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10506 lines
237 KiB
10506 lines
237 KiB
12 months ago
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You
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03:42.000 --> 03:49.000
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Senator Ron John, nice work Albert I think he's a very very astute man I think he's really in in it for the real fight so
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03:49.000 --> 03:55.000
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I'm happy to hear you connected with him he's actually asked me for an update that I still haven't written
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03:55.000 --> 04:01.000
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He's scheduled for 60 minutes playing the reference your work so it's good that you've already made him I'm really happy to hear that
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Japanese television people everywhere are starting to listen to him it's embarrassing
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You
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Oh
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No one will believe
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You
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06:25.000 --> 06:40.000
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Good evening ladies and gentlemen this is Gigo and biological a high resistance low noise information brief brought to you by biologists the 13th of November
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06:40.000 --> 06:53.000
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2023 we are still fighting to escape this limited spectrum of debate this critical and dissonant views within it that have been falsely amplified to give us this perceived
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06:53.000 --> 07:10.000
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perceived vision of what is true from these people to mislead the young and yeah I'm I'm really really stoked that we're made so much progress and I'm really happy that you guys are a part of it
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07:10.000 --> 07:20.000
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But we got to take the power back from these skeletons we do we have to take the power back from these charlatans I have the feeling my voice is a little hot
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07:20.000 --> 07:27.000
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I see the bricks I hope you guys do
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07:27.000 --> 07:39.000
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I got to tell you the week and a half off of my voice has done wonders for it it has now progressed quite a bit let me just read these off really quick
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07:39.000 --> 07:48.000
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There was no spread in New York City infectious clones are the only real threat placebo batches were like distributed in transfection and healthy mammals is dumb
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07:48.000 --> 07:56.000
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We can go farther and say that the protocols were murder gave a function as a mythology the scooby-doo mystery is real and the players are committed to lies
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07:56.000 --> 08:03.000
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and the lies are very specifically about this the lies
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08:03.000 --> 08:07.000
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oh that's not the way I can do that
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08:07.000 --> 08:22.000
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the novel virus is a fate the fact that millions of people died and millions more were saved that's a fate
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08:22.000 --> 08:30.000
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the idea that gain of function is a real danger that's a fate and the idea that a virus a pandemic is definitely going to come again
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08:30.000 --> 08:40.000
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that's a fate that's a fate that's not anything based in reality it's not anything based in biology and that is really where we are
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08:40.000 --> 08:51.000
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modified mRNA definitely modified are in our RNA destroyed cardio myocytes and any other cell that it expresses itself in
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08:51.000 --> 09:09.000
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biology we really have to not take the bait on TV and social media if you think this is something now it's nothing compared to what they're going to throw at us
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09:10.000 --> 09:30.000
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I am going to have the event a episode 2 it is coming don't underestimate it's just a question of everything falling in place but there will be a clone war episode 2 for sure
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09:30.000 --> 09:35.000
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and I guess here we are
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09:35.000 --> 09:39.000
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let me see if I can shift over here without too much
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09:39.000 --> 09:41.000
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hassle
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09:41.000 --> 09:48.000
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good evening ladies and gentlemen welcome to the show this is Giga Home Biological a high-resistance low-noise information brief brought to you by a biologist
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09:48.000 --> 09:55.000
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my name is Jonathan Cooley and I'm coming to you from live from the back of my garage in Pittsburgh, Pennsylvania
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09:55.000 --> 10:03.000
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I'm happy to be here I took a week off after well more than a week off it was almost two weeks off actually
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10:03.000 --> 10:13.000
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partly to rest my voice partly because I was traveling and partly because I've been transitioning into this role as a basketball coach
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10:13.000 --> 10:21.000
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and so I needed to kind of figure out okay how is this going to impact my evenings how is this going to impact my streaming
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10:21.000 --> 10:31.000
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how is that schedule going to work and more importantly what kind of stress does it put on my partner my wife my best friend in terms of bedtime and everything
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10:31.000 --> 10:40.000
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so I think we're kind of settling around this this attractor state which is around nine or eight thirty
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10:40.000 --> 10:48.000
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it's a lot better if I'm around for my sons to get them in bed and get their phones away from them and on the charger
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10:48.000 --> 10:57.000
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to get the TV off early this kind of thing don't judge me my kids are like your kids they do actually have phones
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10:57.000 --> 11:04.000
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they don't have a lot of stuff on them but there's enough on them so that you know their phone is a little annoying at times
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11:04.000 --> 11:14.000
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and so they're not allowed to use it very much they use it for Spotify a lot but you know after dinner when what's on the TV is not what they're interested in watching
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11:14.000 --> 11:27.000
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or when someone else has control those are when the phone they tend to disappear to their rooms with their phone and so it's a lot easier to do that together as mom and dad
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11:27.000 --> 11:36.000
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and so I don't think there are going to be very many streams that happen in the weekdays before eight or unless they're before dinner
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11:36.000 --> 11:45.000
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and then we could we're talking about four in the afternoon or five in the afternoon that's also possible in fact I expect that window to be pretty useful for basketball practice days
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11:45.000 --> 11:54.000
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but I think I'm officially starting another streak of streams right now which means that we could be looking at you know a few a few in a row
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11:54.000 --> 12:02.000
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certainly daily and there very few are going to be in the morning most of them are going to be in the afternoon either before dinner or after dinner
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12:03.000 --> 12:10.000
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in case it's not clear intramuscular injection of any combination of substances with the intent of augmenting the immune system is dumb
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12:10.000 --> 12:19.000
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and transfection healthy humans is criminally negligent you either know how bad it is and you shouldn't recommend it for your patients
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12:19.000 --> 12:27.000
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or you didn't know how bad it was and then you were criminally negligent this is my new sort of wording I'm trying to adjust this a little bit
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12:27.000 --> 12:32.000
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so you could adjust it a little more and you could just say that intramuscular injection of any combination of substances
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with the intent of augmenting the immune system of healthy humans including transfection and transformation is criminally negligent
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12:42.000 --> 12:52.000
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there now we've got it I think that's pretty straightforward I don't think you need to have 40 doctors at a conference and spend four days on stage
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12:52.000 --> 13:06.000
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to try and explain the biological basis for this stance and I think that any biologists worth their salt in any field of academia any branch of academic investigation
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I invite you to come on my stream and challenge this notion come on this stream and explain why intramuscular injection is a really bright way of trying to augment the immune system
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and how it is that your combination of substances overcomes what is clearly in a broad sense one of the most ridiculous ideas we've ever applied in modern science
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13:32.000 --> 13:42.000
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I know this seems like a really crazy stance to take but I have been ahead of this for a while and I'm afraid I'm ahead of this one as well
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I mean it's all of these excuses being made for when this might be appropriate or what we have to do to make intramuscular injection an appropriate way of augmenting the immune system but there is no way to do it
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13:57.000 --> 14:06.000
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and there is a precise way of speaking about transfection and I think it's worth speaking about transfection in that precise way
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transfection of healthy humans is criminally negligent I think that's a great way to speak but if you want to make one statement not two I think we can also say it this way
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14:16.000 --> 14:31.000
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there is no useful way of augmenting the immune system via intramuscular injection it's just a dumb idea on its face and we should have known this many many many years ago and in fact I should edit that statement
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14:31.000 --> 14:42.000
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many people have known this for a very long time are my audio sync out okay well then we're just going to stop and start again if you guys don't mind because I just did this so
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14:42.000 --> 14:46.000
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I'll start with this slide let me think here
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yeah I'll just start with this slide right here I'll be right back see you soon
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how are we doing piano fab does this look better
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15:20.000 --> 15:37.000
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all right great so welcome to the show again this is giggle and biological high resistance low noise information brief brought to you by a biologist it's the 13th of November 2023 and we are still fighting
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in this same basic battle and battle really focuses on messaging precise messaging right now I think the main job of everybody that's in this theater is to obfuscate the truth
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15:54.000 --> 16:11.000
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and the truth that we've learned over the last three years is that the public health apparatus of America and around the world has been organized over the last couple decades to produce what is effectively a world wide theater
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16:11.000 --> 16:30.000
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and a worldwide theater designed to sort of invert the way that we think about our sovereignty and to start to make us think that mother nature presents so many different dangers that the only way that we can really exist as a global community is to submit to this public health apparatus
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16:31.000 --> 16:41.000
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and the way that we get rid of this idea the way that we fight this idea is to teach our children the biology which underpins these two statements right here there
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16:42.000 --> 16:50.000
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and the two statements are that intramuscular injection of any combination of substances with the intent of augmenting the immune system is dumb
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and more specifically for the context within which we find ourselves the transfection in healthy humans is criminally negligent
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and we have to be very precise here because one of the current temptations has to do with criminal negligence but then the circumstances around which the legal establishment of that is being made is a false one
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and again this is about trying to make sure that we don't ask the correct questions because the correct questions are the way that we escape
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and so as long as we keep chasing down the wrong villains and pull in the masks off of the wrong people then we're never going to solve this mystery
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but it is the act of unmasking these people it is the act of having solved the mystery of the lab leak that has bamboozled the entire globe into thinking that we did have a pandemic of a novel virus that millions of people died from it but millions more were saved
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and then gain a function is real and probably the source of this pandemic and therefore it's likely to come again that's a faith that we have been bamboozled into believing through the use of bad language and bad theater
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intramuscular injection of any combination of substances with the intent of augmenting the immune system of a healthy human
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including transfection and transformation is criminally negligent and I say it a little differently here because I guess there is a way where you might want to augment the immune system of a sick human
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to try and make that sick humans immune system fight off cancer better that's a pretty limited thing that is not a healthy human it's a human that's going to die anyway
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and so there are limited uses for it but if you if you use precise language we can describe exactly that which we object to
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and I would argue that a lot of these people in the intellectual dark web although they talk really big with their big words like heterodoxy
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they actually speak very imprecisely about the exact things the exact ideas
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from which our enchantment is constructed and we are indeed enchanted by these people enchanted by the ideas that they have woven together in a false reality
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it is a illusion of consensus that is created by these ideas that they have woven together with the help of social media with the help of mainstream media
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and a coordinated effort by themselves not to question the faith in a novel virus that killed millions of people but also millions of people were saved from
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and likely came from gain of function and therefore will come again
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19:57.000 --> 20:06.000
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and so I've been finding out about the intellectual dark web and how coordinated they have been how on message they've been in real time
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and in fact two years too late because I thought Brett Weinstein was kind of a hero for a while
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I thought he was actually listening to me
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I even thought that him casually mentioning my name every once in a while on the stream was somehow him finally giving me attention
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20:23.000 --> 20:31.000
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little did I know that he's never retweeted anything he's never really promoted a website or a link that would get anybody to me he's never spelled my name
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he's never shown a picture and he certainly never had me on his podcast
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we're just talking about a lot of liars here ladies and gentlemen I don't know who's lying and who doesn't know better
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and I'm not going to make any accusations like that but I'm quite I'm quite certain
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the vast majority of people that have been elevated in social media that have risen during the pandemic
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even risen through censorship these people have been artificially so and their rise is far from organic
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in much the same way that people like Mark Hewson tonic Mark Coolack after four years of producing consistent output on YouTube still has like what six thousand followers
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and it's not for a lack of consistency or lack of integrity or anything like that it's for artificially the spread of the information is artificially hampered
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dominoes are taken out of the train in random places and it prevents the natural spread of the information by attention and excitement
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and I think that actually people imagine that one part of this equation happens but the other part doesn't when in reality both happen
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and actually it's more important that those dominoes are taken out of the way so that even when people share your work it doesn't catch
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that's much more important level of control in the on the algorithm level than it is to say artificially inflate somebody because if it's garbage
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if it's garbage information it's not going to have the it's not going to have the inertia that that truth has
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in fact that's why a lot of these people that are involved in the intellectual dark web need to deal in a soup of truth and untruth
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half truth and bad questions because they have to walk very carefully around the truth so that it feels genuine from some superficial standpoint
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and there are other players and other layers that are responsible for a similar part of the total effect of the worst case scenario team
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is the best way that I can describe them everybody in the intellectual dark web everybody in all the corners of the internet
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all the people that got little help on social media and most of the people who seem to get tips in the beginning of the pandemic about a fear and cleavage site
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or about the effectiveness of remdesivir and they were months ahead of these sort of crucial notions of the worst case scenario being possible
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the worst case scenario being a lab leak possible you know ridiculous infectiousness of a virus that had a fear and cleavage site
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these cartoon stories and mythologies were seeded very early on in several different places and several different heads and several different corners on the internet
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and people were allowed to write books about these ideas in order to amplify them early as one side of a narrative
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and you had to figure out by removing the masks of these bad guys by catching them in lies by reading their partially redacted emails
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you were supposed to feel like you were solving the puzzle
|
||
|
|
||
|
24:16.000 --> 24:26.000
|
||
|
and yet none of these people in all of their research were ever able to find this article from 2004
|
||
|
|
||
|
24:27.000 --> 24:36.000
|
||
|
where they just say the silent stuff out loud in their introduction nobody nobody in the intellectual dark web
|
||
|
|
||
|
24:37.000 --> 24:51.000
|
||
|
not Sam Harris or Brett Weinstein or Kevin McCann or Charles Ricksey or Andrew Huff or Robert Malone or where were all these people
|
||
|
|
||
|
24:52.000 --> 25:01.000
|
||
|
why aren't they bringing up the fact that the head of the National Cancer Institute and his postdoc wrote a article about
|
||
|
|
||
|
25:02.000 --> 25:09.000
|
||
|
from genome to vaccine where they state the market for vaccines is driven by perception not by actual need
|
||
|
|
||
|
25:10.000 --> 25:18.000
|
||
|
so unlike pharmaceuticals for which present illness drives demand it is the perception of risk of diseases that creates a desire for vaccination
|
||
|
|
||
|
25:22.000 --> 25:30.000
|
||
|
this is written in 2004 this is what they say behind closed doors when they admit that this is a business
|
||
|
|
||
|
25:32.000 --> 25:40.000
|
||
|
when they admit that yeah you know water sanitation washing hands and soap and this kind of stuff yeah it made a big difference
|
||
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|
||
|
25:41.000 --> 25:49.000
|
||
|
yeah aseptic technique that made a big difference yep antibiotics huge difference yep better medicine better treatments
|
||
|
|
||
|
25:50.000 --> 25:59.000
|
||
|
better food better nutrition all made a big difference yep yep but in front of the camera and in front of the grant committee
|
||
|
|
||
|
26:01.000 --> 26:08.000
|
||
|
they usually say that well you know vaccines are the best thing ever you know it's like the pyramids and vaccines and airplanes
|
||
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|
||
|
26:09.000 --> 26:12.000
|
||
|
best inventions like just a short list
|
||
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|
||
|
26:13.000 --> 26:22.000
|
||
|
and so that's how you can tell that these people are full of it that's how you can tell if you look at somebody like Peter McCullough who's come from
|
||
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|
||
|
26:23.000 --> 26:34.000
|
||
|
you know being full blown allopathic just mainstream doctor to being on podcasts now saying that if he was raising a kid now he wouldn't have any vaccines in that kid
|
||
|
|
||
|
26:35.000 --> 26:47.000
|
||
|
now that's progress that's growth that's realizing the reality in front of you and the consequences of all of the data points that you have in front of you
|
||
|
|
||
|
26:48.000 --> 27:00.000
|
||
|
there's no other conclusion to come to and it's really important to realize that in this Scooby-Doo everybody's going to have to come to their own realization of how bad it is
|
||
|
|
||
|
27:01.000 --> 27:16.000
|
||
|
and when Peter McCullough was on my stream he hadn't yet come that far he might have come that far in private but not in person and everybody I'm predicting everybody is going to have to come that far
|
||
|
|
||
|
27:17.000 --> 27:24.000
|
||
|
and if you don't make it you will be part of the trap you will be part of the reason why humanity is lost
|
||
|
|
||
|
27:25.000 --> 27:39.000
|
||
|
because coming to that realization that realization that is that is really described perfectly by Peter McCullough saying that you know if I was to start all over again and have kids again I don't think I would I would forgo the vaccine schedule
|
||
|
|
||
|
27:40.000 --> 27:53.000
|
||
|
so that's giant and right now the Scooby-Doo and all of the people who have perpetuated the Scooby-Doo on us whatever the right word is enacted it in order to fool our children
|
||
|
|
||
|
27:54.000 --> 28:03.000
|
||
|
those people are in their last place the theater is a visible thing now the bricks are visible some of the lights are out
|
||
|
|
||
|
28:04.000 --> 28:21.000
|
||
|
some of the theater lights have come on and so the the production is being exposed it's really just a question of how stubborn is the majority of the members of the audience and how can we force them to see it to acknowledge it
|
||
|
|
||
|
28:22.000 --> 28:34.000
|
||
|
that we were duped that we were duped by our whole government by that even that performance by Rand Paul and Tony Fauci in 2020 was a duping they did that to us
|
||
|
|
||
|
28:35.000 --> 28:44.000
|
||
|
that wasn't two guys acting like good guys trying to do their best to figure it out and Tony was lying to Rand
|
||
|
|
||
|
28:45.000 --> 29:01.000
|
||
|
that was a performance that was a carefully orchestrated performance and it was designed to do exactly what it did solidify the support for Fauci on all the people who were on his team
|
||
|
|
||
|
29:02.000 --> 29:10.000
|
||
|
and solidify the support against or the opposition to Fauci in this the suspicion of a lab leak cover up on the other side
|
||
|
|
||
|
29:11.000 --> 29:15.000
|
||
|
and make both of those teams convinced that they are right
|
||
|
|
||
|
29:16.000 --> 29:20.000
|
||
|
it was the one of the most beautiful things I had ever seen
|
||
|
|
||
|
29:21.000 --> 29:24.000
|
||
|
and as I watched it live I knew it was baloney
|
||
|
|
||
|
29:25.000 --> 29:35.000
|
||
|
but I couldn't quite understand how the baloney was being used I couldn't understand it as a Scooby-Doo that they were fooling an entire planet
|
||
|
|
||
|
29:36.000 --> 29:48.000
|
||
|
into thinking that they were catching a liar or that a hero was being mistreated and no matter which narrative you chose you lose
|
||
|
|
||
|
29:49.000 --> 29:56.000
|
||
|
because then you have chosen that there is a novel virus it's definitely killing a lot of people we definitely need to do something
|
||
|
|
||
|
29:56.000 --> 30:04.000
|
||
|
it's probably going to function it could come again you accepted it all we including me accepted it all
|
||
|
|
||
|
30:05.000 --> 30:08.000
|
||
|
and we spent two years arguing about that
|
||
|
|
||
|
30:09.000 --> 30:16.000
|
||
|
well a lot of us did I spent about four months arguing about that before I realized that that argument meant nothing
|
||
|
|
||
|
30:17.000 --> 30:24.000
|
||
|
because the biology of coronavirus the biology of RNA viruses doesn't support the idea of a pandemic
|
||
|
|
||
|
30:25.000 --> 30:34.000
|
||
|
it doesn't support the idea of a uniformly spreading RNA signal over multiple years and multiple waves
|
||
|
|
||
|
30:35.000 --> 30:41.000
|
||
|
there's no support for this there's no biological basis for this other than the stories that are told and introductions
|
||
|
|
||
|
30:42.000 --> 30:47.000
|
||
|
and discussions of a few science papers scientific papers around the world that's it
|
||
|
|
||
|
30:48.000 --> 31:00.000
|
||
|
you can't even really find the biology that supports this in a in anything but but an introduction where they are where they are waxing intellectual about things that don't exist
|
||
|
|
||
|
31:01.000 --> 31:11.000
|
||
|
but what we're starting to learn from this pattern and I think it's really important to see this what we're learning from this pattern is that we may have been governed like this for many decades
|
||
|
|
||
|
31:12.000 --> 31:25.000
|
||
|
and they just have lied about other things in the same way that we're starting to wake up to the idea that what if what if other government proceedings have been performances
|
||
|
|
||
|
31:26.000 --> 31:36.000
|
||
|
what if other government scandals have been performances what if other other government controversies have been performances
|
||
|
|
||
|
31:37.000 --> 31:48.000
|
||
|
and that's where this whole narrative starts to fall apart that's where we as Americans need to start to take responsibility for governing our country again
|
||
|
|
||
|
31:49.000 --> 31:53.000
|
||
|
we've got to take responsibility and take back our republic again
|
||
|
|
||
|
31:55.000 --> 32:02.000
|
||
|
because we can't expect them to do it because remember the people that coming to the rescue are also part of the show
|
||
|
|
||
|
32:03.000 --> 32:09.000
|
||
|
until we are rescuing ourselves we are allowing the show to continue
|
||
|
|
||
|
32:13.000 --> 32:22.000
|
||
|
I want you to watch this video again because I want to remind you of the kind of semantic war that they are waging on us
|
||
|
|
||
|
32:23.000 --> 32:38.000
|
||
|
the big problem in vaccines has been that while it's been possible in the past to make vaccines against viruses that cause acute self-limited infections
|
||
|
|
||
|
32:39.000 --> 32:46.000
|
||
|
that's mostly been done by making either an attenuated or killed virus
|
||
|
|
||
|
32:47.000 --> 32:59.000
|
||
|
which induces an immune response that mimics the immune response that you get to the natural infection because the natural infection will give you lifelong or at least long lasting immunity
|
||
|
|
||
|
33:00.000 --> 33:06.000
|
||
|
but now what's left are viruses that cause chronic infections or cancer that causes chronic disease
|
||
|
|
||
|
33:07.000 --> 33:13.000
|
||
|
where the disease itself does not induce an adequate response to get protection
|
||
|
|
||
|
33:13.000 --> 33:18.000
|
||
|
so now the vaccine has to be better than the virus or the cancer itself
|
||
|
|
||
|
33:19.000 --> 33:22.000
|
||
|
so we have to develop new ways again
|
||
|
|
||
|
33:23.000 --> 33:26.000
|
||
|
so it's very important to see how deceptive what he just said is
|
||
|
|
||
|
33:27.000 --> 33:34.000
|
||
|
and it is actually one of the best soundbite examples that I've ever found of this particular point
|
||
|
|
||
|
33:35.000 --> 33:38.000
|
||
|
which is really pervasive across this whole narrative
|
||
|
|
||
|
33:39.000 --> 33:46.000
|
||
|
the idea is that we can augment the immune system to respond to any disease
|
||
|
|
||
|
33:47.000 --> 33:49.000
|
||
|
it's the immune system we have to augment
|
||
|
|
||
|
33:50.000 --> 34:00.000
|
||
|
it can't be and therefore we use the word vaccine to describe the intent to augment the immune system
|
||
|
|
||
|
34:01.000 --> 34:05.000
|
||
|
and so what they have done is essentially cast an enchantment
|
||
|
|
||
|
34:06.000 --> 34:17.000
|
||
|
wherein the use of the word vaccine or the characterization of something as a disease implies a certain rubric of faith
|
||
|
|
||
|
34:18.000 --> 34:21.000
|
||
|
if I call it a disease that means there must be a cure
|
||
|
|
||
|
34:22.000 --> 34:25.000
|
||
|
if I call it a disease that means there might be a vaccine
|
||
|
|
||
|
34:25.000 --> 34:30.000
|
||
|
if I call it a disease you need my medicine
|
||
|
|
||
|
34:32.000 --> 34:38.000
|
||
|
now we I think this is a really important point to make even if I'm beating a dead horse here
|
||
|
|
||
|
34:38.000 --> 34:45.000
|
||
|
but it's really it's a it's a distinction that we are allowing them to blur
|
||
|
|
||
|
34:45.000 --> 34:54.000
|
||
|
where actually vaccine and this is how he said it
|
||
|
|
||
|
34:55.000 --> 34:58.000
|
||
|
traditionally vaccines were made of a weakened or a dead virus
|
||
|
|
||
|
34:59.000 --> 35:06.000
|
||
|
and it mimicked the infection well enough so that the
|
||
|
|
||
|
35:07.000 --> 35:20.000
|
||
|
immunity produced by the vaccine was equivalent to or very close to equivalent to protection from exposure to the disease or infection itself
|
||
|
|
||
|
35:21.000 --> 35:29.000
|
||
|
the immune memory that's generated by infection was very similar to the immune memory generated by the live attenuated vaccine
|
||
|
|
||
|
35:30.000 --> 35:34.000
|
||
|
but we can't make a live attenuated vaccine against cancer
|
||
|
|
||
|
35:35.000 --> 35:38.000
|
||
|
we can't make a live attenuated vaccine against a genetic disorder
|
||
|
|
||
|
35:39.000 --> 35:43.000
|
||
|
we can't make a live attenuated vaccine against diabetes
|
||
|
|
||
|
35:45.000 --> 35:51.000
|
||
|
but if we call diabetes a disease now we can you know all diseases have potentially a vaccine
|
||
|
|
||
|
35:52.000 --> 35:57.000
|
||
|
it's just that this disease doesn't produce an adequate immune response
|
||
|
|
||
|
35:57.000 --> 36:06.000
|
||
|
you see he's he's suggesting something based on an assumption that is not biologically proven
|
||
|
|
||
|
36:07.000 --> 36:14.000
|
||
|
that cancer for example is always caused by viruses so because cancer is a disease caused by a pathogen
|
||
|
|
||
|
36:14.000 --> 36:21.000
|
||
|
and you are the host then you need a vaccine to prevent that pathogen from causing disease in you
|
||
|
|
||
|
36:22.000 --> 36:30.000
|
||
|
but it's a surprisingly small number of cancers which are associated directly with causally to a virus
|
||
|
|
||
|
36:33.000 --> 36:42.000
|
||
|
and when we try to make a vaccine against a cancer we're actually trying to point T cell memory at a protein which is unique for the cancer
|
||
|
|
||
|
36:43.000 --> 36:53.000
|
||
|
it's not a failure of the immune system so much as usually a camouflage of the cancer because the cancer is made of self cells
|
||
|
|
||
|
36:54.000 --> 36:56.000
|
||
|
so the immune system can't really see it
|
||
|
|
||
|
36:58.000 --> 37:05.000
|
||
|
so this is a very deceptive language bait and switch that has been going on for decades that they have been working for decades
|
||
|
|
||
|
37:06.000 --> 37:13.000
|
||
|
and it probably all goes all the way back to as far as Robert Gallo and Murray Gardner
|
||
|
|
||
|
37:13.000 --> 37:22.000
|
||
|
and all of these people like David Baltimore who were involved in the early stages of HIV retroviruses
|
||
|
|
||
|
37:22.000 --> 37:28.000
|
||
|
and cancer causing viruses in this whole theory of what viruses do
|
||
|
|
||
|
37:29.000 --> 37:42.000
|
||
|
and so what I'm suggesting to you is that this mythology was purposefully created over many decades
|
||
|
|
||
|
37:43.000 --> 37:50.000
|
||
|
so that the public health exercise that we've been through for the last three years was possible
|
||
|
|
||
|
37:51.000 --> 37:59.000
|
||
|
and they almost, this almost was derailed, it was almost derailed once on 9-11
|
||
|
|
||
|
38:00.000 --> 38:08.000
|
||
|
and you'll have to watch Usatonic Live and look at his long catalogue of this to understand what I'm suggesting here
|
||
|
|
||
|
38:08.000 --> 38:16.000
|
||
|
but it could be that 9-11 was supposed to be a biological attack and somehow or another it ended up to be just a terrorist attack
|
||
|
|
||
|
38:21.000 --> 38:31.000
|
||
|
and anyway the point is that we have been on a long progression, a long plan to controlled demolish America
|
||
|
|
||
|
38:32.000 --> 38:42.000
|
||
|
and I think David Griffin could also tell us a lot about the financial aspects of this controlled demolition of the American system
|
||
|
|
||
|
38:42.000 --> 38:48.000
|
||
|
and the freedom that it represents, the Constitution itself is going to be under assault
|
||
|
|
||
|
38:49.000 --> 38:54.000
|
||
|
once the financial and societal fabric starts to rip
|
||
|
|
||
|
38:55.000 --> 38:59.000
|
||
|
and if we want to address this problem it's going to have to rip
|
||
|
|
||
|
38:59.000 --> 39:04.000
|
||
|
we're going to have to come together as a country in a different way than we are now
|
||
|
|
||
|
39:04.000 --> 39:07.000
|
||
|
and love our neighbors in a way that we are not doing now
|
||
|
|
||
|
39:07.000 --> 39:13.000
|
||
|
in order for America to make it through on the other side as America in some new form
|
||
|
|
||
|
39:14.000 --> 39:18.000
|
||
|
based on truth and justice and the American way
|
||
|
|
||
|
39:19.000 --> 39:21.000
|
||
|
whatever that used to be
|
||
|
|
||
|
39:22.000 --> 39:27.000
|
||
|
so vaccination is a methodology that will work as a methodology, excuse me, that will work on everything
|
||
|
|
||
|
39:27.000 --> 39:29.000
|
||
|
and that's the argument that he's making now
|
||
|
|
||
|
39:30.000 --> 39:40.000
|
||
|
he's making it with the words that he wants to use in order so that we transfer the value of vaccination to as much disease as possible
|
||
|
|
||
|
39:41.000 --> 39:44.000
|
||
|
in fact he is exercising this enchantment of
|
||
|
|
||
|
39:45.000 --> 39:50.000
|
||
|
if I say disease, you say cure, disease, cure, disease, cure
|
||
|
|
||
|
39:50.000 --> 39:55.000
|
||
|
if I say disease, you say vaccine, vaccine, disease, disease, vaccine
|
||
|
|
||
|
39:57.000 --> 39:58.000
|
||
|
it's an enchantment
|
||
|
|
||
|
39:59.000 --> 40:02.000
|
||
|
and he might only be reciting it because he's under this enchantment
|
||
|
|
||
|
40:03.000 --> 40:05.000
|
||
|
but I think that at a certain moment
|
||
|
|
||
|
40:05.000 --> 40:09.000
|
||
|
you as an academic and academic magician
|
||
|
|
||
|
40:09.000 --> 40:15.000
|
||
|
you become smart enough to know that this sales pitch is that what it is, it's a sales pitch
|
||
|
|
||
|
40:15.000 --> 40:19.000
|
||
|
and if you're making a sales pitch about vaccines it's a little different
|
||
|
|
||
|
40:19.000 --> 40:25.000
|
||
|
than making a sales pitch about your little niche research that you know isn't going to save the world
|
||
|
|
||
|
40:25.000 --> 40:30.000
|
||
|
but it's really important for you to study the pigmentation
|
||
|
|
||
|
40:30.000 --> 40:39.000
|
||
|
and chemical steps in the chloroplast function in a particular diatom
|
||
|
|
||
|
40:39.000 --> 40:41.000
|
||
|
and you know that that's not really important
|
||
|
|
||
|
40:41.000 --> 40:45.000
|
||
|
but you talk it really up in your introduction
|
||
|
|
||
|
40:45.000 --> 40:49.000
|
||
|
and when you're interviewing for a faculty job
|
||
|
|
||
|
40:50.000 --> 40:52.000
|
||
|
but that's your passion, that's your biology
|
||
|
|
||
|
40:52.000 --> 40:54.000
|
||
|
and so you exaggerate a little bit
|
||
|
|
||
|
40:54.000 --> 40:56.000
|
||
|
you know these diatoms are found all around the oceans
|
||
|
|
||
|
40:56.000 --> 40:59.000
|
||
|
and they're important in every ecosystem that has salt water
|
||
|
|
||
|
40:59.000 --> 41:04.000
|
||
|
and they're responsible for converting more than you know gigatons of carbon every year
|
||
|
|
||
|
41:04.000 --> 41:07.000
|
||
|
but nobody cares about diatoms
|
||
|
|
||
|
41:09.000 --> 41:11.000
|
||
|
but you're not selling anything
|
||
|
|
||
|
41:11.000 --> 41:15.000
|
||
|
you're not misleading the young into believing something that's not true
|
||
|
|
||
|
41:16.000 --> 41:21.000
|
||
|
you're not contributing to the governance of an entire society by lies
|
||
|
|
||
|
41:21.000 --> 41:23.000
|
||
|
you're just really enthusiastic about your biology
|
||
|
|
||
|
41:23.000 --> 41:28.000
|
||
|
and you want people to understand how important it is to the collective whole
|
||
|
|
||
|
41:30.000 --> 41:34.000
|
||
|
but when you're a biologist who's saying something like this guy saying
|
||
|
|
||
|
41:34.000 --> 41:38.000
|
||
|
you've got to know that this is a sales pitch of BS
|
||
|
|
||
|
41:38.000 --> 41:50.000
|
||
|
that is doing an end around the traditional idea of how a drug or a pharmaceutical is brought to market safely
|
||
|
|
||
|
41:51.000 --> 41:56.000
|
||
|
and that your intention is to inject anything you want intramuscularly
|
||
|
|
||
|
41:56.000 --> 42:01.000
|
||
|
with the intent of augmenting the immune system with no responsibility for when it goes wrong
|
||
|
|
||
|
42:01.000 --> 42:05.000
|
||
|
and you know that the only way that you can get away with doing this
|
||
|
|
||
|
42:05.000 --> 42:09.000
|
||
|
and have a hope of making something of this genetic technology work
|
||
|
|
||
|
42:09.000 --> 42:12.000
|
||
|
is if you get people to allow you to do it
|
||
|
|
||
|
42:16.000 --> 42:20.000
|
||
|
not everybody in this machine knows exactly how bad it is
|
||
|
|
||
|
42:20.000 --> 42:23.000
|
||
|
but everybody in this machine knows exactly that it's bad
|
||
|
|
||
|
42:23.000 --> 42:25.000
|
||
|
that it's lies
|
||
|
|
||
|
42:25.000 --> 42:27.000
|
||
|
that it's gross exaggerations
|
||
|
|
||
|
42:27.000 --> 42:31.000
|
||
|
that there are thousands and billions and millions and billions of dollars
|
||
|
|
||
|
42:31.000 --> 42:33.000
|
||
|
exchanging hands
|
||
|
|
||
|
42:33.000 --> 42:36.000
|
||
|
based on these exaggerations
|
||
|
|
||
|
42:36.000 --> 42:38.000
|
||
|
these oversimplifications
|
||
|
|
||
|
42:40.000 --> 42:42.000
|
||
|
and so he can look into the camera
|
||
|
|
||
|
42:42.000 --> 42:45.000
|
||
|
and with his fancy pink lanyardon with his sudon
|
||
|
|
||
|
42:45.000 --> 42:47.000
|
||
|
with his NIH job
|
||
|
|
||
|
42:47.000 --> 42:50.000
|
||
|
and talk all this stuff with these words
|
||
|
|
||
|
42:50.000 --> 42:52.000
|
||
|
and be as imprecise as he wants to
|
||
|
|
||
|
42:52.000 --> 42:55.000
|
||
|
knowing full well that what he is doing is casting an enchantment
|
||
|
|
||
|
42:55.000 --> 42:59.000
|
||
|
he is enchanting everyone in the future
|
||
|
|
||
|
42:59.000 --> 43:02.000
|
||
|
as part of this illusion of consensus
|
||
|
|
||
|
43:02.000 --> 43:05.000
|
||
|
that these are diseases and all diseases have cures
|
||
|
|
||
|
43:05.000 --> 43:08.000
|
||
|
and the best cures are vaccines
|
||
|
|
||
|
43:08.000 --> 43:12.000
|
||
|
it's a really simple enchantment
|
||
|
|
||
|
43:12.000 --> 43:15.000
|
||
|
all these things are diseases
|
||
|
|
||
|
43:15.000 --> 43:19.000
|
||
|
diseases have cures and cures the best ones we have are vaccines
|
||
|
|
||
|
43:19.000 --> 43:21.000
|
||
|
so I work on vaccines
|
||
|
|
||
|
43:25.000 --> 43:29.000
|
||
|
chronic infections like HIV or hepatitis C for example
|
||
|
|
||
|
43:29.000 --> 43:34.000
|
||
|
and I think more and more strategies are being developed to target those
|
||
|
|
||
|
43:34.000 --> 43:38.000
|
||
|
very similar to the ones I just talked about for cancer vaccines
|
||
|
|
||
|
43:38.000 --> 43:41.000
|
||
|
and I think hopefully within the next 5 to 10 years
|
||
|
|
||
|
43:41.000 --> 43:44.000
|
||
|
we will have vaccines for those diseases
|
||
|
|
||
|
43:44.000 --> 43:47.000
|
||
|
but of course at this point that's hope
|
||
|
|
||
|
43:47.000 --> 43:51.000
|
||
|
that's not nothing guaranteed, not promised
|
||
|
|
||
|
43:51.000 --> 43:53.000
|
||
|
I think one is
|
||
|
|
||
|
43:55.000 --> 43:59.000
|
||
|
and it's very similar to saying that this diagram means nothing
|
||
|
|
||
|
43:59.000 --> 44:04.000
|
||
|
that we can effectively ignore this diagram
|
||
|
|
||
|
44:04.000 --> 44:08.000
|
||
|
just like we can ignore any possible safety signals in
|
||
|
|
||
|
44:08.000 --> 44:10.000
|
||
|
transfection and healthy children
|
||
|
|
||
|
44:10.000 --> 44:13.000
|
||
|
we can ignore this diagram
|
||
|
|
||
|
44:13.000 --> 44:16.000
|
||
|
and we can also ignore these people
|
||
|
|
||
|
44:16.000 --> 44:18.000
|
||
|
right?
