirus. + +41:49.820 --> 41:54.900 +And with flu, it's a bit more difficult because with flu, I believe there are eight segments + +41:54.900 --> 42:01.180 +of the genome that are thought to be circular and need to be regulated and copied separately. + +42:01.180 --> 42:04.500 +And so with flu virus, it's a little more complicated. + +42:04.500 --> 42:10.820 +And they're also flu viruses, um, bring their RNA into the nucleus, which is also really + +42:10.820 --> 42:14.940 +interesting because I don't think the coronaviruses do anything with the nucleus. + +42:14.940 --> 42:19.540 +So that's also a big difference between coronavirus and flu virus, but it's important to understand + +42:19.540 --> 42:24.700 +that what Dortmer at Mercer, or whatever his name is saying here, is that they worked + +42:24.700 --> 42:30.580 +with a company called Synthetic Genomics Vaccines, Incorporated. + +42:30.580 --> 42:31.580 +And that's with Venner. + +42:31.580 --> 42:35.980 +I might know if I'm spelling his name right, Craig Venner is the guy who wanted to build + +42:35.980 --> 42:41.340 +a whole database of full human genomes and then sell it back to the pharmaceutical companies. + +42:41.340 --> 42:46.140 +And so you could give him your, or he would sequence your whole genome for like $3,000 + +42:46.140 --> 42:52.420 +and then also use that as data that he could then, as a database sell back to, he's a really + +42:52.420 --> 42:53.420 +creepy dude. + +42:53.420 --> 42:59.100 +And he has been in really a trans human activist for a very, very long time. + +42:59.100 --> 43:02.860 +I have no doubt in my mind that anybody that worked on the Human Genome Project would have + +43:02.860 --> 43:05.380 +met Craig Venner at some point. + +43:05.380 --> 43:14.620 +Anyway, the BARDA partnered up with Novartis and with this company from Venner to synthesize + +43:14.620 --> 43:20.660 +the genes and make the viruses that they were going to make in the vaccines. + +43:20.660 --> 43:26.780 +And so, yeah, let's go back and see if we can keep this going. + +43:26.780 --> 43:29.340 +In theory, it would take about four and a half days. + +43:29.340 --> 43:31.420 +In fact, we had a test in which we did. + +43:31.420 --> 43:36.340 +In four and a half days, we went from genes being transmitted to us to a vaccine virus. + +43:36.340 --> 43:37.700 +Next slide. + +43:37.700 --> 43:39.620 +And we had a chance to be in three and a half days. + +43:39.620 --> 43:42.340 +In fact, make a vaccine is much faster. + +43:42.340 --> 43:47.460 +We synthesize the genes based on sequence available, basically on the web. + +43:47.460 --> 43:52.340 +And we use those to generate the viruses that we would use to make a vaccine. + +43:52.340 --> 43:54.900 +In theory, it would take about four and a half days. + +43:54.900 --> 43:57.380 +In fact, we went from four and a half days. + +43:57.380 --> 44:01.940 +In four and a half days, we went from genes being transmitted to us to a vaccine virus. + +44:01.940 --> 44:03.300 +Next slide. + +44:03.300 --> 44:06.220 +And we had a chance to actually implement that. + +44:06.220 --> 44:10.460 +In 2013, we went on April 1, Easter. + +44:10.460 --> 44:16.020 +We got a call saying that, in fact, there was this new H7N9 strain out in China, had + +44:16.020 --> 44:17.460 +caused fatalities. + +44:17.460 --> 44:23.700 +The Chinese CDC in a very far-thinking move put the sequence out on the web. + +44:23.700 --> 44:28.580 +By Monday, the genes were being synthesized, the gene synthesis in California completed + +44:28.580 --> 44:30.140 +by Tuesday. + +44:30.140 --> 44:35.180 +The genes synthesized, received in California for viral rescue on Wednesday and sent to + +44:35.180 --> 44:38.260 +the Centers for Disease Control for their response as well. + +44:38.260 --> 44:43.540 +By Saturday, we had the vaccine virus confirmed at any by the start of the next week. + +44:43.540 --> 44:45.980 +It was really fast. + +44:45.980 --> 44:47.580 +And then the next part starts. + +44:47.580 --> 44:48.780 +Next slide. + +44:48.780 --> 44:53.260 +All that activity is at the very beginning of that timeline you see there. + +44:53.260 --> 44:57.100 +This is the timeline from that same starting point when the sequences were posted on the + +44:57.100 --> 45:02.380 +web to where we started inoculating our first large-scale fermenter to make clinical trial + +45:02.380 --> 45:03.380 +material. + +45:03.380 --> 45:04.380 +It took months. + +45:04.380 --> 45:06.220 +It was not the science. + +45:06.220 --> 45:08.980 +It was, predominantly, the regulation. + +45:08.980 --> 45:10.780 +We couldn't do the work in the United States. + +45:10.780 --> 45:11.780 +Why? + +45:11.780 --> 45:15.180 +We couldn't get a USDA permit out of concerns at this virus, which actually doesn't cause + +45:15.180 --> 45:19.380 +disease and chickens might infect chickens. + +45:19.380 --> 45:20.940 +We had a lot of other issues as well. + +45:20.940 --> 45:25.820 +So we actually ended up doing this work primarily in Germany and then taking the vaccine back + +45:25.820 --> 45:30.820 +to the United States so that we could actually do the clinical trial. + +45:30.820 --> 45:36.380 +Germany is an interesting place to do it now, isn't it? + +45:36.380 --> 45:41.300 +Germany has not been on the sidelines of this pandemic narrative, not on the sidelines of + +45:41.300 --> 45:46.060 +the Western world's pandemic response in pandemic theater. + +45:46.060 --> 45:52.860 +Germany has been very high up there with regard to the games. + +45:52.860 --> 45:55.140 +Very high up there, sitting at the table very early. + +45:55.140 --> 46:01.060 +I find that very curious looking back from this perspective. + +46:01.060 --> 46:02.220 +Next slide. + +46:02.220 --> 46:05.820 +So why am I bringing all this stuff up and what's the relationship to gain a function + +46:05.820 --> 46:06.820 +research? + +46:06.820 --> 46:10.100 +In fact, there are little lessons scattered throughout this story. + +46:10.180 --> 46:15.060 +First, in those initial days when we got the sequence, did we use sequence motif data + +46:15.060 --> 46:18.020 +to guide what we were going to do to actually make a vaccine? + +46:18.020 --> 46:19.540 +The answer is yes. + +46:19.540 --> 46:25.420 +Now we certainly didn't use the transmissibility data because there is non-forage 7 and 9 + +46:25.420 --> 46:28.820 +and those data are complicated and at this point difficult to apply. + +46:28.820 --> 46:32.740 +But we did certainly look for a polybassy cleavage site and had there been one, we would have + +46:32.740 --> 46:34.060 +gotten rid of it. + +46:34.060 --> 46:41.260 +So there's a mention of a polybassy cleavage site and I do believe it is this actual talk + +46:41.260 --> 46:48.820 +oftentimes that is referenced by Charles Rixi as them admitting that fear and cleavage + +46:48.820 --> 46:52.580 +site is dangerous and that if they have it in a vaccine they remove it and this is some + +46:52.580 --> 46:55.820 +kind of big deal. + +46:55.820 --> 46:59.580 +I don't really think it is. + +46:59.580 --> 47:06.140 +It might make some for some reason or another, it might make the vaccine virus more toxic + +47:06.140 --> 47:13.540 +or more infectious or more difficult to attenuate or it might make it too immunogenic. + +47:13.540 --> 47:19.100 +I don't know but I don't think that it's some kind of up fear and cleavage site. + +47:19.100 --> 47:24.500 +Now it's a pandemic like a Carrington event. + +47:24.500 --> 47:28.740 +So be careful with that but it is here and he's going to say it again in a second. + +47:28.740 --> 47:33.780 +We also looked in the neuraminidase gene for markers of oseltamivir resistance and some + +47:33.780 --> 47:39.220 +of them we found them and we either did not synthesize those strains or we mutated those + +47:39.220 --> 47:45.020 +genes to eliminate the oseltamivir resistance in the vaccine strains that we made. + +47:45.020 --> 47:51.660 +So we did use genetic markers for phenotypic traits to affect what we actually made as + +47:51.660 --> 47:54.300 +the vaccine. + +47:54.300 --> 48:03.660 +Now the fact that in this case we're really slowed by very well intentioned regulations + +48:03.660 --> 48:06.860 +to protect basically the food supply in the United States. + +48:06.860 --> 48:10.100 +However that really meant that we could not in a timely way make the vaccine in the United + +48:10.100 --> 48:11.100 +States. + +48:11.100 --> 48:15.540 +Now no one who passed those regulations and forced them had the intention we're going + +48:15.540 --> 48:21.260 +to slow down human vaccine development however that was the effect. + +48:21.260 --> 48:26.100 +Had that been a high pathogenetic avian influenza strain we couldn't have done any + +48:26.100 --> 48:27.820 +of this work. + +48:27.820 --> 48:30.580 +Why? + +48:30.580 --> 48:33.180 +Regulations passed for the very good reasons they want to prevent people who have ill + +48:33.180 --> 48:38.340 +intention from doing bad things with the viruses basically select agent or regulations. + +48:38.340 --> 48:41.580 +What it meant we couldn't have synthesized this virus. + +48:41.580 --> 48:48.300 +Now you can't really put an entire manufacturing facility under select agent conditions and + +48:48.300 --> 48:53.620 +still have a factory that can produce seasonal vaccines in an economically competitive way. + +48:53.620 --> 48:58.620 +As a result we would have had to wait probably months to start the work, at least a month + +48:58.620 --> 48:59.900 +maybe more to start the work. + +48:59.900 --> 49:04.500 +Had it been a more severe strain had that poly basic cleavage site actually been present + +49:04.500 --> 49:05.900 +instead of absent. + +49:05.900 --> 49:12.100 +Again nobody who passed the select agent regulations that my goal is to endanger Americans and + +49:12.100 --> 49:14.780 +prevent the vaccines coming forward in a timely way. + +49:14.780 --> 49:15.780 +Is that the effect? + +49:16.100 --> 49:20.540 +Well we haven't had one of those yet but I can tell you from my company I couldn't do + +49:20.540 --> 49:28.660 +any of this technology if it were a high pathogenetic avian strain clearly counterproductive. + +49:28.660 --> 49:31.460 +If it were a high pathogen that would be solid. + +49:31.460 --> 49:33.580 +Thank you very much. + +49:33.580 --> 49:35.100 +Hey. + +49:35.100 --> 49:38.500 +Thank you. + +49:38.500 --> 49:41.900 +Thank you baby. + +49:41.900 --> 49:45.260 +Alright I got a little warm brownie and some coffee here. + +49:45.260 --> 49:47.180 +I wanted to say something about this. + +49:47.180 --> 49:48.980 +What did I want to say? + +49:48.980 --> 49:58.060 +What he's what he's explaining here is that the flu vaccine if it were to be aimed or + +49:58.060 --> 50:06.220 +be required to be aimed at a flu that had a poly basic cleavage site in it they would + +50:06.220 --> 50:14.780 +not be able to engineer that poly basic cleavage site into the vaccine strain because it wouldn't + +50:14.780 --> 50:15.780 +be allowed. + +50:15.780 --> 50:20.300 +So isn't that a strange isn't I really think we're hearing that correctly and I find that + +50:20.300 --> 50:27.540 +a very strange attitude because I thought that having a the poly basic cleavage site there + +50:27.540 --> 50:31.180 +would be terrible and that's why they would take it out. + +50:31.180 --> 50:38.380 +But what he's saying is that if they needed to put it in because a vaccine against a strain + +50:38.380 --> 50:43.580 +with a poly basic cleavage site was needed they wouldn't be able to do it and that would + +50:43.580 --> 50:50.020 +be a severe handicap to responding to a particularly virulent flu. + +50:50.020 --> 50:54.220 +I really think that's what we're hearing here which is really very very interesting. + +50:54.220 --> 51:03.420 +It's exactly wow that's that's funny 300,000 who pass the select agent regulations that + +51:03.420 --> 51:07.700 +my goal is to endanger Americans and prevent the vaccines coming forward in a timely way. + +51:07.700 --> 51:08.700 +Is that the effect? + +51:08.700 --> 51:13.460 +Well we haven't had one of those yet but I can tell you from my company I couldn't do + +51:13.460 --> 51:19.020 +any I couldn't apply any of this technology if it were a high pathogenicity, avian strain + +51:19.020 --> 51:21.620 +clearly counterproductive. + +51:21.620 --> 51:26.780 +If we were a high path even outbreak you saw there was 300,000 to 430,000 infections per + +51:26.780 --> 51:33.500 +week are prevented by every week of acceleration of vaccine supply if you got a 10 percent. + +51:33.500 --> 51:37.700 +Now that's a model right he's modeled if we got the vaccine out earlier than we could + +51:37.700 --> 51:43.100 +project that we would save this many lives that assumes probably a 100 percent of activity + +51:43.100 --> 51:48.100 +I mean it's our effectiveness of the vaccine it's really scary how he's talking right here + +51:48.100 --> 51:53.260 +because it's it's in a room full of virologists that are all buying into this as being pretty + +51:53.260 --> 51:59.620 +much okay when it's really just a lot of it's a lot of big talk that's it oh it's warm + +51:59.620 --> 52:00.620 +sweet. + +52:00.620 --> 52:05.100 +And to 50 percent mortality rate you can project that to the number of US deaths that would + +52:05.100 --> 52:08.580 +occur and you can extrapolate that to the rest of the world. + +52:08.580 --> 52:14.100 +So when I look at the gain of function debate I have a lot of sympathy for the notion that + +52:14.100 --> 52:17.980 +we there are certain experiments that are very very dangerous to do. + +52:17.980 --> 52:22.980 +I also know from a really practical pragmatic experience of trying to get vaccines out in + +52:22.980 --> 52:30.060 +real time that very well intentioned regulation has unintended consequences that can be quite + +52:30.060 --> 52:31.700 +severe. + +52:31.700 --> 52:36.700 +So if adaptation of vaccine viruses to increase growth in HA yield or the more modern synthetic + +52:36.700 --> 52:42.660 +equivalents of doing that in manufacturing when it captured by gain of function regulations + +52:42.660 --> 52:47.140 +or other precautions additional unintended impediments to the timely vaccine supply could + +52:47.140 --> 52:48.140 +be created. + +52:48.140 --> 52:50.220 +And I'll stop there. + +52:50.220 --> 52:52.700 +Okay thank you. + +52:52.700 --> 52:59.380 +Our next speaker is Ralph Berwick from University of North Carolina kind of the first slide. + +52:59.380 --> 53:03.740 +I'd like to start off by saying that no approved vaccines are therapeutics for SARS or MERS + +53:03.740 --> 53:09.260 +Coronavirus and we are currently in midst of an ongoing outbreak with about 950 cases + +53:09.260 --> 53:11.660 +and a 40 percent mortality rate. + +53:11.660 --> 53:12.660 +Next slide. + +53:12.660 --> 53:17.060 +I really want to focus on two stories one is how restrictions are reduced public health + +53:17.060 --> 53:21.940 +preparedness to respond to future SARS outbreaks and then I want to talk about how restrictions + +53:21.940 --> 53:29.660 +in animal model development will influence vaccine outcomes specifically noting the example + +53:29.660 --> 53:34.340 +of the vaccine it is to immune pathology associated with the SARS vaccine. + +53:34.340 --> 53:39.260 +And in the process I want to sort of debunk the idea that there are safe and alternative + +53:39.260 --> 53:44.700 +experiment approaches sometimes they give the wrong answers next slide. + +53:44.700 --> 53:46.460 +Whoa. + +53:46.460 --> 53:49.180 +Two stories. + +53:49.180 --> 53:52.100 +Restrictions will reduce public health preparedness. + +53:52.100 --> 53:55.900 +This is restrictions on gain of function. + +53:55.900 --> 54:02.340 +Functions on animal model development increases risk of vaccine induced immune pathology + +54:02.340 --> 54:06.540 +and mortality in human populations. + +54:06.540 --> 54:12.620 +So he thinks that he can save vaccine injuries by first using animal models to develop them. + +54:12.620 --> 54:19.300 +And finally he wants to debunk the concept that ethical and safe alternative experimental + +54:19.300 --> 54:24.500 +approaches exist that provide equivalent information is gain of function studies. + +54:24.500 --> 54:25.500 +That's cool. + +54:25.500 --> 54:27.260 +Everyone's here. + +54:27.260 --> 54:33.540 +So during the SARS outbreak of 2002, 2004 there are 8,000 cases and a 10 percent mortality + +54:33.540 --> 54:39.140 +rate and the original vaccine target included CIVIT and human strains that are about 99 percent + +54:39.140 --> 54:42.500 +identical and they're shown here on this sort of phylogenetic tree. + +54:42.500 --> 54:44.500 +Next slide. + +54:44.500 --> 54:46.980 +Since 2004 there's been no cases of SARS. + +54:46.980 --> 54:50.980 +Most of them think the viruses extinct in the wild. + +54:50.980 --> 54:58.420 +But as metagenomic sequencing has been applied, it's fairly clear that there are a large + +54:58.420 --> 55:02.700 +pool of related bad coronaviruses with 5 to 30 percent sequence difference in the spike + +55:02.700 --> 55:05.220 +like a protein which are shown right here. + +55:05.220 --> 55:09.860 +And there's been recognition in the field that vaccines and therapeutics not only need + +55:09.860 --> 55:15.820 +to target the epidemic strains, but they also have to be prepared to deal with pre-pandemic + +55:15.820 --> 55:17.660 +strains that might emerge in the future. + +55:17.660 --> 55:22.580 +And so the central question is are there other SARS-like strains that have pre-pandemic + +55:22.580 --> 55:23.580 +potential? + +55:23.580 --> 55:25.980 +And if so, we'll have vaccines and drugs. + +55:25.980 --> 55:31.580 +Here it's called pre-pandemic potential and it sounds like they dropped that P at some + +55:31.580 --> 55:32.580 +point. + +55:32.580 --> 55:33.580 +Let's work. + +55:33.580 --> 55:34.580 +Next slide. + +55:34.580 --> 55:39.660 +So we and others have synthesized the spikes of these genes shown here with the red arrows + +55:39.660 --> 55:44.220 +and then applied two different assays to ask questions about the pre-pandemic potential. + +55:44.220 --> 55:45.780 +Next slide. + +55:45.780 --> 55:50.700 +The first is using pseudotypes and so this is a safe ethical alternative approach that + +55:50.700 --> 55:54.500 +basically coats the virus and the spike and then you can ask whether any of these bad + +55:54.500 --> 55:58.420 +coronaviruses can use the humanase-2 receptor for entry. + +55:58.420 --> 56:03.940 +And if you look at the top part of that panel, you can see that the WIV-1 and the SARS coronavirus. + +56:03.940 --> 56:07.980 +I like how ethical alternative up there is in quotes, that's pretty funny. + +56:07.980 --> 56:12.780 +So you make a pseudovirus, I think they actually make pseudoviruses