|
||
|
|
||
|
44:18.000 --> 44:21.000
|
||
|
we can ignore these people
|
||
|
|
||
|
44:21.000 --> 44:24.000
|
||
|
I have a lot of people that made graphics
|
||
|
|
||
|
44:24.000 --> 44:26.000
|
||
|
designs for the trailer
|
||
|
|
||
|
44:26.000 --> 44:29.000
|
||
|
from all over Canada and Australia
|
||
|
|
||
|
44:29.000 --> 44:31.000
|
||
|
but it was just about junior
|
||
|
|
||
|
44:31.000 --> 44:34.000
|
||
|
I said no this trailer is not about just junior
|
||
|
|
||
|
44:34.000 --> 44:37.000
|
||
|
I said it's about junior and all the vaccine injured
|
||
|
|
||
|
44:37.000 --> 44:40.000
|
||
|
that we have because there's thousands of it
|
||
|
|
||
|
44:40.000 --> 44:43.000
|
||
|
people look at the trailer and they'll tell me
|
||
|
|
||
|
44:43.000 --> 44:45.000
|
||
|
that's a lot of people I said no it's not
|
||
|
|
||
|
44:45.000 --> 44:47.000
|
||
|
that's not even a little bit
|
||
|
|
||
|
44:47.000 --> 44:48.000
|
||
|
I said there's more
|
||
|
|
||
|
44:48.000 --> 44:50.000
|
||
|
I said I would need 18 wheelers
|
||
|
|
||
|
44:50.000 --> 44:52.000
|
||
|
to put everyone's picture on it
|
||
|
|
||
|
44:52.000 --> 44:54.000
|
||
|
that thing is
|
||
|
|
||
|
44:54.000 --> 44:56.000
|
||
|
I don't want to make the pictures too small
|
||
|
|
||
|
44:56.000 --> 44:58.000
|
||
|
I want people to actually be able to see the faces
|
||
|
|
||
|
44:58.000 --> 45:00.000
|
||
|
of each person that's on here
|
||
|
|
||
|
45:00.000 --> 45:02.000
|
||
|
my whole mission now
|
||
|
|
||
|
45:02.000 --> 45:05.000
|
||
|
you know bring awareness to all the families
|
||
|
|
||
|
45:05.000 --> 45:07.000
|
||
|
because I don't want to get any emails
|
||
|
|
||
|
45:07.000 --> 45:09.000
|
||
|
text messages anymore
|
||
|
|
||
|
45:09.000 --> 45:11.000
|
||
|
I get them from all over the world
|
||
|
|
||
|
45:11.000 --> 45:13.000
|
||
|
I don't need to be proud of it
|
||
|
|
||
|
45:13.000 --> 45:15.000
|
||
|
juniorsguardianvoices.com
|
||
|
|
||
|
45:15.000 --> 45:17.000
|
||
|
and juniorsguardianvoices.com
|
||
|
|
||
|
45:17.000 --> 45:19.000
|
||
|
I walked to that side door
|
||
|
|
||
|
45:19.000 --> 45:21.000
|
||
|
I was sitting up in a
|
||
|
|
||
|
45:21.000 --> 45:23.000
|
||
|
it was like a life-size picture
|
||
|
|
||
|
45:23.000 --> 45:25.000
|
||
|
and I started crying because I could almost
|
||
|
|
||
|
45:25.000 --> 45:27.000
|
||
|
feel like I could hug them
|
||
|
|
||
|
45:27.000 --> 45:30.000
|
||
|
and I was thinking I'd be proud of it
|
||
|
|
||
|
45:35.000 --> 45:37.000
|
||
|
if I don't do what I'm doing
|
||
|
|
||
|
45:37.000 --> 45:39.000
|
||
|
I can hear them telling me
|
||
|
|
||
|
45:39.000 --> 45:41.000
|
||
|
you know you need to practice what you preach
|
||
|
|
||
|
45:41.000 --> 45:43.000
|
||
|
so that's why I have to keep doing this
|
||
|
|
||
|
45:43.000 --> 45:45.000
|
||
|
thanks for putting that link in there
|
||
|
|
||
|
45:45.000 --> 45:47.000
|
||
|
well it's about the first year
|
||
|
|
||
|
45:47.000 --> 45:48.000
|
||
|
I was ready to give up
|
||
|
|
||
|
45:48.000 --> 45:50.000
|
||
|
I didn't think I was accomplishing anything
|
||
|
|
||
|
45:50.000 --> 45:52.000
|
||
|
I didn't think it was getting out there
|
||
|
|
||
|
45:52.000 --> 45:55.000
|
||
|
and for some reason I was going through my file box
|
||
|
|
||
|
45:55.000 --> 45:57.000
|
||
|
and I found a father state card
|
||
|
|
||
|
45:57.000 --> 45:59.000
|
||
|
the last of my last father state card
|
||
|
|
||
|
45:59.000 --> 46:02.000
|
||
|
and now I just started crying
|
||
|
|
||
|
46:02.000 --> 46:05.000
|
||
|
for probably about three or four hours on the couch
|
||
|
|
||
|
46:05.000 --> 46:08.000
|
||
|
I figured that was his way of telling me to
|
||
|
|
||
|
46:08.000 --> 46:10.000
|
||
|
don't give up
|
||
|
|
||
|
46:10.000 --> 46:12.000
|
||
|
to keep up fighting
|
||
|
|
||
|
46:12.000 --> 46:14.000
|
||
|
and that's the same one I have on the back of my motorcycle
|
||
|
|
||
|
46:14.000 --> 46:16.000
|
||
|
I figured well
|
||
|
|
||
|
46:16.000 --> 46:18.000
|
||
|
I found it
|
||
|
|
||
|
46:18.000 --> 46:20.000
|
||
|
I got to put it on my bike
|
||
|
|
||
|
46:20.000 --> 46:22.000
|
||
|
to remind me why I'm doing this
|
||
|
|
||
|
46:22.000 --> 46:24.000
|
||
|
he cried when he talked about his son
|
||
|
|
||
|
46:24.000 --> 46:26.000
|
||
|
because you don't lose his son
|
||
|
|
||
|
46:26.000 --> 46:28.000
|
||
|
and stop crying about it
|
||
|
|
||
|
46:28.000 --> 46:30.000
|
||
|
I can cry about it
|
||
|
|
||
|
46:30.000 --> 46:32.000
|
||
|
I don't have a loss to son
|
||
|
|
||
|
46:32.000 --> 46:34.000
|
||
|
I just have them
|
||
|
|
||
|
46:34.000 --> 46:36.000
|
||
|
you only have to have them to know
|
||
|
|
||
|
46:36.000 --> 46:38.000
|
||
|
that this guy might possibly be feeling
|
||
|
|
||
|
46:38.000 --> 46:44.000
|
||
|
and I show this video
|
||
|
|
||
|
46:44.000 --> 46:46.000
|
||
|
not only because I want you to know about his website
|
||
|
|
||
|
46:46.000 --> 46:48.000
|
||
|
but I really want you to see
|
||
|
|
||
|
46:48.000 --> 46:52.000
|
||
|
that this guy is organized around everybody
|
||
|
|
||
|
46:52.000 --> 46:55.000
|
||
|
he wants all these peoples justice
|
||
|
|
||
|
46:55.000 --> 46:57.000
|
||
|
and I think we need to really
|
||
|
|
||
|
46:57.000 --> 46:59.000
|
||
|
start to think this way
|
||
|
|
||
|
46:59.000 --> 47:02.000
|
||
|
that in order for this to work
|
||
|
|
||
|
47:02.000 --> 47:04.000
|
||
|
we've all got to come together
|
||
|
|
||
|
47:04.000 --> 47:06.000
|
||
|
at juniorsguardianvoice.com
|
||
|
|
||
|
47:06.000 --> 47:08.000
|
||
|
then we've got to come together there
|
||
|
|
||
|
47:08.000 --> 47:12.000
|
||
|
but we've got to find ways
|
||
|
|
||
|
47:12.000 --> 47:14.000
|
||
|
to make sure that everybody
|
||
|
|
||
|
47:14.000 --> 47:16.000
|
||
|
who was injured by this
|
||
|
|
||
|
47:16.000 --> 47:18.000
|
||
|
transfection and transformation
|
||
|
|
||
|
47:18.000 --> 47:20.000
|
||
|
roll out
|
||
|
|
||
|
47:20.000 --> 47:22.000
|
||
|
nowhere to report
|
||
|
|
||
|
47:22.000 --> 47:24.000
|
||
|
their injuries and that they do it
|
||
|
|
||
|
47:24.000 --> 47:26.000
|
||
|
that everyone who lost someone
|
||
|
|
||
|
47:26.000 --> 47:28.000
|
||
|
to transfection and transformation
|
||
|
|
||
|
47:28.000 --> 47:30.000
|
||
|
is
|
||
|
|
||
|
47:30.000 --> 47:32.000
|
||
|
bringing these numbers to account
|
||
|
|
||
|
47:32.000 --> 47:34.000
|
||
|
because there are people who probably
|
||
|
|
||
|
47:34.000 --> 47:36.000
|
||
|
need to reflect again
|
||
|
|
||
|
47:36.000 --> 47:38.000
|
||
|
ok when did grandma die
|
||
|
|
||
|
47:38.000 --> 47:40.000
|
||
|
when did she die
|
||
|
|
||
|
47:40.000 --> 47:42.000
|
||
|
and what did they say she died of
|
||
|
|
||
|
47:42.000 --> 47:44.000
|
||
|
there are a lot of people
|
||
|
|
||
|
47:44.000 --> 47:46.000
|
||
|
who haven't asked that question yet
|
||
|
|
||
|
47:46.000 --> 47:48.000
|
||
|
there are a lot of people
|
||
|
|
||
|
47:48.000 --> 47:50.000
|
||
|
who haven't asked that question yet
|
||
|
|
||
|
47:50.000 --> 47:54.000
|
||
|
that had people die in the hospital
|
||
|
|
||
|
47:54.000 --> 47:56.000
|
||
|
who haven't asked that question yet
|
||
|
|
||
|
47:56.000 --> 48:00.000
|
||
|
that might need to ask the protocol question
|
||
|
|
||
|
48:00.000 --> 48:04.000
|
||
|
we've got a lot of work to do ladies and gentlemen
|
||
|
|
||
|
48:04.000 --> 48:06.000
|
||
|
because this illusion of consensus
|
||
|
|
||
|
48:06.000 --> 48:08.000
|
||
|
is not going away
|
||
|
|
||
|
48:08.000 --> 48:10.000
|
||
|
these players are not going away
|
||
|
|
||
|
48:10.000 --> 48:12.000
|
||
|
they won't leave us alone
|
||
|
|
||
|
48:12.000 --> 48:14.000
|
||
|
they're still here
|
||
|
|
||
|
48:14.000 --> 48:16.000
|
||
|
they've still got millions of followers
|
||
|
|
||
|
48:16.000 --> 48:18.000
|
||
|
they've still got substacks
|
||
|
|
||
|
48:18.000 --> 48:20.000
|
||
|
that earn $50,000 a week
|
||
|
|
||
|
48:20.000 --> 48:22.000
|
||
|
they're still doing podcasts
|
||
|
|
||
|
48:22.000 --> 48:24.000
|
||
|
four or five times a day
|
||
|
|
||
|
48:24.000 --> 48:26.000
|
||
|
sometimes
|
||
|
|
||
|
48:26.000 --> 48:28.000
|
||
|
these people are still traveling
|
||
|
|
||
|
48:28.000 --> 48:30.000
|
||
|
the world
|
||
|
|
||
|
48:34.000 --> 48:36.000
|
||
|
and they are still pushing this
|
||
|
|
||
|
48:36.000 --> 48:38.000
|
||
|
DNA idea
|
||
|
|
||
|
48:38.000 --> 48:40.000
|
||
|
we covered a
|
||
|
|
||
|
48:40.000 --> 48:42.000
|
||
|
really important stream
|
||
|
|
||
|
48:42.000 --> 48:44.000
|
||
|
a few days before I quit
|
||
|
|
||
|
48:44.000 --> 48:46.000
|
||
|
it was a Canadian
|
||
|
|
||
|
48:46.000 --> 48:48.000
|
||
|
children's health defense
|
||
|
|
||
|
48:48.000 --> 48:50.000
|
||
|
chapter interviewing
|
||
|
|
||
|
48:50.000 --> 48:52.000
|
||
|
the hero from Canada
|
||
|
|
||
|
48:52.000 --> 48:54.000
|
||
|
Byron brittle
|
||
|
|
||
|
48:54.000 --> 48:56.000
|
||
|
who had his
|
||
|
|
||
|
48:56.000 --> 48:58.000
|
||
|
career basically destroyed
|
||
|
|
||
|
48:58.000 --> 49:00.000
|
||
|
because he found a document
|
||
|
|
||
|
49:00.000 --> 49:02.000
|
||
|
from the Japanese Pfizer
|
||
|
|
||
|
49:02.000 --> 49:04.000
|
||
|
trials showing
|
||
|
|
||
|
49:04.000 --> 49:06.000
|
||
|
or the Japanese
|
||
|
|
||
|
49:06.000 --> 49:08.000
|
||
|
paperwork submitted
|
||
|
|
||
|
49:08.000 --> 49:10.000
|
||
|
by Pfizer
|
||
|
|
||
|
49:10.000 --> 49:12.000
|
||
|
I'm showing that the
|
||
|
|
||
|
49:12.000 --> 49:14.000
|
||
|
the transfection agent
|
||
|
|
||
|
49:14.000 --> 49:16.000
|
||
|
and if you
|
||
|
|
||
|
49:16.000 --> 49:18.000
|
||
|
transfected luciferase in this case
|
||
|
|
||
|
49:18.000 --> 49:20.000
|
||
|
they could see glow-in-the-dark protein
|
||
|
|
||
|
49:20.000 --> 49:22.000
|
||
|
all around the body
|
||
|
|
||
|
49:22.000 --> 49:24.000
|
||
|
and it didn't stay in the muscle
|
||
|
|
||
|
49:24.000 --> 49:26.000
|
||
|
and he reported this very early
|
||
|
|
||
|
49:26.000 --> 49:28.000
|
||
|
and really really really
|
||
|
|
||
|
49:28.000 --> 49:30.000
|
||
|
suffered for it
|
||
|
|
||
|
49:30.000 --> 49:32.000
|
||
|
and two years later
|
||
|
|
||
|
49:32.000 --> 49:34.000
|
||
|
we have the inventor
|
||
|
|
||
|
49:34.000 --> 49:36.000
|
||
|
of the lipid nanoparticle technology
|
||
|
|
||
|
49:36.000 --> 49:38.000
|
||
|
Peter Kullis
|
||
|
|
||
|
49:38.000 --> 49:40.000
|
||
|
giving a celebratory lecture
|
||
|
|
||
|
49:40.000 --> 49:42.000
|
||
|
regarding the garden near prize
|
||
|
|
||
|
49:42.000 --> 49:44.000
|
||
|
in Canada
|
||
|
|
||
|
49:44.000 --> 49:46.000
|
||
|
a sort of pre-noble prize
|
||
|
|
||
|
49:46.000 --> 49:48.000
|
||
|
where he just casually answers questions
|
||
|
|
||
|
49:48.000 --> 49:50.000
|
||
|
at the end where he says
|
||
|
|
||
|
49:50.000 --> 49:52.000
|
||
|
yeah I ruined the career
|
||
|
|
||
|
49:52.000 --> 49:54.000
|
||
|
or burnt out five postdocs
|
||
|
|
||
|
49:54.000 --> 49:56.000
|
||
|
trying to figure out
|
||
|
|
||
|
49:56.000 --> 49:58.000
|
||
|
how to target these lipids
|
||
|
|
||
|
49:58.000 --> 50:00.000
|
||
|
to particular places in the body
|
||
|
|
||
|
50:00.000 --> 50:02.000
|
||
|
and we never succeeded
|
||
|
|
||
|
50:02.000 --> 50:06.000
|
||
|
or at least 20 years away from figuring that out
|
||
|
|
||
|
50:06.000 --> 50:08.000
|
||
|
but of course the one of the
|
||
|
|
||
|
50:08.000 --> 50:10.000
|
||
|
primary assumptions of
|
||
|
|
||
|
50:10.000 --> 50:12.000
|
||
|
the effectiveness of the vaccine
|
||
|
|
||
|
50:12.000 --> 50:14.000
|
||
|
was that it stayed in the muscle
|
||
|
|
||
|
50:14.000 --> 50:16.000
|
||
|
and that the expression
|
||
|
|
||
|
50:16.000 --> 50:18.000
|
||
|
of the spike protein was
|
||
|
|
||
|
50:18.000 --> 50:20.000
|
||
|
extremely temporary
|
||
|
|
||
|
50:20.000 --> 50:22.000
|
||
|
and limited
|
||
|
|
||
|
50:22.000 --> 50:24.000
|
||
|
but we know from their discussions
|
||
|
|
||
|
50:24.000 --> 50:26.000
|
||
|
and their descriptions of their own work
|
||
|
|
||
|
50:26.000 --> 50:28.000
|
||
|
that they optimized it for
|
||
|
|
||
|
50:28.000 --> 50:30.000
|
||
|
maximum lifetime
|
||
|
|
||
|
50:30.000 --> 50:32.000
|
||
|
and maximum protein production
|
||
|
|
||
|
50:36.000 --> 50:38.000
|
||
|
we really really really
|
||
|
|
||
|
50:38.000 --> 50:40.000
|
||
|
need to understand that it's not
|
||
|
|
||
|
50:40.000 --> 50:42.000
|
||
|
a matter of
|
||
|
|
||
|
50:42.000 --> 50:44.000
|
||
|
what's true that counts anymore
|
||
|
|
||
|
50:44.000 --> 50:46.000
|
||
|
but it's a matter of what is perceived to be true
|
||
|
|
||
|
50:46.000 --> 50:48.000
|
||
|
and that these people have been
|
||
|
|
||
|
50:48.000 --> 50:50.000
|
||
|
actively trying to
|
||
|
|
||
|
50:50.000 --> 50:52.000
|
||
|
not let us understand
|
||
|
|
||
|
50:52.000 --> 50:54.000
|
||
|
what is really true
|
||
|
|
||
|
50:54.000 --> 50:56.000
|
||
|
and about the transfection
|
||
|
|
||
|
50:56.000 --> 50:58.000
|
||
|
it must be understood
|
||
|
|
||
|
50:58.000 --> 51:00.000
|
||
|
I think that somebody like
|
||
|
|
||
|
51:00.000 --> 51:02.000
|
||
|
Sukhid Bhakti and I'm sure that my friend
|
||
|
|
||
|
51:02.000 --> 51:04.000
|
||
|
Mike Eden would also agree with me
|
||
|
|
||
|
51:04.000 --> 51:06.000
|
||
|
when I say the transfection
|
||
|
|
||
|
51:06.000 --> 51:08.000
|
||
|
in its purest form
|
||
|
|
||
|
51:08.000 --> 51:10.000
|
||
|
is wholly inappropriate for
|
||
|
|
||
|
51:10.000 --> 51:12.000
|
||
|
healthy humans
|
||
|
|
||
|
51:12.000 --> 51:14.000
|
||
|
in its purest form
|
||
|
|
||
|
51:14.000 --> 51:16.000
|
||
|
the best case scenario
|
||
|
|
||
|
51:16.000 --> 51:18.000
|
||
|
you know the
|
||
|
|
||
|
51:18.000 --> 51:20.000
|
||
|
the coffee artist
|
||
|
|
||
|
51:20.000 --> 51:22.000
|
||
|
cappuccino the best
|
||
|
|
||
|
51:22.000 --> 51:24.000
|
||
|
whatever you got
|
||
|
|
||
|
51:24.000 --> 51:26.000
|
||
|
it's wholly inappropriate for healthy humans
|
||
|
|
||
|
51:26.000 --> 51:28.000
|
||
|
it didn't get any good form
|
||
|
|
||
|
51:28.000 --> 51:30.000
|
||
|
it's not going to be good form
|
||
|
|
||
|
51:30.000 --> 51:32.000
|
||
|
it's definitely not going to be able to augment their immune system
|
||
|
|
||
|
51:32.000 --> 51:34.000
|
||
|
now upscaling
|
||
|
|
||
|
51:34.000 --> 51:36.000
|
||
|
from this beautiful perfect
|
||
|
|
||
|
51:36.000 --> 51:38.000
|
||
|
purest form
|
||
|
|
||
|
51:38.000 --> 51:40.000
|
||
|
of
|
||
|
|
||
|
51:40.000 --> 51:42.000
|
||
|
transfection to
|
||
|
|
||
|
51:42.000 --> 51:44.000
|
||
|
from nanograms to kilograms
|
||
|
|
||
|
51:45.000 --> 51:47.000
|
||
|
introduced a whole host
|
||
|
|
||
|
51:47.000 --> 51:48.000
|
||
|
of
|
||
|
|
||
|
51:48.000 --> 51:50.000
|
||
|
quality control and production problems
|
||
|
|
||
|
51:50.000 --> 51:52.000
|
||
|
that have never been adequately
|
||
|
|
||
|
51:52.000 --> 51:54.000
|
||
|
explored as being conquered
|
||
|
|
||
|
51:54.000 --> 51:56.000
|
||
|
you know have they really solved
|
||
|
|
||
|
51:56.000 --> 51:58.000
|
||
|
all these problems or do they just go
|
||
|
|
||
|
51:58.000 --> 52:00.000
|
||
|
from making one
|
||
|
|
||
|
52:00.000 --> 52:02.000
|
||
|
good
|
||
|
|
||
|
52:02.000 --> 52:04.000
|
||
|
grandma's apple pie
|
||
|
|
||
|
52:04.000 --> 52:06.000
|
||
|
to 10,000 a day
|
||
|
|
||
|
52:06.000 --> 52:08.000
|
||
|
and just tell us that these pies
|
||
|
|
||
|
52:08.000 --> 52:10.000
|
||
|
are as good as the one that your grandma made
|
||
|
|
||
|
52:10.000 --> 52:12.000
|
||
|
because
|
||
|
|
||
|
52:12.000 --> 52:14.000
|
||
|
when your grandma makes a pie it is
|
||
|
|
||
|
52:14.000 --> 52:16.000
|
||
|
the purest form
|
||
|
|
||
|
52:16.000 --> 52:20.000
|
||
|
of transfection and it's a tasty pie
|
||
|
|
||
|
52:20.000 --> 52:22.000
|
||
|
but you can't call that apple pie
|
||
|
|
||
|
52:22.000 --> 52:24.000
|
||
|
a something that you can live on
|
||
|
|
||
|
52:24.000 --> 52:26.000
|
||
|
it's not a nutritious meal
|
||
|
|
||
|
52:26.000 --> 52:28.000
|
||
|
it's a dessert
|
||
|
|
||
|
52:28.000 --> 52:30.000
|
||
|
and so in its purest form
|
||
|
|
||
|
52:30.000 --> 52:32.000
|
||
|
it is not a nourishing meal
|
||
|
|
||
|
52:32.000 --> 52:34.000
|
||
|
it's an apple pie
|
||
|
|
||
|
52:36.000 --> 52:38.000
|
||
|
and if you take grandma's apple pie
|
||
|
|
||
|
52:38.000 --> 52:40.000
|
||
|
and you decide okay we're going to go from making one
|
||
|
|
||
|
52:40.000 --> 52:42.000
|
||
|
to making 10,000 there are a lot of
|
||
|
|
||
|
52:42.000 --> 52:44.000
|
||
|
a
|
||
|
|
||
|
52:44.000 --> 52:46.000
|
||
|
lot of scaling up problems
|
||
|
|
||
|
52:46.000 --> 52:48.000
|
||
|
that you need to conquer
|
||
|
|
||
|
52:48.000 --> 52:50.000
|
||
|
in order to take grandma's perfect pie
|
||
|
|
||
|
52:50.000 --> 52:52.000
|
||
|
and make 10,000 of a
|
||
|
|
||
|
52:52.000 --> 52:54.000
|
||
|
a day every day consistently
|
||
|
|
||
|
52:54.000 --> 52:56.000
|
||
|
and in fact
|
||
|
|
||
|
52:56.000 --> 52:58.000
|
||
|
you can listen to Elon Musk
|
||
|
|
||
|
52:58.000 --> 53:00.000
|
||
|
on Joe Rogan
|
||
|
|
||
|
53:00.000 --> 53:02.000
|
||
|
not too long ago explaining
|
||
|
|
||
|
53:02.000 --> 53:04.000
|
||
|
that making
|
||
|
|
||
|
53:04.000 --> 53:06.000
|
||
|
a prototype of an electric car
|
||
|
|
||
|
53:06.000 --> 53:08.000
|
||
|
is actually ridiculously easy
|
||
|
|
||
|
53:08.000 --> 53:10.000
|
||
|
and the problem is a thousand
|
||
|
|
||
|
53:10.000 --> 53:12.000
|
||
|
times harder is
|
||
|
|
||
|
53:12.000 --> 53:14.000
|
||
|
to scale up production
|
||
|
|
||
|
53:14.000 --> 53:16.000
|
||
|
of the car
|
||
|
|
||
|
53:16.000 --> 53:18.000
|
||
|
occasionally Elon Musk
|
||
|
|
||
|
53:18.000 --> 53:20.000
|
||
|
says things that make sense and are
|
||
|
|
||
|
53:20.000 --> 53:22.000
|
||
|
actually almost above high school level
|
||
|
|
||
|
53:22.000 --> 53:24.000
|
||
|
intelligence and that's
|
||
|
|
||
|
53:24.000 --> 53:26.000
|
||
|
in that entire interview one of the few
|
||
|
|
||
|
53:26.000 --> 53:28.000
|
||
|
intelligent things that he said
|
||
|
|
||
|
53:28.000 --> 53:30.000
|
||
|
that didn't just make him
|
||
|
|
||
|
53:30.000 --> 53:32.000
|
||
|
sound like a clown
|
||
|
|
||
|
53:32.000 --> 53:34.000
|
||
|
he made comments about the pizza
|
||
|
|
||
|
53:34.000 --> 53:36.000
|
||
|
which was pretty good and he explained
|
||
|
|
||
|
53:36.000 --> 53:38.000
|
||
|
that making a prototype electric car
|
||
|
|
||
|
53:38.000 --> 53:40.000
|
||
|
is relatively easy
|
||
|
|
||
|
53:40.000 --> 53:42.000
|
||
|
relative to figuring out how to
|
||
|
|
||
|
53:42.000 --> 53:44.000
|
||
|
produce it
|
||
|
|
||
|
53:44.000 --> 53:46.000
|
||
|
and this scaling up
|
||
|
|
||
|
53:46.000 --> 53:48.000
|
||
|
from making
|
||
|
|
||
|
53:48.000 --> 53:50.000
|
||
|
transfection in its purest form
|
||
|
|
||
|
53:50.000 --> 53:52.000
|
||
|
to making billions of doses
|
||
|
|
||
|
53:52.000 --> 53:54.000
|
||
|
in a given three-year period
|
||
|
|
||
|
53:56.000 --> 53:58.000
|
||
|
has just been glossed over as
|
||
|
|
||
|
53:58.000 --> 54:00.000
|
||
|
yeah sure we did it
|
||
|
|
||
|
54:00.000 --> 54:02.000
|
||
|
no, no you didn't
|
||
|
|
||
|
54:02.000 --> 54:04.000
|
||
|
there's no possible way you did
|
||
|
|
||
|
54:04.000 --> 54:06.000
|
||
|
and that's what Mike Eden brought
|
||
|
|
||
|
54:06.000 --> 54:08.000
|
||
|
to the table very early on
|
||
|
|
||
|
54:08.000 --> 54:10.000
|
||
|
in this discussion
|
||
|
|
||
|
54:10.000 --> 54:12.000
|
||
|
so the R&A had to be impure
|
||
|
|
||
|
54:12.000 --> 54:14.000
|
||
|
it had to be impure
|
||
|
|
||
|
54:14.000 --> 54:16.000
|
||
|
because even when they made it in its purest form
|
||
|
|
||
|
54:16.000 --> 54:18.000
|
||
|
in the small batch
|
||
|
|
||
|
54:18.000 --> 54:20.000
|
||
|
you know
|
||
|
|
||
|
54:20.000 --> 54:22.000
|
||
|
grandma's pie scenario
|
||
|
|
||
|
54:22.000 --> 54:24.000
|
||
|
the R&A
|
||
|
|
||
|
54:24.000 --> 54:26.000
|
||
|
was still pretty
|
||
|
|
||
|
54:26.000 --> 54:28.000
|
||
|
not pure
|
||
|
|
||
|
54:28.000 --> 54:30.000
|
||
|
and now
|
||
|
|
||
|
54:30.000 --> 54:32.000
|
||
|
that they scaled it up using bacteria
|
||
|
|
||
|
54:32.000 --> 54:34.000
|
||
|
now that they scaled it up using a different process
|
||
|
|
||
|
54:34.000 --> 54:36.000
|
||
|
now that they scaled it up from
|
||
|
|
||
|
54:36.000 --> 54:38.000
|
||
|
nanograms to kilograms
|
||
|
|
||
|
54:38.000 --> 54:40.000
|
||
|
there's all kinds of impurities
|
||
|
|
||
|
54:40.000 --> 54:42.000
|
||
|
related to the R&A and unrelated to the R&A
|
||
|
|
||
|
54:42.000 --> 54:44.000
|
||
|
but related to its production
|
||
|
|
||
|
54:48.000 --> 54:50.000
|
||
|
and
|
||
|
|
||
|
54:50.000 --> 54:52.000
|
||
|
let's stay on the transfection itself
|
||
|
|
||
|
54:52.000 --> 54:54.000
|
||
|
the R&A was codon optimized
|
||
|
|
||
|
54:54.000 --> 54:56.000
|
||
|
which has a number of biological implications
|
||
|
|
||
|
54:56.000 --> 54:58.000
|
||
|
for the protein that's produced
|
||
|
|
||
|
54:58.000 --> 55:00.000
|
||
|
number one it won't be the protein
|
||
|
|
||
|
55:00.000 --> 55:02.000
|
||
|
that's produced is because
|
||
|
|
||
|
55:02.000 --> 55:04.000
|
||
|
although the codon optimization
|
||
|
|
||
|
55:04.000 --> 55:06.000
|
||
|
is changing synonymous codons
|
||
|
|
||
|
55:06.000 --> 55:08.000
|
||
|
synonymous codons are not synonymous
|
||
|
|
||
|
55:10.000 --> 55:12.000
|
||
|
and we know this because many
|
||
|
|
||
|
55:12.000 --> 55:14.000
|
||
|
genetic diseases
|
||
|
|
||
|
55:14.000 --> 55:16.000
|
||
|
seem to be
|
||
|
|
||
|
55:16.000 --> 55:18.000
|
||
|
based on silent mutations
|
||
|
|
||
|
55:18.000 --> 55:20.000
|
||
|
in the gene that they are
|
||
|
|
||
|
55:20.000 --> 55:22.000
|
||
|
correlated to
|
||
|
|
||
|
55:24.000 --> 55:26.000
|
||
|
silent mutations aren't supposed to change
|
||
|
|
||
|
55:26.000 --> 55:28.000
|
||
|
the protein but somehow silent
|
||
|
|
||
|
55:28.000 --> 55:32.000
|
||
|
mutations are linked to an awful lot of genetic diseases
|
||
|
|
||
|
55:32.000 --> 55:34.000
|
||
|
and that is likely because
|
||
|
|
||
|
55:34.000 --> 55:36.000
|
||
|
the silent mutations affect the translation
|
||
|
|
||
|
55:36.000 --> 55:38.000
|
||
|
of the protein
|
||
|
|
||
|
55:38.000 --> 55:40.000
|
||
|
the translation from R&A to protein
|
||
|
|
||
|
55:40.000 --> 55:42.000
|
||
|
requires the ribosome to do stuff
|
||
|
|
||
|
55:42.000 --> 55:44.000
|
||
|
that we don't understand
|
||
|
|
||
|
55:44.000 --> 55:46.000
|
||
|
the ribosome is a mystery machine
|
||
|
|
||
|
55:46.000 --> 55:48.000
|
||
|
the real mystery machine
|
||
|
|
||
|
55:48.000 --> 55:50.000
|
||
|
in this Scooby-Doo is the ribosome
|
||
|
|
||
|
55:50.000 --> 55:52.000
|
||
|
and
|
||
|
|
||
|
55:52.000 --> 55:54.000
|
||
|
conquering figuring out how the ribosome
|
||
|
|
||
|
55:54.000 --> 55:56.000
|
||
|
does what it does
|
||
|
|
||
|
55:56.000 --> 55:58.000
|
||
|
and how the variations in ribosomes
|
||
|
|
||
|
55:58.000 --> 56:00.000
|
||
|
change what it does
|
||
|
|
||
|
56:00.000 --> 56:02.000
|
||
|
and how the sequence of the R&A
|
||
|
|
||
|
56:02.000 --> 56:04.000
|
||
|
even with synonymous codons
|
||
|
|
||
|
56:04.000 --> 56:06.000
|
||
|
changes what the R&A does
|
||
|
|
||
|
56:06.000 --> 56:08.000
|
||
|
in the ribosome
|
||
|
|
||
|
56:08.000 --> 56:10.000
|
||
|
is a mystery
|
||
|
|
||
|
56:10.000 --> 56:12.000
|
||
|
and you might think you know what a ribosome
|
||
|
|
||
|
56:12.000 --> 56:14.000
|
||
|
is it's actually not a protein
|
||
|
|
||
|
56:14.000 --> 56:16.000
|
||
|
it's a protein
|
||
|
|
||
|
56:16.000 --> 56:18.000
|
||
|
R&A molecule hybrid
|
||
|
|
||
|
56:18.000 --> 56:20.000
|
||
|
that functionally forms this
|
||
|
|
||
|
56:20.000 --> 56:22.000
|
||
|
enzyme machine thing called a ribosome
|
||
|
|
||
|
56:22.000 --> 56:24.000
|
||
|
it's a pretty complicated thing
|
||
|
|
||
|
56:24.000 --> 56:26.000
|
||
|
that we don't really understand
|
||
|
|
||
|
56:26.000 --> 56:28.000
|
||
|
that much about
|
||
|
|
||
|
56:30.000 --> 56:32.000
|
||
|
and so when we codon optimize
|
||
|
|
||
|
56:32.000 --> 56:34.000
|
||
|
the R&A we don't know exactly what we did
|
||
|
|
||
|
56:34.000 --> 56:36.000
|
||
|
but we definitely changed how the R&A
|
||
|
|
||
|
56:36.000 --> 56:38.000
|
||
|
will translate through any
|
||
|
|
||
|
56:38.000 --> 56:40.000
|
||
|
given ribosome and any given tissue
|
||
|
|
||
|
56:40.000 --> 56:42.000
|
||
|
because
|
||
|
|
||
|
56:42.000 --> 56:44.000
|
||
|
codon optimizing changed
|
||
|
|
||
|
56:44.000 --> 56:46.000
|
||
|
the amino acid
|
||
|
|
||
|
56:46.000 --> 56:48.000
|
||
|
codons that are present
|
||
|
|
||
|
56:48.000 --> 56:50.000
|
||
|
in the viral R&A
|
||
|
|
||
|
56:50.000 --> 56:52.000
|
||
|
so it's not the same spike protein
|
||
|
|
||
|
56:52.000 --> 56:54.000
|
||
|
in addition
|
||
|
|
||
|
56:54.000 --> 56:56.000
|
||
|
because you know there's no
|
||
|
|
||
|
56:56.000 --> 56:58.000
|
||
|
bell prize technology in this stuff
|
||
|
|
||
|
56:58.000 --> 57:00.000
|
||
|
it was chemically altered
|
||
|
|
||
|
57:00.000 --> 57:02.000
|
||
|
and those chemical
|
||
|
|
||
|
57:02.000 --> 57:04.000
|
||
|
alterations can change the way
|
||
|
|
||
|
57:04.000 --> 57:06.000
|
||
|
that the ribosome interacts with the R&A
|
||
|
|
||
|
57:06.000 --> 57:08.000
|
||
|
and it can redesalt
|
||
|
|
||
|
57:08.000 --> 57:10.000
|
||
|
in premature stops
|
||
|
|
||
|
57:10.000 --> 57:12.000
|
||
|
which would shorten the protein
|
||
|
|
||
|
57:12.000 --> 57:14.000
|
||
|
and it can result
|
||
|
|
||
|
57:14.000 --> 57:16.000
|
||
|
in a wobble-based phenomenon
|
||
|
|
||
|
57:16.000 --> 57:18.000
|
||
|
which basically means that the R&A
|
||
|
|
||
|
57:18.000 --> 57:20.000
|
||
|
is not as specific
|
||
|
|
||
|
57:20.000 --> 57:22.000
|
||
|
or a particular codon as it would be
|
||
|
|
||
|
57:22.000 --> 57:24.000
|
||
|
when it has this pseudo-uridine present
|
||
|
|
||
|
57:24.000 --> 57:26.000
|
||
|
it's like a wild card
|
||
|
|
||
|
57:26.000 --> 57:28.000
|
||
|
and so now
|
||
|
|
||
|
57:28.000 --> 57:30.000
|
||
|
the ribosome can make errors of insertion
|
||
|
|
||
|
57:30.000 --> 57:32.000
|
||
|
or errors of
|
||
|
|
||
|
57:32.000 --> 57:34.000
|
||
|
substitution
|
||
|
|
||
|
57:34.000 --> 57:36.000
|
||
|
and those errors
|
||
|
|
||
|
57:36.000 --> 57:38.000
|
||
|
will necessarily have consequences
|
||
|
|
||
|
57:38.000 --> 57:40.000
|
||
|
for the antigenic properties
|
||
|
|
||
|
57:40.000 --> 57:42.000
|
||
|
of the protein
|
||
|
|
||
|
57:42.000 --> 57:44.000
|
||
|
the folding of the protein
|
||
|
|
||
|
57:44.000 --> 57:46.000
|
||
|
and potentially even the toxicity
|
||
|
|
||
|
57:46.000 --> 57:48.000
|
||
|
of it
|
||
|
|
||
|
57:49.000 --> 57:51.000
|
||
|
the worst part is these premature stops
|
||
|
|
||
|
57:51.000 --> 57:53.000
|
||
|
create very small
|
||
|
|
||
|
57:53.000 --> 57:55.000
|
||
|
R&As which small R&As
|
||
|
|
||
|
57:55.000 --> 57:57.000
|
||
|
can have the potential to interfere
|
||
|
|
||
|
57:57.000 --> 57:59.000
|
||
|
with our own endogenous R&As
|
||
|
|
||
|
57:59.000 --> 58:01.000
|
||
|
so there's all kinds of possibilities that are opened up
|
||
|
|
||
|
58:01.000 --> 58:03.000
|
||
|
by the fact that the R&As impure
|
||
|
|
||
|
58:03.000 --> 58:05.000
|
||
|
the R&A was codon optimized
|
||
|
|
||
|
58:05.000 --> 58:07.000
|
||
|
and chemically altered
|
||
|
|
||
|
58:07.000 --> 58:10.000
|
||
|
it results in all this variability
|
||
|
|
||
|
58:10.000 --> 58:12.000
|
||
|
and all of this
|
||
|
|
||
|
58:12.000 --> 58:14.000
|
||
|
extra R&A
|
||
|
|
||
|
58:14.000 --> 58:16.000
|
||
|
and extra R&As not handy
|
||
|
|
||
|
58:16.000 --> 58:19.000
|
||
|
and it's not something that we can be imprecise about
|
||
|
|
||
|
58:19.000 --> 58:21.000
|
||
|
and yet there's no doubt
|
||
|
|
||
|
58:21.000 --> 58:23.000
|
||
|
because of one and two and three
|
||
|
|
||
|
58:23.000 --> 58:26.000
|
||
|
that we are not precise here
|
||
|
|
||
|
58:26.000 --> 58:29.000
|
||
|
so the protein produced is uncharacterized
|
||
|
|
||
|
58:29.000 --> 58:33.000
|
||
|
and highly variable again because of three, four and five
|
||
|
|
||
|
58:33.000 --> 58:36.000
|
||
|
that means that the immune response
|
||
|
|
||
|
58:36.000 --> 58:39.000
|
||
|
that's being generated by this bouquet of variability
|
||
|
|
||
|
58:39.000 --> 58:41.000
|
||
|
is not very predictable either
|
||
|
|
||
|
58:42.000 --> 58:44.000
|
||
|
it's pretty predictable from the standpoint
|
||
|
|
||
|
58:44.000 --> 58:46.000
|
||
|
of when they tell you to check it this way
|
||
|
|
||
|
58:46.000 --> 58:48.000
|
||
|
yeah sure it works
|
||
|
|
||
|
58:48.000 --> 58:50.000
|
||
|
that's like saying you know
|
||
|
|
||
|
58:50.000 --> 58:52.000
|
||
|
did you use the car last night
|
||
|
|
||
|
58:52.000 --> 58:54.000
|
||
|
to your teenage daughter
|
||
|
|
||
|
58:54.000 --> 58:56.000
|
||
|
and she says no I didn't
|
||
|
|
||
|
58:56.000 --> 58:57.000
|
||
|
well what's your proof?