of the HIV virus or something + +56:12.780 --> 56:15.900 +which is comically ethical. + +56:15.900 --> 56:17.300 +I don't think that that's dangerous. + +56:17.300 --> 56:21.460 +I'm just saying how it appears to the lay person, it doesn't read better, that's for + +56:21.460 --> 56:22.460 +sure. + +56:22.460 --> 56:25.660 +Our strains both can use the humanase-2 receptor. + +56:25.660 --> 56:27.700 +WIV-1 is a bad coronavirus. + +56:27.700 --> 56:33.020 +It encodes three of the five contact interface sites that engage the ACE receptor so the + +56:33.020 --> 56:35.140 +data makes perfect sense. + +56:35.140 --> 56:39.020 +The other bad strains have much more variation and so it makes sense that they can't use + +56:39.020 --> 56:40.860 +the ACE-2 receptor. + +56:40.860 --> 56:44.820 +When you make chimeric viruses that encode these spike like a protein, this is part of + +56:44.820 --> 56:50.860 +the virus particle, notice that the SHCO-1-4 strain can now replicate efficiently in cells + +56:50.860 --> 56:54.340 +expressing the humanase-2 receptor. + +56:54.340 --> 56:59.500 +These data clearly indicate that pseudotypes and structure guided predictions, in which + +56:59.500 --> 57:05.020 +this case SHCO-1-4 contains the SHCO-1-4 strain can now... + +57:05.020 --> 57:19.620 +So this is the strain that he supposedly engineered to be lethal in mice. + +57:19.620 --> 57:21.180 +This is the lethal mouse strain. + +57:21.180 --> 57:30.860 +I think there's a paper about him doing this in B-L-B, bulb in a B-A-L-B mice and this + +57:30.860 --> 57:32.940 +is the strain here. + +57:32.940 --> 57:43.660 +And I believe that after that they took this and they... + +57:43.660 --> 57:47.300 +Yeah I can't remember anymore but this is definitely one of those that they played around + +57:47.300 --> 57:51.780 +with, that they got the idea, they got the spike from Wuhan and then they put it. + +57:51.780 --> 57:53.140 +They only had the spike. + +57:53.140 --> 58:00.020 +See is the chimeric virus recombinant virus and remember that a lot of these are incomplete + +58:00.020 --> 58:01.020 +sequences. + +58:01.020 --> 58:03.860 +So here's where it becomes very interesting. + +58:03.860 --> 58:09.500 +Let me just give you this little tidbit to think about. + +58:09.500 --> 58:13.740 +And we're just going to keep doing our work, we're not paying attention to these other + +58:13.740 --> 58:22.060 +clown cars behind us, we're in the cave all by ourselves here, because we're caverns + +58:22.060 --> 58:24.500 +ahead of these people. + +58:24.500 --> 58:29.060 +If you realize that when they sequence a virus in cell culture, they sequence a virus + +58:29.060 --> 58:36.500 +from a bronchial lavage that they get amplicons that sort like this hundreds and hundreds + +58:36.500 --> 58:43.940 +of them that are short amplicons over the 30,000 foot genome, 30,000 nucleotide genome. + +58:43.940 --> 58:44.940 +And so they never... + +58:44.940 --> 58:47.340 +They don't get full reads by any stretch of the imagination. + +58:47.340 --> 58:51.220 +When you're doing Sanger sequencing it could be between 300 and 1,000, maybe Kevin can + +58:51.220 --> 58:54.140 +correct me but it's not thousands. + +58:54.140 --> 58:58.900 +And indeed they need overlap on these amplicons so that they get multiple reads. + +58:58.900 --> 59:04.900 +And so these are amplified by PCR and the reason why they get more copies of some than + +59:04.900 --> 59:09.620 +the other ones is because these are more abundant and therefore they start amplifying earlier. + +59:09.620 --> 59:14.700 +That's the assumption that these people make and I don't think it's a terrible assumption. + +59:14.700 --> 59:20.260 +But then when they get a partial sequence, now this is the trick, if they get a partial + +59:20.260 --> 59:30.540 +sequence in the wild, the normal hot signal that you see here has just cut off at some + +59:30.540 --> 59:35.580 +arbitrary number where they don't have any coverage at these places. + +59:35.580 --> 59:41.740 +And so where you don't have coverage like here and from here to here and from here to + +59:41.740 --> 59:45.100 +here, then you're just missing those genomes. + +59:45.100 --> 59:47.660 +You're just missing that part of the genome. + +59:47.660 --> 59:57.700 +And with respect to the paper that he's talking about with this SHCO14S, he is assuming that + +59:57.700 --> 01:00:06.540 +because he has found in the wild a new coronavirus spike protein sequence, that that means that + +01:00:06.540 --> 01:00:08.860 +the entire coronavirus is a new one. + +01:00:08.860 --> 01:00:15.420 +It doesn't mean that it's part of a swarm, some of which have this spike protein. + +01:00:15.420 --> 01:00:21.740 +But he's assuming is that it's a whole new instance of this signal. + +01:00:21.740 --> 01:00:27.220 +And that's where they get all of these, these family trees and phylogenies from is that + +01:00:27.220 --> 01:00:35.140 +every time they find a new unique RNA signal for any of these 31 genes, it is very easy + +01:00:35.140 --> 01:00:38.060 +for them to say, wow, we found a new one. + +01:00:38.060 --> 01:00:43.580 +And assume again that just because it's so hard to find these, so hard to find these + +01:00:43.580 --> 01:00:48.140 +signals very robustly in nature and it's very hard to culture them because often time + +01:00:48.140 --> 01:00:50.660 +you only get a sample right here. + +01:00:50.660 --> 01:00:56.220 +You don't get any of these full genomes, they're rare. + +01:00:56.220 --> 01:01:00.860 +And so you can see what would happen if you started by transfecting or by losing or by + +01:01:00.860 --> 01:01:08.900 +creating your virus stock from a genomic RNA that was pure. + +01:01:08.900 --> 01:01:18.300 +Because then all of the clouds of incomplete genomes and subgenomic RNAs will start from + +01:01:18.300 --> 01:01:20.060 +a common ancestor. + +01:01:20.060 --> 01:01:26.860 +That's a very different scenario than a viral swarm that you would get from mother nature + +01:01:26.860 --> 01:01:30.580 +and a very much more infectious one. + +01:01:30.580 --> 01:01:36.100 +You can even imagine where it would decay exponentially from the first clone in clone + +01:01:36.100 --> 01:01:42.420 +transfection to maybe even a couple family members as that person shed self replicating + +01:01:42.420 --> 01:01:47.180 +full transcript RNAs. + +01:01:47.180 --> 01:01:51.020 +But the point to remember here is that when what they're talking about with regard to + +01:01:51.020 --> 01:01:57.420 +this paper is a sequence that the Wuhan lab found that was actually just a partial sequence + +01:01:57.420 --> 01:02:00.780 +that they found in the wild and they guessed that it looks like it's related, it looks + +01:02:00.780 --> 01:02:03.380 +like it's a SARS virus. + +01:02:03.380 --> 01:02:10.300 +And so with his technology, they were able to resurrect a laboratory version of it using + +01:02:10.300 --> 01:02:14.580 +a consensus coronavirus genome plus that spike. + +01:02:14.580 --> 01:02:19.460 +And that's where they got crazy with it. + +01:02:19.460 --> 01:02:26.900 +And that's where everybody went bananas in that 2015 paper. + +01:02:26.900 --> 01:02:27.900 +So here we go. + +01:02:27.900 --> 01:02:32.660 +They replicate efficiently in cells expressing the human ACE2 receptor. + +01:02:32.660 --> 01:02:37.820 +These data clearly indicate that pseudotypes and structure guided predictions in which + +01:02:37.820 --> 01:02:44.820 +this case, SHCl1.4 contains no conserved residues at the interface with any other known strain + +01:02:44.820 --> 01:02:47.500 +would have actually predicted the potential threat. + +01:02:47.500 --> 01:02:51.420 +It was actually a chimeric gain-of-function virus that did. + +01:02:51.420 --> 01:02:57.700 +And the SHCl1.4 and the WIV viruses grow equivalently to SARS and human airway epithelial cells. + +01:02:57.700 --> 01:03:00.300 +So there's no real gain of function in that phenotype. + +01:03:00.300 --> 01:03:01.660 +Next slide. + +01:03:01.660 --> 01:03:07.220 +If you look at virulence, these two bat SARS-like coronaviruses are attenuated. + +01:03:07.220 --> 01:03:09.460 +So you lose function. + +01:03:09.460 --> 01:03:15.900 +Vaccines, especially in the age models, do not protect against infection with these viruses. + +01:03:15.900 --> 01:03:19.620 +And there are four broadly cross-neutralizing human monoclonal antibodies that have been + +01:03:19.620 --> 01:03:22.980 +identified that neutralize all SARS and CIVIT strains. + +01:03:22.980 --> 01:03:27.620 +And none of them actually work against the SHCl1.4 virus. + +01:03:27.620 --> 01:03:35.500 +So what I hear here, and I hope you hear it here, is that he's making the argument that + +01:03:35.500 --> 01:03:39.340 +some of these viruses have no solution. + +01:03:39.340 --> 01:03:46.020 +And a live attenuated virus vaccine does not protect the animals. + +01:03:46.020 --> 01:03:53.340 +And a cocktail of monoclonal antibodies, like he described in 2007, very clear competitor + +01:03:53.340 --> 01:04:02.340 +intellectually, if you will, for the Z map product that was in Plumber's lab in Canada + +01:04:02.340 --> 01:04:05.740 +with that Chinese lady whose name I can't remember, but I'm sure Mark Koolack knows + +01:04:05.740 --> 01:04:07.700 +right off the top of his head. + +01:04:07.700 --> 01:04:13.100 +The point being here now, again, we're discussing the worst case scenario