|
||
|
|
||
|
58:57.000 --> 58:59.000
|
||
|
well you know look in the driver's seat
|
||
|
|
||
|
58:59.000 --> 59:02.000
|
||
|
there's no Chick-fil-A
|
||
|
|
||
|
59:02.000 --> 59:05.000
|
||
|
is that proof?
|
||
|
|
||
|
59:06.000 --> 59:08.000
|
||
|
and in this case what we're talking about here
|
||
|
|
||
|
59:08.000 --> 59:11.000
|
||
|
is them saying something like well
|
||
|
|
||
|
59:11.000 --> 59:14.000
|
||
|
you know the spike protein works
|
||
|
|
||
|
59:14.000 --> 59:17.000
|
||
|
I mean when we use our own assay
|
||
|
|
||
|
59:17.000 --> 59:21.000
|
||
|
to test whether there's any spike protein produced by the M R&A
|
||
|
|
||
|
59:21.000 --> 59:24.000
|
||
|
our assay says it works great
|
||
|
|
||
|
59:24.000 --> 59:27.000
|
||
|
well if your daughter's assay
|
||
|
|
||
|
59:27.000 --> 59:29.000
|
||
|
for whether she used the car or not
|
||
|
|
||
|
59:29.000 --> 59:31.000
|
||
|
is the one that's in the car
|
||
|
|
||
|
59:31.000 --> 59:34.000
|
||
|
if your daughter's assay for whether she used the car or not
|
||
|
|
||
|
59:34.000 --> 59:36.000
|
||
|
is the one that you accept
|
||
|
|
||
|
59:36.000 --> 59:39.000
|
||
|
then she can say yeah there's no Chick-fil-A in the front seat
|
||
|
|
||
|
59:39.000 --> 59:41.000
|
||
|
so obviously I didn't use the car
|
||
|
|
||
|
59:41.000 --> 59:43.000
|
||
|
and then you got to go oh I guess you're right
|
||
|
|
||
|
59:43.000 --> 59:44.000
|
||
|
you didn't use the car
|
||
|
|
||
|
59:44.000 --> 59:46.000
|
||
|
well we used our test
|
||
|
|
||
|
59:46.000 --> 59:48.000
|
||
|
to find that spike protein is produced
|
||
|
|
||
|
59:48.000 --> 59:51.000
|
||
|
when we when we transfect cells in a dish
|
||
|
|
||
|
59:51.000 --> 59:53.000
|
||
|
so obviously it works right
|
||
|
|
||
|
59:53.000 --> 59:56.000
|
||
|
it's the same argument
|
||
|
|
||
|
59:56.000 --> 59:58.000
|
||
|
it's the same level of proof
|
||
|
|
||
|
59:59.000 --> 01:00:03.000
|
||
|
and so the LNP was never really tested in humans
|
||
|
|
||
|
01:00:03.000 --> 01:00:05.000
|
||
|
for long or short-term effects
|
||
|
|
||
|
01:00:05.000 --> 01:00:07.000
|
||
|
we just take the word of Peter Cullis
|
||
|
|
||
|
01:00:07.000 --> 01:00:08.000
|
||
|
that it works great
|
||
|
|
||
|
01:00:08.000 --> 01:00:11.000
|
||
|
but we can't really target it anywhere
|
||
|
|
||
|
01:00:11.000 --> 01:00:14.000
|
||
|
endotoxins from process two
|
||
|
|
||
|
01:00:14.000 --> 01:00:16.000
|
||
|
those are the bacteria
|
||
|
|
||
|
01:00:16.000 --> 01:00:18.000
|
||
|
and the remnants of the bacteria
|
||
|
|
||
|
01:00:18.000 --> 01:00:19.000
|
||
|
after they've been lised
|
||
|
|
||
|
01:00:19.000 --> 01:00:21.000
|
||
|
you can't clean that up very well
|
||
|
|
||
|
01:00:21.000 --> 01:00:23.000
|
||
|
and again it's compounded by the fact
|
||
|
|
||
|
01:00:23.000 --> 01:00:25.000
|
||
|
that you're not making small batch
|
||
|
|
||
|
01:00:25.000 --> 01:00:27.000
|
||
|
you're making large batch
|
||
|
|
||
|
01:00:27.000 --> 01:00:29.000
|
||
|
and in that large batch
|
||
|
|
||
|
01:00:29.000 --> 01:00:31.000
|
||
|
it's even harder to get contaminants out
|
||
|
|
||
|
01:00:31.000 --> 01:00:32.000
|
||
|
when you're rushing it out
|
||
|
|
||
|
01:00:32.000 --> 01:00:34.000
|
||
|
when you're bottling
|
||
|
|
||
|
01:00:34.000 --> 01:00:36.000
|
||
|
millions of small vials
|
||
|
|
||
|
01:00:36.000 --> 01:00:38.000
|
||
|
there's all kinds of variability
|
||
|
|
||
|
01:00:38.000 --> 01:00:40.000
|
||
|
potential there again
|
||
|
|
||
|
01:00:40.000 --> 01:00:44.000
|
||
|
these are all compounding problems
|
||
|
|
||
|
01:00:44.000 --> 01:00:47.000
|
||
|
and we still haven't really gotten
|
||
|
|
||
|
01:00:47.000 --> 01:00:49.000
|
||
|
to the double-stranded fragments
|
||
|
|
||
|
01:00:49.000 --> 01:00:51.000
|
||
|
from process one until right now
|
||
|
|
||
|
01:00:51.000 --> 01:00:53.000
|
||
|
at number nine
|
||
|
|
||
|
01:00:53.000 --> 01:00:56.000
|
||
|
and so my argument is
|
||
|
|
||
|
01:00:56.000 --> 01:00:59.000
|
||
|
hopefully I'm not too far from the microphone right now
|
||
|
|
||
|
01:00:59.000 --> 01:01:00.000
|
||
|
but the argument is
|
||
|
|
||
|
01:01:00.000 --> 01:01:02.000
|
||
|
is that number nine
|
||
|
|
||
|
01:01:02.000 --> 01:01:06.000
|
||
|
is one of many many many reasons
|
||
|
|
||
|
01:01:06.000 --> 01:01:08.000
|
||
|
to reject
|
||
|
|
||
|
01:01:08.000 --> 01:01:10.000
|
||
|
transfection in healthy humans
|
||
|
|
||
|
01:01:10.000 --> 01:01:12.000
|
||
|
the first one being
|
||
|
|
||
|
01:01:12.000 --> 01:01:14.000
|
||
|
the transfection in its purest form
|
||
|
|
||
|
01:01:14.000 --> 01:01:17.000
|
||
|
is wholly inappropriate for healthy humans
|
||
|
|
||
|
01:01:17.000 --> 01:01:19.000
|
||
|
and number one
|
||
|
|
||
|
01:01:19.000 --> 01:01:22.000
|
||
|
is the reason why they were criminally negligent
|
||
|
|
||
|
01:01:22.000 --> 01:01:24.000
|
||
|
not number nine
|
||
|
|
||
|
01:01:24.000 --> 01:01:26.000
|
||
|
they are criminally negligent
|
||
|
|
||
|
01:01:26.000 --> 01:01:28.000
|
||
|
because they have known that
|
||
|
|
||
|
01:01:28.000 --> 01:01:30.000
|
||
|
transfection in its purest form
|
||
|
|
||
|
01:01:30.000 --> 01:01:32.000
|
||
|
would be wholly inappropriate for healthy humans
|
||
|
|
||
|
01:01:32.000 --> 01:01:34.000
|
||
|
they have known that upscaling
|
||
|
|
||
|
01:01:34.000 --> 01:01:36.000
|
||
|
from nanograms to kilograms
|
||
|
|
||
|
01:01:36.000 --> 01:01:38.000
|
||
|
was going to be a disaster
|
||
|
|
||
|
01:01:38.000 --> 01:01:40.000
|
||
|
they have known that the RNA was impure
|
||
|
|
||
|
01:01:40.000 --> 01:01:42.000
|
||
|
they have known that the codon optimizing
|
||
|
|
||
|
01:01:42.000 --> 01:01:43.000
|
||
|
would cause variability
|
||
|
|
||
|
01:01:43.000 --> 01:01:44.000
|
||
|
they couldn't predict
|
||
|
|
||
|
01:01:44.000 --> 01:01:46.000
|
||
|
they have known that chemically
|
||
|
|
||
|
01:01:46.000 --> 01:01:48.000
|
||
|
altering this mRNA would cause it to last
|
||
|
|
||
|
01:01:48.000 --> 01:01:50.000
|
||
|
much longer than intended
|
||
|
|
||
|
01:01:50.000 --> 01:01:52.000
|
||
|
and could even produce small fragments of RNA
|
||
|
|
||
|
01:01:52.000 --> 01:01:55.000
|
||
|
that could interfere with our own endogenous transcripts
|
||
|
|
||
|
01:01:55.000 --> 01:01:56.000
|
||
|
they have known
|
||
|
|
||
|
01:01:56.000 --> 01:01:58.000
|
||
|
that the protein is wholly uncharacterized
|
||
|
|
||
|
01:01:58.000 --> 01:02:01.000
|
||
|
as a prodrug and should have definitely been treated as such
|
||
|
|
||
|
01:02:01.000 --> 01:02:03.000
|
||
|
they have known that the LNP
|
||
|
|
||
|
01:02:03.000 --> 01:02:06.000
|
||
|
was not tested adequately in humans
|
||
|
|
||
|
01:02:06.000 --> 01:02:09.000
|
||
|
and so the criminal negligence
|
||
|
|
||
|
01:02:09.000 --> 01:02:11.000
|
||
|
that we need to be targeting
|
||
|
|
||
|
01:02:11.000 --> 01:02:13.000
|
||
|
is not number nine
|
||
|
|
||
|
01:02:13.000 --> 01:02:15.000
|
||
|
and we are being misled
|
||
|
|
||
|
01:02:15.000 --> 01:02:17.000
|
||
|
that number nine is our opening
|
||
|
|
||
|
01:02:17.000 --> 01:02:19.000
|
||
|
number nine is our big window
|
||
|
|
||
|
01:02:19.000 --> 01:02:24.000
|
||
|
or is the spike toxic
|
||
|
|
||
|
01:02:24.000 --> 01:02:25.000
|
||
|
maybe that's our big window
|
||
|
|
||
|
01:02:25.000 --> 01:02:28.000
|
||
|
maybe we should be angry because they chose the wrong protein
|
||
|
|
||
|
01:02:28.000 --> 01:02:31.000
|
||
|
we were being told that for more than a year
|
||
|
|
||
|
01:02:31.000 --> 01:02:36.000
|
||
|
we were being told that the spike is toxic
|
||
|
|
||
|
01:02:36.000 --> 01:02:38.000
|
||
|
and that we chose the wrong protein
|
||
|
|
||
|
01:02:38.000 --> 01:02:40.000
|
||
|
for a year
|
||
|
|
||
|
01:02:40.000 --> 01:02:43.000
|
||
|
and the only reason why we are still not being told
|
||
|
|
||
|
01:02:43.000 --> 01:02:47.000
|
||
|
that very thing is because of giga ohm biological
|
||
|
|
||
|
01:02:47.000 --> 01:02:50.000
|
||
|
that's what I believe
|
||
|
|
||
|
01:02:50.000 --> 01:02:54.000
|
||
|
and so this list is important to understand
|
||
|
|
||
|
01:02:54.000 --> 01:02:57.000
|
||
|
because this is the argument that I want to make
|
||
|
|
||
|
01:02:57.000 --> 01:02:59.000
|
||
|
repeatedly over the next weeks
|
||
|
|
||
|
01:02:59.000 --> 01:03:01.000
|
||
|
until Christmas until the new year
|
||
|
|
||
|
01:03:01.000 --> 01:03:04.000
|
||
|
and I believe
|
||
|
|
||
|
01:03:04.000 --> 01:03:06.000
|
||
|
wittingly or unwittingly
|
||
|
|
||
|
01:03:06.000 --> 01:03:09.000
|
||
|
these people are involved in sustaining that
|
||
|
|
||
|
01:03:09.000 --> 01:03:11.000
|
||
|
they are involved in sustaining this
|
||
|
|
||
|
01:03:11.000 --> 01:03:13.000
|
||
|
imaginary tunnel we're in
|
||
|
|
||
|
01:03:13.000 --> 01:03:15.000
|
||
|
where there was a novel virus
|
||
|
|
||
|
01:03:15.000 --> 01:03:17.000
|
||
|
that killed millions of people
|
||
|
|
||
|
01:03:17.000 --> 01:03:21.000
|
||
|
but thank goodness we saved millions too
|
||
|
|
||
|
01:03:21.000 --> 01:03:23.000
|
||
|
and gain a function obviously is real
|
||
|
|
||
|
01:03:23.000 --> 01:03:25.000
|
||
|
because these people were lying about it
|
||
|
|
||
|
01:03:25.000 --> 01:03:27.000
|
||
|
covering it up by mean man oh man
|
||
|
|
||
|
01:03:27.000 --> 01:03:29.000
|
||
|
it's obvious now
|
||
|
|
||
|
01:03:29.000 --> 01:03:31.000
|
||
|
and so we've got to be careful because the virus
|
||
|
|
||
|
01:03:31.000 --> 01:03:34.000
|
||
|
will definitely come again
|
||
|
|
||
|
01:03:34.000 --> 01:03:37.000
|
||
|
and we cannot let our children
|
||
|
|
||
|
01:03:37.000 --> 01:03:40.000
|
||
|
grow up in this world
|
||
|
|
||
|
01:03:40.000 --> 01:03:43.000
|
||
|
but it is
|
||
|
|
||
|
01:03:43.000 --> 01:03:45.000
|
||
|
keeping the narrative alive
|
||
|
|
||
|
01:03:45.000 --> 01:03:47.000
|
||
|
the show must go on and it's not a matter of what true
|
||
|
|
||
|
01:03:47.000 --> 01:03:49.000
|
||
|
that counts it's a matter of what's perceived to be true
|
||
|
|
||
|
01:03:49.000 --> 01:03:52.000
|
||
|
so these people are still working
|
||
|
|
||
|
01:03:52.000 --> 01:03:54.000
|
||
|
Paul Offitt is still working
|
||
|
|
||
|
01:03:54.000 --> 01:03:56.000
|
||
|
and the Twiv crew is still working
|
||
|
|
||
|
01:03:56.000 --> 01:03:59.000
|
||
|
so I wanted to watch a little bit of Twiv tonight
|
||
|
|
||
|
01:03:59.000 --> 01:04:03.000
|
||
|
because I think it's fun to watch these guys
|
||
|
|
||
|
01:04:03.000 --> 01:04:06.000
|
||
|
and this episode has a number of different papers
|
||
|
|
||
|
01:04:06.000 --> 01:04:08.000
|
||
|
that they cover in it
|
||
|
|
||
|
01:04:08.000 --> 01:04:11.000
|
||
|
but the paper that I wanted to look at
|
||
|
|
||
|
01:04:11.000 --> 01:04:13.000
|
||
|
is an HPV paper
|
||
|
|
||
|
01:04:13.000 --> 01:04:15.000
|
||
|
where they look at viral prevalence
|
||
|
|
||
|
01:04:15.000 --> 01:04:19.000
|
||
|
and they make some argument about the HPV vaccine
|
||
|
|
||
|
01:04:19.000 --> 01:04:21.000
|
||
|
so I will be very honest
|
||
|
|
||
|
01:04:21.000 --> 01:04:25.000
|
||
|
I didn't know a lot about the HPV vaccine
|
||
|
|
||
|
01:04:25.000 --> 01:04:27.000
|
||
|
until I saw Vaxxed too
|
||
|
|
||
|
01:04:27.000 --> 01:04:29.000
|
||
|
and it was actually just in time
|
||
|
|
||
|
01:04:29.000 --> 01:04:31.000
|
||
|
for me not to give it to my children
|
||
|
|
||
|
01:04:31.000 --> 01:04:34.000
|
||
|
the first time that it was offered to my boys
|
||
|
|
||
|
01:04:34.000 --> 01:04:37.000
|
||
|
we were already knew not to say it
|
||
|
|
||
|
01:04:37.000 --> 01:04:39.000
|
||
|
not to take it
|
||
|
|
||
|
01:04:40.000 --> 01:04:44.000
|
||
|
but it is very disturbing to me
|
||
|
|
||
|
01:04:44.000 --> 01:04:48.000
|
||
|
that they are now pushing the HPV vaccine harder than ever
|
||
|
|
||
|
01:04:48.000 --> 01:04:53.000
|
||
|
and these kinds of disingenuous arguments are being made
|
||
|
|
||
|
01:04:53.000 --> 01:04:57.000
|
||
|
and really ridiculous statements like
|
||
|
|
||
|
01:04:57.000 --> 01:05:01.000
|
||
|
HPV vaccines are a great way to prevent cancer
|
||
|
|
||
|
01:05:01.000 --> 01:05:04.000
|
||
|
and this is just not true
|
||
|
|
||
|
01:05:04.000 --> 01:05:07.000
|
||
|
it's not proven, it's not shown, it's not measured
|
||
|
|
||
|
01:05:07.000 --> 01:05:09.000
|
||
|
it's never been observed
|
||
|
|
||
|
01:05:09.000 --> 01:05:13.000
|
||
|
and in the cases where it is purported to be observed
|
||
|
|
||
|
01:05:13.000 --> 01:05:20.000
|
||
|
great mathematical feats of ridiculousness
|
||
|
|
||
|
01:05:20.000 --> 01:05:24.000
|
||
|
are needed in order to create the illusion of a data set
|
||
|
|
||
|
01:05:24.000 --> 01:05:27.000
|
||
|
which gives the signal that they purported gives
|
||
|
|
||
|
01:05:27.000 --> 01:05:30.000
|
||
|
and that's what this Twiv is about
|
||
|
|
||
|
01:05:30.000 --> 01:05:32.000
|
||
|
is about this cell micro paper
|
||
|
|
||
|
01:05:32.000 --> 01:05:35.000
|
||
|
where they say that they looked at
|
||
|
|
||
|
01:05:35.000 --> 01:05:39.000
|
||
|
many different communities in Finland
|
||
|
|
||
|
01:05:39.000 --> 01:05:45.000
|
||
|
a total of 16,000 young people from age 18 to 22
|
||
|
|
||
|
01:05:45.000 --> 01:05:50.000
|
||
|
and they measured the prevalence of several HPV virus
|
||
|
|
||
|
01:05:50.000 --> 01:05:54.000
|
||
|
serotypes in these individuals
|
||
|
|
||
|
01:05:54.000 --> 01:05:57.000
|
||
|
four years and eight years after vaccination
|
||
|
|
||
|
01:05:57.000 --> 01:06:01.000
|
||
|
and purport to compare the vaccination schemes
|
||
|
|
||
|
01:06:01.000 --> 01:06:04.000
|
||
|
across these communities
|
||
|
|
||
|
01:06:04.000 --> 01:06:07.000
|
||
|
and the communities that they say are represented
|
||
|
|
||
|
01:06:07.000 --> 01:06:09.000
|
||
|
are an unvaccinated communities
|
||
|
|
||
|
01:06:09.000 --> 01:06:13.000
|
||
|
communities where the vaccine was targeted to girls
|
||
|
|
||
|
01:06:13.000 --> 01:06:18.000
|
||
|
and communities where the vaccine was targeted to boys and girls
|
||
|
|
||
|
01:06:18.000 --> 01:06:21.000
|
||
|
and using a general linear model
|
||
|
|
||
|
01:06:21.000 --> 01:06:26.000
|
||
|
and some other mathematical techniques to generate synthetic data
|
||
|
|
||
|
01:06:26.000 --> 01:06:31.000
|
||
|
they claim that in the
|
||
|
|
||
|
01:06:31.000 --> 01:06:35.000
|
||
|
populations where they have vaccinated both boys and girls
|
||
|
|
||
|
01:06:35.000 --> 01:06:39.000
|
||
|
they see an effect on the ecology
|
||
|
|
||
|
01:06:39.000 --> 01:06:42.000
|
||
|
of the hepatitis viruses
|
||
|
|
||
|
01:06:42.000 --> 01:06:46.000
|
||
|
that they meet in these adults
|
||
|
|
||
|
01:06:46.000 --> 01:06:49.000
|
||
|
that they are able to record in these adults
|
||
|
|
||
|
01:06:49.000 --> 01:06:53.000
|
||
|
so what we're going to watch is these four
|
||
|
|
||
|
01:06:53.000 --> 01:06:56.000
|
||
|
individuals digest this paper in real time
|
||
|
|
||
|
01:06:56.000 --> 01:06:59.000
|
||
|
they're supposed to have read it, it's supposed to be a journal club
|
||
|
|
||
|
01:06:59.000 --> 01:07:03.000
|
||
|
but in reality when you hear the absolute
|
||
|
|
||
|
01:07:03.000 --> 01:07:09.000
|
||
|
it's only can be described as shameful
|
||
|
|
||
|
01:07:09.000 --> 01:07:12.000
|
||
|
that all three of these people purport to be
|
||
|
|
||
|
01:07:12.000 --> 01:07:17.000
|
||
|
a career academic biologist with decades of experience
|
||
|
|
||
|
01:07:17.000 --> 01:07:21.000
|
||
|
none of these people on the screen are claiming less than
|
||
|
|
||
|
01:07:21.000 --> 01:07:25.000
|
||
|
less experience than me and most of them I would assume
|
||
|
|
||
|
01:07:25.000 --> 01:07:28.000
|
||
|
are claiming more experience than me in virology
|
||
|
|
||
|
01:07:28.000 --> 01:07:31.000
|
||
|
and in biology in general
|
||
|
|
||
|
01:07:31.000 --> 01:07:34.000
|
||
|
so every one of these people should be my academic
|
||
|
|
||
|
01:07:34.000 --> 01:07:37.000
|
||
|
and intellectual elder
|
||
|
|
||
|
01:07:37.000 --> 01:07:40.000
|
||
|
and yet you're going to hear how
|
||
|
|
||
|
01:07:40.000 --> 01:07:43.000
|
||
|
absolutely elementary
|
||
|
|
||
|
01:07:43.000 --> 01:07:47.000
|
||
|
and naive they speak
|
||
|
|
||
|
01:07:47.000 --> 01:07:50.000
|
||
|
of these
|
||
|
|
||
|
01:07:50.000 --> 01:07:53.000
|
||
|
things that are portrayed as certainties by the CDC
|
||
|
|
||
|
01:07:53.000 --> 01:07:57.000
|
||
|
by the FDA, by the WHO, by everyone
|
||
|
|
||
|
01:07:57.000 --> 01:08:00.000
|
||
|
by the entire public health apparatus
|
||
|
|
||
|
01:08:00.000 --> 01:08:03.000
|
||
|
that is responsible for this illusion of consensus
|
||
|
|
||
|
01:08:03.000 --> 01:08:06.000
|
||
|
and they even actually get confused because they realize
|
||
|
|
||
|
01:08:06.000 --> 01:08:08.000
|
||
|
that wow there's a lot of
|
||
|
|
||
|
01:08:08.000 --> 01:08:10.000
|
||
|
there's a lot of hand waving here
|
||
|
|
||
|
01:08:10.000 --> 01:08:13.000
|
||
|
and Vincent tries to pull the
|
||
|
|
||
|
01:08:13.000 --> 01:08:16.000
|
||
|
shoot a little bit and keep them on topic
|
||
|
|
||
|
01:08:16.000 --> 01:08:19.000
|
||
|
but the guy in the upper right is sure not buying it
|
||
|
|
||
|
01:08:19.000 --> 01:08:23.000
|
||
|
and the guy in the lower right really tries to save the day too
|
||
|
|
||
|
01:08:23.000 --> 01:08:26.000
|
||
|
but I mean it's just an exposure like none other
|
||
|
|
||
|
01:08:26.000 --> 01:08:28.000
|
||
|
so let's check this out
|
||
|
|
||
|
01:08:28.000 --> 01:08:30.000
|
||
|
I don't know how long I'm taking here
|
||
|
|
||
|
01:08:30.000 --> 01:08:31.000
|
||
|
I'm probably really already
|
||
|
|
||
|
01:08:31.000 --> 01:08:33.000
|
||
|
hours and hours on
|
||
|
|
||
|
01:08:33.000 --> 01:08:35.000
|
||
|
here we go
|
||
|
|
||
|
01:08:35.000 --> 01:08:38.000
|
||
|
so I starting it at
|
||
|
|
||
|
01:08:38.000 --> 01:08:42.000
|
||
|
2358 because they read some other paper beforehand
|
||
|
|
||
|
01:08:42.000 --> 01:08:44.000
|
||
|
and it's only going to be about 15 minutes
|
||
|
|
||
|
01:08:44.000 --> 01:08:46.000
|
||
|
we're not going to listen to the whole thing
|
||
|
|
||
|
01:08:46.000 --> 01:08:48.000
|
||
|
I'm just going to listen to this paper
|
||
|
|
||
|
01:08:48.000 --> 01:08:51.000
|
||
|
and I'm going to listen at one and a half speed
|
||
|
|
||
|
01:08:51.000 --> 01:08:52.000
|
||
|
and then we'll close it out
|
||
|
|
||
|
01:08:52.000 --> 01:08:54.000
|
||
|
you know because that's how we're going to do it
|
||
|
|
||
|
01:08:54.000 --> 01:08:55.000
|
||
|
we're going to do dailies
|
||
|
|
||
|
01:08:55.000 --> 01:08:56.000
|
||
|
we're going to try and just keep
|
||
|
|
||
|
01:08:56.000 --> 01:08:57.000
|
||
|
singing the same song
|
||
|
|
||
|
01:08:57.000 --> 01:08:58.000
|
||
|
and if you don't like it
|
||
|
|
||
|
01:08:58.000 --> 01:08:59.000
|
||
|
well that's tough
|
||
|
|
||
|
01:08:59.000 --> 01:09:01.000
|
||
|
because the same song needs singing at this point
|
||
|
|
||
|
01:09:01.000 --> 01:09:03.000
|
||
|
we need to keep repeating stuff
|
||
|
|
||
|
01:09:03.000 --> 01:09:05.000
|
||
|
until people get it
|
||
|
|
||
|
01:09:05.000 --> 01:09:07.000
|
||
|
what is behind me?