without actually saying + +01:04:13.100 --> 01:04:14.100 +it out loud. + +01:04:14.100 --> 01:04:18.220 +Because, again, we have something that vaccines won't work for, and a monoclonal antibody + +01:04:18.220 --> 01:04:19.820 +cocktail won't work for. + +01:04:19.820 --> 01:04:20.820 +And it's lethal. + +01:04:21.300 --> 01:04:24.860 +So human monoclonal antibodies that exist on a shelf will fail. + +01:04:24.860 --> 01:04:27.860 +We have no information on the transmissibility of these isolates. + +01:04:27.860 --> 01:04:29.500 +Next slide. + +01:04:29.500 --> 01:04:33.380 +So if you look at this phylogenetic tree, they fall into two clusters, that cluster with + +01:04:33.380 --> 01:04:40.100 +high risk strains, some of which, WIV1 and SHCl1.4, which actually are representative of about + +01:04:40.100 --> 01:04:43.180 +12 to 15 viruses, different viruses each. + +01:04:43.180 --> 01:04:45.100 +Yes, that lady, Jeff. + +01:04:45.100 --> 01:04:49.980 +There are no vaccines at therapeutics that will really work well against them, and so we're vulnerable. + +01:04:50.020 --> 01:04:53.980 +And I also want to mention that many of the chimeric viruses here, the definition implied + +01:04:53.980 --> 01:04:58.220 +in gain of function, is much too broad and must be redefined. + +01:04:58.220 --> 01:05:00.260 +Next slide. + +01:05:00.260 --> 01:05:02.780 +There are some public health implications to this research. + +01:05:02.780 --> 01:05:06.980 +On equivalently, it establishes that there are SARS-like viruses that are pre-positioned + +01:05:06.980 --> 01:05:15.300 +to jump and use human receptors and normal targets for infection, and so they have pre-pandemic + +01:05:15.300 --> 01:05:16.300 +potential. + +01:05:16.300 --> 01:05:20.900 +The results are generalizable to other coronaviruses and other zoonotic viruses, and there's a + +01:05:20.900 --> 01:05:25.260 +platform framework that you can use to tease those associations apart. + +01:05:25.260 --> 01:05:30.380 +And you can inform policymakers in terms of SARS-like outbreaks are possible and likely + +01:05:30.380 --> 01:05:35.940 +in the future, and that existing therapeutics and vaccines most likely will fail, and so + +01:05:35.940 --> 01:05:36.940 +we're unprepared. + +01:05:36.940 --> 01:05:41.620 +And advantage is that we have reagents now to derive effective interventions. + +01:05:41.620 --> 01:05:42.860 +Next slide. + +01:05:42.860 --> 01:05:47.260 +The second part I want to mention is the importance of animal model development in + +01:05:47.260 --> 01:05:49.020 +vaccine design. + +01:05:49.020 --> 01:05:52.580 +SARS replicates very poorly in mice. + +01:05:52.580 --> 01:05:56.340 +There's no weight loss or clinical disease and very little pathology. + +01:05:56.340 --> 01:06:00.260 +This is because the virus poorly engages the mouse ACE2 receptor. + +01:06:00.260 --> 01:06:02.540 +It doesn't use it very well. + +01:06:02.540 --> 01:06:06.860 +Every vaccine that I know of that's been tested in this replication model works. + +01:06:06.860 --> 01:06:11.140 +And then Kanta and her group at NIH developed some mouse-adapted strains, which have six + +01:06:11.140 --> 01:06:16.100 +to ten mutations that enhance the usage of the mouse ACE2 receptor. + +01:06:16.100 --> 01:06:18.020 +Next slide. + +01:06:18.020 --> 01:06:22.980 +This results in models that capture most of the human disease phenotypes, which are shown + +01:06:22.980 --> 01:06:24.300 +in yellow. + +01:06:24.300 --> 01:06:30.900 +And so I can't stress how it important it is to see what they are doing here is by establishing + +01:06:30.900 --> 01:06:41.020 +animal models, then they are going directly against that old adage that Robert Malone + +01:06:41.020 --> 01:06:46.620 +introduced us to or reminded us of way back when, which is mice lie, monkeys deceive + +01:06:46.620 --> 01:06:51.380 +and the only way to know the truth is humans. + +01:06:51.380 --> 01:06:59.500 +And in this scenario, what we are doing is setting ourselves up for a disaster by funding + +01:06:59.500 --> 01:07:04.780 +grant calls or rather writing grant calls and funding research proposals that look for + +01:07:04.780 --> 01:07:09.220 +development of animal models of disease. + +01:07:09.220 --> 01:07:15.740 +Animal models of disease being wholly inappropriate for studying viral replication, viral disease + +01:07:15.740 --> 01:07:18.100 +in humans. + +01:07:18.100 --> 01:07:24.060 +Because of the way that they do it, they use clones, they start with pure stocks and they + +01:07:24.060 --> 01:07:26.940 +apply it in crazy ways. + +01:07:26.940 --> 01:07:31.660 +Like really high concentrations in the nose or even worse, they inject it in the brain + +01:07:31.660 --> 01:07:39.140 +or somewhere in the heart muscle or in the interperitoneal cavity. + +01:07:39.140 --> 01:07:45.020 +And so these animal models are part of the voodoo part of the enchantment that has been + +01:07:45.020 --> 01:07:55.820 +cast on academia because he just said it in the previous slide that that unequivocally + +01:07:55.820 --> 01:08:02.580 +established that some natural SARS-like coronavirus strains are pre-pandemic potential. + +01:08:02.580 --> 01:08:04.140 +Unequivocally established. + +01:08:04.140 --> 01:08:10.980 +Now how is that any different than what I was saying right here with this early, but + +01:08:10.980 --> 01:08:17.620 +I want is that we're seeding the gain of function narrative with scientific programs + +01:08:17.620 --> 01:08:24.540 +in peer reviewed publications for years before the pandemic that what unequivocally, unequivocally + +01:08:24.620 --> 01:08:31.540 +established that some natural SARS-like coronavirus bad strains represent pre-pandemic potential. + +01:08:31.540 --> 01:08:35.900 +It's done, case closed. + +01:08:35.900 --> 01:08:38.620 +And now we need this warm base of manufacturing forever. + +01:08:38.620 --> 01:08:40.620 +Now we need to fund these programs forever. + +01:08:40.620 --> 01:08:42.580 +Now you can't argue anymore. + +01:08:42.580 --> 01:08:47.860 +You see what his job was? + +01:08:47.860 --> 01:08:51.460 +That's why they're throwing him under the bus now because that's what his job was. + +01:08:51.460 --> 01:08:57.740 +His job was established the worst case scenario and do your own thing alongside. + +01:08:57.740 --> 01:09:01.460 +And so he argued for what he thought was the legitimate best way. + +01:09:01.460 --> 01:09:07.380 +Had live attenuated viruses working on molecular solutions to de attenuation. + +01:09:07.380 --> 01:09:11.340 +These are all laudable pursuits. + +01:09:11.340 --> 01:09:14.300 +This is not the Scooby-Doo villain that we're looking for. + +01:09:14.300 --> 01:09:15.300 +Was he involved? + +01:09:15.300 --> 01:09:16.860 +Does he know who they are? + +01:09:17.340 --> 01:09:22.660 +I'm with almost without a doubt, he does. + +01:09:22.660 --> 01:09:30.660 +But the relentless focus on this man by people on social media, by people on the intellectual + +01:09:30.660 --> 01:09:38.180 +dark web, by people writing books is a mistake. + +01:09:38.180 --> 01:09:44.900 +It's a mistake because he's not JS Bach of coronaviruses because he used restriction + +01:09:44.900 --> 01:09:47.900 +enzymes to build a long DNA molecule. + +01:09:47.900 --> 01:09:52.540 +I mean, building a long DNA molecule with restriction enzymes was something that had + +01:09:52.540 --> 01:09:53.860 +already been done. + +01:09:53.860 --> 01:10:00.820 +Maybe not as long as a coronavirus genome, maybe. + +01:10:00.820 --> 01:10:06.980 +But it's not some kind of, you know, it's like adding a trailer to a semi-truck, you + +01:10:06.980 --> 01:10:10.340 +know, hey, you know what, you could hook up another trailer to the back of that. + +01:10:10.340 --> 01:10:11.340 +Really? + +01:10:11.340 --> 01:10:12.340 +I never thought about that. + +01:10:12.340 --> 01:10:13.340 +Holy cow. + +01:10:13.340 --> 01:10:14.340 +Does it work? + +01:10:14.420 --> 01:10:15.420 +You can hook another one up. + +01:10:15.420 --> 01:10:16.420 +Oh, wow. + +01:10:16.420 --> 01:10:19.940 +They call that a train. + +01:10:19.940 --> 01:10:28.180 +And so for this guy to be held up as some, you know, virtuoso, because he came up with + +01:10:28.180 --> 01:10:38.660 +the idea of using restriction enzymes to make a long DNA molecule, it's just ridiculous. + +01:10:38.660 --> 01:10:40.380 +But that's what they want, right? + +01:10:40.380 --> 01:10:41.380 +That's where we are. + +01:10:41.380 --> 01:10:42.380 +That's what they want. + +01:10:42.380 --> 01:10:43.380 +Rob's capyptor. + +01:10:43.380 --> 01:10:45.580 +It doesn't use it very well. + +01:10:45.580 --> 01:10:49.900 +Every vaccine that I know of that's been tested in this replication model works. + +01:10:49.900 --> 01:10:54.180 +And then Kanta and her group at NIH developed some mouse-adapted strains, which have six + +01:10:54.180 --> 01:10:59.220 +to ten mutations that enhance the usage of the mouse ACE2 receptor. + +01:10:59.220 --> 01:11:00.220 +Next slide. + +01:11:00.220 --> 01:11:05.940 +This results in models that capture most of the human disease phenotypes, which are shown + +01:11:05.940 --> 01:11:06.940 +in yellow. + +01:11:06.940 --> 01:11:09.940 +And a continual theme from these studies in terms of vaccines is that the Envivo core + +01:11:09.940 --> 01:11:12.940 +list of protection vary depending on the model. + +01:11:12.940 --> 01:11:13.940 +Next