|
||
|
|
||
|
01:09:07.000 --> 01:09:09.000
|
||
|
there's a wrinkle in my
|
||
|
|
||
|
01:09:09.000 --> 01:09:11.000
|
||
|
in my green screen
|
||
|
|
||
|
01:09:11.000 --> 01:09:13.000
|
||
|
it's making some annoying
|
||
|
|
||
|
01:09:13.000 --> 01:09:15.000
|
||
|
like there we go
|
||
|
|
||
|
01:09:15.000 --> 01:09:17.000
|
||
|
alright that's better
|
||
|
|
||
|
01:09:17.000 --> 01:09:19.000
|
||
|
oh good mistakes
|
||
|
|
||
|
01:09:19.000 --> 01:09:21.000
|
||
|
let's play
|
||
|
|
||
|
01:09:21.000 --> 01:09:24.000
|
||
|
yeah there was only two in the ellipsis
|
||
|
|
||
|
01:09:24.000 --> 01:09:26.000
|
||
|
it was three dots but only two names
|
||
|
|
||
|
01:09:26.000 --> 01:09:27.000
|
||
|
oh I read the main title
|
||
|
|
||
|
01:09:27.000 --> 01:09:28.000
|
||
|
with all the authors
|
||
|
|
||
|
01:09:28.000 --> 01:09:29.000
|
||
|
yeah okay
|
||
|
|
||
|
01:09:29.000 --> 01:09:30.000
|
||
|
one two three four five six seven eight
|
||
|
|
||
|
01:09:30.000 --> 01:09:31.000
|
||
|
yeah okay yeah the ellipsis
|
||
|
|
||
|
01:09:31.000 --> 01:09:32.000
|
||
|
I didn't read that right
|
||
|
|
||
|
01:09:32.000 --> 01:09:34.000
|
||
|
okay human papillomavirus
|
||
|
|
||
|
01:09:34.000 --> 01:09:35.000
|
||
|
now these are DNA viruses
|
||
|
|
||
|
01:09:35.000 --> 01:09:37.000
|
||
|
oh wait what did I say?
|
||
|
|
||
|
01:09:37.000 --> 01:09:39.000
|
||
|
human icosahedral capsid
|
||
|
|
||
|
01:09:39.000 --> 01:09:41.000
|
||
|
okay so here you go you can already see
|
||
|
|
||
|
01:09:41.000 --> 01:09:43.000
|
||
|
where I'm just not
|
||
|
|
||
|
01:09:43.000 --> 01:09:45.000
|
||
|
human papillomavirus is HPV vaccine
|
||
|
|
||
|
01:09:45.000 --> 01:09:47.000
|
||
|
I apologize what was I saying
|
||
|
|
||
|
01:09:47.000 --> 01:09:48.000
|
||
|
hepatitis like that's crazy
|
||
|
|
||
|
01:09:48.000 --> 01:09:50.000
|
||
|
that's the one they give at birth
|
||
|
|
||
|
01:09:50.000 --> 01:09:52.000
|
||
|
and they give it other types too
|
||
|
|
||
|
01:09:52.000 --> 01:09:54.000
|
||
|
so I apologize already for that ball drop
|
||
|
|
||
|
01:09:54.000 --> 01:09:56.000
|
||
|
HPV is human papillomavirus
|
||
|
|
||
|
01:09:56.000 --> 01:09:58.000
|
||
|
and those are the viruses
|
||
|
|
||
|
01:09:58.000 --> 01:10:00.000
|
||
|
that are blamed for cervical cancer
|
||
|
|
||
|
01:10:00.000 --> 01:10:01.000
|
||
|
and uterine cancer
|
||
|
|
||
|
01:10:01.000 --> 01:10:03.000
|
||
|
and all kinds of other genital cancers
|
||
|
|
||
|
01:10:03.000 --> 01:10:05.000
|
||
|
and so that's what we're talking about here
|
||
|
|
||
|
01:10:05.000 --> 01:10:07.000
|
||
|
and it's a niche
|
||
|
|
||
|
01:10:07.000 --> 01:10:08.000
|
||
|
for cervical cancer
|
||
|
|
||
|
01:10:08.000 --> 01:10:10.000
|
||
|
which is just ridiculous right
|
||
|
|
||
|
01:10:10.000 --> 01:10:12.000
|
||
|
for a number of biological reasons
|
||
|
|
||
|
01:10:12.000 --> 01:10:14.000
|
||
|
it's imprecise use of language
|
||
|
|
||
|
01:10:14.000 --> 01:10:16.000
|
||
|
that's really burning me up lately
|
||
|
|
||
|
01:10:16.000 --> 01:10:18.000
|
||
|
but it's it's burning me up
|
||
|
|
||
|
01:10:18.000 --> 01:10:19.000
|
||
|
because it's become obvious
|
||
|
|
||
|
01:10:19.000 --> 01:10:21.000
|
||
|
that that's not only what drove me nuts
|
||
|
|
||
|
01:10:21.000 --> 01:10:23.000
|
||
|
when I was in academic biology
|
||
|
|
||
|
01:10:23.000 --> 01:10:25.000
|
||
|
as a neurobiologist
|
||
|
|
||
|
01:10:25.000 --> 01:10:27.000
|
||
|
but it's what really drives me nuts
|
||
|
|
||
|
01:10:27.000 --> 01:10:29.000
|
||
|
about how we've moved through this pandemic
|
||
|
|
||
|
01:10:29.000 --> 01:10:31.000
|
||
|
it's with imprecise language
|
||
|
|
||
|
01:10:31.000 --> 01:10:34.000
|
||
|
it is making things stupid complicated
|
||
|
|
||
|
01:10:34.000 --> 01:10:36.000
|
||
|
or dumb simple when it's inappropriate
|
||
|
|
||
|
01:10:36.000 --> 01:10:38.000
|
||
|
to the point where people
|
||
|
|
||
|
01:10:38.000 --> 01:10:40.000
|
||
|
are completely bamboozled
|
||
|
|
||
|
01:10:40.000 --> 01:10:41.000
|
||
|
they're misled
|
||
|
|
||
|
01:10:41.000 --> 01:10:44.000
|
||
|
and they think they understand something
|
||
|
|
||
|
01:10:44.000 --> 01:10:46.000
|
||
|
that has been made dumb
|
||
|
|
||
|
01:10:46.000 --> 01:10:48.000
|
||
|
simple or stupid complicated
|
||
|
|
||
|
01:10:48.000 --> 01:10:50.000
|
||
|
and they don't
|
||
|
|
||
|
01:10:50.000 --> 01:10:53.000
|
||
|
and these people are going to
|
||
|
|
||
|
01:10:53.000 --> 01:10:56.000
|
||
|
inadvertently or unwittingly admit
|
||
|
|
||
|
01:10:56.000 --> 01:10:58.000
|
||
|
that they don't understand this either
|
||
|
|
||
|
01:10:58.000 --> 01:11:00.000
|
||
|
and it's sad
|
||
|
|
||
|
01:11:00.000 --> 01:11:02.000
|
||
|
because you can see them struggle
|
||
|
|
||
|
01:11:02.000 --> 01:11:03.000
|
||
|
through the mud
|
||
|
|
||
|
01:11:03.000 --> 01:11:05.000
|
||
|
like wow I really don't get it
|
||
|
|
||
|
01:11:05.000 --> 01:11:06.000
|
||
|
I mean it doesn't make sense
|
||
|
|
||
|
01:11:06.000 --> 01:11:07.000
|
||
|
but I guess we've got to accept it
|
||
|
|
||
|
01:11:07.000 --> 01:11:08.000
|
||
|
because we're a virologist
|
||
|
|
||
|
01:11:08.000 --> 01:11:10.000
|
||
|
and this is a virology paper
|
||
|
|
||
|
01:11:10.000 --> 01:11:12.000
|
||
|
brains and they are
|
||
|
|
||
|
01:11:12.000 --> 01:11:13.000
|
||
|
there are lots of them
|
||
|
|
||
|
01:11:13.000 --> 01:11:14.000
|
||
|
there are many different types
|
||
|
|
||
|
01:11:14.000 --> 01:11:17.000
|
||
|
and many of them are associated
|
||
|
|
||
|
01:11:17.000 --> 01:11:19.000
|
||
|
with producing warts
|
||
|
|
||
|
01:11:19.000 --> 01:11:20.000
|
||
|
and humans
|
||
|
|
||
|
01:11:20.000 --> 01:11:21.000
|
||
|
for human papilloma viruses
|
||
|
|
||
|
01:11:21.000 --> 01:11:23.000
|
||
|
of course are rabbit papilloma viruses as well
|
||
|
|
||
|
01:11:23.000 --> 01:11:25.000
|
||
|
but in humans some of the types
|
||
|
|
||
|
01:11:25.000 --> 01:11:26.000
|
||
|
are associated with cancers
|
||
|
|
||
|
01:11:26.000 --> 01:11:28.000
|
||
|
such as cervical cancer, anal cancer,
|
||
|
|
||
|
01:11:28.000 --> 01:11:29.000
|
||
|
vaginal cancer, vulvar cancer
|
||
|
|
||
|
01:11:29.000 --> 01:11:31.000
|
||
|
and also oral pharyngeal cancer
|
||
|
|
||
|
01:11:31.000 --> 01:11:32.000
|
||
|
and a number of years ago
|
||
|
|
||
|
01:11:32.000 --> 01:11:34.000
|
||
|
vaccines were developed
|
||
|
|
||
|
01:11:34.000 --> 01:11:36.000
|
||
|
to specifically prevent these cancers
|
||
|
|
||
|
01:11:36.000 --> 01:11:38.000
|
||
|
and they're very good at doing that
|
||
|
|
||
|
01:11:38.000 --> 01:11:40.000
|
||
|
they're interesting vaccines
|
||
|
|
||
|
01:11:40.000 --> 01:11:42.000
|
||
|
because they're virus-like particles
|
||
|
|
||
|
01:11:42.000 --> 01:11:44.000
|
||
|
there's a genome in them
|
||
|
|
||
|
01:11:44.000 --> 01:11:46.000
|
||
|
the main capsid protein is produced in
|
||
|
|
||
|
01:11:46.000 --> 01:11:48.000
|
||
|
like yeast or insect cells
|
||
|
|
||
|
01:11:48.000 --> 01:11:49.000
|
||
|
it assembles into a particle
|
||
|
|
||
|
01:11:49.000 --> 01:11:50.000
|
||
|
it's mixed with an adjuvant
|
||
|
|
||
|
01:11:50.000 --> 01:11:52.000
|
||
|
and they're very good at preventing cancers
|
||
|
|
||
|
01:11:52.000 --> 01:11:54.000
|
||
|
so they've been widely adopted
|
||
|
|
||
|
01:11:54.000 --> 01:11:56.000
|
||
|
and of course the best time to give them
|
||
|
|
||
|
01:11:56.000 --> 01:11:58.000
|
||
|
is before people become sexually active
|
||
|
|
||
|
01:11:58.000 --> 01:11:59.000
|
||
|
so you don't acquire these viruses naturally
|
||
|
|
||
|
01:11:59.000 --> 01:12:00.000
|
||
|
which is when they become a problem
|
||
|
|
||
|
01:12:00.000 --> 01:12:02.000
|
||
|
so you can prevent disease by vaccinating
|
||
|
|
||
|
01:12:02.000 --> 01:12:04.000
|
||
|
so it's weird because he says
|
||
|
|
||
|
01:12:04.000 --> 01:12:07.000
|
||
|
that you prevent disease by vaccinating
|
||
|
|
||
|
01:12:07.000 --> 01:12:09.000
|
||
|
and it's better to vaccinate people younger
|
||
|
|
||
|
01:12:09.000 --> 01:12:11.000
|
||
|
because you acquire these viruses
|
||
|
|
||
|
01:12:11.000 --> 01:12:13.000
|
||
|
through sexual activity
|
||
|
|
||
|
01:12:13.000 --> 01:12:19.000
|
||
|
so the idea is apparently
|
||
|
|
||
|
01:12:19.000 --> 01:12:21.000
|
||
|
that you don't have any of these viruses
|
||
|
|
||
|
01:12:21.000 --> 01:12:23.000
|
||
|
until you start sleeping with people
|
||
|
|
||
|
01:12:23.000 --> 01:12:25.000
|
||
|
but where do those people get them?
|
||
|
|
||
|
01:12:25.000 --> 01:12:29.000
|
||
|
basically already the biology is off the rails
|
||
|
|
||
|
01:12:29.000 --> 01:12:31.000
|
||
|
basically he's already telling you
|
||
|
|
||
|
01:12:31.000 --> 01:12:32.000
|
||
|
in a minimal mythology story
|
||
|
|
||
|
01:12:32.000 --> 01:12:34.000
|
||
|
that has no basis in reality
|
||
|
|
||
|
01:12:34.000 --> 01:12:36.000
|
||
|
and you can just dissect it
|
||
|
|
||
|
01:12:36.000 --> 01:12:39.000
|
||
|
with common sense
|
||
|
|
||
|
01:12:44.000 --> 01:12:46.000
|
||
|
and it's extraordinary really
|
||
|
|
||
|
01:12:46.000 --> 01:12:48.000
|
||
|
how accepted
|
||
|
|
||
|
01:12:48.000 --> 01:12:50.000
|
||
|
and accepting
|
||
|
|
||
|
01:12:50.000 --> 01:12:52.000
|
||
|
the three of these people are
|
||
|
|
||
|
01:12:52.000 --> 01:12:54.000
|
||
|
as he says these ridiculous things
|
||
|
|
||
|
01:12:54.000 --> 01:12:57.000
|
||
|
that they're really good at preventing cancer
|
||
|
|
||
|
01:12:57.000 --> 01:12:59.000
|
||
|
and that giving them early
|
||
|
|
||
|
01:12:59.000 --> 01:13:01.000
|
||
|
is the way they work the best
|
||
|
|
||
|
01:13:01.000 --> 01:13:03.000
|
||
|
because you get these viruses
|
||
|
|
||
|
01:13:03.000 --> 01:13:04.000
|
||
|
through sexual activity
|
||
|
|
||
|
01:13:04.000 --> 01:13:07.000
|
||
|
so we have to give the vaccine
|
||
|
|
||
|
01:13:07.000 --> 01:13:09.000
|
||
|
before the sexual activity starts
|
||
|
|
||
|
01:13:09.000 --> 01:13:13.000
|
||
|
I mean how these things are connected
|
||
|
|
||
|
01:13:13.000 --> 01:13:15.000
|
||
|
in his mind is just
|
||
|
|
||
|
01:13:15.000 --> 01:13:18.000
|
||
|
it's bewildering to me
|
||
|
|
||
|
01:13:18.000 --> 01:13:21.000
|
||
|
that they can even speak these words out loud
|
||
|
|
||
|
01:13:21.000 --> 01:13:24.000
|
||
|
and not be disgusted with themselves
|
||
|
|
||
|
01:13:24.000 --> 01:13:27.000
|
||
|
because you have to know that these are lies
|
||
|
|
||
|
01:13:27.000 --> 01:13:29.000
|
||
|
you have to know that these are gross
|
||
|
|
||
|
01:13:29.000 --> 01:13:33.000
|
||
|
oversimplifications of something that we obviously know
|
||
|
|
||
|
01:13:33.000 --> 01:13:36.000
|
||
|
is a lot more complicated than this
|
||
|
|
||
|
01:13:36.000 --> 01:13:39.000
|
||
|
so there are lots and lots of stereotypes of these
|
||
|
|
||
|
01:13:39.000 --> 01:13:41.000
|
||
|
but it's only a few of them
|
||
|
|
||
|
01:13:41.000 --> 01:13:43.000
|
||
|
that account for the overwhelming majority
|
||
|
|
||
|
01:13:43.000 --> 01:13:45.000
|
||
|
essentially all of the cancers
|
||
|
|
||
|
01:13:45.000 --> 01:13:47.000
|
||
|
and that's 16 and 18
|
||
|
|
||
|
01:13:47.000 --> 01:13:49.000
|
||
|
HPV 16 and HPV 18
|
||
|
|
||
|
01:13:49.000 --> 01:13:51.000
|
||
|
are the targets of the vaccine that they're looking at here
|
||
|
|
||
|
01:13:51.000 --> 01:13:53.000
|
||
|
31 and 45, too
|
||
|
|
||
|
01:13:53.000 --> 01:13:54.000
|
||
|
31 and 40
|
||
|
|
||
|
01:13:54.000 --> 01:13:55.000
|
||
|
oops 31 and 45, too
|
||
|
|
||
|
01:13:55.000 --> 01:13:57.000
|
||
|
so I guess I don't know what I'm talking about at all
|
||
|
|
||
|
01:13:57.000 --> 01:13:59.000
|
||
|
but I read the paper and I'm really smart
|
||
|
|
||
|
01:13:59.000 --> 01:14:01.000
|
||
|
5, too, that's right
|
||
|
|
||
|
01:14:01.000 --> 01:14:03.000
|
||
|
and the question I have is with all those types
|
||
|
|
||
|
01:14:03.000 --> 01:14:05.000
|
||
|
does this vaccine come?
|
||
|
|
||
|
01:14:05.000 --> 01:14:07.000
|
||
|
There's also a
|
||
|
|
||
|
01:14:07.000 --> 01:14:09.000
|
||
|
9-valent
|
||
|
|
||
|
01:14:09.000 --> 01:14:11.000
|
||
|
vaccine, Gardasil 9
|
||
|
|
||
|
01:14:11.000 --> 01:14:13.000
|
||
|
in the paper
|
||
|
|
||
|
01:14:13.000 --> 01:14:15.000
|
||
|
so really we're looking at
|
||
|
|
||
|
01:14:15.000 --> 01:14:17.000
|
||
|
4 academic scientists
|
||
|
|
||
|
01:14:17.000 --> 01:14:19.000
|
||
|
with their own podcast that's already funded
|
||
|
|
||
|
01:14:19.000 --> 01:14:21.000
|
||
|
that has a studio
|
||
|
|
||
|
01:14:21.000 --> 01:14:23.000
|
||
|
and staff in Manhattan
|
||
|
|
||
|
01:14:23.000 --> 01:14:25.000
|
||
|
that's on their thousandth episode
|
||
|
|
||
|
01:14:25.000 --> 01:14:28.000
|
||
|
and they still don't have the basic biology
|
||
|
|
||
|
01:14:28.000 --> 01:14:30.000
|
||
|
of human papilloma virus
|
||
|
|
||
|
01:14:30.000 --> 01:14:32.000
|
||
|
one of the most successful
|
||
|
|
||
|
01:14:32.000 --> 01:14:34.000
|
||
|
and successful products
|
||
|
|
||
|
01:14:34.000 --> 01:14:36.000
|
||
|
of the Merck company
|
||
|
|
||
|
01:14:36.000 --> 01:14:38.000
|
||
|
they have no idea
|
||
|
|
||
|
01:14:38.000 --> 01:14:40.000
|
||
|
they have no concept
|
||
|
|
||
|
01:14:40.000 --> 01:14:42.000
|
||
|
they don't feel any obligation
|
||
|
|
||
|
01:14:42.000 --> 01:14:44.000
|
||
|
and any responsibility to be
|
||
|
|
||
|
01:14:44.000 --> 01:14:46.000
|
||
|
informed about it
|
||
|
|
||
|
01:14:46.000 --> 01:14:48.000
|
||
|
even as they hope that they get a million views
|
||
|
|
||
|
01:14:48.000 --> 01:14:50.000
|
||
|
even as they think
|
||
|
|
||
|
01:14:50.000 --> 01:14:52.000
|
||
|
that they are working with Earth's
|
||
|
|
||
|
01:14:52.000 --> 01:14:54.000
|
||
|
virology teacher
|
||
|
|
||
|
01:14:54.000 --> 01:14:56.000
|
||
|
understand how
|
||
|
|
||
|
01:14:56.000 --> 01:14:58.000
|
||
|
despicable this is
|
||
|
|
||
|
01:14:58.000 --> 01:15:00.000
|
||
|
no
|
||
|
|
||
|
01:15:00.000 --> 01:15:02.000
|
||
|
31 and 45, too
|
||
|
|
||
|
01:15:02.000 --> 01:15:04.000
|
||
|
31 and 45, too
|
||
|
|
||
|
01:15:04.000 --> 01:15:06.000
|
||
|
that's right
|
||
|
|
||
|
01:15:06.000 --> 01:15:08.000
|
||
|
the question I have is with all those types
|
||
|
|
||
|
01:15:08.000 --> 01:15:10.000
|
||
|
does this vaccine cover all them as well?
|
||
|
|
||
|
01:15:10.000 --> 01:15:12.000
|
||
|
no
|
||
|
|
||
|
01:15:12.000 --> 01:15:14.000
|
||
|
if you get the vaccine
|
||
|
|
||
|
01:15:14.000 --> 01:15:16.000
|
||
|
are you susceptible still to the ones
|
||
|
|
||
|
01:15:16.000 --> 01:15:18.000
|
||
|
that they didn't include into the vaccine?
|
||
|
|
||
|
01:15:18.000 --> 01:15:20.000
|
||
|
yes
|
||
|
|
||
|
01:15:20.000 --> 01:15:22.000
|
||
|
and there's not 100 serotypes
|
||
|
|
||
|
01:15:22.000 --> 01:15:24.000
|
||
|
there are more than 200 serotypes
|
||
|
|
||
|
01:15:24.000 --> 01:15:26.000
|
||
|
of the human papilloma virus
|
||
|
|
||
|
01:15:28.000 --> 01:15:30.000
|
||
|
and the best vaccine
|
||
|
|
||
|
01:15:30.000 --> 01:15:32.000
|
||
|
Gardasil 9
|
||
|
|
||
|
01:15:32.000 --> 01:15:34.000
|
||
|
purports to target
|
||
|
|
||
|
01:15:34.000 --> 01:15:36.000
|
||
|
9 of those serotypes
|
||
|
|
||
|
01:15:38.000 --> 01:15:40.000
|
||
|
now if you're not aware
|
||
|
|
||
|
01:15:40.000 --> 01:15:42.000
|
||
|
about how a niche works
|
||
|
|
||
|
01:15:42.000 --> 01:15:44.000
|
||
|
a niche is for a single species
|
||
|
|
||
|
01:15:44.000 --> 01:15:48.000
|
||
|
and species compete to occupy a niche
|
||
|
|
||
|
01:15:48.000 --> 01:15:50.000
|
||
|
if two species
|
||
|
|
||
|
01:15:50.000 --> 01:15:52.000
|
||
|
can occupy the same niche
|
||
|
|
||
|
01:15:52.000 --> 01:15:56.000
|
||
|
it's not really a niche anymore
|
||
|
|
||
|
01:15:56.000 --> 01:15:58.000
|
||
|
and yet we're going to
|
||
|
|
||
|
01:15:58.000 --> 01:16:00.000
|
||
|
argue and discuss
|
||
|
|
||
|
01:16:00.000 --> 01:16:02.000
|
||
|
the use of these terms
|
||
|
|
||
|
01:16:02.000 --> 01:16:04.000
|
||
|
and whether or not it's appropriate for
|
||
|
|
||
|
01:16:04.000 --> 01:16:06.000
|
||
|
something that's actually not even alive
|
||
|
|
||
|
01:16:06.000 --> 01:16:08.000
|
||
|
that's actually doesn't have
|
||
|
|
||
|
01:16:08.000 --> 01:16:10.000
|
||
|
species but has a quasi-species
|
||
|
|
||
|
01:16:10.000 --> 01:16:12.000
|
||
|
swarm
|
||
|
|
||
|
01:16:12.000 --> 01:16:14.000
|
||
|
and that can generate new variants
|
||
|
|
||
|
01:16:14.000 --> 01:16:16.000
|
||
|
through recombination
|
||
|
|
||
|
01:16:16.000 --> 01:16:18.000
|
||
|
and generates new variants
|
||
|
|
||
|
01:16:18.000 --> 01:16:22.000
|
||
|
through consistent replication errors
|
||
|
|
||
|
01:16:22.000 --> 01:16:24.000
|
||
|
they are
|
||
|
|
||
|
01:16:24.000 --> 01:16:28.000
|
||
|
completely off their skis here
|
||
|
|
||
|
01:16:28.000 --> 01:16:30.000
|
||
|
and careening
|
||
|
|
||
|
01:16:30.000 --> 01:16:32.000
|
||
|
into a ditch
|
||
|
|
||
|
01:16:32.000 --> 01:16:34.000
|
||
|
and the only thing that they can do
|
||
|
|
||
|
01:16:34.000 --> 01:16:36.000
|
||
|
is do it as gracefully as possible
|
||
|
|
||
|
01:16:36.000 --> 01:16:38.000
|
||
|
in hopes that the vast majority
|
||
|
|
||
|
01:16:38.000 --> 01:16:40.000
|
||
|
of their viewers
|
||
|
|
||
|
01:16:40.000 --> 01:16:42.000
|
||
|
are unsophisticated enough
|
||
|
|
||
|
01:16:42.000 --> 01:16:44.000
|
||
|
to see the train wreck
|
||
|
|
||
|
01:16:44.000 --> 01:16:46.000
|
||
|
for what it is
|
||
|
|
||
|
01:16:46.000 --> 01:16:48.000
|
||
|
the one that really has trouble
|
||
|
|
||
|
01:16:48.000 --> 01:16:50.000
|
||
|
with it is Alan Dove
|
||
|
|
||
|
01:16:50.000 --> 01:16:52.000
|
||
|
down here in the bottom
|
||
|
|
||
|
01:16:52.000 --> 01:16:54.000
|
||
|
he's really having glitch outs
|
||
|
|
||
|
01:16:54.000 --> 01:16:56.000
|
||
|
you know like I've got to argue
|
||
|
|
||
|
01:16:56.000 --> 01:16:58.000
|
||
|
for the mythology
|
||
|
|
||
|
01:16:58.000 --> 01:17:00.000
|
||
|
that I believe in
|
||
|
|
||
|
01:17:00.000 --> 01:17:02.000
|
||
|
even though the guy above me here
|
||
|
|
||
|
01:17:02.000 --> 01:17:04.000
|
||
|
is really really
|
||
|
|
||
|
01:17:04.000 --> 01:17:06.000
|
||
|
hitting home runs
|
||
|
|
||
|
01:17:06.000 --> 01:17:08.000
|
||
|
I've got to make fun of this old man
|
||
|
|
||
|
01:17:08.000 --> 01:17:10.000
|
||
|
we're going to all collectively make fun of this old man
|
||
|
|
||
|
01:17:10.000 --> 01:17:12.000
|
||
|
so that in the end
|
||
|
|
||
|
01:17:12.000 --> 01:17:14.000
|
||
|
the illusion of consensus
|
||
|
|
||
|
01:17:14.000 --> 01:17:16.000
|
||
|
will be sustained
|
||
|
|
||
|
01:17:16.000 --> 01:17:18.000
|
||
|
watch this train wreck
|
||
|
|
||
|
01:17:18.000 --> 01:17:20.000
|
||
|
but they've included in the vaccines
|
||
|
|
||
|
01:17:20.000 --> 01:17:22.000
|
||
|
the highest risk types right
|
||
|
|
||
|
01:17:22.000 --> 01:17:24.000
|
||
|
so you know
|
||
|
|
||
|
01:17:24.000 --> 01:17:26.000
|
||
|
as was mentioned actually
|
||
|
|
||
|
01:17:26.000 --> 01:17:28.000
|
||
|
included into the vaccine
|
||
|
|
||
|
01:17:28.000 --> 01:17:30.000
|
||
|
if you get the vaccine are you susceptible
|
||
|
|
||
|
01:17:30.000 --> 01:17:32.000
|
||
|
still to the ones that they didn't include
|
||
|
|
||
|
01:17:32.000 --> 01:17:34.000
|
||
|
into the vaccine? Yes
|
||
|
|
||
|
01:17:34.000 --> 01:17:36.000
|
||
|
but they've included in the vaccines
|
||
|
|
||
|
01:17:36.000 --> 01:17:38.000
|
||
|
the highest risk types right
|
||
|
|
||
|
01:17:38.000 --> 01:17:40.000
|
||
|
so you know as was mentioned
|
||
|
|
||
|
01:17:40.000 --> 01:17:42.000
|
||
|
actually so there's a nine-valent
|
||
|
|
||
|
01:17:42.000 --> 01:17:44.000
|
||
|
HPV vaccine which has the most different types
|
||
|
|
||
|
01:17:44.000 --> 01:17:46.000
|
||
|
it covers 611, 16, 18, 33,
|
||
|
|
||
|
01:17:46.000 --> 01:17:48.000
|
||
|
45, 52 and 58
|
||
|
|
||
|
01:17:48.000 --> 01:17:50.000
|
||
|
right so it's been updated over the years the original was 16 and 18
|
||
|
|
||
|
01:17:50.000 --> 01:17:52.000
|
||
|
which are the big really bad ones and then they've
|
||
|
|
||
|
01:17:52.000 --> 01:17:54.000
|
||
|
kind of punched down the list
|
||
|
|
||
|
01:17:54.000 --> 01:17:56.000
|
||
|
getting more and more and this nine-valent
|
||
|
|
||
|
01:17:56.000 --> 01:17:58.000
|
||
|
I guess is the latest iteration that
|
||
|
|
||
|
01:17:58.000 --> 01:18:00.000
|
||
|
why is he even talking
|
||
|
|
||
|
01:18:00.000 --> 01:18:02.000
|
||
|
five minutes ago he said that this
|
||
|
|
||
|
01:18:02.000 --> 01:18:04.000
|
||
|
this vaccine that they're talking about
|
||
|
|
||
|
01:18:04.000 --> 01:18:06.000
|
||
|
in this paper targeted two
|
||
|
|
||
|
01:18:06.000 --> 01:18:08.000
|
||
|
of the 200 plus
|
||
|
|
||
|
01:18:08.000 --> 01:18:10.000
|
||
|
zero-zero types
|
||
|
|
||
|
01:18:10.000 --> 01:18:12.000
|
||
|
then
|
||
|
|
||
|
01:18:12.000 --> 01:18:14.000
|
||
|
the lady over here corrects him and says
|
||
|
|
||
|
01:18:14.000 --> 01:18:16.000
|
||
|
no there's two more
|
||
|
|
||
|
01:18:16.000 --> 01:18:18.000
|
||
|
and finally we say well yeah there's also
|
||
|
|
||
|
01:18:18.000 --> 01:18:20.000
|
||
|
a nine-valent one
|
||
|
|
||
|
01:18:20.000 --> 01:18:22.000
|
||
|
and then he pipes in and says
|
||
|
|
||
|
01:18:22.000 --> 01:18:24.000
|
||
|
oh yeah well yeah this is the way it is
|
||
|
|
||
|
01:18:24.000 --> 01:18:28.000
|
||
|
because that's how these people have a discussion
|
||
|
|
||
|
01:18:28.000 --> 01:18:32.000
|
||
|
that's how they think discussion
|
||
|
|
||
|
01:18:32.000 --> 01:18:34.000
|
||
|
goes
|
||
|
|
||
|
01:18:34.000 --> 01:18:36.000
|
||
|
is some kind of
|
||
|
|
||
|
01:18:36.000 --> 01:18:40.000
|
||
|
agreement festival
|
||
|
|
||
|
01:18:40.000 --> 01:18:42.000
|
||
|
oh yes you're right I agree with you and repeat
|
||
|
|
||
|
01:18:42.000 --> 01:18:44.000
|
||
|
what they said
|
||
|
|
||
|
01:18:44.000 --> 01:18:46.000
|
||
|
that's not discussion
|
||
|
|
||
|
01:18:46.000 --> 01:18:48.000
|
||
|
that's not science happening
|
||
|
|
||
|
01:18:48.000 --> 01:18:50.000
|
||
|
this isn't a guy who's on his game
|
||
|
|
||
|
01:18:50.000 --> 01:18:54.000
|
||
|
this is a guy who's posing
|
||
|
|
||
|
01:18:54.000 --> 01:18:56.000
|
||
|
there's no other way to see it
|
||
|
|
||
|
01:18:56.000 --> 01:18:58.000
|
||
|
he should be ashamed of himself
|
||
|
|
||
|
01:18:58.000 --> 01:19:00.000
|
||
|
that he should have said wow I
|
||
|
|
||
|
01:19:00.000 --> 01:19:04.000
|
||
|
didn't realize this because I just started by saying there's only two
|
||
|
|
||
|
01:19:04.000 --> 01:19:06.000
|
||
|
targeted
|
||
|
|
||
|
01:19:06.000 --> 01:19:08.000
|
||
|
I mean
|
||
|
|
||
|
01:19:08.000 --> 01:19:10.000
|
||
|
how is it even possible
|
||
|
|
||
|
01:19:10.000 --> 01:19:12.000
|
||
|
that people take this seriously
|
||
|
|
||
|
01:19:12.000 --> 01:19:14.000
|
||
|
other than the fact that we have been
|
||
|
|
||
|
01:19:14.000 --> 01:19:16.000
|
||
|
misled for decades
|
||
|
|
||
|
01:19:16.000 --> 01:19:20.000
|
||
|
it's the only way to explain it
|
||
|
|
||
|
01:19:20.000 --> 01:19:22.000
|
||
|
um that takes out
|
||
|
|
||
|
01:19:22.000 --> 01:19:24.000
|
||
|
or generates antibodies against a larger panel
|
||
|
|
||
|
01:19:24.000 --> 01:19:26.000
|
||
|
so Vincent would you
|
||
|
|
||
|
01:19:26.000 --> 01:19:28.000
|
||
|
summarize that what is the goal of this research
|
||
|
|
||
|
01:19:28.000 --> 01:19:30.000
|
||
|
so he made another assumption there
|
||
|
|
||
|
01:19:30.000 --> 01:19:32.000
|
||
|
he said that this
|
||
|
|
||
|
01:19:32.000 --> 01:19:34.000
|
||
|
listen he says that this
|
||
|
|
||
|
01:19:34.000 --> 01:19:36.000
|
||
|
and this nine-valent I guess is the latest iteration
|
||
|
|
||
|
01:19:36.000 --> 01:19:38.000
|
||
|
that takes out or generates
|
||
|
|
||
|
01:19:38.000 --> 01:19:40.000
|
||
|
antibodies against a larger panel
|
||
|
|
||
|
01:19:40.000 --> 01:19:42.000
|
||
|
so he's just thinking out loud
|
||
|
|
||
|
01:19:42.000 --> 01:19:44.000
|
||
|
that I guess they have this nine-valent
|
||
|
|
||
|
01:19:44.000 --> 01:19:46.000
|
||
|
one that makes up
|
||
|
|
||
|
01:19:46.000 --> 01:19:48.000
|
||
|
antibodies against a larger panel
|
||
|
|
||
|
01:19:48.000 --> 01:19:52.000
|
||
|
now that I just heard
|
||
|
|
||
|
01:19:52.000 --> 01:19:54.000
|
||
|
that there is a Gardasil-9
|
||
|
|
||
|
01:19:54.000 --> 01:19:56.000
|
||
|
I guess the way that it must work
|
||
|
|
||
|
01:19:56.000 --> 01:19:58.000
|
||
|
is that it targets a whole panel of viruses
|
||
|
|
||
|
01:19:58.000 --> 01:20:00.000
|
||
|
you know
|
||
|
|
||
|
01:20:00.000 --> 01:20:02.000
|
||
|
five minutes ago I thought that there was just
|
||
|
|
||
|
01:20:02.000 --> 01:20:04.000
|
||
|
Gardasil-2 but I guess there's
|
||
|
|
||
|
01:20:04.000 --> 01:20:06.000
|
||
|
Gardasil-9 so cool wow
|
||
|
|
||
|
01:20:06.000 --> 01:20:08.000
|
||
|
it's like learning in real time
|
||
|
|
||
|
01:20:08.000 --> 01:20:10.000
|
||
|
I feel really smart now
|
||
|
|
||
|
01:20:14.000 --> 01:20:16.000
|
||
|
we're talking about
|
||
|
|
||
|
01:20:16.000 --> 01:20:18.000
|
||
|
vaccinating teenage girls
|
||
|
|
||
|
01:20:18.000 --> 01:20:20.000
|
||
|
that don't need to be vaccinated
|
||
|
|
||
|
01:20:20.000 --> 01:20:22.000
|
||
|
that are
|
||
|
|
||
|
01:20:22.000 --> 01:20:24.000
|
||
|
we're talking about injecting
|
||
|
|
||
|
01:20:24.000 --> 01:20:26.000
|
||
|
a combination of substances
|
||
|
|
||
|
01:20:26.000 --> 01:20:28.000
|
||
|
intramuscularly
|
||
|
|
||
|
01:20:28.000 --> 01:20:30.000
|
||
|
to augment the immune system
|
||
|
|
||
|
01:20:30.000 --> 01:20:32.000
|
||
|
of healthy young teenage girls
|
||
|
|
||
|
01:20:32.000 --> 01:20:36.000
|
||
|
and boys
|
||
|
|
||
|
01:20:36.000 --> 01:20:38.000
|
||
|
to protect them from viruses
|
||
|
|
||
|
01:20:38.000 --> 01:20:40.000
|
||
|
that have more than
|
||
|
|
||
|
01:20:40.000 --> 01:20:42.000
|
||
|
200 seroprevalent type
|
||
|
|
||
|
01:20:42.000 --> 01:20:44.000
|
||
|
serotypes
|
||
|
|
||
|
01:20:44.000 --> 01:20:46.000
|
||
|
more than 200
|
||
|
|
||
|
01:20:46.000 --> 01:20:48.000
|
||
|
serotypes we are attempting
|
||
|
|
||
|
01:20:48.000 --> 01:20:50.000
|
||
|
to
|
||
|
|
||
|
01:20:50.000 --> 01:20:52.000
|
||
|
augment the immune system
|
||
|
|
||
|
01:20:52.000 --> 01:20:54.000
|
||
|
of healthy teenagers
|
||
|
|
||
|
01:20:54.000 --> 01:20:56.000
|
||
|
and
|
||
|
|
||
|
01:20:56.000 --> 01:20:58.000
|
||
|
the amount of responsibility
|
||
|
|
||
|
01:20:58.000 --> 01:21:00.000
|
||
|
that
|
||
|
|
||
|
01:21:00.000 --> 01:21:02.000
|
||
|
professor Dove feels
|
||
|
|
||
|
01:21:02.000 --> 01:21:04.000
|
||
|
to all those teenagers
|
||
|
|
||
|
01:21:04.000 --> 01:21:06.000
|
||
|
is that he was
|
||
|
|
||
|
01:21:06.000 --> 01:21:08.000
|
||
|
vaguely aware that there was
|
||
|
|
||
|
01:21:08.000 --> 01:21:10.000
|
||
|
a human papillomavirus vaccine
|
||
|
|
||
|
01:21:10.000 --> 01:21:12.000
|
||
|
that was dual valent
|
||
|
|
||
|
01:21:12.000 --> 01:21:14.000
|
||
|
trivalent is there a quadrivalent
|
||
|
|
||
|
01:21:14.000 --> 01:21:16.000
|
||
|
one oh there's a nine valent
|
||
|
|
||
|
01:21:16.000 --> 01:21:18.000
|
||
|
one wow that's
|
||
|
|
||
|
01:21:18.000 --> 01:21:20.000
|
||
|
that's impressive I guess that one develops immunity
|
||
|
|
||
|
01:21:20.000 --> 01:21:22.000
|
||
|
against a whole panel
|
||
|
|
||
|
01:21:22.000 --> 01:21:24.000
|
||
|
of human papillomaviruses
|
||
|
|
||
|
01:21:24.000 --> 01:21:26.000
|
||
|
boy technology's
|
||
|
|
||
|
01:21:26.000 --> 01:21:28.000
|
||
|
amazing isn't it Dr. Dove
|
||
|
|
||
|
01:21:30.000 --> 01:21:32.000
|
||
|
Alan Dove
|
||
|
|
||
|
01:21:33.000 --> 01:21:35.000
|
||
|
wow I mean I'm just shocked
|
||
|
|
||
|
01:21:36.000 --> 01:21:38.000
|
||
|
Vincent would you summarize then
|
||
|
|
||
|
01:21:38.000 --> 01:21:40.000
|
||
|
what is the goal of this research?