slide. + +01:11:13.940 --> 01:11:14.940 +Corillis of protection. + +01:11:14.940 --> 01:11:18.460 +The immediate vaccine was developed, purchased by NIH early in the epidemic. + +01:11:18.460 --> 01:11:21.660 +It protected mice and primates in a replication model. + +01:11:21.660 --> 01:11:25.100 +So what happens, although they did notice low levels of eosinophils in the animals, what + +01:11:25.100 --> 01:11:28.140 +happens after the lethal challenge strain is used? + +01:11:28.140 --> 01:11:31.180 +The vaccine fails to protect in the elderly, and it induces a TH2 immune pathology with + +01:11:31.180 --> 01:11:34.620 +a large number of eosinophils shown here by the column sort of in the middle, with all + +01:11:34.620 --> 01:11:36.860 +the blue cells surrounding the airways and the vesicles. + +01:11:36.860 --> 01:11:40.420 +And you can see that the number of eosinophils increased tenfold as a consequence of challenge. + +01:11:40.420 --> 01:11:41.420 +This is not a good thing. + +01:11:41.420 --> 01:11:42.420 +But it is an inbred model. + +01:11:42.420 --> 01:11:43.420 +What about outbred models? + +01:11:43.420 --> 01:11:44.420 +Next slide. + +01:11:44.420 --> 01:11:48.980 +So that's very similar to the paper that we looked at on the bike, actually, already + +01:11:48.980 --> 01:11:56.500 +in 2020, where they inoculated macaque monkeys and then exposed them to the virus, and they + +01:11:56.500 --> 01:12:01.900 +had a much more severe reaction to the virus, destroyed their lungs. + +01:12:01.900 --> 01:12:03.780 +This is exactly what he's describing here. + +01:12:03.780 --> 01:12:09.020 +It's very difficult to vaccinate against a coronavirus because inevitably what you've + +01:12:09.020 --> 01:12:16.380 +done is screw up the memory to the coronavirus and make your immune system prone to overreact + +01:12:16.380 --> 01:12:18.780 +to what it actually tries to ignore. + +01:12:18.780 --> 01:12:21.140 +It's actually pretty spectacular. + +01:12:21.140 --> 01:12:26.140 +So we use the collaborative cross mouse resource, which encodes the three substrains of mice. + +01:12:26.140 --> 01:12:30.460 +We took the eight founder lines and made 64 F1 dialyol combinations. + +01:12:30.460 --> 01:12:33.460 +We aged them for a year, vaccinated half of them, and then challenged the virus. + +01:12:33.460 --> 01:12:35.660 +This is about 2,400 mice total in this experiment. + +01:12:35.660 --> 01:12:36.660 +Next slide. + +01:12:36.660 --> 01:12:40.260 +When you look at the results in yellow, it means that the vaccine protected from lethal + +01:12:40.260 --> 01:12:41.260 +infection. + +01:12:41.260 --> 01:12:45.860 +Green is the vaccine protected either from lethal infection or pathology or disease. + +01:12:45.860 --> 01:12:49.700 +Black means that the vaccine really had little impact, and red means that the vaccine resulted + +01:12:49.700 --> 01:12:52.460 +in increased immune pathology and mortality in the animals. + +01:12:52.460 --> 01:12:55.020 +So in this case, in an outbred population, the prediction would be that that vaccine would + +01:12:55.020 --> 01:12:57.860 +have caused increased mortality in some individuals. + +01:12:57.860 --> 01:13:00.940 +This is seen with other vaccine formulations for SARS, this TH2 immune pathology. + +01:13:00.940 --> 01:13:07.140 +It demonstrates quite clearly the importance of animal model development in evaluating + +01:13:07.140 --> 01:13:09.420 +vaccine and drug performance. + +01:13:09.420 --> 01:13:10.420 +Last slide. + +01:13:10.420 --> 01:13:12.420 +Now in that sense, I agree with them. + +01:13:12.420 --> 01:13:18.700 +If the mice can already uncover massive failure of the vaccine product, then that's great. + +01:13:18.700 --> 01:13:21.980 +But if they would have survived, it wouldn't necessarily prove that it's going to work + +01:13:21.980 --> 01:13:23.380 +in humans. + +01:13:23.380 --> 01:13:27.900 +The pathology could have still developed in humans, or it could have been less obvious + +01:13:27.900 --> 01:13:29.700 +in the mice, et cetera. + +01:13:30.180 --> 01:13:34.500 +Remember, these mouse studies are always going to be ended early because they need to sacrifice + +01:13:34.500 --> 01:13:38.420 +the mouse in order to look at the tissue that they show those pictures of. + +01:13:38.420 --> 01:13:45.100 +So if the mouse model at six weeks would have shown no problems after re-infection or challenge, + +01:13:45.100 --> 01:13:48.820 +that wouldn't necessarily have proved definitively there wasn't going to be autoimmunity in the + +01:13:48.820 --> 01:13:49.820 +future. + +01:13:49.820 --> 01:13:51.700 +So that's another key thing to keep in mind. + +01:13:51.700 --> 01:13:53.940 +But where are we with MERS? + +01:13:53.940 --> 01:13:57.220 +MERS was not replicated mice or in any small animals, and vivo passage has failed in multiple + +01:13:57.220 --> 01:13:58.220 +laboratories. + +01:13:58.220 --> 01:14:00.100 +We'll talk about the reason for that tomorrow. + +01:14:00.100 --> 01:14:03.100 +Transgenic mice have been developed, expressing the human DPP4 receptor. + +01:14:03.100 --> 01:14:05.980 +This results in a replication model without serious disease. + +01:14:05.980 --> 01:14:09.300 +Passage of virus has been done in two laboratories, both of which, to our surprise, was halted + +01:14:09.300 --> 01:14:11.260 +in the midst of an ongoing epidemic. + +01:14:11.260 --> 01:14:15.540 +And so in our opinion, the public health vaccine development has been compromised by this decision. + +01:14:15.540 --> 01:14:18.180 +Without a robust small animal models, the testings of vaccines and drugs have been delayed + +01:14:18.180 --> 01:14:19.180 +and there's a backlog. + +01:14:19.180 --> 01:14:21.820 +So I think it's critical that MERS coronavirus restrictions be lifted immediately, at least + +01:14:21.820 --> 01:14:23.380 +in terms of animal model development. + +01:14:23.380 --> 01:14:24.380 +Last slide. + +01:14:24.380 --> 01:14:27.340 +So I'd just like to summarize where in dangerous times, there's four highly pathogenic viruses + +01:14:27.340 --> 01:14:28.940 +sort of sampling the human population. + +01:14:28.940 --> 01:14:32.420 +International travel allows for instantaneous, almost worldwide dissemination, and it's only + +01:14:32.420 --> 01:14:33.420 +going to get faster. + +01:14:33.420 --> 01:14:36.860 +And the response times, which are so critical for treating human disease, are being compressed. + +01:14:36.860 --> 01:14:41.140 +And being a function represents one of those approaches that is a crucial tool for public + +01:14:41.140 --> 01:14:42.740 +health preparedness and response. + +01:14:42.740 --> 01:14:50.940 +So that's an interesting place for Ralph Berwick to be when, again, and I think this is really + +01:14:50.940 --> 01:14:55.460 +important to see, where is it here? + +01:14:55.460 --> 01:14:56.460 +Is it here? + +01:14:56.460 --> 01:14:57.460 +Come on now. + +01:14:57.460 --> 01:14:58.460 +What the heck? + +01:14:58.460 --> 01:14:59.460 +I had it all queued up now. + +01:14:59.460 --> 01:15:00.460 +I don't see it tonight. + +01:15:00.460 --> 01:15:01.460 +Oh, yeah, here. + +01:15:01.460 --> 01:15:02.460 +Sorry, got it. + +01:15:02.460 --> 01:15:03.460 +Got it. + +01:15:03.460 --> 01:15:04.460 +Got it. + +01:15:04.460 --> 01:15:05.460 +Let's just watch this one really quick. + +01:15:05.460 --> 01:15:06.460 +Okay. + +01:15:06.460 --> 01:15:15.100 +And then I'm only going to watch the beginning and then I'm going to hang out because I got + +01:15:15.100 --> 01:15:17.220 +to go to my son's basketball game. + +01:15:17.220 --> 01:15:18.220 +Check this out. + +01:15:18.220 --> 01:15:19.620 +Thank you, Andy. + +01:15:19.620 --> 01:15:22.260 +Just listen to the beginning of this because the beginning is hysterical. + +01:15:22.260 --> 01:15:23.260 +That was really nice. + +01:15:23.260 --> 01:15:27.660 +As an now person, I really admire at the school. + +01:15:27.660 --> 01:15:28.660 +Ralph Berwick. + +01:15:28.660 --> 01:15:33.260 +He's the most accomplished and prolific scientist anywhere and he's really brought tremendous + +01:15:33.260 --> 01:15:37.260 +creativity, persistence, and innovation to the study of viruses. + +01:15:37.260 --> 01:15:40.820 +I've had the opportunity to tour his lab. + +01:15:40.820 --> 01:15:47.060 +So we watched the 2007 video yesterday and then we just watched the 2016 video and now + +01:15:47.060 --> 01:15:50.980 +we're going to watch him talk two years later. + +01:15:51.980 --> 01:15:52.980 +Okay. + +01:15:52.980 --> 01:15:53.980 +And microbiology and immunology. + +01:15:53.980 --> 01:15:54.980 +Two years later. + +01:15:54.980 --> 01:15:55.980 +No. + +01:15:55.980 --> 01:15:56.980 +The NIN. + +01:15:56.980 --> 01:16:01.620 +How bad could the next pandemic be? + +01:16:01.620 --> 01:16:02.620 +What might it look like? + +01:16:02.620 --> 01:16:03.620 +And will we be ready? + +01:16:03.620 --> 01:16:08.620 +Well, I have to admit, I'm a little worried about giving this talk partially because as + +01:16:08.620 --> 01:16:11.460 +Yogi Barris said, it's tough to make predictions, especially about the future. + +01:16:11.460 --> 01:16:13.540 +So there's a good chance I could be wrong. + +01:16:13.540 --> 01:16:19.100 +I study coronaviruses, noroviruses, flaviviruses, and do some influenza virus research just to + +01:16:19.100 --> 01:16:20.940 +give you some background of what I do. + +01:16:20.940 --> 01:16:25.820 +The other reason that I'm a little bit worried is being labeled as a harbinger of doom. + +01:16:25.820 --> 01:16:26.820 +This is not me. + +01:16:26.820 --> 01:16:29.500 +I'm not one of the four horsemen of the apocalypse. + +01:16:29.500 --> 01:16:32.060 +So he's choosing to do this, right? + +01:16:32.060 --> 01:16:38.020 +Or is he implying that someone else is making him give this talk from this perspective as + +01:16:38.020 --> 01:16:42.100 +one of the four horsemen of the apocalypse, the plague? + +01:16:42.100 --> 01:16:48.100 +It's a very curious talk to me because it is not a typical scientific talk. + +01:16:48.100 --> 01:16:55.060 +The typical lecture from a biologist has a 30,000 foot view directly over the target + +01:16:55.060 --> 01:16:57.500 +and then you zoom in. + +01:16:57.500 --> 01:17:04.780 +You don't start from the, you know, wow, I mean, from worst case scenario. + +01:17:04.780 --> 01:17:10.180 +Even if you think that Alzheimer's disease is really important or you think that autism + +01:17:10.180 --> 01:17:17.580 +is a really devastating disease, you don't start with worst case scenario. + +01:17:17.580 --> 01:17:20.260 +And yet here he is, and it's extraordinary. + +01:17:20.260 --> 01:17:22.980 +And I want you to let you know that I'm really kind of a nice guy. + +01:17:22.980 --> 01:17:26.340 +So please come talk to me after this talk. + +01:17:26.340 --> 01:17:30.820 +I will mention that viruses are certainly in the pockets of all of the four horsemen and + +01:17:30.820 --> 01:17:33.340 +they can be used in all of these scenarios. + +01:17:33.340 --> 01:17:36.820 +So I'd like to start off by taking a step back and talk about how infectious diseases + +01:17:36.820 --> 01:17:41.900 +ranks or stacks up against other natural disasters that in terms of frequency and relative risk. + +01:17:41.900 --> 01:17:46.140 +So if you step back and every three to 400 million years or so, there's a danger of + +01:17:46.140 --> 01:17:47.660 +a gamma radiation burst. + +01:17:47.660 --> 01:17:50.340 +These occur when black holes and neutron stars collide. + +01:17:50.340 --> 01:17:53.980 +It shoots out this burst of gamma radiation which can strip away the ozone layer. + +01:17:53.980 --> 01:17:57.660 +It's acid rain, resulting high UV radiation levels to plant an animal life on the planet + +01:17:57.660 --> 01:17:59.180 +and will result in global warming. + +01:17:59.180 --> 01:18:02.420 +And this can occur as far as 6,500 light years away. + +01:18:02.420 --> 01:18:03.980 +Fortunately, it doesn't happen so often. + +01:18:03.980 --> 01:18:07.100 +So I'm not, don't really lose sleep about this at night. + +01:18:07.100 --> 01:18:11.500 +A little bit more likely to cause an issue as an asteroid strike. + +01:18:11.500 --> 01:18:15.340 +The earth runs into about 3,700 to about 7,800 tons of debris. + +01:18:15.340 --> 01:18:18.140 +As it flows through space, occasionally some of these are big rocks. + +01:18:18.140 --> 01:18:21.940 +When a really big rock hits the planet, this can result in an extinction level event like + +01:18:21.940 --> 01:18:23.220 +what happened to the dinosaurs. + +01:18:23.220 --> 01:18:25.820 +The good news is that mammals became dominant and so we are here today. + +01:18:25.820 --> 01:18:29.980 +Otherwise we'd probably be lunch. + +01:18:29.980 --> 01:18:33.700 +The U.S. takes this threat fairly seriously so NASA has a near earth object program that + +01:18:33.700 --> 01:18:36.980 +tracks satellites that are large enough to cause damage to the planet. + +01:18:36.980 --> 01:18:39.540 +One problem that they face is they can only track them for about 100 years and the accuracy + +01:18:39.540 --> 01:18:40.540 +falls off. + +01:18:40.540 --> 01:18:43.180 +But fortunately Bruce Willis, our mom, get it in here. + +01:18:43.180 --> 01:18:45.380 +I just want to point out that he is also a Pensberg boy. + +01:18:45.380 --> 01:18:46.380 +We actually went to school together. + +01:18:46.380 --> 01:18:48.340 +It's a little town in New Jersey, 3,500 of us. + +01:18:48.340 --> 01:18:52.460 +A clear epicenter of planetary defense, so remember that, please. + +01:18:52.460 --> 01:18:54.660 +Anyway, moving up on the list, we have supervolcanoes. + +01:18:54.660 --> 01:18:55.660 +I do like Bruce Willis. + +01:18:55.660 --> 01:18:57.220 +We went there about every million years. + +01:18:57.220 --> 01:18:59.540 +We watched Die Harder the other day with my boys. + +01:18:59.540 --> 01:19:00.700 +That was pretty funny. + +01:19:00.700 --> 01:19:03.620 +These are volcanoes that are large enough to co-continent with about a half an inch of + +01:19:03.620 --> 01:19:05.300 +ash or more. + +01:19:05.300 --> 01:19:10.060 +Supervolcanoes, which was in Indonesia, resulted in ice age and knocked the... + +01:19:10.060 --> 01:19:12.780 +And look at that, that's Yellowstone right there. + +01:19:12.780 --> 01:19:16.660 +About 20 of these of concern on the planet, and this is ours, this is Yellowstone, obviously. + +01:19:16.660 --> 01:19:19.020 +Please go to the caldera and spend some time at that hotel. + +01:19:19.020 --> 01:19:20.020 +It's quite a treat. + +01:19:20.020 --> 01:19:23.180 +Finally, we have Carrington-level events, which probably some of you may have heard + +01:19:23.180 --> 01:19:24.180 +of. + +01:19:24.180 --> 01:19:25.180 +Most people, not these are geomagnetic storms. + +01:19:25.180 --> 01:19:31.420 +When solar flares throw off a lot of coronal mass, they can hit our electromagnetic waves + +01:19:31.420 --> 01:19:34.700 +that are around the earth and this can result in magnetic storms. + +01:19:34.700 --> 01:19:36.460 +The biggest one occurred in 1859. + +01:19:36.460 --> 01:19:39.980 +It wasn't much electronics at the time, but it caused fires and telegraph offices. + +01:19:39.980 --> 01:19:42.700 +It shocked our electrocuted telegraph workers. + +01:19:43.180 --> 01:19:46.580 +Much smaller ones occurred in the 60s and 70s at knockout power grids in the U.S. and + +01:19:46.580 --> 01:19:47.580 +Canada. + +01:19:47.580 --> 01:19:51.100 +Lloyd's of London says that they can cause about $23 million in damage and potentially + +01:19:51.100 --> 01:19:52.620 +knock out the power grid for one to five years. + +01:19:52.620 --> 01:19:54.260 +So this is not insignificant. + +01:19:54.260 --> 01:19:57.460 +And what's a little bit scary is that much larger flares are possible. + +01:19:57.460 --> 01:20:01.020 +So NASA has taken this pretty seriously, and if the first solar probe is going to go around + +01:20:01.020 --> 01:20:03.700 +the sun, it's going to be launched in the summer, and they are going to take a look + +01:20:03.700 --> 01:20:04.700 +at this. + +01:20:04.700 --> 01:20:07.620 +But this can certainly knock out GPS, cell phone, internet, and power grid for several years. + +01:20:07.620 --> 01:20:10.300 +Okay, so now we're back into infectious diseases. + +01:20:10.300 --> 01:20:11.300 +Here we are. + +01:20:12.300 --> 01:20:15.300 +From my perspective, though, since I've been on the planet, there's been an epidemic + +01:20:15.300 --> 01:20:17.580 +virus every decade starting with Asian flu in 1960. + +01:20:17.580 --> 01:20:19.900 +So do you see Asian flu? + +01:20:19.900 --> 01:20:20.900 +And then... + +01:20:20.900 --> 01:20:25.300 +In Hong Kong in 1967 or 1968, H1N1 came back in the 70s, followed by HIV, followed by + +01:20:25.300 --> 01:20:27.540 +West Nile, and then we got to the 21st century. + +01:20:27.540 --> 01:20:28.540 +And thanks, Spada. + +01:20:28.540 --> 01:20:31.260 +SARS was the first epidemic virus of the 20... + +01:20:31.260 --> 01:20:40.700 +Now here he doesn't actually mention the Spanish flu, but he did mention it in the talk + +01:20:40.700 --> 01:20:45.860 +from 2007, and said how many people had killed. + +01:20:45.860 --> 01:20:50.780 +So here we again are starting with this idea of worst case scenario, we're starting with + +01:20:50.780 --> 01:20:56.220 +the idea of pandemic potential, but extraordinarily, he is doing something that I think a lot of + +01:20:56.220 --> 01:21:00.220 +these gain-of-function people have done, especially since the start of the pandemic, + +01:21:00.220 --> 01:21:06.940 +and start to make equivalences with very, very planet-wide devastating events, rather + +01:21:06.940 --> 01:21:12.940 +than bring it down to a nuclear weapon, or bring it down to a few thousand people, we + +01:21:12.940 --> 01:21:20.740 +have to bring it up into orders of magnitude more impactual, like a meteor, or a Carrington + +01:21:20.740 --> 01:21:27.260 +event that would knock out the entire power grid of the Northern Hemisphere for five years. + +01:21:27.260 --> 01:21:33.940 +And so I cannot stress enough how important it is for you to see that this slide, describing + +01:21:33.940 --> 01:21:38.140 +what we are witnessing here, is so real. + +01:21:38.140 --> 01:21:41.740 +They definitely seeded the gain-of-function narrative with scientific programs. + +01:21:41.740 --> 01:21:46.660 +They knew what they were doing, and they co-opted people like Ralph Berwick with lots and lots + +01:21:46.660 --> 01:21:53.380 +of funding to do whatever the heck he wanted with translation regulatory sequences and trying + +01:21:53.380 --> 01:21:57.460 +to make attenuated viruses that couldn't de-attenduate. + +01:21:57.460 --> 01:22:03.260 +They let him do everything he wanted with that, as long as they also got the stitching + +01:22:03.260 --> 