|
||
|
|
||
|
01:21:40.000 --> 01:21:42.000
|
||
|
Oh the goal is a viral ecology
|
||
|
|
||
|
01:21:42.000 --> 01:21:44.000
|
||
|
yeah I'm a little confused about
|
||
|
|
||
|
01:21:44.000 --> 01:21:46.000
|
||
|
well right so if you vaccinate against
|
||
|
|
||
|
01:21:46.000 --> 01:21:48.000
|
||
|
a few serotypes
|
||
|
|
||
|
01:21:48.000 --> 01:21:50.000
|
||
|
there are all these other serotypes circulating around
|
||
|
|
||
|
01:21:50.000 --> 01:21:52.000
|
||
|
and that happens to the ecology of this virus
|
||
|
|
||
|
01:21:52.000 --> 01:21:54.000
|
||
|
now that you've
|
||
|
|
||
|
01:21:54.000 --> 01:21:56.000
|
||
|
well if your vaccination is successful
|
||
|
|
||
|
01:21:56.000 --> 01:21:58.000
|
||
|
you hope to take those serotypes out of the equation
|
||
|
|
||
|
01:21:58.000 --> 01:22:00.000
|
||
|
maybe eradicate them in quotes
|
||
|
|
||
|
01:22:00.000 --> 01:22:02.000
|
||
|
at least from local population
|
||
|
|
||
|
01:22:02.000 --> 01:22:04.000
|
||
|
and then do the other viruses
|
||
|
|
||
|
01:22:04.000 --> 01:22:06.000
|
||
|
change their proportions in the population
|
||
|
|
||
|
01:22:06.000 --> 01:22:08.000
|
||
|
but remember what
|
||
|
|
||
|
01:22:08.000 --> 01:22:10.000
|
||
|
what we started with right
|
||
|
|
||
|
01:22:10.000 --> 01:22:12.000
|
||
|
Vincent said that you give this
|
||
|
|
||
|
01:22:12.000 --> 01:22:14.000
|
||
|
this vaccine to kids before
|
||
|
|
||
|
01:22:14.000 --> 01:22:16.000
|
||
|
they get the virus
|
||
|
|
||
|
01:22:16.000 --> 01:22:18.000
|
||
|
one representation of HPV vaccine
|
||
|
|
||
|
01:22:18.000 --> 01:22:20.000
|
||
|
is that you give it to them
|
||
|
|
||
|
01:22:20.000 --> 01:22:22.000
|
||
|
so that they don't get these
|
||
|
|
||
|
01:22:22.000 --> 01:22:24.000
|
||
|
these dangerous
|
||
|
|
||
|
01:22:24.000 --> 01:22:26.000
|
||
|
human papillomaviruses
|
||
|
|
||
|
01:22:26.000 --> 01:22:28.000
|
||
|
from their sexual activities
|
||
|
|
||
|
01:22:28.000 --> 01:22:30.000
|
||
|
and they don't spread them
|
||
|
|
||
|
01:22:30.000 --> 01:22:32.000
|
||
|
so the argument is going to be
|
||
|
|
||
|
01:22:32.000 --> 01:22:34.000
|
||
|
that the ones that they do have
|
||
|
|
||
|
01:22:34.000 --> 01:22:36.000
|
||
|
after vaccination
|
||
|
|
||
|
01:22:36.000 --> 01:22:38.000
|
||
|
obviously are safer
|
||
|
|
||
|
01:22:40.000 --> 01:22:42.000
|
||
|
but in this paper they don't look at
|
||
|
|
||
|
01:22:42.000 --> 01:22:44.000
|
||
|
cancer
|
||
|
|
||
|
01:22:44.000 --> 01:22:46.000
|
||
|
they don't even look at
|
||
|
|
||
|
01:22:46.000 --> 01:22:48.000
|
||
|
like warts
|
||
|
|
||
|
01:22:48.000 --> 01:22:50.000
|
||
|
or anything
|
||
|
|
||
|
01:22:50.000 --> 01:22:52.000
|
||
|
they look for PCR evidence
|
||
|
|
||
|
01:22:52.000 --> 01:22:54.000
|
||
|
of different
|
||
|
|
||
|
01:22:54.000 --> 01:22:56.000
|
||
|
serotypes
|
||
|
|
||
|
01:22:56.000 --> 01:22:58.000
|
||
|
of human papillomavirus
|
||
|
|
||
|
01:22:58.000 --> 01:23:00.000
|
||
|
and do they look for all of them
|
||
|
|
||
|
01:23:00.000 --> 01:23:02.000
|
||
|
they can't
|
||
|
|
||
|
01:23:02.000 --> 01:23:04.000
|
||
|
they can't
|
||
|
|
||
|
01:23:04.000 --> 01:23:08.000
|
||
|
they don't have that level of fidelity
|
||
|
|
||
|
01:23:10.000 --> 01:23:12.000
|
||
|
and they don't have that level of
|
||
|
|
||
|
01:23:12.000 --> 01:23:14.000
|
||
|
of data
|
||
|
|
||
|
01:23:14.000 --> 01:23:16.000
|
||
|
they don't have that level of vaccination
|
||
|
|
||
|
01:23:16.000 --> 01:23:18.000
|
||
|
that coverage of vaccination
|
||
|
|
||
|
01:23:18.000 --> 01:23:20.000
|
||
|
and so they need to use
|
||
|
|
||
|
01:23:20.000 --> 01:23:22.000
|
||
|
very special
|
||
|
|
||
|
01:23:22.000 --> 01:23:24.000
|
||
|
general linear models
|
||
|
|
||
|
01:23:24.000 --> 01:23:26.000
|
||
|
and
|
||
|
|
||
|
01:23:26.000 --> 01:23:29.000
|
||
|
apply mathematical simulations
|
||
|
|
||
|
01:23:29.000 --> 01:23:31.000
|
||
|
in order to create synthetic data
|
||
|
|
||
|
01:23:33.000 --> 01:23:35.000
|
||
|
and in that synthetic data
|
||
|
|
||
|
01:23:35.000 --> 01:23:37.000
|
||
|
they say that they can find a difference
|
||
|
|
||
|
01:23:37.000 --> 01:23:39.000
|
||
|
between populations that have been
|
||
|
|
||
|
01:23:39.000 --> 01:23:41.000
|
||
|
unvaccinated versus vaccinated
|
||
|
|
||
|
01:23:41.000 --> 01:23:43.000
|
||
|
and girls only versus vaccinated
|
||
|
|
||
|
01:23:43.000 --> 01:23:45.000
|
||
|
and boys and girls
|
||
|
|
||
|
01:23:50.000 --> 01:23:52.000
|
||
|
do you get more of those other
|
||
|
|
||
|
01:23:52.000 --> 01:23:54.000
|
||
|
relatively benign serotypes showing up
|
||
|
|
||
|
01:23:54.000 --> 01:23:55.000
|
||
|
or does everybody stay the same?
|
||
|
|
||
|
01:23:55.000 --> 01:23:57.000
|
||
|
you just get a total reduction in the amount of HPV
|
||
|
|
||
|
01:23:57.000 --> 01:23:59.000
|
||
|
Well I'm not sure a college is the right word
|
||
|
|
||
|
01:23:59.000 --> 01:24:00.000
|
||
|
though that's what I'm driving
|
||
|
|
||
|
01:24:00.000 --> 01:24:01.000
|
||
|
The reason they call it ecology
|
||
|
|
||
|
01:24:01.000 --> 01:24:03.000
|
||
|
is because it's the niche concept
|
||
|
|
||
|
01:24:03.000 --> 01:24:05.000
|
||
|
the right word that's what I'm driving
|
||
|
|
||
|
01:24:05.000 --> 01:24:06.000
|
||
|
The reason they call
|
||
|
|
||
|
01:24:06.000 --> 01:24:08.000
|
||
|
a total reduction in the amount of HPV
|
||
|
|
||
|
01:24:08.000 --> 01:24:10.000
|
||
|
Well I'm not sure a college is the right word
|
||
|
|
||
|
01:24:10.000 --> 01:24:12.000
|
||
|
It is says Alan Dove
|
||
|
|
||
|
01:24:12.000 --> 01:24:14.000
|
||
|
it is
|
||
|
|
||
|
01:24:14.000 --> 01:24:16.000
|
||
|
it's the right word
|
||
|
|
||
|
01:24:16.000 --> 01:24:18.000
|
||
|
says the guy who says he read the paper
|
||
|
|
||
|
01:24:18.000 --> 01:24:20.000
|
||
|
but didn't realize there were three vaccines
|
||
|
|
||
|
01:24:20.000 --> 01:24:22.000
|
||
|
being used in the paper
|
||
|
|
||
|
01:24:22.000 --> 01:24:24.000
|
||
|
didn't even bother to look
|
||
|
|
||
|
01:24:24.000 --> 01:24:26.000
|
||
|
or find out or notice
|
||
|
|
||
|
01:24:28.000 --> 01:24:30.000
|
||
|
never mind to think about
|
||
|
|
||
|
01:24:30.000 --> 01:24:32.000
|
||
|
what would the difference between the immune response
|
||
|
|
||
|
01:24:32.000 --> 01:24:34.000
|
||
|
of somebody who has
|
||
|
|
||
|
01:24:34.000 --> 01:24:36.000
|
||
|
immunized with one versus the other
|
||
|
|
||
|
01:24:36.000 --> 01:24:40.000
|
||
|
would one be more dangerous or less dangerous
|
||
|
|
||
|
01:24:40.000 --> 01:24:42.000
|
||
|
more immunogenic or less
|
||
|
|
||
|
01:24:42.000 --> 01:24:46.000
|
||
|
would one provoke a more specific response than the other
|
||
|
|
||
|
01:24:46.000 --> 01:24:51.000
|
||
|
does that have any impact on the ecology that he so sure is there?
|
||
|
|
||
|
01:24:51.000 --> 01:24:54.000
|
||
|
Listen to the guy in the upper right
|
||
|
|
||
|
01:24:54.000 --> 01:24:56.000
|
||
|
continue to not really understand
|
||
|
|
||
|
01:24:56.000 --> 01:24:58.000
|
||
|
why these people are being so
|
||
|
|
||
|
01:24:58.000 --> 01:25:01.000
|
||
|
imprecise with their language
|
||
|
|
||
|
01:25:01.000 --> 01:25:05.000
|
||
|
why they think it's okay to be so imprecise about
|
||
|
|
||
|
01:25:05.000 --> 01:25:07.000
|
||
|
their language
|
||
|
|
||
|
01:25:07.000 --> 01:25:09.000
|
||
|
He's not happy with it
|
||
|
|
||
|
01:25:09.000 --> 01:25:11.000
|
||
|
but he goes along with it because of the illusion of consensus
|
||
|
|
||
|
01:25:11.000 --> 01:25:13.000
|
||
|
that gets created by these kinds of discussions
|
||
|
|
||
|
01:25:13.000 --> 01:25:15.000
|
||
|
The reason they call it ecology
|
||
|
|
||
|
01:25:15.000 --> 01:25:17.000
|
||
|
is because there's the niche concept
|
||
|
|
||
|
01:25:17.000 --> 01:25:19.000
|
||
|
there's a specific niche that a virus occupies
|
||
|
|
||
|
01:25:19.000 --> 01:25:21.000
|
||
|
and if you take that virus from the niche
|
||
|
|
||
|
01:25:21.000 --> 01:25:23.000
|
||
|
something else will come in and occupy
|
||
|
|
||
|
01:25:23.000 --> 01:25:25.000
|
||
|
that's an ecological concept
|
||
|
|
||
|
01:25:25.000 --> 01:25:27.000
|
||
|
It is but it's
|
||
|
|
||
|
01:25:27.000 --> 01:25:29.000
|
||
|
I don't like the use of the term
|
||
|
|
||
|
01:25:29.000 --> 01:25:33.000
|
||
|
I don't because you're really looking at the rates of acquisition of these viruses
|
||
|
|
||
|
01:25:33.000 --> 01:25:35.000
|
||
|
the rate of acquisition
|
||
|
|
||
|
01:25:35.000 --> 01:25:37.000
|
||
|
you see he's going back to the cartoon premise
|
||
|
|
||
|
01:25:37.000 --> 01:25:39.000
|
||
|
that was set at the beginning of this discussion
|
||
|
|
||
|
01:25:39.000 --> 01:25:41.000
|
||
|
which is already lost
|
||
|
|
||
|
01:25:41.000 --> 01:25:43.000
|
||
|
because of the
|
||
|
|
||
|
01:25:43.000 --> 01:25:45.000
|
||
|
bumbling
|
||
|
|
||
|
01:25:45.000 --> 01:25:47.000
|
||
|
of these people
|
||
|
|
||
|
01:25:47.000 --> 01:25:49.000
|
||
|
but he's on it
|
||
|
|
||
|
01:25:49.000 --> 01:25:51.000
|
||
|
the guy in the upper right is on it
|
||
|
|
||
|
01:25:51.000 --> 01:25:53.000
|
||
|
we could review it right now
|
||
|
|
||
|
01:25:53.000 --> 01:25:55.000
|
||
|
let's go back Vincent
|
||
|
|
||
|
01:25:55.000 --> 01:25:57.000
|
||
|
what did you say this is? This is a
|
||
|
|
||
|
01:25:57.000 --> 01:25:59.000
|
||
|
this is a vaccine
|
||
|
|
||
|
01:25:59.000 --> 01:26:01.000
|
||
|
that is supposed to prevent the acquisition
|
||
|
|
||
|
01:26:01.000 --> 01:26:03.000
|
||
|
of human papilloma viruses
|
||
|
|
||
|
01:26:03.000 --> 01:26:05.000
|
||
|
during sexual activity
|
||
|
|
||
|
01:26:05.000 --> 01:26:07.000
|
||
|
and so it makes sense
|
||
|
|
||
|
01:26:07.000 --> 01:26:09.000
|
||
|
they're great at preventing cancer
|
||
|
|
||
|
01:26:09.000 --> 01:26:11.000
|
||
|
Vincent says
|
||
|
|
||
|
01:26:11.000 --> 01:26:13.000
|
||
|
and we should apply them to kids young
|
||
|
|
||
|
01:26:13.000 --> 01:26:15.000
|
||
|
before they acquire
|
||
|
|
||
|
01:26:15.000 --> 01:26:19.000
|
||
|
the viruses through sexual activity
|
||
|
|
||
|
01:26:19.000 --> 01:26:21.000
|
||
|
so as
|
||
|
|
||
|
01:26:21.000 --> 01:26:25.000
|
||
|
follows from that very obvious premise
|
||
|
|
||
|
01:26:25.000 --> 01:26:27.000
|
||
|
the guy up here in the upper right
|
||
|
|
||
|
01:26:27.000 --> 01:26:29.000
|
||
|
is arguing that well
|
||
|
|
||
|
01:26:29.000 --> 01:26:31.000
|
||
|
then we're looking at the rate of acquisition
|
||
|
|
||
|
01:26:31.000 --> 01:26:33.000
|
||
|
of these viruses
|
||
|
|
||
|
01:26:33.000 --> 01:26:35.000
|
||
|
that's the exact words he used
|
||
|
|
||
|
01:26:35.000 --> 01:26:37.000
|
||
|
the rate of acquisition
|
||
|
|
||
|
01:26:37.000 --> 01:26:39.000
|
||
|
we're starting from zero
|
||
|
|
||
|
01:26:39.000 --> 01:26:41.000
|
||
|
and we're acquiring viruses
|
||
|
|
||
|
01:26:41.000 --> 01:26:43.000
|
||
|
by being sexually active
|
||
|
|
||
|
01:26:43.000 --> 01:26:47.000
|
||
|
that's the cartoon premise
|
||
|
|
||
|
01:26:47.000 --> 01:26:49.000
|
||
|
and that is the cartoon premise
|
||
|
|
||
|
01:26:49.000 --> 01:26:51.000
|
||
|
under which we are supposedly
|
||
|
|
||
|
01:26:51.000 --> 01:26:53.000
|
||
|
vaccinating our teenage children
|
||
|
|
||
|
01:26:53.000 --> 01:26:57.000
|
||
|
and so inadvertently
|
||
|
|
||
|
01:26:57.000 --> 01:26:59.000
|
||
|
unwittingly this guy is actually
|
||
|
|
||
|
01:26:59.000 --> 01:27:01.000
|
||
|
questioning that premise right now
|
||
|
|
||
|
01:27:01.000 --> 01:27:03.000
|
||
|
and this guy is responding
|
||
|
|
||
|
01:27:03.000 --> 01:27:05.000
|
||
|
in a very typical
|
||
|
|
||
|
01:27:05.000 --> 01:27:07.000
|
||
|
skilled tv watcher way
|
||
|
|
||
|
01:27:07.000 --> 01:27:09.000
|
||
|
he's laughing at him
|
||
|
|
||
|
01:27:11.000 --> 01:27:13.000
|
||
|
he's making fun
|
||
|
|
||
|
01:27:13.000 --> 01:27:15.000
|
||
|
you don't like the term
|
||
|
|
||
|
01:27:15.000 --> 01:27:17.000
|
||
|
you don't like the term ecology
|
||
|
|
||
|
01:27:17.000 --> 01:27:19.000
|
||
|
you don't like the term niche
|
||
|
|
||
|
01:27:19.000 --> 01:27:21.000
|
||
|
are we being too imprecise for you
|
||
|
|
||
|
01:27:21.000 --> 01:27:25.000
|
||
|
it's wicked these ways
|
||
|
|
||
|
01:27:25.000 --> 01:27:27.000
|
||
|
ladies and gentlemen
|
||
|
|
||
|
01:27:27.000 --> 01:27:29.000
|
||
|
it is wicked these many ways
|
||
|
|
||
|
01:27:29.000 --> 01:27:31.000
|
||
|
that they haven't chanted us
|
||
|
|
||
|
01:27:31.000 --> 01:27:33.000
|
||
|
and there are many
|
||
|
|
||
|
01:27:33.000 --> 01:27:35.000
|
||
|
unwitting participants like this
|
||
|
|
||
|
01:27:35.000 --> 01:27:37.000
|
||
|
Alan Dove character down here
|
||
|
|
||
|
01:27:37.000 --> 01:27:39.000
|
||
|
who just loves to hear his own voice
|
||
|
|
||
|
01:27:39.000 --> 01:27:41.000
|
||
|
but actually doesn't know very much
|
||
|
|
||
|
01:27:41.000 --> 01:27:43.000
|
||
|
as is obvious every time he speaks
|
||
|
|
||
|
01:27:43.000 --> 01:27:45.000
|
||
|
he gets really excited
|
||
|
|
||
|
01:27:45.000 --> 01:27:47.000
|
||
|
when he thinks he's about to
|
||
|
|
||
|
01:27:47.000 --> 01:27:49.000
|
||
|
restate something
|
||
|
|
||
|
01:27:49.000 --> 01:27:51.000
|
||
|
that he sure is true
|
||
|
|
||
|
01:27:51.000 --> 01:27:53.000
|
||
|
almost like a guy who gets to run
|
||
|
|
||
|
01:27:53.000 --> 01:27:55.000
|
||
|
in a touchdown from one yard away
|
||
|
|
||
|
01:27:55.000 --> 01:27:57.000
|
||
|
it's really fun
|
||
|
|
||
|
01:27:57.000 --> 01:27:59.000
|
||
|
but it's also kind of not
|
||
|
|
||
|
01:27:59.000 --> 01:28:01.000
|
||
|
challenging if the line does their
|
||
|
|
||
|
01:28:01.000 --> 01:28:03.000
|
||
|
job and so he's always
|
||
|
|
||
|
01:28:03.000 --> 01:28:05.000
|
||
|
really excited in these discussions
|
||
|
|
||
|
01:28:05.000 --> 01:28:07.000
|
||
|
when they explain something
|
||
|
|
||
|
01:28:07.000 --> 01:28:09.000
|
||
|
and then he gets to
|
||
|
|
||
|
01:28:09.000 --> 01:28:11.000
|
||
|
explain it again because he
|
||
|
|
||
|
01:28:11.000 --> 01:28:13.000
|
||
|
thinks he understands it exactly like
|
||
|
|
||
|
01:28:13.000 --> 01:28:15.000
|
||
|
he did with the with the nine
|
||
|
|
||
|
01:28:15.000 --> 01:28:17.000
|
||
|
valent vaccine thing oh yeah they have
|
||
|
|
||
|
01:28:17.000 --> 01:28:19.000
|
||
|
a nine valent when I guess that means
|
||
|
|
||
|
01:28:19.000 --> 01:28:21.000
|
||
|
that it produces an immune response
|
||
|
|
||
|
01:28:21.000 --> 01:28:23.000
|
||
|
against a whole panel of viruses
|
||
|
|
||
|
01:28:25.000 --> 01:28:27.000
|
||
|
so here now he takes the role
|
||
|
|
||
|
01:28:27.000 --> 01:28:29.000
|
||
|
of condescension
|
||
|
|
||
|
01:28:29.000 --> 01:28:31.000
|
||
|
and says yeah you don't like the term
|
||
|
|
||
|
01:28:31.000 --> 01:28:33.000
|
||
|
well it's definitely the right term
|
||
|
|
||
|
01:28:33.000 --> 01:28:35.000
|
||
|
you don't like the term
|
||
|
|
||
|
01:28:35.000 --> 01:28:37.000
|
||
|
listen
|
||
|
|
||
|
01:28:37.000 --> 01:28:39.000
|
||
|
has this discussion spirals
|
||
|
|
||
|
01:28:39.000 --> 01:28:41.000
|
||
|
into full-on skepticism
|
||
|
|
||
|
01:28:41.000 --> 01:28:44.000
|
||
|
and Vincent is forced to just
|
||
|
|
||
|
01:28:44.000 --> 01:28:46.000
|
||
|
drag it out of the water
|
||
|
|
||
|
01:28:46.000 --> 01:28:48.000
|
||
|
you're going to exclude
|
||
|
|
||
|
01:28:48.000 --> 01:28:50.000
|
||
|
all of these others with a vaccine
|
||
|
|
||
|
01:28:50.000 --> 01:28:52.000
|
||
|
and then do the others there you're not
|
||
|
|
||
|
01:28:52.000 --> 01:28:54.000
|
||
|
vaccinating against do they come up as a result
|
||
|
|
||
|
01:28:54.000 --> 01:28:56.000
|
||
|
does the rate increase or does it not increase
|
||
|
|
||
|
01:28:56.000 --> 01:28:58.000
|
||
|
if we eradicated qlex pippians
|
||
|
|
||
|
01:28:58.000 --> 01:29:00.000
|
||
|
would other mosquitoes
|
||
|
|
||
|
01:29:00.000 --> 01:29:02.000
|
||
|
come into the niche that it occupies
|
||
|
|
||
|
01:29:02.000 --> 01:29:04.000
|
||
|
and you know become more prevalent than they are
|
||
|
|
||
|
01:29:04.000 --> 01:29:06.000
|
||
|
see he again
|
||
|
|
||
|
01:29:06.000 --> 01:29:08.000
|
||
|
completely admits that he doesn't
|
||
|
|
||
|
01:29:08.000 --> 01:29:10.000
|
||
|
understand the biological concept
|
||
|
|
||
|
01:29:10.000 --> 01:29:12.000
|
||
|
that he's arguing about
|
||
|
|
||
|
01:29:12.000 --> 01:29:14.000
|
||
|
if we get rid of a particular mosquito
|
||
|
|
||
|
01:29:14.000 --> 01:29:16.000
|
||
|
will other mosquitoes come in
|
||
|
|
||
|
01:29:16.000 --> 01:29:18.000
|
||
|
that's not exactly the same
|
||
|
|
||
|
01:29:18.000 --> 01:29:20.000
|
||
|
as sexually acquired human papillomavirus
|
||
|
|
||
|
01:29:22.000 --> 01:29:24.000
|
||
|
is it no
|
||
|
|
||
|
01:29:24.000 --> 01:29:26.000
|
||
|
and the niche that's occupied
|
||
|
|
||
|
01:29:26.000 --> 01:29:28.000
|
||
|
apparently by human papillomavirus
|
||
|
|
||
|
01:29:28.000 --> 01:29:30.000
|
||
|
it's not the same
|
||
|
|
||
|
01:29:34.000 --> 01:29:36.000
|
||
|
because a mosquito occupying a niche
|
||
|
|
||
|
01:29:36.000 --> 01:29:38.000
|
||
|
is a
|
||
|
|
||
|
01:29:38.000 --> 01:29:40.000
|
||
|
is an ecosystem
|
||
|
|
||
|
01:29:40.000 --> 01:29:42.000
|
||
|
it is a species
|
||
|
|
||
|
01:29:42.000 --> 01:29:44.000
|
||
|
it is predators
|
||
|
|
||
|
01:29:44.000 --> 01:29:46.000
|
||
|
and prey
|
||
|
|
||
|
01:29:46.000 --> 01:29:48.000
|
||
|
it's reproduction
|
||
|
|
||
|
01:29:48.000 --> 01:29:50.000
|
||
|
it's weather
|
||
|
|
||
|
01:29:50.000 --> 01:29:52.000
|
||
|
it's seasons
|
||
|
|
||
|
01:29:52.000 --> 01:29:54.000
|
||
|
it's an ecosystem
|
||
|
|
||
|
01:29:54.000 --> 01:29:56.000
|
||
|
according to the cartoon
|
||
|
|
||
|
01:29:56.000 --> 01:29:58.000
|
||
|
narrative of human papillomavirus
|
||
|
|
||
|
01:29:58.000 --> 01:30:00.000
|
||
|
human papillomavirus is something
|
||
|
|
||
|
01:30:00.000 --> 01:30:02.000
|
||
|
that you acquire when you become sexually active
|
||
|
|
||
|
01:30:02.000 --> 01:30:04.000
|
||
|
one way to avoid human papillomavirus
|
||
|
|
||
|
01:30:04.000 --> 01:30:06.000
|
||
|
would be not to be sexually active
|
||
|
|
||
|
01:30:06.000 --> 01:30:08.000
|
||
|
one way to avoid mosquitoes
|
||
|
|
||
|
01:30:08.000 --> 01:30:10.000
|
||
|
I guess is to go not go outside
|
||
|
|
||
|
01:30:10.000 --> 01:30:12.000
|
||
|
but we are not talking about
|
||
|
|
||
|
01:30:12.000 --> 01:30:14.000
|
||
|
apples and apples here
|
||
|
|
||
|
01:30:14.000 --> 01:30:16.000
|
||
|
and Alan Dove
|
||
|
|
||
|
01:30:16.000 --> 01:30:18.000
|
||
|
doesn't seem to get it yet
|
||
|
|
||
|
01:30:18.000 --> 01:30:20.000
|
||
|
and he's super confident
|
||
|
|
||
|
01:30:20.000 --> 01:30:22.000
|
||
|
that he's right because he's explaining it
|
||
|
|
||
|
01:30:22.000 --> 01:30:24.000
|
||
|
with this checkmate
|
||
|
|
||
|
01:30:24.000 --> 01:30:26.000
|
||
|
sort of
|
||
|
|
||
|
01:30:26.000 --> 01:30:28.000
|
||
|
if we got rid of one mosquito
|
||
|
|
||
|
01:30:28.000 --> 01:30:30.000
|
||
|
would another mosquito come in and do it
|
||
|
|
||
|
01:30:30.000 --> 01:30:32.000
|
||
|
please tell me that we get some
|
||
|
|
||
|
01:30:32.000 --> 01:30:34.000
|
||
|
comeback on this
|
||
|
|
||
|
01:30:34.000 --> 01:30:36.000
|
||
|
no no no I got that part
|
||
|
|
||
|
01:30:36.000 --> 01:30:38.000
|
||
|
that's an ecological question right?
|
||
|
|
||
|
01:30:38.000 --> 01:30:40.000
|
||
|
it is but I'm just
|
||
|
|
||
|
01:30:40.000 --> 01:30:42.000
|
||
|
could have simplified this a little bit by just saying
|
||
|
|
||
|
01:30:42.000 --> 01:30:44.000
|
||
|
does the rate of infection with the others go up
|
||
|
|
||
|
01:30:44.000 --> 01:30:46.000
|
||
|
in those that haven't been vaccinated
|
||
|
|
||
|
01:30:46.000 --> 01:30:48.000
|
||
|
because the ones that have been vaccinated
|
||
|
|
||
|
01:30:48.000 --> 01:30:50.000
|
||
|
have kept down the rate of infection
|
||
|
|
||
|
01:30:50.000 --> 01:30:52.000
|
||
|
with that particular species
|
||
|
|
||
|
01:30:52.000 --> 01:30:54.000
|
||
|
I mean one of the most important things
|
||
|
|
||
|
01:30:54.000 --> 01:30:56.000
|
||
|
I'm trying to drive home which I'm not doing a very good job of
|
||
|
|
||
|
01:30:56.000 --> 01:30:58.000
|
||
|
is that the biology of
|
||
|
|
||
|
01:30:58.000 --> 01:31:00.000
|
||
|
viruses
|
||
|
|
||
|
01:31:00.000 --> 01:31:02.000
|
||
|
is to a large extent
|
||
|
|
||
|
01:31:02.000 --> 01:31:04.000
|
||
|
a mythology
|
||
|
|
||
|
01:31:04.000 --> 01:31:06.000
|
||
|
and it is a mythology
|
||
|
|
||
|
01:31:06.000 --> 01:31:08.000
|
||
|
based on the false equivalence
|
||
|
|
||
|
01:31:08.000 --> 01:31:10.000
|
||
|
between replicating
|
||
|
|
||
|
01:31:10.000 --> 01:31:12.000
|
||
|
reproducing evolving species
|
||
|
|
||
|
01:31:12.000 --> 01:31:14.000
|
||
|
like a mosquito
|
||
|
|
||
|
01:31:14.000 --> 01:31:18.000
|
||
|
and an RNA signal
|
||
|
|
||
|
01:31:18.000 --> 01:31:20.000
|
||
|
an RNA noise
|
||
|
|
||
|
01:31:20.000 --> 01:31:22.000
|
||
|
an RNA phantom
|
||
|
|
||
|
01:31:22.000 --> 01:31:26.000
|
||
|
an RNA phenomenon
|
||
|
|
||
|
01:31:26.000 --> 01:31:30.000
|
||
|
and in this case a DNA phenomenon
|
||
|
|
||
|
01:31:30.000 --> 01:31:32.000
|
||
|
a genetic noise
|
||
|
|
||
|
01:31:32.000 --> 01:31:34.000
|
||
|
a genetic signal
|
||
|
|
||
|
01:31:34.000 --> 01:31:36.000
|
||
|
a genetic something
|
||
|
|
||
|
01:31:36.000 --> 01:31:38.000
|
||
|
that is not equivalent to a species
|
||
|
|
||
|
01:31:38.000 --> 01:31:40.000
|
||
|
which replicates and evolves
|
||
|
|
||
|
01:31:40.000 --> 01:31:42.000
|
||
|
and reproduces
|
||
|
|
||
|
01:31:42.000 --> 01:31:44.000
|
||
|
and is subject to selective pressures
|
||
|
|
||
|
01:31:44.000 --> 01:31:46.000
|
||
|
and predatory and prey relationships
|
||
|
|
||
|
01:31:46.000 --> 01:31:48.000
|
||
|
and the weather etc
|
||
|
|
||
|
01:31:48.000 --> 01:31:50.000
|
||
|
that false equivalence
|
||
|
|
||
|
01:31:50.000 --> 01:31:54.000
|
||
|
and this transfer of
|
||
|
|
||
|
01:31:54.000 --> 01:31:56.000
|
||
|
all of these biological ideas
|
||
|
|
||
|
01:31:56.000 --> 01:31:58.000
|
||
|
to the phenomenon
|
||
|
|
||
|
01:31:58.000 --> 01:32:02.000
|
||
|
DNA viruses is a false equivalence
|
||
|
|
||
|
01:32:02.000 --> 01:32:04.000
|
||
|
which has resulted in
|
||
|
|
||
|
01:32:04.000 --> 01:32:06.000
|
||
|
much confusion
|
||
|
|
||
|
01:32:06.000 --> 01:32:10.000
|
||
|
about the potential for viruses to evolve
|
||
|
|
||
|
01:32:10.000 --> 01:32:12.000
|
||
|
to sustain themselves
|
||
|
|
||
|
01:32:12.000 --> 01:32:14.000
|
||
|
to occupy niches
|
||
|
|
||
|
01:32:14.000 --> 01:32:16.000
|
||
|
all of these things
|
||
|
|
||
|
01:32:16.000 --> 01:32:18.000
|
||
|
are designed to bamboozle you
|
||
|
|
||
|
01:32:18.000 --> 01:32:21.000
|
||
|
into believing that many of the biological principles
|
||
|
|
||
|
01:32:21.000 --> 01:32:24.000
|
||
|
that we've come to understand our world with
|
||
|
|
||
|
01:32:24.000 --> 01:32:26.000
|
||
|
are applicable to these
|
||
|
|
||
|
01:32:26.000 --> 01:32:28.000
|
||
|
small phenomenon
|
||
|
|
||
|
01:32:28.000 --> 01:32:30.000
|
||
|
of RNA and DNA
|
||
|
|
||
|
01:32:30.000 --> 01:32:32.000
|
||
|
and they are not
|
||
|
|
||
|
01:32:32.000 --> 01:32:34.000
|
||
|
because we have a whole
|
||
|
|
||
|
01:32:34.000 --> 01:32:36.000
|
||
|
other set of biological ideas
|
||
|
|
||
|
01:32:36.000 --> 01:32:38.000
|
||
|
which describe
|
||
|
|
||
|
01:32:38.000 --> 01:32:40.000
|
||
|
the principles governing
|
||
|
|
||
|
01:32:40.000 --> 01:32:42.000
|
||
|
the behavior of RNA
|
||
|
|
||
|
01:32:42.000 --> 01:32:44.000
|
||
|
and DNA in the wild
|
||
|
|
||
|
01:32:46.000 --> 01:32:48.000
|
||
|
we understand how DNA is exchanged
|
||
|
|
||
|
01:32:48.000 --> 01:32:50.000
|
||
|
between bacteria
|
||
|
|
||
|
01:32:50.000 --> 01:32:52.000
|
||
|
we understand how DNA is exchanged
|
||
|
|
||
|
01:32:52.000 --> 01:32:54.000
|
||
|
using viruses between the roots
|
||
|
|
||
|
01:32:54.000 --> 01:32:56.000
|
||
|
of cell roots of plants
|
||
|
|
||
|
01:32:56.000 --> 01:32:58.000
|
||
|
and the fungi that grow around them
|
||
|
|
||
|
01:32:58.000 --> 01:33:00.000
|
||
|
we understand that
|
||
|
|
||
|
01:33:00.000 --> 01:33:02.000
|
||
|
the different layers
|
||
|
|
||
|
01:33:02.000 --> 01:33:04.000
|
||
|
of the phytoplankton
|
||
|
|
||
|
01:33:04.000 --> 01:33:06.000
|
||
|
in the ocean
|
||
|
|
||
|
01:33:06.000 --> 01:33:08.000
|
||
|
communicate and change
|
||
|
|
||
|
01:33:08.000 --> 01:33:10.000
|
||
|
metabolically by communicating
|
||
|
|
||
|
01:33:10.000 --> 01:33:12.000
|
||
|
with viruses
|
||
|
|
||
|
01:33:12.000 --> 01:33:14.000
|
||
|
we understand that most of our tissues
|
||
|
|
||
|
01:33:14.000 --> 01:33:16.000
|
||
|
communicate with viruses
|
||
|
|
||
|
01:33:16.000 --> 01:33:18.000
|
||
|
that are just exosomes
|
||
|
|
||
|
01:33:18.000 --> 01:33:20.000
|
||
|
and we understand
|
||
|
|
||
|
01:33:20.000 --> 01:33:22.000
|
||
|
that the replication
|
||
|
|
||
|
01:33:22.000 --> 01:33:24.000
|
||
|
of DNA and RNA is limited
|
||
|
|
||
|
01:33:24.000 --> 01:33:26.000
|
||
|
by the enzymes that are used
|
||
|
|
||
|
01:33:26.000 --> 01:33:28.000
|
||
|
in the context in which it occurs
|
||
|
|
||
|
01:33:30.000 --> 01:33:32.000
|
||
|
and these limitations
|
||
|
|
||
|
01:33:32.000 --> 01:33:34.000
|
||
|
prevent
|
||
|
|
||
|
01:33:34.000 --> 01:33:37.000
|
||
|
RNA and DNA viruses
|
||
|
|
||
|
01:33:37.000 --> 01:33:40.000
|
||
|
from reaching the level of biological phenomenon
|
||
|
|
||
|
01:33:40.000 --> 01:33:42.000
|
||
|
where terms like niche
|
||
|
|
||
|
01:33:42.000 --> 01:33:44.000
|
||
|
and ecosystem are appropriate
|
||
|
|
||
|
01:33:48.000 --> 01:33:50.000
|
||
|
that's what we're dealing with here
|
||
|
|
||
|
01:33:50.000 --> 01:33:52.000
|
||
|
and here we have
|
||
|
|
||
|
01:33:52.000 --> 01:33:54.000
|
||
|
Alan Dove so casually arguing
|
||
|
|
||
|
01:33:54.000 --> 01:33:56.000
|
||
|
that all of these things apply
|
||
|
|
||
|
01:33:56.000 --> 01:33:58.000
|
||
|
to all of these other things
|
||
|
|
||
|
01:33:58.000 --> 01:34:00.000
|
||
|
and they just don't
|
||
|
|
||
|
01:34:00.000 --> 01:34:02.000
|
||
|
and that guy up there
|
||
|
|
||
|
01:34:02.000 --> 01:34:04.000
|
||
|
at the top right seems to understand
|
||
|
|
||
|
01:34:04.000 --> 01:34:06.000
|
||
|
that there is a little bit of a contradiction
|
||
|
|
||
|
01:34:06.000 --> 01:34:08.000
|
||
|
and a little bit of
|
||
|
|
||
|
01:34:08.000 --> 01:34:10.000
|
||
|
of incongruence when you start
|
||
|
|
||
|
01:34:10.000 --> 01:34:12.000
|
||
|
to take these
|
||
|
|
||
|
01:34:12.000 --> 01:34:14.000
|
||
|
these macro-biological ideas
|
||
|
|
||
|
01:34:14.000 --> 01:34:16.000
|
||
|
and apply them to a very limited system
|
||
|
|
||
|
01:34:16.000 --> 01:34:18.000
|
||
|
like RNA or DNA viruses
|
||
|
|
||
|
01:34:18.000 --> 01:34:22.000
|
||
|
I would argue with your use of the word
|
||
|
|
||
|
01:34:22.000 --> 01:34:24.000
|
||
|
rate I think they're looking at the levels
|
||
|
|
||
|
01:34:24.000 --> 01:34:26.000
|
||
|
of the virus
|
||
|
|
||
|
01:34:26.000 --> 01:34:28.000
|
||
|
they're not looking at rates of infection
|
||
|
|
||
|
01:34:28.000 --> 01:34:30.000
|
||
|
they're looking at levels of the virus
|
||
|
|
||
|
01:34:30.000 --> 01:34:32.000
|
||
|
incidence and prevalence
|
||
|
|
||
|
01:34:32.000 --> 01:34:34.000
|
||
|
yeah it's right it's not a rate it's just
|
||
|
|
||
|
01:34:34.000 --> 01:34:36.000
|
||
|
incidence right in prevalence yeah okay so
|
||
|
|
||
|
01:34:36.000 --> 01:34:38.000
|
||
|
okay so incidents in prevalence
|
||
|
|
||
|
01:34:38.000 --> 01:34:40.000
|
||
|
and we're not looking at cancer
|
||
|
|
||
|
01:34:40.000 --> 01:34:42.000
|
||
|
and we're looking at incidents in prevalence
|
||
|
|
||
|
01:34:42.000 --> 01:34:44.000
|
||
|
without the benefit of having the
|
||
|
|
||
|
01:34:44.000 --> 01:34:46.000
|
||
|
incidents in prevalence before vaccination
|
||
|
|
||
|
01:34:46.000 --> 01:34:50.000
|
||
|
again under this cartoon assumption
|
||
|
|
||
|
01:34:50.000 --> 01:34:52.000
|
||
|
that there are no signals
|
||
|
|
||
|
01:34:52.000 --> 01:34:54.000
|
||
|
before you have sex
|
||
|
|
||
|
01:34:54.000 --> 01:34:56.000
|
||
|
and acquire these signals
|
||
|
|
||
|
01:34:58.000 --> 01:35:00.000
|
||
|
and so their entire paper in cell micro
|
||
|
|
||
|
01:35:00.000 --> 01:35:02.000
|
||
|
was based on a no data set
|
||
|
|
||
|
01:35:02.000 --> 01:35:04.000
|
||
|
at start
|
||
|
|
||
|
01:35:04.000 --> 01:35:06.000
|
||
|
at which is vaccination
|
||
|
|
||
|
01:35:06.000 --> 01:35:08.000
|
||
|
or no vaccination and then
|
||
|
|
||
|
01:35:08.000 --> 01:35:10.000
|
||
|
four years later they take their first
|
||
|
|
||
|
01:35:10.000 --> 01:35:12.000
|
||
|
measurement of the ecology
|
||
|
|
||
|
01:35:12.000 --> 01:35:14.000
|
||
|
of the human papilloma virus
|
||
|
|
||
|
01:35:14.000 --> 01:35:16.000
|
||
|
in those people
|
||
|
|
||
|
01:35:16.000 --> 01:35:18.000
|
||
|
they have no baseline
|
||
|
|
||
|
01:35:18.000 --> 01:35:20.000
|
||
|
they just assume
|
||
|
|
||
|
01:35:20.000 --> 01:35:22.000
|
||
|
like he did in the introduction
|
||
|
|
||
|
01:35:22.000 --> 01:35:24.000
|
||
|
to the paper that kids don't have
|
||
|
|
||
|
01:35:24.000 --> 01:35:26.000
|
||
|
these viruses
|
||
|
|
||
|
01:35:26.000 --> 01:35:28.000
|
||
|
and if we vaccinate them early enough
|
||
|
|
||
|
01:35:28.000 --> 01:35:30.000
|
||
|
we can stop their acquisition
|
||
|
|
||
|
01:35:30.000 --> 01:35:32.000
|
||
|
of these viruses because that's how vaccines work
|
||
|
|
||
|
01:35:36.000 --> 01:35:38.000
|
||
|
this is the illusion
|
||
|
|
||
|
01:35:38.000 --> 01:35:40.000
|
||
|
this is the mythology right here
|
||
|
|
||
|
01:35:40.000 --> 01:35:42.000
|
||
|
in front of you this is the way
|
||
|
|
||
|
01:35:42.000 --> 01:35:44.000
|
||
|
this is all they got
|
||
|
|
||
|
01:35:44.000 --> 01:35:46.000
|
||
|
and they want to vaccinate
|
||
|
|
||
|
01:35:46.000 --> 01:35:48.000
|
||
|
millions of people
|
||
|
|
||
|
01:35:48.000 --> 01:35:50.000
|
||
|
and millions of people
|
||
|
|
||
|
01:35:50.000 --> 01:35:52.000
|
||
|
millions of girls
|
||
|
|
||
|
01:35:52.000 --> 01:35:54.000
|
||
|
teenage girls
|
||
|
|
||
|
01:35:54.000 --> 01:35:56.000
|
||
|
around the world in Africa
|
||
|
|
||
|
01:35:56.000 --> 01:35:58.000
|
||
|
India America everywhere
|
||
|
|
||
|
01:35:58.000 --> 01:36:00.000
|
||
|
that will take it
|
||
|
|
||
|
01:36:00.000 --> 01:36:02.000
|
||
|
based on this flimsy
|
||
|
|
||
|
01:36:02.000 --> 01:36:04.000
|
||
|
type of discussion where
|
||
|
|
||
|
01:36:04.000 --> 01:36:06.000
|
||
|
four people apparently can read
|
||
|
|
||
|
01:36:06.000 --> 01:36:08.000
|
||
|
a paper and barely even get past the
|
||
|
|
||
|
01:36:08.000 --> 01:36:10.000
|
||
|
abstract because they're so biased
|
||
|
|
||
|
01:36:10.000 --> 01:36:12.000
|
||
|
and so bamboozled
|
||
|
|
||
|
01:36:12.000 --> 01:36:14.000
|
||
|
that they just think that
|
||
|
|
||
|
01:36:14.000 --> 01:36:16.000
|
||
|
disease means
|
||
|
|
||
|
01:36:16.000 --> 01:36:18.000
|
||
|
cure and cure is the best one
|
||
|
|
||
|
01:36:18.000 --> 01:36:20.000
|
||
|
is a vaccine
|
||
|
|
||
|
01:36:20.000 --> 01:36:22.000
|
||
|
I mean that's the foundation of their understanding
|
||
|
|
||
|
01:36:22.000 --> 01:36:24.000
|
||
|
of everything around them
|
||
|
|
||
|
01:36:24.000 --> 01:36:26.000
|
||
|
the way they put it here
|
||
|
|
||
|
01:36:26.000 --> 01:36:28.000
|
||
|
and if you look in the discussion
|
||
|
|
||
|
01:36:28.000 --> 01:36:30.000
|
||
|
they say the rationale
|
||
|
|
||
|
01:36:30.000 --> 01:36:34.000
|
||
|
for the study is that the vaccine
|
||
|
|
||
|
01:36:34.000 --> 01:36:36.000
|
||
|
reduces the number of susceptible hosts
|
||
|
|
||
|
01:36:36.000 --> 01:36:38.000
|
||
|
or the virus is targeted
|
||
|
|
||
|
01:36:38.000 --> 01:36:40.000
|
||
|
by the vaccine or
|
||
|
|
||
|
01:36:40.000 --> 01:36:42.000
|
||
|
would it favor escape
|
||
|
|
||
|
01:36:42.000 --> 01:36:44.000
|
||
|
which is the case for influenza virus
|
||
|
|
||
|
01:36:44.000 --> 01:36:46.000
|
||
|
that happens for HPV
|
||
|
|
||
|
01:36:46.000 --> 01:36:48.000
|
||
|
the idea of
|
||
|
|
||
|
01:36:48.000 --> 01:36:50.000
|
||
|
so escape mutants
|
||
|
|
||
|
01:36:50.000 --> 01:36:52.000
|
||
|
for COVID and for flu just slip that in
|
||
|
|
||
|
01:36:52.000 --> 01:36:54.000
|
||
|
there you know escape mutants
|
||
|
|
||
|
01:36:54.000 --> 01:36:56.000
|
||
|
viruses that are not targeted by the vaccine
|
||
|
|
||
|
01:36:56.000 --> 01:36:58.000
|
||
|
or would it favor escape
|
||
|
|
||
|
01:36:58.000 --> 01:37:00.000
|
||
|
which is the case for influenza virus
|
||
|
|
||
|
01:37:00.000 --> 01:37:02.000
|
||
|
that already is another mythology
|
||
|
|
||
|
01:37:02.000 --> 01:37:04.000
|
||
|
right because how would you
|
||
|
|
||
|
01:37:04.000 --> 01:37:06.000
|
||
|
and I differentiate
|
||
|
|
||
|
01:37:07.000 --> 01:37:09.000
|
||
|
let's look at the HPV example
|
||
|
|
||
|
01:37:09.000 --> 01:37:12.000
|
||
|
human papilloma virus has more than
|
||
|
|
||
|
01:37:12.000 --> 01:37:14.000
|
||
|
200 serotypes
|
||
|
|
||
|
01:37:14.000 --> 01:37:16.000
|
||
|
many of them are rare
|
||
|
|
||
|
01:37:16.000 --> 01:37:18.000
|
||
|
many of them haven't really been associated
|
||
|
|
||
|
01:37:18.000 --> 01:37:20.000
|
||
|
with cancer that we know of but how
|
||
|
|
||
|
01:37:20.000 --> 01:37:22.000
|
||
|
really have we investigated if many of them
|
||
|
|
||
|
01:37:22.000 --> 01:37:24.000
|
||
|
are spread all over the place
|
||
|
|
||
|
01:37:24.000 --> 01:37:26.000
|
||
|
geographically in space and time
|
||
|
|
||
|
01:37:26.000 --> 01:37:30.000
|
||
|
and so we vaccinate against a few of them
|
||
|
|
||
|
01:37:30.000 --> 01:37:32.000
|
||
|
we claim that it has some effect on cancer
|
||
|
|
||
|
01:37:32.000 --> 01:37:34.000
|
||
|
but we have no data for it
|
||
|
|
||
|
01:37:34.000 --> 01:37:38.000
|
||
|
and these people are now having
|
||
|
|
||
|
01:37:38.000 --> 01:37:42.000
|
||
|
creating an illusion of consensus that these things
|
||
|
|
||
|
01:37:42.000 --> 01:37:44.000
|
||
|
are obviously useful
|
||
|
|
||
|
01:37:44.000 --> 01:37:46.000
|
||
|
and that what we envision that we see in
|
||
|
|
||
|
01:37:46.000 --> 01:37:48.000
|
||
|
this paper is evidence of their usefulness
|
||
|
|
||
|
01:37:48.000 --> 01:37:50.000
|
||
|
but the evidence in this paper is
|
||
|
|
||
|
01:37:50.000 --> 01:37:52.000
|
||
|
synthetic data
|
||
|
|
||
|
01:37:52.000 --> 01:37:54.000
|
||
|
generating used a combination of
|
||
|
|
||
|
01:37:54.000 --> 01:37:56.000
|
||
|
mathematical techniques
|
||
|
|
||
|
01:37:56.000 --> 01:37:58.000
|
||
|
derived from the original data set
|
||
|
|
||
|
01:37:58.000 --> 01:38:00.000
|
||
|
which doesn't even have a baseline
|
||
|
|
||
|
01:38:00.000 --> 01:38:02.000
|
||
|
they did not measure HPV
|
||
|
|
||
|
01:38:02.000 --> 01:38:04.000
|
||
|
prevalence and serotypes
|
||
|
|
||
|
01:38:04.000 --> 01:38:06.000
|
||
|
in these children
|
||
|
|
||
|
01:38:06.000 --> 01:38:10.000
|
||
|
at vaccination
|
||
|
|
||
|
01:38:10.000 --> 01:38:12.000
|
||
|
but they tell the story here that they obviously
|
||
|
|
||
|
01:38:12.000 --> 01:38:14.000
|
||
|
they didn't have any before they started
|
||
|
|
||
|
01:38:14.000 --> 01:38:16.000
|
||
|
having sex that would be crazy
|
||
|
|
||
|
01:38:16.000 --> 01:38:18.000
|
||
|
these are sexually transmitted viruses
|
||
|
|
||
|
01:38:18.000 --> 01:38:22.000
|
||
|
what a magnificently huge assumption
|
||
|
|
||
|
01:38:22.000 --> 01:38:26.000
|
||
|
it's very convenient
|
||
|
|
||
|
01:38:26.000 --> 01:38:28.000
|
||
|
for the vaccine maker
|
||
|
|
||
|
01:38:28.000 --> 01:38:30.000
|
||
|
very convenient that these guys don't ever
|
||
|
|
||
|
01:38:30.000 --> 01:38:34.000
|
||
|
even notice it
|
||
|
|
||
|
01:38:34.000 --> 01:38:36.000
|
||
|
like how can they not notice it if
|
||
|
|
||
|
01:38:36.000 --> 01:38:38.000
|
||
|
there's no baseline
|
||
|
|
||
|
01:38:38.000 --> 01:38:40.000
|
||
|
like what kind of study was this
|
||
|
|
||
|
01:38:44.000 --> 01:38:46.000
|
||
|
that happens for HPV
|
||
|
|
||
|
01:38:46.000 --> 01:38:48.000
|
||
|
but the idea of reducing the
|
||
|
|
||
|
01:38:48.000 --> 01:38:50.000
|
||
|
number of susceptible hosts
|
||
|
|
||
|
01:38:50.000 --> 01:38:52.000
|
||
|
may increase the likelihood of type replacement
|
||
|
|
||
|
01:38:52.000 --> 01:38:54.000
|
||
|
which is what they call it
|
||
|
|
||
|
01:38:54.000 --> 01:38:56.000
|
||
|
the paper before this though
|
||
|
|
||
|
01:38:56.000 --> 01:38:58.000
|
||
|
even the use of hosts
|
||
|
|
||
|
01:38:58.000 --> 01:39:02.000
|
||
|
susceptible hosts
|
||
|
|
||
|
01:39:02.000 --> 01:39:06.000
|
||
|
reducing the number of susceptible hosts
|
||
|
|
||
|
01:39:06.000 --> 01:39:08.000
|
||
|
implies parasite
|
||
|
|
||
|
01:39:08.000 --> 01:39:12.000
|
||
|
implies parasite
|
||
|
|
||
|
01:39:12.000 --> 01:39:16.000
|
||
|
is a virus a parasite
|
||
|
|
||
|
01:39:16.000 --> 01:39:18.000
|
||
|
should we think of it as a parasite
|
||
|
|
||
|
01:39:18.000 --> 01:39:20.000
|
||
|
or is that a biological term
|
||
|
|
||
|
01:39:20.000 --> 01:39:22.000
|
||
|
that's inappropriate to use for
|
||
|
|
||
|
01:39:22.000 --> 01:39:26.000
|
||
|
an RNA or DNA phenomena
|
||
|
|
||
|
01:39:26.000 --> 01:39:28.000
|
||
|
I would argue that it's part of this
|
||
|
|
||
|
01:39:28.000 --> 01:39:30.000
|
||
|
semantic war
|
||
|
|
||
|
01:39:30.000 --> 01:39:34.000
|
||
|
that's obfuscating
|
||
|
|
||
|
01:39:34.000 --> 01:39:36.000
|
||
|
the limitations
|
||
|
|
||
|
01:39:36.000 --> 01:39:38.000
|
||
|
of RNA and DNA
|
||
|
|
||
|
01:39:38.000 --> 01:39:40.000
|
||
|
virology
|
||
|
|
||
|
01:39:40.000 --> 01:39:42.000
|
||
|
and perpetuating
|
||
|
|
||
|
01:39:42.000 --> 01:39:44.000
|
||
|
this mythology that
|
||
|
|
||
|
01:39:44.000 --> 01:39:46.000
|
||
|
pandemics are possible
|
||
|
|
||
|
01:39:46.000 --> 01:39:48.000
|
||
|
that public health is necessary
|
||
|
|
||
|
01:39:48.000 --> 01:39:52.000
|
||
|
that vaccines are essential
|
||
|
|
||
|
01:39:52.000 --> 01:39:55.000
|
||
|
and slowly but surely
|
||
|
|
||
|
01:39:55.000 --> 01:39:57.000
|
||
|
old guys and young guys
|
||
|
|
||
|
01:39:57.000 --> 01:39:59.000
|
||
|
and old ladies and young ladies
|
||
|
|
||
|
01:39:59.000 --> 01:40:01.000
|
||
|
are going to have to realize in their own
|
||
|
|
||
|
01:40:01.000 --> 01:40:03.000
|
||
|
time and in their own way
|
||
|
|
||
|
01:40:03.000 --> 01:40:05.000
|
||
|
that this is
|
||
|
|
||
|
01:40:05.000 --> 01:40:07.000
|
||
|
a lie
|
||
|
|
||
|
01:40:07.000 --> 01:40:09.000
|
||
|
maybe this guy's learning it
|
||
|
|
||
|
01:40:09.000 --> 01:40:11.000
|
||
|
slowly but surely right now
|
||
|
|
||
|
01:40:11.000 --> 01:40:13.000
|
||
|
it will die still just confused
|
||
|
|
||
|
01:40:13.000 --> 01:40:15.000
|
||
|
I think a lot of people are
|
||
|
|
||
|
01:40:15.000 --> 01:40:17.000
|
||
|
going to die just confused
|
||
|
|
||
|
01:40:17.000 --> 01:40:19.000
|
||
|
clearly stated that there were some geographic
|
||
|
|
||
|
01:40:19.000 --> 01:40:21.000
|
||
|
differences in distribution of the SARS virus
|
||
|
|
||
|
01:40:21.000 --> 01:40:23.000
|
||
|
rather geographic distribution
|
||
|
|
||
|
01:40:23.000 --> 01:40:25.000
|
||
|
differences with these SARS types
|
||
|
|
||
|
01:40:25.000 --> 01:40:27.000
|
||
|
that's a good question
|
||
|
|
||
|
01:40:27.000 --> 01:40:29.000
|
||
|
if there's none there to begin with
|
||
|
|
||
|
01:40:29.000 --> 01:40:31.000
|
||
|
and you've cut out all of the ones
|
||
|
|
||
|
01:40:31.000 --> 01:40:33.000
|
||
|
that you're worried about causing cancer
|
||
|
|
||
|
01:40:33.000 --> 01:40:35.000
|
||
|
then nothing is going to come in to replace it
|
||
|
|
||
|
01:40:35.000 --> 01:40:37.000
|
||
|
because it's not there
|
||
|
|
||
|
01:40:37.000 --> 01:40:39.000
|
||
|
this particular study is in Sweden
|
||
|
|
||
|
01:40:39.000 --> 01:40:41.000
|
||
|
so they're not looking at a global
|
||
|
|
||
|
01:40:41.000 --> 01:40:43.000
|
||
|
perspective there
|
||
|
|
||
|
01:40:43.000 --> 01:40:45.000
|
||
|
but it's an interesting question
|
||
|
|
||
|
01:40:45.000 --> 01:40:47.000
|
||
|
do you see a different pattern elsewhere
|
||
|
|
||
|
01:40:47.000 --> 01:40:49.000
|
||
|
okay I'm sorry to
|
||
|
|
||
|
01:40:49.000 --> 01:40:51.000
|
||
|
I'm sorry
|
||
|
|
||
|
01:40:51.000 --> 01:40:53.000
|
||
|
people will allow it for this
|
||
|
|
||
|
01:40:53.000 --> 01:40:55.000
|
||
|
I'm not sure I can't
|
||
|
|
||
|
01:40:55.000 --> 01:40:57.000
|
||
|
so what are you doing this paper as they look at
|
||
|
|
||
|
01:40:57.000 --> 01:40:59.000
|
||
|
community level occurrence of different types
|
||
|
|
||
|
01:40:59.000 --> 01:41:01.000
|
||
|
up to eight years after vaccination
|
||
|
|
||
|
01:41:01.000 --> 01:41:03.000
|
||
|
either in girls only or gender neutral
|
||
|
|
||
|
01:41:03.000 --> 01:41:05.000
|
||
|
so one or the other
|
||
|
|
||
|
01:41:05.000 --> 01:41:07.000
|
||
|
right so they actually have three different
|
||
|
|
||
|
01:41:07.000 --> 01:41:09.000
|
||
|
communities that they're looking at there
|
||
|
|
||
|
01:41:09.000 --> 01:41:11.000
|
||
|
some that didn't have vaccination campaign
|
||
|
|
||
|
01:41:11.000 --> 01:41:13.000
|
||
|
some that targeted girls specifically
|
||
|
|
||
|
01:41:13.000 --> 01:41:15.000
|
||
|
because it's a very effective way to control the virus
|
||
|
|
||
|
01:41:15.000 --> 01:41:17.000
|
||
|
or at least it should be and then others that were
|
||
|
|
||
|
01:41:17.000 --> 01:41:19.000
|
||
|
gender neutral boys and girls got vaccinated
|
||
|
|
||
|
01:41:19.000 --> 01:41:21.000
|
||
|
and we should say there has been previous evidence that
|
||
|
|
||
|
01:41:21.000 --> 01:41:23.000
|
||
|
vaccination is changing the
|
||
|
|
||
|
01:41:23.000 --> 01:41:25.000
|
||
|
the prevalence of genotypes
|
||
|
|
||
|
01:41:25.000 --> 01:41:27.000
|
||
|
right there these the ones targeted by the vaccines
|
||
|
|
||
|
01:41:27.000 --> 01:41:29.000
|
||
|
are going down and
|
||
|
|
||
|
01:41:29.000 --> 01:41:31.000
|
||
|
so the question is are the others that are not targeted
|
||
|
|
||
|
01:41:31.000 --> 01:41:33.000
|
||
|
going up or are they staying the same?
|
||
|
|
||
|
01:41:33.000 --> 01:41:35.000
|
||
|
that's what they're addressing
|
||
|
|
||
|
01:41:35.000 --> 01:41:37.000
|
||
|
so none of these
|
||
|
|
||
|
01:41:37.000 --> 01:41:39.000
|
||
|
the conclusions that he just listed
|
||
|
|
||
|
01:41:39.000 --> 01:41:41.000
|
||
|
were actually reached using the data
|
||
|
|
||
|
01:41:41.000 --> 01:41:43.000
|
||
|
and the data in this paper
|
||
|
|
||
|
01:41:43.000 --> 01:41:45.000
|
||
|
were unable to say any of those things
|
||
|
|
||
|
01:41:45.000 --> 01:41:47.000
|
||
|
but the combination
|
||
|
|
||
|
01:41:47.000 --> 01:41:49.000
|
||
|
of a
|
||
|
|
||
|
01:41:49.000 --> 01:41:51.000
|
||
|
linear modeling and a
|
||
|
|
||
|
01:41:51.000 --> 01:41:53.000
|
||
|
what is it?