01:22:04.260 +thing to go. + +01:22:04.260 --> 01:22:11.660 +Got synthetic viruses and coronaviruses to go, and in fact, it's even possible that these + +01:22:11.660 --> 01:22:17.460 +things are just, they're just testing self-replicating RNA on us and calling them coronaviruses and + +01:22:17.460 --> 01:22:21.820 +normal viruses and flavoviruses and all this other stuff. + +01:22:21.820 --> 01:22:27.560 +None of these have perhaps have a significant natural signature, but the signature that + +01:22:27.560 --> 01:22:32.620 +we are told to pay attention to, the signature that they wave around all the time, could actually + +01:22:32.620 --> 01:22:43.020 +be always generated from a laboratory-created manufactured clone RNA. + +01:22:43.020 --> 01:22:44.020 +That's the reality. + +01:22:44.020 --> 01:22:45.900 +It could be. + +01:22:45.900 --> 01:22:50.060 +The reality is not that it could be that there are millions of viruses out there in + +01:22:50.060 --> 01:22:55.260 +the wild and that there are pandemics happening and avoided all the time. + +01:22:55.260 --> 01:23:00.780 +That's at least the idea that we are using clones all the time and making clones and + +01:23:00.780 --> 01:23:05.660 +that that's the only danger is at least as equally likely as the opposite. + +01:23:05.660 --> 01:23:10.100 +This worst-case scenario narrative, which I'm sure in my heart of hearts, it really feels + +01:23:10.100 --> 01:23:13.900 +like it doesn't have a firm foundation in biology. + +01:23:13.900 --> 01:23:21.460 +Again, you can find the entire gain of function symposium on usatonicits.com's website under + +01:23:21.460 --> 01:23:24.500 +the gain of function symposium 2016. + +01:23:24.500 --> 01:23:29.380 +All of those are also hosted on a YouTube channel, and then the individual video that + +01:23:29.380 --> 01:23:34.660 +we watched is also right there. + +01:23:34.660 --> 01:23:35.660 +So we have been... + +01:23:35.660 --> 01:23:37.860 +What I want is time morbidity. + +01:23:37.860 --> 01:23:39.100 +I want people to complain. + +01:23:39.100 --> 01:23:41.300 +By these people. + +01:23:41.300 --> 01:23:43.020 +And I think it is the best. + +01:23:43.020 --> 01:23:48.500 +It's really fabulous that Sacha Latopova has found James Giordano and realizes how pivotal + +01:23:48.500 --> 01:23:49.500 +this lecture is. + +01:23:49.500 --> 01:23:54.780 +I'm so happy that she's also trying to call out Robert F. Kennedy Jr. to make sure that + +01:23:54.780 --> 01:24:00.540 +we try to keep pushing him forward, to keep retrospectively looking at the pandemic + +01:24:00.540 --> 01:24:07.020 +for evidence from other fields and evidence from other data sets to prove or disprove + +01:24:07.020 --> 01:24:10.340 +the spread of a risk-additive pathogen in 2020. + +01:24:10.340 --> 01:24:15.860 +And I think we can get him over the edge to understand that infectious RNA clones is + +01:24:15.860 --> 01:24:20.380 +the only real threat in modern RNA virology. + +01:24:20.380 --> 01:24:26.180 +And again, that's because infectious material is very hard to come by by any other means. + +01:24:26.180 --> 01:24:32.980 +And we have been bamboozled by a spectacular commitment to this lie. + +01:24:32.980 --> 01:24:36.580 +Some people have been coerced, some people have been wittingly and unwittingly... + +01:24:36.580 --> 01:24:38.620 +Oh yeah, I wanted to show you that. + +01:24:38.620 --> 01:24:40.300 +I mean, isn't that crazy? + +01:24:40.300 --> 01:24:47.820 +Have you ever heard this language before, anywhere else, besides... + +01:24:47.820 --> 01:24:48.820 +Let me see if it's here. + +01:24:48.820 --> 01:25:07.100 +Did I copy it or did I wittingly or unwittingly? + +01:25:07.100 --> 01:25:09.420 +Here it is right here at the top. + +01:25:09.420 --> 01:25:15.060 +All pandemics to date have been faked by the military industrial globalist cabal with numerous + +01:25:15.060 --> 01:25:20.260 +witting and unwitting participants. + +01:25:20.260 --> 01:25:21.660 +I mean, I'm not... + +01:25:21.660 --> 01:25:22.740 +I don't care. + +01:25:22.740 --> 01:25:24.860 +I really don't. + +01:25:24.860 --> 01:25:31.060 +But I'm just wondering if anybody else that's watching the show right now sees any striking + +01:25:31.060 --> 01:25:37.700 +resemblance to the message that I've been sending for the last year, year and a half or so. + +01:25:37.700 --> 01:25:39.340 +Four ways to fake the... + +01:25:39.340 --> 01:25:45.420 +Easy ways to fake the pandemic, Spanish-fluous fake, John Bodman's good, Meryl Nasse and + +01:25:45.420 --> 01:25:50.740 +Lab Leaks, then witting and unwitting participants. + +01:25:50.740 --> 01:25:52.780 +RFK doesn't have it quite right yet. + +01:25:52.780 --> 01:25:55.100 +I actually have that in his book. + +01:25:55.100 --> 01:25:57.380 +And then also James Giordano. + +01:25:57.380 --> 01:25:59.460 +It's really interesting to me. + +01:25:59.460 --> 01:26:03.180 +But witting and unwitting participants is... + +01:26:03.180 --> 01:26:06.060 +I guess it's a pretty common phrase in English. + +01:26:06.060 --> 01:26:07.220 +I guess that's possible. + +01:26:07.220 --> 01:26:08.220 +I don't know. + +01:26:08.220 --> 01:26:11.660 +Anyway, here we are, ladies and gentlemen. + +01:26:11.660 --> 01:26:17.420 +It's been a fun, fun, fun time and it is only just starting. + +01:26:17.420 --> 01:26:24.900 +My 52nd year, the entire year is probably going to be spent trying to make sure that + +01:26:24.900 --> 01:26:28.140 +your kids and mine do not get on this train. + +01:26:28.140 --> 01:26:34.380 +The your kids and mine learned the truth that Alex Berenson said live on Joe Rogan that, + +01:26:34.380 --> 01:26:39.540 +you know, if you had to invest in one thing, it would be in sewage and in water treatment + +01:26:39.540 --> 01:26:43.820 +in sanitation because that's where we got the most gains. + +01:26:43.820 --> 01:26:48.260 +He's not going to go so far as to say that we didn't need vaccines, that we wouldn't + +01:26:48.260 --> 01:26:53.340 +have needed vaccines to have that huge reduction in polio and measles and other transmissible + +01:26:53.340 --> 01:26:58.540 +disease when we got nutrition up and we got water treatment up and we got sewage treatment + +01:26:58.540 --> 01:27:00.620 +up and we got water purity up. + +01:27:00.620 --> 01:27:05.700 +Hello. + +01:27:05.700 --> 01:27:12.940 +And they definitely don't want us to understand the extent of the coronavirus illusion. + +01:27:12.940 --> 01:27:19.260 +How little fidelity that they really have, how over exaggerated this signal has been + +01:27:19.260 --> 01:27:21.860 +and how unmonitored it was before the pandemic. + +01:27:21.860 --> 01:27:23.980 +So we can free our college kids. + +01:27:23.980 --> 01:27:29.380 +We can free our children and prevent our grandchildren from ever getting on this train in the first + +01:27:29.380 --> 01:27:30.380 +place. + +01:27:30.380 --> 01:27:32.460 +We have to teach our children the way out. + +01:27:32.460 --> 01:27:37.340 +We have to teach them the biology that will free them to make sure that this lie never + +01:27:37.340 --> 01:27:38.700 +becomes the truth. + +01:27:38.700 --> 01:27:42.900 +They must learn the biology because then it can't happen. + +01:27:42.900 --> 01:27:46.180 +And that biology describes this as a Scooby-Doo. + +01:27:46.180 --> 01:27:51.380 +We were fooled into believing that something leaked in 2009 by all the lies and the redacted + +01:27:51.380 --> 01:27:54.460 +emails and the arguing in front of the Senate. + +01:27:54.460 --> 01:27:58.220 +And for five years, we've been fooled by this illusion of consensus that people think + +01:27:58.220 --> 01:28:02.420 +that this is the right question to ask, that it's either a lab leak or a natural virus + +01:28:02.420 --> 01:28:06.300 +and getting mad about it and this faith that there was a virus, this faith that millions + +01:28:06.300 --> 01:28:09.820 +of people died, this is the danger, this is the mythology. + +01:28:09.820 --> 01:28:13.980 +We cannot pass on to our children or they will be lost forever and more importantly, + +01:28:13.980 --> 01:28:15.580 +our grandchildren will be. + +01:28:15.580 --> 01:28:17.340 +This faith is a lie. + +01:28:17.340 --> 01:28:18.940 +It was a background. + +01:28:18.940 --> 01:28:21.260 +It was an amplified noise. + +01:28:21.260 --> 01:28:24.020 +It was a signal that was planted there. + +01:28:24.020 --> 01:28:31.540 +It was not a natural occurrence. + +01:28:31.540 --> 01:28:37.060 +It was not a natural occurrence, like the spilling of a signal in one place and spreading from + +01:28:37.060 --> 01:28:38.060 +a point. + +01:28:38.060 --> 01:28:40.020 +That's not how it happened. + +01:28:40.020 --> 01:28:42.420 +And yet that's what we are told. + +01:28:42.420 --> 01:28:44.860 +That's what every one of these people believes. + +01:28:44.860 --> 01:28:50.060 +That's what every one of these people is defending, including Kevin McCurnan. + +01:28:50.060 --> 01:28:55.980 +Because the clone chemtrail hypothesis is, it's chemtrail retarded. + +01:28:55.980 --> 01:29:01.980 +The biology is the way out cause first call for a stop to the childhood vaccine schedule + +01:29:01.980 --> 01:29:07.620 +in America by simply advocating for it to be compared to other Western countries and + +01:29:07.620 --> 01:29:14.220 +acknowledge that it's too early and too many and therefore it has to be criminal advocate + +01:29:14.220 --> 01:29:18.820 +for strict liability for these products because that's the way that we fix this problem. + +01:29:18.820 --> 01:29:22.380 +Investigate the use of deadly protocols to cause mass casualty events. + +01:29:22.380 --> 01:29:28.820 +That's Jessica Hockett, that's Jonathan Engler, that's Martin Neal. + +01:29:28.820 --> 01:29:32.340 +Investigate the use of mass casualty events and transfection to create the illusion of + +01:29:32.340 --> 01:29:34.180 +a pandemic. + +01:29:34.180 --> 01:29:39.500 +And that we can talk to Pierre Corey and Nurse Aaron and all these other people that were + +01:29:39.500 --> 01:29:44.740 +supposedly there during the worst time but actually weren't and we're not really sure + +01:29:44.740 --> 01:29:47.340 +what they were doing. + +01:29:47.340 --> 01:29:50.780 +So we need to claim sovereignty over our children's bodies again, we need to get out + +01:29:50.780 --> 01:29:54.620 +of the who, we need to get out of the UN, we need to close our CDC. + +01:29:54.620 --> 01:29:57.420 +And you can see these people because they won't say these things. + +01:29:57.420 --> 01:30:02.140 +Pierre Corey said that all childhood vaccinations were bad at some point on Jimmy Dorr. + +01:30:02.140 --> 01:30:05.620 +So I think we should watch that video to see what else he says. + +01:30:05.620 --> 01:30:07.540 +But they won't advocate for strict liability. + +01:30:07.540 --> 01:30:14.380 +You won't hear any of these lawyers at ICANN like, like Siri say, we should just advocate + +01:30:14.380 --> 01:30:15.460 +for strict liability. + +01:30:15.460 --> 01:30:20.660 +You won't hear Siri say that we should go against this from the Seventh Amendment perspective + +01:30:20.660 --> 01:30:22.540 +and try to get it struck in federal court. + +01:30:22.540 --> 01:30:25.940 +You won't hear them say that because it's maybe not the right time or something. + +01:30:25.940 --> 01:30:27.740 +I don't know. + +01:30:27.740 --> 01:30:30.220 +You're not going to hear them talk about the deadly protocols. + +01:30:30.220 --> 01:30:32.060 +They're always going to now going forward. + +01:30:32.060 --> 01:30:34.420 +They're always going to focus on the vaccine. + +01:30:34.420 --> 01:30:38.100 +And that's what you saw when they co-opted Denny Rancor's data. + +01:30:38.100 --> 01:30:41.340 +They exclusively focused on the 17 million number. + +01:30:41.340 --> 01:30:46.100 +Now you have people calling out Brett Weinstein is saying that 17 million number, the 17 + +01:30:46.100 --> 01:30:47.620 +million number is dumb. + +01:30:47.620 --> 01:30:50.500 +And you have Brett Weinstein say, well, I didn't say 17 million. + +01:30:50.500 --> 01:30:53.380 +I was just quoting somebody else. + +01:30:53.380 --> 01:30:58.380 +And all the while everybody ignores the John Bodewin and Denny Rancor and Jessica Hawkett + +01:30:58.380 --> 01:31:03.620 +and Jonathan Engler all have data from all around the world that shows there was no spreading + +01:31:03.620 --> 01:31:06.620 +pathogen. + +01:31:06.620 --> 01:31:10.820 +They don't use the word clone because it's going to reveal the fact that RNA virology + +01:31:10.820 --> 01:31:17.820 +in and of itself is foundationally dependent on this methodology and therefore is overextended + +01:31:17.820 --> 01:31:23.900 +is exaggerated and likely most are all of the objections laid out by Stefan Lanka and the + +01:31:23.900 --> 01:31:28.220 +Bailey's and all these people are likely true. + +01:31:28.220 --> 01:31:32.100 +And so you're damn right I was taken. + +01:31:32.100 --> 01:31:35.900 +And so as I admit this, they make fun of it as I admit this people are coming on. + +01:31:35.900 --> 01:31:37.820 +Well, why didn't you just vaccinate your kids? + +01:31:37.820 --> 01:31:38.820 +Yeah, I did. + +01:31:38.820 --> 01:31:39.820 +I admitted it. + +01:31:39.820 --> 01:31:42.900 +I lied about it and I'll do it again. + +01:31:42.900 --> 01:31:46.180 +Cry about it, that is. + +01:31:46.180 --> 01:31:48.540 +It's these other people who say I just made honest mistakes. + +01:31:48.540 --> 01:31:54.460 +I don't have anything to apologize for just because I advocated for masks for two years, + +01:31:54.460 --> 01:31:58.340 +just because I advocated for lockdown for two years, just because I said it was a gain + +01:31:58.340 --> 01:31:59.700 +a function virus for two years. + +01:31:59.700 --> 01:32:04.500 +I don't have any obligation to learn virology for myself so that I don't make a mistake + +01:32:04.500 --> 01:32:08.620 +to my hundreds of thousands of viewers. + +01:32:08.620 --> 01:32:11.260 +That's what these people think. + +01:32:11.260 --> 01:32:12.580 +That's not what we're doing here though. + +01:32:12.580 --> 01:32:16.460 +We're teaching this biology now and we're going to keep teaching it as we try to do study + +01:32:16.460 --> 01:32:18.540 +halls to figure it out together. + +01:32:18.540 --> 01:32:23.060 +We're going to try and summarize across the entire show and we're going to attack ideas + +01:32:23.060 --> 01:32:24.180 +instead of people. + +01:32:24.180 --> 01:32:28.560 +That's how we're going to get out of this because they are trying to reduce the population + +01:32:28.560 --> 01:32:33.140 +and they are going to do it by just not letting our kids think it's a cool thing to + +01:32:33.140 --> 01:32:40.780 +have have kids to show you commercials on YouTube about being a single woman with + +01:32:40.780 --> 01:32:48.140 +no kids and how great it is or on rumble because they don't want us to have kids. + +01:32:48.140 --> 01:32:50.380 +They want the population to go down. + +01:32:50.380 --> 01:32:55.820 +They really do but as it goes down, they also want you to surrender. + +01:32:55.820 --> 01:32:57.620 +They want our kids to surrender. + +01:32:57.620 --> 01:33:02.380 +More importantly, more importantly, the way to say it is they want us to surrender our + +01:33:02.380 --> 01:33:07.900 +children because they think that the artificial general intelligence is just right around + +01:33:07.900 --> 01:33:08.900 +the corner. + +01:33:08.900 --> 01:33:12.460 +So they got to collect this data so that they can feed it and so that it can figure + +01:33:12.460 --> 01:33:13.660 +out how the genome works. + +01:33:13.660 --> 01:33:19.420 +It can figure out all the irreducible complexity that we've never been able to penetrate. + +01:33:19.420 --> 01:33:24.060 +Ladies and gentlemen, stop all transfections in humans because they are trying to eliminate + +01:33:24.060 --> 01:33:30.620 +the control group by any means necessary intramuscular injection of any combination of substances + +01:33:30.620 --> 01:33:33.340 +with the intent of augmenting the immune system is dumb. + +01:33:33.340 --> 01:33:37.620 +Transfection in healthy humans is criminally negligent and viruses are not patterned integrity. + +01:34:00.620 --> 01:34:07.620 +Thank you very much guys, thank you very much for joining me and thanks for the birthday + +01:34:07.620 --> 01:34:08.620 +wishes. + +01:34:08.620 --> 01:34:09.620 +I will have a good time. + +01:34:09.620 --> 01:34:11.060 +I'm going to watch this game. + +01:34:11.060 --> 01:34:17.740 +I coached already this morning early and came back and I did the stream and I got the eighth + +01:34:17.740 --> 01:34:22.260 +graders, the eighth grade boy he plays but I'm not his coach. + +01:34:22.260 --> 01:34:26.740 +If you would like to support the stream, please go to gigglehomebiological.com. + +01:34:26.740 --> 01:34:30.980 +If you'd like to communicate with me there, you can find a telephone number, you can + +01:34:30.980 --> 01:34:38.340 +also find an email, you can find me at gigglehome.bio which is kind of like a Twitter alternative. + +01:34:38.340 --> 01:34:42.660 +You can support Gigglehome there at the green, you can find this link at the watch and then + +01:34:42.660 --> 01:34:47.900 +of course there's a schedule and then down at the bottom there's places to subscribe. + +01:34:47.900 --> 01:34:50.740 +I can't thank everybody enough for jumping on board. + +01:34:50.740 --> 01:34:53.380 +I will not let you down this year. + +01:34:53.380 --> 01:34:56.940 +These subscribers are contributing to what I think is going to be the most important + +01:34:56.940 --> 01:35:03.740 +or one of the most important independent news streams on the internet in the coming year + +01:35:03.740 --> 01:35:09.660 +and I think Mark, who's a tonic live and myself and a few other people are starting + +01:35:09.660 --> 01:35:17.460 +to form what is a loose, you know, intellectual bright web on the internet and I'm really + +01:35:17.460 --> 01:35:21.220 +excited and I really have these people and more to thank for that. + +01:35:21.220 --> 01:35:27.620 +So thank you very much for joining me and if you have the means and the opportunity + +01:35:27.620 --> 01:35:31.740 +I have a drink for me, please, 52 years old, see you tomorrow. + diff --git a/twitch/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief/README.md b/twitch/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief/README.md new file mode 100644 index 0000000..bec0897 --- /dev/null +++ b/twitch/2046478249 (2024-01-28) - Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief/README.md @@ -0,0 +1,5 @@ +# Potential Benefits of GOF Research II (Study Hall) -- (28 Jan 2024) -- Gigaohm Biological High Resistance Low Noise Information Brief + +## Streams +- https://twitch.tv/videos/2046478249 +