|
||
|
|
||
|
01:41:53.000 --> 01:41:55.000
|
||
|
graphical something
|
||
|
|
||
|
01:41:55.000 --> 01:41:57.000
|
||
|
something network
|
||
|
|
||
|
01:41:57.000 --> 01:41:59.000
|
||
|
two different types of
|
||
|
|
||
|
01:41:59.000 --> 01:42:01.000
|
||
|
math were used to
|
||
|
|
||
|
01:42:01.000 --> 01:42:03.000
|
||
|
synthetically generate
|
||
|
|
||
|
01:42:03.000 --> 01:42:05.000
|
||
|
finally to comprehensive
|
||
|
|
||
|
01:42:05.000 --> 01:42:07.000
|
||
|
evaluate the community level
|
||
|
|
||
|
01:42:07.000 --> 01:42:09.000
|
||
|
HPV type diversity
|
||
|
|
||
|
01:42:09.000 --> 01:42:11.000
|
||
|
distribution between the trial arms
|
||
|
|
||
|
01:42:11.000 --> 01:42:13.000
|
||
|
we applied
|
||
|
|
||
|
01:42:13.000 --> 01:42:15.000
|
||
|
gen modeling
|
||
|
|
||
|
01:42:15.000 --> 01:42:17.000
|
||
|
for the observed HPV type prevalence data
|
||
|
|
||
|
01:42:17.000 --> 01:42:19.000
|
||
|
and generated a synthetic data set
|
||
|
|
||
|
01:42:19.000 --> 01:42:21.000
|
||
|
from each original community
|
||
|
|
||
|
01:42:21.000 --> 01:42:23.000
|
||
|
randomized trial arm
|
||
|
|
||
|
01:42:23.000 --> 01:42:25.000
|
||
|
first the gen model
|
||
|
|
||
|
01:42:25.000 --> 01:42:27.000
|
||
|
was fitted to each
|
||
|
|
||
|
01:42:27.000 --> 01:42:29.000
|
||
|
observed trial arm HPV type
|
||
|
|
||
|
01:42:29.000 --> 01:42:31.000
|
||
|
distribution over time
|
||
|
|
||
|
01:42:31.000 --> 01:42:33.000
|
||
|
from which a synthetic
|
||
|
|
||
|
01:42:33.000 --> 01:42:35.000
|
||
|
HPV type prevalence distribution
|
||
|
|
||
|
01:42:35.000 --> 01:42:37.000
|
||
|
for 100,000 individuals
|
||
|
|
||
|
01:42:37.000 --> 01:42:39.000
|
||
|
was simulated
|
||
|
|
||
|
01:42:39.000 --> 01:42:43.000
|
||
|
for each arm and time point
|
||
|
|
||
|
01:42:43.000 --> 01:42:45.000
|
||
|
for community level alpha
|
||
|
|
||
|
01:42:45.000 --> 01:42:47.000
|
||
|
and beta diversity estimation
|
||
|
|
||
|
01:42:47.000 --> 01:42:49.000
|
||
|
synthetic HPV type prevalence
|
||
|
|
||
|
01:42:49.000 --> 01:42:51.000
|
||
|
distribution for each trial arm
|
||
|
|
||
|
01:42:51.000 --> 01:42:53.000
|
||
|
data with an n equals
|
||
|
|
||
|
01:42:53.000 --> 01:42:55.000
|
||
|
100,000 was randomly resampled
|
||
|
|
||
|
01:42:55.000 --> 01:42:57.000
|
||
|
a thousand times without replacement
|
||
|
|
||
|
01:42:57.000 --> 01:42:59.000
|
||
|
for equal community size
|
||
|
|
||
|
01:42:59.000 --> 01:43:01.000
|
||
|
community level HPV type
|
||
|
|
||
|
01:43:01.000 --> 01:43:03.000
|
||
|
alpha diversity was estimated using
|
||
|
|
||
|
01:43:03.000 --> 01:43:05.000
|
||
|
resampled synthetic communities
|
||
|
|
||
|
01:43:05.000 --> 01:43:07.000
|
||
|
for 18 to 22 year olds
|
||
|
|
||
|
01:43:07.000 --> 01:43:09.000
|
||
|
a significant increase
|
||
|
|
||
|
01:43:09.000 --> 01:43:11.000
|
||
|
in alpha diversity
|
||
|
|
||
|
01:43:11.000 --> 01:43:13.000
|
||
|
the Shannon index was observed
|
||
|
|
||
|
01:43:13.000 --> 01:43:15.000
|
||
|
from 18 to 22 year olds
|
||
|
|
||
|
01:43:15.000 --> 01:43:17.000
|
||
|
in the synthetic and gender
|
||
|
|
||
|
01:43:17.000 --> 01:43:19.000
|
||
|
and neutral communities
|
||
|
|
||
|
01:43:19.000 --> 01:43:21.000
|
||
|
in contrast a significantly lower
|
||
|
|
||
|
01:43:21.000 --> 01:43:23.000
|
||
|
alpha diversity was sustained
|
||
|
|
||
|
01:43:23.000 --> 01:43:25.000
|
||
|
in the synthetic girls-only communities
|
||
|
|
||
|
01:43:25.000 --> 01:43:27.000
|
||
|
among the 22 year olds
|
||
|
|
||
|
01:43:27.000 --> 01:43:29.000
|
||
|
does that sound like data
|
||
|
|
||
|
01:43:29.000 --> 01:43:31.000
|
||
|
which leads you to believe
|
||
|
|
||
|
01:43:31.000 --> 01:43:35.000
|
||
|
what Vincent just said
|
||
|
|
||
|
01:43:35.000 --> 01:43:37.000
|
||
|
or does it sound like they did a
|
||
|
|
||
|
01:43:37.000 --> 01:43:39.000
|
||
|
mathematical simulation
|
||
|
|
||
|
01:43:39.000 --> 01:43:41.000
|
||
|
that gave them the result that they wanted
|
||
|
|
||
|
01:43:41.000 --> 01:43:45.000
|
||
|
and how
|
||
|
|
||
|
01:43:45.000 --> 01:43:47.000
|
||
|
disingenuously
|
||
|
|
||
|
01:43:47.000 --> 01:43:49.000
|
||
|
is this result
|
||
|
|
||
|
01:43:49.000 --> 01:43:51.000
|
||
|
or this result set
|
||
|
|
||
|
01:43:51.000 --> 01:43:53.000
|
||
|
being represented by these people
|
||
|
|
||
|
01:43:53.000 --> 01:43:55.000
|
||
|
they haven't even mentioned
|
||
|
|
||
|
01:43:55.000 --> 01:43:58.000
|
||
|
that general linearized models
|
||
|
|
||
|
01:43:58.000 --> 01:44:01.000
|
||
|
and this technique called
|
||
|
|
||
|
01:44:01.000 --> 01:44:03.000
|
||
|
a graphical-independent
|
||
|
|
||
|
01:44:03.000 --> 01:44:05.000
|
||
|
network model
|
||
|
|
||
|
01:44:05.000 --> 01:44:09.000
|
||
|
a graphical-independent
|
||
|
|
||
|
01:44:09.000 --> 01:44:11.000
|
||
|
network model
|
||
|
|
||
|
01:44:11.000 --> 01:44:13.000
|
||
|
a graphical-independent
|
||
|
|
||
|
01:44:13.000 --> 01:44:15.000
|
||
|
network modeling
|
||
|
|
||
|
01:44:15.000 --> 01:44:19.000
|
||
|
was used for the observed HPV type
|
||
|
|
||
|
01:44:19.000 --> 01:44:21.000
|
||
|
prevalence data
|
||
|
|
||
|
01:44:21.000 --> 01:44:23.000
|
||
|
and generated a synthetic dataset
|
||
|
|
||
|
01:44:23.000 --> 01:44:25.000
|
||
|
from each original community
|
||
|
|
||
|
01:44:25.000 --> 01:44:27.000
|
||
|
randomized trial arm
|
||
|
|
||
|
01:44:27.000 --> 01:44:29.000
|
||
|
first the
|
||
|
|
||
|
01:44:29.000 --> 01:44:31.000
|
||
|
gin model was fitted
|
||
|
|
||
|
01:44:31.000 --> 01:44:33.000
|
||
|
to each observed trial arm
|
||
|
|
||
|
01:44:33.000 --> 01:44:35.000
|
||
|
HPV type distribution
|
||
|
|
||
|
01:44:35.000 --> 01:44:37.000
|
||
|
over time
|
||
|
|
||
|
01:44:37.000 --> 01:44:39.000
|
||
|
from which a synthetic
|
||
|
|
||
|
01:44:39.000 --> 01:44:41.000
|
||
|
so they basically used
|
||
|
|
||
|
01:44:41.000 --> 01:44:43.000
|
||
|
linear
|
||
|
|
||
|
01:44:43.000 --> 01:44:45.000
|
||
|
and
|
||
|
|
||
|
01:44:45.000 --> 01:44:47.000
|
||
|
graphical
|
||
|
|
||
|
01:44:47.000 --> 01:44:49.000
|
||
|
independence network models
|
||
|
|
||
|
01:44:49.000 --> 01:44:51.000
|
||
|
which I don't say that I understand
|
||
|
|
||
|
01:44:51.000 --> 01:44:53.000
|
||
|
but I'm just telling you what they're doing
|
||
|
|
||
|
01:44:53.000 --> 01:44:55.000
|
||
|
and what they say in their paper
|
||
|
|
||
|
01:44:55.000 --> 01:44:57.000
|
||
|
and what they say in their paper to generate
|
||
|
|
||
|
01:44:57.000 --> 01:44:59.000
|
||
|
a synthetic dataset
|
||
|
|
||
|
01:44:59.000 --> 01:45:01.000
|
||
|
made up of 100,000
|
||
|
|
||
|
01:45:01.000 --> 01:45:03.000
|
||
|
synthetic cases
|
||
|
|
||
|
01:45:03.000 --> 01:45:05.000
|
||
|
or distributions of the
|
||
|
|
||
|
01:45:05.000 --> 01:45:07.000
|
||
|
Hylun papilloma virus
|
||
|
|
||
|
01:45:07.000 --> 01:45:09.000
|
||
|
serotypes
|
||
|
|
||
|
01:45:09.000 --> 01:45:11.000
|
||
|
and in those
|
||
|
|
||
|
01:45:11.000 --> 01:45:13.000
|
||
|
communities which were simulated
|
||
|
|
||
|
01:45:13.000 --> 01:45:15.000
|
||
|
they say that they got
|
||
|
|
||
|
01:45:15.000 --> 01:45:17.000
|
||
|
a significantly lower
|
||
|
|
||
|
01:45:17.000 --> 01:45:19.000
|
||
|
alpha diversity
|
||
|
|
||
|
01:45:19.000 --> 01:45:21.000
|
||
|
in the girls-only communities
|
||
|
|
||
|
01:45:21.000 --> 01:45:23.000
|
||
|
and the gender-neutral
|
||
|
|
||
|
01:45:23.000 --> 01:45:25.000
|
||
|
communities of some kind.
|
||
|
|
||
|
01:45:25.000 --> 01:45:27.000
|
||
|
I mean
|
||
|
|
||
|
01:45:27.000 --> 01:45:29.000
|
||
|
the way that they are discussing this
|
||
|
|
||
|
01:45:29.000 --> 01:45:31.000
|
||
|
it sounds like they just measured a bunch
|
||
|
|
||
|
01:45:31.000 --> 01:45:33.000
|
||
|
of people and found a change in the viruses
|
||
|
|
||
|
01:45:33.000 --> 01:45:35.000
|
||
|
but they actually didn't
|
||
|
|
||
|
01:45:35.000 --> 01:45:37.000
|
||
|
they measured a bunch of people
|
||
|
|
||
|
01:45:37.000 --> 01:45:39.000
|
||
|
and then they used a lot of mathematical tricks
|
||
|
|
||
|
01:45:39.000 --> 01:45:41.000
|
||
|
and tools to create
|
||
|
|
||
|
01:45:41.000 --> 01:45:43.000
|
||
|
a dataset where they say that
|
||
|
|
||
|
01:45:43.000 --> 01:45:45.000
|
||
|
they found a difference between these different
|
||
|
|
||
|
01:45:45.000 --> 01:45:47.000
|
||
|
communities but they're all synthetic communities
|
||
|
|
||
|
01:45:49.000 --> 01:45:51.000
|
||
|
they don't have enough data from the
|
||
|
|
||
|
01:45:51.000 --> 01:45:53.000
|
||
|
real data because what?
|
||
|
|
||
|
01:45:53.000 --> 01:45:55.000
|
||
|
because the communities they're discussing
|
||
|
|
||
|
01:45:55.000 --> 01:45:57.000
|
||
|
have a vaccination rate of between
|
||
|
|
||
|
01:45:57.000 --> 01:45:59.000
|
||
|
25 and 50 percent
|
||
|
|
||
|
01:46:03.000 --> 01:46:05.000
|
||
|
Did you hear that from Vincent or any of these guys yet?
|
||
|
|
||
|
01:46:05.000 --> 01:46:07.000
|
||
|
Not at all
|
||
|
|
||
|
01:46:07.000 --> 01:46:09.000
|
||
|
Not at all
|
||
|
|
||
|
01:46:09.000 --> 01:46:11.000
|
||
|
You don't hear
|
||
|
|
||
|
01:46:11.000 --> 01:46:13.000
|
||
|
it from them at all
|
||
|
|
||
|
01:46:13.000 --> 01:46:15.000
|
||
|
because they don't understand the paper
|
||
|
|
||
|
01:46:15.000 --> 01:46:17.000
|
||
|
or they haven't read the paper
|
||
|
|
||
|
01:46:17.000 --> 01:46:19.000
|
||
|
or they've read the paper and don't understand it
|
||
|
|
||
|
01:46:19.000 --> 01:46:21.000
|
||
|
they're actually all
|
||
|
|
||
|
01:46:21.000 --> 01:46:23.000
|
||
|
based on synthetic modeling
|
||
|
|
||
|
01:46:23.000 --> 01:46:25.000
|
||
|
and interpretation
|
||
|
|
||
|
01:46:25.000 --> 01:46:27.000
|
||
|
based on the limited data set
|
||
|
|
||
|
01:46:27.000 --> 01:46:29.000
|
||
|
that they had
|
||
|
|
||
|
01:46:29.000 --> 01:46:31.000
|
||
|
that the limited data set that they had
|
||
|
|
||
|
01:46:31.000 --> 01:46:33.000
|
||
|
was insufficient to show
|
||
|
|
||
|
01:46:33.000 --> 01:46:35.000
|
||
|
any effect at all
|
||
|
|
||
|
01:46:35.000 --> 01:46:37.000
|
||
|
is lost on these guys
|
||
|
|
||
|
01:46:41.000 --> 01:46:43.000
|
||
|
That's the best way to put it
|
||
|
|
||
|
01:46:43.000 --> 01:46:45.000
|
||
|
That's exactly right
|
||
|
|
||
|
01:46:45.000 --> 01:46:47.000
|
||
|
So they first look at four years
|
||
|
|
||
|
01:46:47.000 --> 01:46:49.000
|
||
|
after vaccination and they compare
|
||
|
|
||
|
01:46:49.000 --> 01:46:51.000
|
||
|
HPV types in this community
|
||
|
|
||
|
01:46:51.000 --> 01:46:53.000
|
||
|
and they have a
|
||
|
|
||
|
01:46:53.000 --> 01:46:55.000
|
||
|
generalized linear model
|
||
|
|
||
|
01:46:55.000 --> 01:46:57.000
|
||
|
GLM for looking at this
|
||
|
|
||
|
01:46:57.000 --> 01:46:59.000
|
||
|
these are all statistical analyses
|
||
|
|
||
|
01:46:59.000 --> 01:47:01.000
|
||
|
of course
|
||
|
|
||
|
01:47:01.000 --> 01:47:03.000
|
||
|
No differences in the
|
||
|
|
||
|
01:47:03.000 --> 01:47:05.000
|
||
|
between the gender-neutral arm A and girls-only-arm B
|
||
|
|
||
|
01:47:05.000 --> 01:47:07.000
|
||
|
at the community or type level
|
||
|
|
||
|
01:47:07.000 --> 01:47:09.000
|
||
|
which remained true even after selecting
|
||
|
|
||
|
01:47:09.000 --> 01:47:11.000
|
||
|
certain birth cohorts
|
||
|
|
||
|
01:47:11.000 --> 01:47:13.000
|
||
|
for the strongest difference in strength
|
||
|
|
||
|
01:47:13.000 --> 01:47:15.000
|
||
|
but four years post-vaccination
|
||
|
|
||
|
01:47:15.000 --> 01:47:17.000
|
||
|
and epigenicity of vaccine-targeted genotypes
|
||
|
|
||
|
01:47:17.000 --> 01:47:19.000
|
||
|
that would be 16, 18, 31
|
||
|
|
||
|
01:47:19.000 --> 01:47:21.000
|
||
|
and 45, 45 in both gender-neutral communities
|
||
|
|
||
|
01:47:21.000 --> 01:47:23.000
|
||
|
and for girls-only communities
|
||
|
|
||
|
01:47:23.000 --> 01:47:25.000
|
||
|
so reduction in the
|
||
|
|
||
|
01:47:25.000 --> 01:47:27.000
|
||
|
circulation of those types
|
||
|
|
||
|
01:47:27.000 --> 01:47:29.000
|
||
|
if you will
|
||
|
|
||
|
01:47:29.000 --> 01:47:31.000
|
||
|
So I have another question related to that then
|
||
|
|
||
|
01:47:31.000 --> 01:47:33.000
|
||
|
How long does the vaccine protect?
|
||
|
|
||
|
01:47:33.000 --> 01:47:35.000
|
||
|
Well we've looked
|
||
|
|
||
|
01:47:35.000 --> 01:47:37.000
|
||
|
when was this first
|
||
|
|
||
|
01:47:37.000 --> 01:47:39.000
|
||
|
This group is from 92 at the earliest
|
||
|
|
||
|
01:47:39.000 --> 01:47:41.000
|
||
|
as far as I know it's durable
|
||
|
|
||
|
01:47:41.000 --> 01:47:43.000
|
||
|
I haven't heard anything about
|
||
|
|
||
|
01:47:43.000 --> 01:47:45.000
|
||
|
waning immunity against it
|
||
|
|
||
|
01:47:45.000 --> 01:47:47.000
|
||
|
because it's not a molecular
|
||
|
|
||
|
01:47:47.000 --> 01:47:49.000
|
||
|
vaccine dependent on the genome
|
||
|
|
||
|
01:47:49.000 --> 01:47:51.000
|
||
|
it's a protein vaccine
|
||
|
|
||
|
01:47:51.000 --> 01:47:53.000
|
||
|
The eight years post-vaccination they found comparable to portions of these
|
||
|
|
||
|
01:47:53.000 --> 01:47:55.000
|
||
|
vaccine-targeted types
|
||
|
|
||
|
01:47:55.000 --> 01:47:57.000
|
||
|
16, 18, 31, 45, again
|
||
|
|
||
|
01:47:57.000 --> 01:47:59.000
|
||
|
in general-neutral and then they find 16, 18, 31
|
||
|
|
||
|
01:47:59.000 --> 01:48:01.000
|
||
|
are reduced in the girls-only communities
|
||
|
|
||
|
01:48:01.000 --> 01:48:03.000
|
||
|
so those are
|
||
|
|
||
|
01:48:03.000 --> 01:48:05.000
|
||
|
types that are targeted by the vaccine
|
||
|
|
||
|
01:48:05.000 --> 01:48:07.000
|
||
|
you can see a reduction which has been reported elsewhere
|
||
|
|
||
|
01:48:07.000 --> 01:48:09.000
|
||
|
Now eight years post-vaccination
|
||
|
|
||
|
01:48:09.000 --> 01:48:11.000
|
||
|
they found an increase of non-vaccinated
|
||
|
|
||
|
01:48:11.000 --> 01:48:13.000
|
||
|
and non-vaccinated types
|
||
|
|
||
|
01:48:13.000 --> 01:48:15.000
|
||
|
52 and 66
|
||
|
|
||
|
01:48:15.000 --> 01:48:17.000
|
||
|
exclusively among the gender-neutral communities
|
||
|
|
||
|
01:48:17.000 --> 01:48:19.000
|
||
|
when you compare them with the control
|
||
|
|
||
|
01:48:19.000 --> 01:48:21.000
|
||
|
because we didn't get any vaccine
|
||
|
|
||
|
01:48:21.000 --> 01:48:23.000
|
||
|
so 52 and 66 are not in the vaccine
|
||
|
|
||
|
01:48:23.000 --> 01:48:25.000
|
||
|
but they're going up
|
||
|
|
||
|
01:48:25.000 --> 01:48:27.000
|
||
|
but you don't see that in the girls-only
|
||
|
|
||
|
01:48:27.000 --> 01:48:29.000
|
||
|
comparison
|
||
|
|
||
|
01:48:29.000 --> 01:48:31.000
|
||
|
I don't know why that is
|
||
|
|
||
|
01:48:31.000 --> 01:48:33.000
|
||
|
I got to this part in the paper
|
||
|
|
||
|
01:48:33.000 --> 01:48:35.000
|
||
|
I was like wait
|
||
|
|
||
|
01:48:35.000 --> 01:48:37.000
|
||
|
how do we make sense of this
|
||
|
|
||
|
01:48:37.000 --> 01:48:39.000
|
||
|
and eventually what I kind of
|
||
|
|
||
|
01:48:39.000 --> 01:48:41.000
|
||
|
like partly from the data but also just like
|
||
|
|
||
|
01:48:41.000 --> 01:48:43.000
|
||
|
how would that even work
|
||
|
|
||
|
01:48:43.000 --> 01:48:45.000
|
||
|
is that the unvaccinated boys
|
||
|
|
||
|
01:48:45.000 --> 01:48:47.000
|
||
|
may serve as something of a reservoir
|
||
|
|
||
|
01:48:47.000 --> 01:48:49.000
|
||
|
for some of the
|
||
|
|
||
|
01:48:49.000 --> 01:48:51.000
|
||
|
of the HPV 16, 18 at all
|
||
|
|
||
|
01:48:51.000 --> 01:48:53.000
|
||
|
and that is preventing
|
||
|
|
||
|
01:48:53.000 --> 01:48:55.000
|
||
|
the
|
||
|
|
||
|
01:48:55.000 --> 01:48:57.000
|
||
|
the ingress if you will of
|
||
|
|
||
|
01:48:57.000 --> 01:48:59.000
|
||
|
52 and 66
|
||
|
|
||
|
01:48:59.000 --> 01:49:01.000
|
||
|
because the niche is not completely unoccupied
|
||
|
|
||
|
01:49:01.000 --> 01:49:03.000
|
||
|
there's a segment of the population that still has
|
||
|
|
||
|
01:49:03.000 --> 01:49:05.000
|
||
|
these oncogenic viruses
|
||
|
|
||
|
01:49:05.000 --> 01:49:07.000
|
||
|
Now that's pretty funny
|
||
|
|
||
|
01:49:07.000 --> 01:49:09.000
|
||
|
for him to say because
|
||
|
|
||
|
01:49:09.000 --> 01:49:11.000
|
||
|
again it seems like
|
||
|
|
||
|
01:49:11.000 --> 01:49:13.000
|
||
|
he hasn't read the paper well enough to know
|
||
|
|
||
|
01:49:13.000 --> 01:49:15.000
|
||
|
that the simulated communities
|
||
|
|
||
|
01:49:15.000 --> 01:49:17.000
|
||
|
have a coverage of 25 to 50 percent
|
||
|
|
||
|
01:49:17.000 --> 01:49:19.000
|
||
|
at best
|
||
|
|
||
|
01:49:19.000 --> 01:49:21.000
|
||
|
and he hasn't realized
|
||
|
|
||
|
01:49:21.000 --> 01:49:23.000
|
||
|
that they don't have a baseline
|
||
|
|
||
|
01:49:23.000 --> 01:49:27.000
|
||
|
so they have no idea
|
||
|
|
||
|
01:49:27.000 --> 01:49:29.000
|
||
|
what the distribution of these
|
||
|
|
||
|
01:49:29.000 --> 01:49:31.000
|
||
|
viruses and serotypes was
|
||
|
|
||
|
01:49:31.000 --> 01:49:33.000
|
||
|
in the background before the
|
||
|
|
||
|
01:49:33.000 --> 01:49:35.000
|
||
|
vaccination took place
|
||
|
|
||
|
01:49:35.000 --> 01:49:37.000
|
||
|
and he's working under the assumption
|
||
|
|
||
|
01:49:37.000 --> 01:49:39.000
|
||
|
that again
|
||
|
|
||
|
01:49:39.000 --> 01:49:41.000
|
||
|
the girls are clean and the boys are clean
|
||
|
|
||
|
01:49:41.000 --> 01:49:43.000
|
||
|
and then they are vaccinated
|
||
|
|
||
|
01:49:43.000 --> 01:49:45.000
|
||
|
and then they mix together sexually
|
||
|
|
||
|
01:49:45.000 --> 01:49:47.000
|
||
|
and then the boys
|
||
|
|
||
|
01:49:47.000 --> 01:49:49.000
|
||
|
if they're not vaccinated
|
||
|
|
||
|
01:49:49.000 --> 01:49:51.000
|
||
|
are the reservoirs
|
||
|
|
||
|
01:49:51.000 --> 01:49:53.000
|
||
|
from which these girls are getting the virus
|
||
|
|
||
|
01:49:53.000 --> 01:49:55.000
|
||
|
but again we're talking about
|
||
|
|
||
|
01:49:55.000 --> 01:49:57.000
|
||
|
vaccination penetration rate
|
||
|
|
||
|
01:49:57.000 --> 01:49:59.000
|
||
|
of like less than 50 percent
|
||
|
|
||
|
01:49:59.000 --> 01:50:03.000
|
||
|
so all the ideas that they're working with
|
||
|
|
||
|
01:50:03.000 --> 01:50:05.000
|
||
|
all the assumptions that they're working with
|
||
|
|
||
|
01:50:05.000 --> 01:50:07.000
|
||
|
are cartoon simple
|
||
|
|
||
|
01:50:07.000 --> 01:50:09.000
|
||
|
cartoon simple
|
||
|
|
||
|
01:50:09.000 --> 01:50:11.000
|
||
|
in the face
|
||
|
|
||
|
01:50:11.000 --> 01:50:13.000
|
||
|
of the paper
|
||
|
|
||
|
01:50:13.000 --> 01:50:15.000
|
||
|
which admits that the
|
||
|
|
||
|
01:50:15.000 --> 01:50:17.000
|
||
|
cartoon simple doesn't work here
|
||
|
|
||
|
01:50:17.000 --> 01:50:19.000
|
||
|
because we're not even able to test that
|
||
|
|
||
|
01:50:19.000 --> 01:50:21.000
|
||
|
there are hundreds
|
||
|
|
||
|
01:50:21.000 --> 01:50:23.000
|
||
|
of serotypes we only test
|
||
|
|
||
|
01:50:23.000 --> 01:50:25.000
|
||
|
for a few
|
||
|
|
||
|
01:50:25.000 --> 01:50:27.000
|
||
|
for 10
|
||
|
|
||
|
01:50:27.000 --> 01:50:29.000
|
||
|
and we look at how these 10 change
|
||
|
|
||
|
01:50:29.000 --> 01:50:31.000
|
||
|
even though we vaccinate from between
|
||
|
|
||
|
01:50:31.000 --> 01:50:33.000
|
||
|
two and nine
|
||
|
|
||
|
01:50:33.000 --> 01:50:35.000
|
||
|
a total number of
|
||
|
|
||
|
01:50:35.000 --> 01:50:37.000
|
||
|
serotypes
|
||
|
|
||
|
01:50:37.000 --> 01:50:39.000
|
||
|
and it gets worse
|
||
|
|
||
|
01:50:39.000 --> 01:50:41.000
|
||
|
the guy up here
|
||
|
|
||
|
01:50:41.000 --> 01:50:43.000
|
||
|
is about to drop the bomb
|
||
|
|
||
|
01:50:43.000 --> 01:50:45.000
|
||
|
of wait a minute
|
||
|
|
||
|
01:50:45.000 --> 01:50:47.000
|
||
|
virology is supposed to be like this
|
||
|
|
||
|
01:50:47.000 --> 01:50:49.000
|
||
|
virology is supposed to be like this
|
||
|
|
||
|
01:50:49.000 --> 01:50:51.000
|
||
|
so what does this mean?
|
||
|
|
||
|
01:50:51.000 --> 01:50:53.000
|
||
|
and they have no clue because
|
||
|
|
||
|
01:50:53.000 --> 01:50:55.000
|
||
|
again this is immunomethology
|
||
|
|
||
|
01:50:55.000 --> 01:50:57.000
|
||
|
the high fidelity is a lie
|
||
|
|
||
|
01:50:57.000 --> 01:50:59.000
|
||
|
the deep
|
||
|
|
||
|
01:50:59.000 --> 01:51:03.000
|
||
|
in depth understanding is a lie
|
||
|
|
||
|
01:51:03.000 --> 01:51:05.000
|
||
|
the application of all of these
|
||
|
|
||
|
01:51:05.000 --> 01:51:07.000
|
||
|
complicated biological
|
||
|
|
||
|
01:51:07.000 --> 01:51:09.000
|
||
|
phenomenon that apply to species
|
||
|
|
||
|
01:51:09.000 --> 01:51:11.000
|
||
|
in evolution
|
||
|
|
||
|
01:51:11.000 --> 01:51:13.000
|
||
|
in ecosystems and applying it to
|
||
|
|
||
|
01:51:13.000 --> 01:51:15.000
|
||
|
virus and virus phenomenon
|
||
|
|
||
|
01:51:15.000 --> 01:51:17.000
|
||
|
is a lie
|
||
|
|
||
|
01:51:19.000 --> 01:51:21.000
|
||
|
that's the dissonance that you see
|
||
|
|
||
|
01:51:21.000 --> 01:51:23.000
|
||
|
this guy dealing with
|
||
|
|
||
|
01:51:23.000 --> 01:51:25.000
|
||
|
in real time
|
||
|
|
||
|
01:51:25.000 --> 01:51:27.000
|
||
|
as he realizes that a lot of this
|
||
|
|
||
|
01:51:27.000 --> 01:51:29.000
|
||
|
mythology
|
||
|
|
||
|
01:51:29.000 --> 01:51:31.000
|
||
|
has been proven wrong
|
||
|
|
||
|
01:51:31.000 --> 01:51:33.000
|
||
|
a lot of these assumptions
|
||
|
|
||
|
01:51:33.000 --> 01:51:35.000
|
||
|
that his career is based
|
||
|
|
||
|
01:51:35.000 --> 01:51:37.000
|
||
|
on have been proven wrong
|
||
|
|
||
|
01:51:37.000 --> 01:51:39.000
|
||
|
are being proven wrong
|
||
|
|
||
|
01:51:39.000 --> 01:51:41.000
|
||
|
in real time
|
||
|
|
||
|
01:51:41.000 --> 01:51:43.000
|
||
|
the HPV vaccine
|
||
|
|
||
|
01:51:43.000 --> 01:51:45.000
|
||
|
doesn't work like the polio vaccine
|
||
|
|
||
|
01:51:45.000 --> 01:51:47.000
|
||
|
did when this guy was a kid
|
||
|
|
||
|
01:51:47.000 --> 01:51:49.000
|
||
|
it doesn't work like the measles
|
||
|
|
||
|
01:51:49.000 --> 01:51:51.000
|
||
|
vaccine works like this
|
||
|
|
||
|
01:51:51.000 --> 01:51:53.000
|
||
|
guy was a kid
|
||
|
|
||
|
01:51:53.000 --> 01:51:55.000
|
||
|
it just doesn't
|
||
|
|
||
|
01:51:55.000 --> 01:51:57.000
|
||
|
work like the vaccine of a
|
||
|
|
||
|
01:51:57.000 --> 01:51:59.000
|
||
|
self-limiting disease
|
||
|
|
||
|
01:51:59.000 --> 01:52:01.000
|
||
|
for which natural immunity
|
||
|
|
||
|
01:52:01.000 --> 01:52:03.000
|
||
|
can be formed by infection
|
||
|
|
||
|
01:52:03.000 --> 01:52:07.000
|
||
|
and if there were ever
|
||
|
|
||
|
01:52:07.000 --> 01:52:09.000
|
||
|
any working examples of a
|
||
|
|
||
|
01:52:09.000 --> 01:52:11.000
|
||
|
vaccine that was successful
|
||
|
|
||
|
01:52:11.000 --> 01:52:13.000
|
||
|
it would be a vaccine made
|
||
|
|
||
|
01:52:13.000 --> 01:52:15.000
|
||
|
from an attenuated
|
||
|
|
||
|
01:52:15.000 --> 01:52:17.000
|
||
|
virus a chemically weakened
|
||
|
|
||
|
01:52:17.000 --> 01:52:19.000
|
||
|
virus
|
||
|
|
||
|
01:52:19.000 --> 01:52:21.000
|
||
|
and exposure to it at a
|
||
|
|
||
|
01:52:21.000 --> 01:52:23.000
|
||
|
barrier
|
||
|
|
||
|
01:52:23.000 --> 01:52:25.000
|
||
|
that intramuscular
|
||
|
|
||
|
01:52:25.000 --> 01:52:27.000
|
||
|
injection of it
|
||
|
|
||
|
01:52:27.000 --> 01:52:29.000
|
||
|
or that in a combination
|
||
|
|
||
|
01:52:29.000 --> 01:52:31.000
|
||
|
of adjuvant substances
|
||
|
|
||
|
01:52:31.000 --> 01:52:33.000
|
||
|
no, no, no
|
||
|
|
||
|
01:52:33.000 --> 01:52:35.000
|
||
|
an Allen Dove
|
||
|
|
||
|
01:52:35.000 --> 01:52:37.000
|
||
|
is not going to realize it
|
||
|
|
||
|
01:52:37.000 --> 01:52:39.000
|
||
|
in his lifetime
|
||
|
|
||
|
01:52:39.000 --> 01:52:41.000
|
||
|
he is a skilled TV watcher
|
||
|
|
||
|
01:52:41.000 --> 01:52:43.000
|
||
|
until the last person around him
|
||
|
|
||
|
01:52:43.000 --> 01:52:45.000
|
||
|
comes to this conclusion
|
||
|
|
||
|
01:52:45.000 --> 01:52:47.000
|
||
|
he will live in this boat
|
||
|
|
||
|
01:52:47.000 --> 01:52:49.000
|
||
|
they're not spreading them to the girls
|
||
|
|
||
|
01:52:49.000 --> 01:52:51.000
|
||
|
who got vaccinated
|
||
|
|
||
|
01:52:51.000 --> 01:52:53.000
|
||
|
but, you know, that's my theory
|
||
|
|
||
|
01:52:53.000 --> 01:52:55.000
|
||
|
that's not really something that the data speak to
|
||
|
|
||
|
01:52:55.000 --> 01:52:57.000
|
||
|
but I think that's at least gave me
|
||
|
|
||
|
01:52:57.000 --> 01:52:59.000
|
||
|
a little explanation that could work
|
||
|
|
||
|
01:52:59.000 --> 01:53:01.000
|
||
|
so that means
|
||
|
|
||
|
01:53:01.000 --> 01:53:03.000
|
||
|
the ones that got vaccinated
|
||
|
|
||
|
01:53:03.000 --> 01:53:05.000
|
||
|
are they still susceptible to the one
|
||
|
|
||
|
01:53:05.000 --> 01:53:07.000
|
||
|
the strains that were not included in the vaccine, right?
|
||
|
|
||
|
01:53:07.000 --> 01:53:09.000
|
||
|
did they convert?
|
||
|
|
||
|
01:53:09.000 --> 01:53:11.000
|
||
|
do they look at that?
|
||
|
|
||
|
01:53:11.000 --> 01:53:13.000
|
||
|
let's see, the analysis is
|
||
|
|
||
|
01:53:13.000 --> 01:53:15.000
|
||
|
let's look at the methods, hang on
|
||
|
|
||
|
01:53:15.000 --> 01:53:17.000
|
||
|
methods except the document
|
||
|
|
||
|
01:53:17.000 --> 01:53:19.000
|
||
|
is this serology or
|
||
|
|
||
|
01:53:19.000 --> 01:53:21.000
|
||
|
well, people infected with
|
||
|
|
||
|
01:53:21.000 --> 01:53:23.000
|
||
|
any of the HPV's
|
||
|
|
||
|
01:53:23.000 --> 01:53:25.000
|
||
|
don't they eventually develop antibodies
|
||
|
|
||
|
01:53:25.000 --> 01:53:27.000
|
||
|
but the antibodies aren't protective
|
||
|
|
||
|
01:53:27.000 --> 01:53:29.000
|
||
|
because the genome is already inside
|
||
|
|
||
|
01:53:29.000 --> 01:53:31.000
|
||
|
holding up like a plasmid in cells
|
||
|
|
||
|
01:53:31.000 --> 01:53:33.000
|
||
|
or is that, did I just remember that
|
||
|
|
||
|
01:53:33.000 --> 01:53:35.000
|
||
|
Sarah prevalence, yeah, that's how they look here
|
||
|
|
||
|
01:53:35.000 --> 01:53:37.000
|
||
|
we're looking at antibodies to the different types
|
||
|
|
||
|
01:53:37.000 --> 01:53:39.000
|
||
|
so if you have antibodies to 16
|
||
|
|
||
|
01:53:39.000 --> 01:53:41.000
|
||
|
you're not protected against any of the other types
|
||
|
|
||
|
01:53:41.000 --> 01:53:43.000
|
||
|
so I wonder
|
||
|
|
||
|
01:53:43.000 --> 01:53:45.000
|
||
|
if you actually caught that
|
||
|
|
||
|
01:53:45.000 --> 01:53:47.000
|
||
|
well, I didn't realize I was an onscreen
|
||
|
|
||
|
01:53:47.000 --> 01:53:49.000
|
||
|
so Alan Dove
|
||
|
|
||
|
01:53:49.000 --> 01:53:51.000
|
||
|
basically again just drops the ball
|
||
|
|
||
|
01:53:51.000 --> 01:53:53.000
|
||
|
and admits that he doesn't know anything about
|
||
|
|
||
|
01:53:53.000 --> 01:53:55.000
|
||
|
what he's talking about
|
||
|
|
||
|
01:53:55.000 --> 01:53:57.000
|
||
|
but he's trying to pretend that he's in authority
|
||
|
|
||
|
01:53:57.000 --> 01:53:59.000
|
||
|
and this guy up here
|
||
|
|
||
|
01:53:59.000 --> 01:54:01.000
|
||
|
is still having problems with the idea that
|
||
|
|
||
|
01:54:01.000 --> 01:54:03.000
|
||
|
wait, there are really a lot of
|
||
|
|
||
|
01:54:03.000 --> 01:54:05.000
|
||
|
serotypes
|
||
|
|
||
|
01:54:05.000 --> 01:54:07.000
|
||
|
and we're only vaccinating against a few of them
|
||
|
|
||
|
01:54:07.000 --> 01:54:09.000
|
||
|
so you guys are talking about ecology
|
||
|
|
||
|
01:54:09.000 --> 01:54:11.000
|
||
|
you're predicting an outcome
|
||
|
|
||
|
01:54:11.000 --> 01:54:13.000
|
||
|
and did they see this outcome?
|
||
|
|
||
|
01:54:13.000 --> 01:54:15.000
|
||
|
and the reality is
|
||
|
|
||
|
01:54:15.000 --> 01:54:17.000
|
||
|
is that they are still trying to read the paper
|
||
|
|
||
|
01:54:17.000 --> 01:54:19.000
|
||
|
in real time to find out exactly
|
||
|
|
||
|
01:54:19.000 --> 01:54:21.000
|
||
|
how this outcome was reached
|
||
|
|
||
|
01:54:21.000 --> 01:54:23.000
|
||
|
and they still haven't gotten to the paragraph
|
||
|
|
||
|
01:54:23.000 --> 01:54:25.000
|
||
|
that I read to you earlier
|
||
|
|
||
|
01:54:25.000 --> 01:54:27.000
|
||
|
where they say
|
||
|
|
||
|
01:54:27.000 --> 01:54:29.000
|
||
|
that the way that they reach these conclusions
|
||
|
|
||
|
01:54:29.000 --> 01:54:31.000
|
||
|
is by creating a synthetic data set
|
||
|
|
||
|
01:54:31.000 --> 01:54:33.000
|
||
|
that was at least 10 times larger
|
||
|
|
||
|
01:54:33.000 --> 01:54:35.000
|
||
|
than the original data set from which it was derived
|
||
|
|
||
|
01:54:39.000 --> 01:54:41.000
|
||
|
I would ask, if they haven't asked
|
||
|
|
||
|
01:54:41.000 --> 01:54:43.000
|
||
|
the people who were protected against the cancer
|
||
|
|
||
|
01:54:43.000 --> 01:54:45.000
|
||
|
inducing strains of HPV
|
||
|
|
||
|
01:54:45.000 --> 01:54:47.000
|
||
|
were still susceptible to the none
|
||
|
|
||
|
01:54:47.000 --> 01:54:49.000
|
||
|
cancer-producing HPV?
|
||
|
|
||
|
01:54:49.000 --> 01:54:51.000
|
||
|
did they convert or not?
|
||
|
|
||
|
01:54:51.000 --> 01:54:53.000
|
||
|
No, they didn't because the ones
|
||
|
|
||
|
01:54:53.000 --> 01:54:55.000
|
||
|
in these cohorts that were vaccinated against the cancer-causing types
|
||
|
|
||
|
01:54:55.000 --> 01:54:57.000
|
||
|
they saw an increase in
|
||
|
|
||
|
01:54:57.000 --> 01:54:59.000
|
||
|
seroconversion against the ones that were not in the vaccine
|
||
|
|
||
|
01:54:59.000 --> 01:55:01.000
|
||
|
so they're clearly getting infected because they're making input
|
||
|
|
||
|
01:55:01.000 --> 01:55:03.000
|
||
|
Right, so they do, they seroconvert against
|
||
|
|
||
|
01:55:03.000 --> 01:55:05.000
|
||
|
the ones that were not in the vaccine against 52 and 66
|
||
|
|
||
|
01:55:05.000 --> 01:55:07.000
|
||
|
they don't seroconvert against 16 and 18
|
||
|
|
||
|
01:55:07.000 --> 01:55:09.000
|
||
|
that weren't in the vaccine
|
||
|
|
||
|
01:55:09.000 --> 01:55:11.000
|
||
|
if they weren't vaccinated
|
||
|
|
||
|
01:55:11.000 --> 01:55:13.000
|
||
|
Does that make sense?
|
||
|
|
||
|
01:55:13.000 --> 01:55:15.000
|
||
|
You get the vaccine, you're going to have antibodies to those
|
||
|
|
||
|
01:55:15.000 --> 01:55:17.000
|
||
|
I'm not sure how they sorted the two out
|
||
|
|
||
|
01:55:17.000 --> 01:55:19.000
|
||
|
but obviously there's a way to do it
|
||
|
|
||
|
01:55:19.000 --> 01:55:21.000
|
||
|
Let's look
|
||
|
|
||
|
01:55:21.000 --> 01:55:23.000
|
||
|
if you want to say 16 and 18
|
||
|
|
||
|
01:55:23.000 --> 01:55:25.000
|
||
|
is declining in prevalence
|
||
|
|
||
|
01:55:25.000 --> 01:55:27.000
|
||
|
based on serology
|
||
|
|
||
|
01:55:27.000 --> 01:55:29.000
|
||
|
that means that
|
||
|
|
||
|
01:55:29.000 --> 01:55:31.000
|
||
|
you're getting contracted antibodies
|
||
|
|
||
|
01:55:31.000 --> 01:55:33.000
|
||
|
naturally, so that's
|
||
|
|
||
|
01:55:33.000 --> 01:55:35.000
|
||
|
even if you've been immunized with 16 and 18
|
||
|
|
||
|
01:55:35.000 --> 01:55:37.000
|
||
|
and eventually those antibodies will go down
|
||
|
|
||
|
01:55:37.000 --> 01:55:39.000
|
||
|
unless you're re-infected, those antibodies will go down
|
||
|
|
||
|
01:55:39.000 --> 01:55:41.000
|
||
|
unless circulation of those types
|
||
|
|
||
|
01:55:41.000 --> 01:55:43.000
|
||
|
whereas you see higher levels of antibodies against the non-vaccine
|
||
|
|
||
|
01:55:43.000 --> 01:55:45.000
|
||
|
included types than you're saying
|
||
|
|
||
|
01:55:45.000 --> 01:55:47.000
|
||
|
those are circulating in the community and they're infecting our subjects
|
||
|
|
||
|
01:55:47.000 --> 01:55:49.000
|
||
|
That's right, but they're not
|
||
|
|
||
|
01:55:49.000 --> 01:55:51.000
|
||
|
It's really unbelievable, right?
|
||
|
|
||
|
01:55:51.000 --> 01:55:53.000
|
||
|
This contradiction and this
|
||
|
|
||
|
01:55:53.000 --> 01:55:55.000
|
||
|
this doesn't
|
||
|
|
||
|
01:55:55.000 --> 01:55:57.000
|
||
|
compute to any of the people on the screen
|
||
|
|
||
|
01:55:57.000 --> 01:55:59.000
|
||
|
and they're still just trying to rationalize it
|
||
|
|
||
|
01:55:59.000 --> 01:56:01.000
|
||
|
making sense
|
||
|
|
||
|
01:56:01.000 --> 01:56:03.000
|
||
|
Let me reiterate
|
||
|
|
||
|
01:56:03.000 --> 01:56:07.000
|
||
|
They use seroprevalence to decide whether or not these people have been infected by these
|
||
|
|
||
|
01:56:07.000 --> 01:56:09.000
|
||
|
of HPV
|
||
|
|
||
|
01:56:11.000 --> 01:56:13.000
|
||
|
but the vaccine
|
||
|
|
||
|
01:56:13.000 --> 01:56:15.000
|
||
|
the only way they can measure
|
||
|
|
||
|
01:56:15.000 --> 01:56:17.000
|
||
|
whether or not the vaccine works
|
||
|
|
||
|
01:56:17.000 --> 01:56:19.000
|
||
|
is looking for seroprevalence responses
|
||
|
|
||
|
01:56:19.000 --> 01:56:21.000
|
||
|
to the vaccine
|
||
|
|
||
|
01:56:21.000 --> 01:56:23.000
|
||
|
So the assumption
|
||
|
|
||
|
01:56:23.000 --> 01:56:25.000
|
||
|
is that if they vaccinate you against
|
||
|
|
||
|
01:56:25.000 --> 01:56:27.000
|
||
|
9 serotypes of HPV
|
||
|
|
||
|
01:56:27.000 --> 01:56:29.000
|
||
|
that you will have
|
||
|
|
||
|
01:56:29.000 --> 01:56:31.000
|
||
|
9 different antibodies
|
||
|
|
||
|
01:56:31.000 --> 01:56:33.000
|
||
|
in circulation responding to
|
||
|
|
||
|
01:56:33.000 --> 01:56:37.000
|
||
|
those 9 different serotypes of HPV
|
||
|
|
||
|
01:56:37.000 --> 01:56:41.000
|
||
|
but then when they look for seroprevalence for
|
||
|
|
||
|
01:56:41.000 --> 01:56:43.000
|
||
|
against all of these viruses
|
||
|
|
||
|
01:56:43.000 --> 01:56:47.000
|
||
|
they find a decreased seroprevalence to
|
||
|
|
||
|
01:56:47.000 --> 01:56:49.000
|
||
|
the viruses
|
||
|
|
||
|
01:56:49.000 --> 01:56:51.000
|
||
|
that you were vaccinated to and an increased
|
||
|
|
||
|
01:56:51.000 --> 01:56:53.000
|
||
|
seroprevalence to the
|
||
|
|
||
|
01:56:53.000 --> 01:56:55.000
|
||
|
to the viruses which are present
|
||
|
|
||
|
01:56:55.000 --> 01:56:57.000
|
||
|
in those people
|
||
|
|
||
|
01:56:57.000 --> 01:56:59.000
|
||
|
So they use the signal
|
||
|
|
||
|
01:56:59.000 --> 01:57:01.000
|
||
|
for immunity
|
||
|
|
||
|
01:57:01.000 --> 01:57:05.000
|
||
|
to also indicate the presence of the virus
|
||
|
|
||
|
01:57:07.000 --> 01:57:09.000
|
||
|
which is really quite
|
||
|
|
||
|
01:57:09.000 --> 01:57:11.000
|
||
|
extraordinary
|
||
|
|
||
|
01:57:11.000 --> 01:57:13.000
|
||
|
They don't have
|
||
|
|
||
|
01:57:13.000 --> 01:57:15.000
|
||
|
actually any data according to their read
|
||
|
|
||
|
01:57:15.000 --> 01:57:17.000
|
||
|
on the prevalence of
|
||
|
|
||
|
01:57:17.000 --> 01:57:19.000
|
||
|
viruses. They have
|
||
|
|
||
|
01:57:19.000 --> 01:57:21.000
|
||
|
data on the prevalence of
|
||
|
|
||
|
01:57:21.000 --> 01:57:23.000
|
||
|
seroprevalence to
|
||
|
|
||
|
01:57:23.000 --> 01:57:25.000
|
||
|
particular serotypes
|
||
|
|
||
|
01:57:25.000 --> 01:57:27.000
|
||
|
of human papilloma virus
|
||
|
|
||
|
01:57:27.000 --> 01:57:29.000
|
||
|
and they only have
|
||
|
|
||
|
01:57:29.000 --> 01:57:31.000
|
||
|
the capability of testing for about
|
||
|
|
||
|
01:57:31.000 --> 01:57:33.000
|
||
|
10 of those
|
||
|
|
||
|
01:57:33.000 --> 01:57:37.000
|
||
|
conditions
|
||
|
|
||
|
01:57:37.000 --> 01:57:39.000
|
||
|
And so they're just kind of casually laughing
|
||
|
|
||
|
01:57:39.000 --> 01:57:41.000
|
||
|
about how I wonder how they differentiate
|
||
|
|
||
|
01:57:41.000 --> 01:57:43.000
|
||
|
between antibodies from the vaccine
|
||
|
|
||
|
01:57:43.000 --> 01:57:45.000
|
||
|
and antibodies from exposure to
|
||
|
|
||
|
01:57:45.000 --> 01:57:47.000
|
||
|
the types that they're trying to eliminate
|
||
|
|
||
|
01:57:47.000 --> 01:57:49.000
|
||
|
Can they tell the difference between
|
||
|
|
||
|
01:57:49.000 --> 01:57:51.000
|
||
|
them? I guess they must have been able to
|
||
|
|
||
|
01:57:51.000 --> 01:57:53.000
|
||
|
let's read about it. They must have done it
|
||
|
|
||
|
01:57:53.000 --> 01:57:55.000
|
||
|
somewhere and then they never come to a conclusion
|
||
|
|
||
|
01:57:55.000 --> 01:57:57.000
|
||
|
and Alan Dubbs fine with that
|
||
|
|
||
|
01:57:57.000 --> 01:57:59.000
|
||
|
They're not causing cancer
|
||
|
|
||
|
01:57:59.000 --> 01:58:01.000
|
||
|
They're not causing cancer
|
||
|
|
||
|
01:58:01.000 --> 01:58:03.000
|
||
|
unless you're re-infected
|
||
|
|
||
|
01:58:03.000 --> 01:58:05.000
|
||
|
those antibodies will go down and that will
|
||
|
|
||
|
01:58:05.000 --> 01:58:07.000
|
||
|
support your idea that there's less circulation
|
||
|
|
||
|
01:58:07.000 --> 01:58:09.000
|
||
|
of those types
|
||
|
|
||
|
01:58:09.000 --> 01:58:11.000
|
||
|
and whereas you see higher levels of antibodies
|
||
|
|
||
|
01:58:11.000 --> 01:58:13.000
|
||
|
against the non-vaccine included types
|
||
|
|
||
|
01:58:13.000 --> 01:58:15.000
|
||
|
than you're saying those are circulating in the community
|
||
|
|
||
|
01:58:15.000 --> 01:58:17.000
|
||
|
and they're infecting our subjects
|
||
|
|
||
|
01:58:17.000 --> 01:58:19.000
|
||
|
But they're not causing cancer
|
||
|
|
||
|
01:58:19.000 --> 01:58:21.000
|
||
|
They're not causing cancer
|
||
|
|
||
|
01:58:21.000 --> 01:58:23.000
|
||
|
They're not causing cancer
|
||
|
|
||
|
01:58:23.000 --> 01:58:25.000
|
||
|
That's the question
|
||
|
|
||
|
01:58:25.000 --> 01:58:27.000
|
||
|
The assumption is
|
||
|
|
||
|
01:58:27.000 --> 01:58:29.000
|
||
|
that any data
|
||
|
|
||
|
01:58:29.000 --> 01:58:31.000
|
||
|
that they have
|
||
|
|
||
|
01:58:31.000 --> 01:58:33.000
|
||
|
on these particular
|
||
|
|
||
|
01:58:33.000 --> 01:58:35.000
|
||
|
serotypes
|
||
|
|
||
|
01:58:35.000 --> 01:58:37.000
|
||
|
is real
|
||
|
|
||
|
01:58:37.000 --> 01:58:39.000
|
||
|
That's the assumption
|
||
|
|
||
|
01:58:39.000 --> 01:58:41.000
|
||
|
It's the assumption
|
||
|
|
||
|
01:58:41.000 --> 01:58:43.000
|
||
|
that's made on all of these papers
|
||
|
|
||
|
01:58:43.000 --> 01:58:45.000
|
||
|
all of the time
|
||
|
|
||
|
01:58:45.000 --> 01:58:47.000
|
||
|
is that
|
||
|
|
||
|
01:58:47.000 --> 01:58:49.000
|
||
|
the distribution
|
||
|
|
||
|
01:58:49.000 --> 01:58:51.000
|
||
|
of the variable in question
|
||
|
|
||
|
01:58:51.000 --> 01:58:53.000
|
||
|
obviously must be this
|
||
|
|
||
|
01:58:53.000 --> 01:58:57.000
|
||
|
So if we don't find what we expect
|
||
|
|
||
|
01:58:57.000 --> 01:58:59.000
|
||
|
then obviously
|
||
|
|
||
|
01:58:59.000 --> 01:59:01.000
|
||
|
what we find is a result of
|
||
|
|
||
|
01:59:01.000 --> 01:59:03.000
|
||
|
the manipulation that we made
|
||
|
|
||
|
01:59:03.000 --> 01:59:07.000
|
||
|
and what none of these biologists and what
|
||
|
|
||
|
01:59:07.000 --> 01:59:09.000
|
||
|
so many academic biologists
|
||
|
|
||
|
01:59:09.000 --> 01:59:11.000
|
||
|
are trained not to do
|
||
|
|
||
|
01:59:11.000 --> 01:59:13.000
|
||
|
is to wonder
|
||
|
|
||
|
01:59:13.000 --> 01:59:17.000
|
||
|
too long about what the initial condition really was
|
||
|
|
||
|
01:59:17.000 --> 01:59:19.000
|
||
|
To assume
|
||
|
|
||
|
01:59:19.000 --> 01:59:21.000
|
||
|
that the initial condition is something
|
||
|
|
||
|
01:59:21.000 --> 01:59:23.000
|
||
|
that you could imagine
|
||
|
|
||
|
01:59:23.000 --> 01:59:25.000
|
||
|
like the initial condition of these children
|
||
|
|
||
|
01:59:25.000 --> 01:59:27.000
|
||
|
well obviously
|
||
|
|
||
|
01:59:27.000 --> 01:59:29.000
|
||
|
since these are sexually transmitted viruses
|
||
|
|
||
|
01:59:29.000 --> 01:59:31.000
|
||
|
and these are kids
|
||
|
|
||
|
01:59:31.000 --> 01:59:33.000
|
||
|
in their early teens
|
||
|
|
||
|
01:59:33.000 --> 01:59:35.000
|
||
|
that haven't had sex
|
||
|
|
||
|
01:59:35.000 --> 01:59:37.000
|
||
|
obviously they have no HPV
|
||
|
|
||
|
01:59:37.000 --> 01:59:39.000
|
||
|
viruses and no HPV
|
||
|
|
||
|
01:59:39.000 --> 01:59:41.000
|
||
|
seroprevalence
|
||
|
|
||
|
01:59:41.000 --> 01:59:43.000
|
||
|
detectable by our tests
|
||
|
|
||
|
01:59:43.000 --> 01:59:45.000
|
||
|
So we don't need to test them
|
||
|
|
||
|
01:59:45.000 --> 01:59:47.000
|
||
|
on the day that we vaccinate them
|
||
|
|
||
|
01:59:47.000 --> 01:59:49.000
|
||
|
We'll test them four years later
|
||
|
|
||
|
01:59:49.000 --> 01:59:53.000
|
||
|
and none of these biologists
|
||
|
|
||
|
01:59:53.000 --> 01:59:55.000
|
||
|
are sophisticated enough
|
||
|
|
||
|
01:59:55.000 --> 01:59:57.000
|
||
|
except for maybe the guy in the upper right
|
||
|
|
||
|
01:59:57.000 --> 01:59:59.000
|
||
|
to understand how ridiculously
|
||
|
|
||
|
01:59:59.000 --> 02:00:01.000
|
||
|
inaccurate
|
||
|
|
||
|
02:00:01.000 --> 02:00:03.000
|
||
|
and unscientific it would be
|
||
|
|
||
|
02:00:03.000 --> 02:00:05.000
|
||
|
to claim that the data that you
|
||
|
|
||
|
02:00:05.000 --> 02:00:07.000
|
||
|
collect at four years out
|
||
|
|
||
|
02:00:07.000 --> 02:00:09.000
|
||
|
and eight years out
|
||
|
|
||
|
02:00:09.000 --> 02:00:11.000
|
||
|
has anything to do with what you did
|
||
|
|
||
|
02:00:11.000 --> 02:00:13.000
|
||
|
at time zero
|
||
|
|
||
|
02:00:13.000 --> 02:00:15.000
|
||
|
in a small portion
|
||
|
|
||
|
02:00:15.000 --> 02:00:17.000
|
||
|
of the total population in which you looked
|
||
|
|
||
|
02:00:17.000 --> 02:00:19.000
|
||
|
and yet somehow or another
|
||
|
|
||
|
02:00:19.000 --> 02:00:21.000
|
||
|
these guys have made
|
||
|
|
||
|
02:00:21.000 --> 02:00:23.000
|
||
|
made a theater
|
||
|
|
||
|
02:00:23.000 --> 02:00:25.000
|
||
|
a presentation
|
||
|
|
||
|
02:00:25.000 --> 02:00:27.000
|
||
|
about an illusion of consensus
|
||
|
|
||
|
02:00:27.000 --> 02:00:29.000
|
||
|
that this is a real
|
||
|
|
||
|
02:00:29.000 --> 02:00:31.000
|
||
|
dataset with real
|
||
|
|
||
|
02:00:31.000 --> 02:00:33.000
|
||
|
results that are
|
||
|
|
||
|
02:00:33.000 --> 02:00:35.000
|
||
|
interpretable as
|
||
|
|
||
|
02:00:35.000 --> 02:00:37.000
|
||
|
indicating
|
||
|
|
||
|
02:00:37.000 --> 02:00:39.000
|
||
|
that HPV vaccination
|
||
|
|
||
|
02:00:39.000 --> 02:00:41.000
|
||
|
in teenagers
|
||
|
|
||
|
02:00:41.000 --> 02:00:43.000
|
||
|
depending on whether you do it in girls
|
||
|
|
||
|
02:00:43.000 --> 02:00:45.000
|
||
|
or in boys has differential effect
|
||
|
|
||
|
02:00:45.000 --> 02:00:47.000
|
||
|
on the ecology
|
||
|
|
||
|
02:00:47.000 --> 02:00:49.000
|
||
|
of human papilloma virus
|
||
|
|
||
|
02:00:49.000 --> 02:00:51.000
|
||
|
distribution among teenagers
|
||
|
|
||
|
02:00:55.000 --> 02:00:57.000
|
||
|
and it's really just a synthetic
|
||
|
|
||
|
02:00:57.000 --> 02:00:59.000
|
||
|
generated dataset
|
||
|
|
||
|
02:00:59.000 --> 02:01:01.000
|
||
|
based on an incomplete
|
||
|
|
||
|
02:01:05.000 --> 02:01:07.000
|
||
|
observation set
|
||
|
|
||
|
02:01:09.000 --> 02:01:11.000
|
||
|
and now what you need to understand is
|
||
|
|
||
|
02:01:11.000 --> 02:01:13.000
|
||
|
that almost all
|
||
|
|
||
|
02:01:13.000 --> 02:01:15.000
|
||
|
biology about
|
||
|
|
||
|
02:01:15.000 --> 02:01:17.000
|
||
|
vaccine-targetable disease
|
||
|
|
||
|
02:01:17.000 --> 02:01:19.000
|
||
|
about all biology
|
||
|
|
||
|
02:01:19.000 --> 02:01:21.000
|
||
|
based on
|
||
|
|
||
|
02:01:21.000 --> 02:01:23.000
|
||
|
augmenting the immune system
|
||
|
|
||
|
02:01:23.000 --> 02:01:25.000
|
||
|
is done with a similar
|
||
|
|
||
|
02:01:25.000 --> 02:01:27.000
|
||
|
level of obfuscation
|
||
|
|
||
|
02:01:27.000 --> 02:01:29.000
|
||
|
exaggeration
|
||
|
|
||
|
02:01:29.000 --> 02:01:31.000
|
||
|
oversimplification
|
||
|
|
||
|
02:01:31.000 --> 02:01:33.000
|
||
|
and over complication
|
||
|
|
||
|
02:01:33.000 --> 02:01:35.000
|
||
|
it's these combinations of
|
||
|
|
||
|
02:01:35.000 --> 02:01:37.000
|
||
|
enchantments that allow them to make
|
||
|
|
||
|
02:01:37.000 --> 02:01:39.000
|
||
|
statements which move
|
||
|
|
||
|
02:01:39.000 --> 02:01:41.000
|
||
|
biosecurity states which can
|
||
|
|
||
|
02:01:41.000 --> 02:01:43.000
|
||
|
move secret meetings which can
|
||
|
|
||
|
02:01:43.000 --> 02:01:45.000
|
||
|
move trillions of dollars
|
||
|
|
||
|
02:01:45.000 --> 02:01:47.000
|
||
|
behind the scenes
|
||
|
|
||
|
02:01:47.000 --> 02:01:49.000
|
||
|
based on oversimplification
|
||
|
|
||
|
02:01:49.000 --> 02:01:51.000
|
||
|
over exaggeration
|
||
|
|
||
|
02:01:51.000 --> 02:01:53.000
|
||
|
over complication
|
||
|
|
||
|
02:01:53.000 --> 02:01:57.000
|
||
|
and a semantic war
|
||
|
|
||
|
02:01:57.000 --> 02:01:59.000
|
||
|
where we take known
|
||
|
|
||
|
02:01:59.000 --> 02:02:01.000
|
||
|
and understood biological
|
||
|
|
||
|
02:02:01.000 --> 02:02:03.000
|
||
|
phenomenon that exists on the species level
|
||
|
|
||
|
02:02:03.000 --> 02:02:05.000
|
||
|
and try to apply it to an
|
||
|
|
||
|
02:02:05.000 --> 02:02:07.000
|
||
|
RNA phenomenon
|
||
|
|
||
|
02:02:07.000 --> 02:02:09.000
|
||
|
or even a DNA
|
||
|
|
||
|
02:02:09.000 --> 02:02:11.000
|
||
|
phenomenon
|
||
|
|
||
|
02:02:11.000 --> 02:02:13.000
|
||
|
which is wholly
|
||
|
|
||
|
02:02:13.000 --> 02:02:15.000
|
||
|
and equivalent to species
|
||
|
|
||
|
02:02:15.000 --> 02:02:17.000
|
||
|
level and ecosystem
|
||
|
|
||
|
02:02:17.000 --> 02:02:19.000
|
||
|
level phenomenon as we understand them
|
||
|
|
||
|
02:02:19.000 --> 02:02:21.000
|
||
|
in macrobiology
|
||
|
|
||
|
02:02:21.000 --> 02:02:23.000
|
||
|
and while
|
||
|
|
||
|
02:02:23.000 --> 02:02:25.000
|
||
|
the old man in the upper right is really
|
||
|
|
||
|
02:02:25.000 --> 02:02:27.000
|
||
|
feeling the grinding
|
||
|
|
||
|
02:02:27.000 --> 02:02:29.000
|
||
|
of the gears here as they have
|
||
|
|
||
|
02:02:29.000 --> 02:02:31.000
|
||
|
this very inaccurate, very
|
||
|
|
||
|
02:02:31.000 --> 02:02:33.000
|
||
|
imprecise discussion
|
||
|
|
||
|
02:02:33.000 --> 02:02:35.000
|
||
|
about a very
|
||
|
|
||
|
02:02:35.000 --> 02:02:37.000
|
||
|
pretty crappy paper
|
||
|
|
||
|
02:02:37.000 --> 02:02:39.000
|
||
|
trying to laud it
|
||
|
|
||
|
02:02:39.000 --> 02:02:41.000
|
||
|
as bonafide
|
||
|
|
||
|
02:02:41.000 --> 02:02:43.000
|
||
|
example of
|
||
|
|
||
|
02:02:43.000 --> 02:02:45.000
|
||
|
vaccine effectiveness
|
||
|
|
||
|
02:02:47.000 --> 02:02:49.000
|
||
|
it's brutal
|
||
|
|
||
|
02:02:49.000 --> 02:02:51.000
|
||
|
but this is how the war is waged
|
||
|
|
||
|
02:02:51.000 --> 02:02:53.000
|
||
|
this is how it's done
|
||
|
|
||
|
02:02:53.000 --> 02:02:55.000
|
||
|
this is the actual battlefield
|
||
|
|
||
|
02:02:55.000 --> 02:02:57.000
|
||
|
right here
|
||
|
|
||
|
02:02:57.000 --> 02:02:59.000
|
||
|
and this is why Gigoen biological
|
||
|
|
||
|
02:02:59.000 --> 02:03:01.000
|
||
|
is going to have years of work to do
|
||
|
|
||
|
02:03:01.000 --> 02:03:03.000
|
||
|
this breaking down
|
||
|
|
||
|
02:03:03.000 --> 02:03:05.000
|
||
|
needs to happen every day
|
||
|
|
||
|
02:03:05.000 --> 02:03:07.000
|
||
|
all the time
|
||
|
|
||
|
02:03:07.000 --> 02:03:09.000
|
||
|
constantly
|
||
|
|
||
|
02:03:09.000 --> 02:03:11.000
|
||
|
until people start to catch on
|
||
|
|
||
|
02:03:11.000 --> 02:03:13.000
|
||
|
and do it with me
|
||
|
|
||
|
02:03:13.000 --> 02:03:15.000
|
||
|
until people start to catch on
|
||
|
|
||
|
02:03:15.000 --> 02:03:17.000
|
||
|
and do it as well as me
|
||
|
|
||
|
02:03:17.000 --> 02:03:19.000
|
||
|
until this starts to catch on
|
||
|
|
||
|
02:03:19.000 --> 02:03:21.000
|
||
|
as a thing that people do
|
||
|
|
||
|
02:03:21.000 --> 02:03:23.000
|
||
|
until these people stop
|
||
|
|
||
|
02:03:23.000 --> 02:03:25.000
|
||
|
doing what they're doing
|
||
|
|
||
|
02:03:25.000 --> 02:03:27.000
|
||
|
because this is part of
|
||
|
|
||
|
02:03:27.000 --> 02:03:29.000
|
||
|
the apparatus that
|
||
|
|
||
|
02:03:29.000 --> 02:03:31.000
|
||
|
misleads doctors
|
||
|
|
||
|
02:03:31.000 --> 02:03:33.000
|
||
|
that underpins the assumptions
|
||
|
|
||
|
02:03:33.000 --> 02:03:35.000
|
||
|
that the conclusions
|
||
|
|
||
|
02:03:35.000 --> 02:03:37.000
|
||
|
that doctors assume are certain
|
||
|
|
||
|
02:03:37.000 --> 02:03:39.000
|
||
|
are caused
|
||
|
|
||
|
02:03:39.000 --> 02:03:41.000
|
||
|
by these kinds of discussions
|
||
|
|
||
|
02:03:41.000 --> 02:03:43.000
|
||
|
these people whose
|
||
|
|
||
|
02:03:43.000 --> 02:03:45.000
|
||
|
academic responsibility has been
|
||
|
|
||
|
02:03:45.000 --> 02:03:47.000
|
||
|
abdicated
|
||
|
|
||
|
02:03:47.000 --> 02:03:49.000
|
||
|
by their own incompetence
|
||
|
|
||
|
02:03:49.000 --> 02:03:51.000
|
||
|
by their own lack of curiosity
|
||
|
|
||
|
02:03:53.000 --> 02:03:55.000
|
||
|
every one of these gentlemen
|
||
|
|
||
|
02:03:55.000 --> 02:03:57.000
|
||
|
should and ladies should be upset
|
||
|
|
||
|
02:03:57.000 --> 02:03:59.000
|
||
|
and ashamed of themselves
|
||
|
|
||
|
02:03:59.000 --> 02:04:01.000
|
||
|
for having been
|
||
|
|
||
|
02:04:01.000 --> 02:04:03.000
|
||
|
in their chair for that long
|
||
|
|
||
|
02:04:03.000 --> 02:04:05.000
|
||
|
and having learned so little
|
||
|
|
||
|
02:04:05.000 --> 02:04:07.000
|
||
|
on their own.
|
||
|
|
||
|
02:04:07.000 --> 02:04:09.000
|
||
|
Let me say that again
|
||
|
|
||
|
02:04:09.000 --> 02:04:11.000
|
||
|
every one of these people
|
||
|
|
||
|
02:04:11.000 --> 02:04:13.000
|
||
|
in these chairs and almost
|
||
|
|
||
|
02:04:13.000 --> 02:04:15.000
|
||
|
all the academic biologists
|
||
|
|
||
|
02:04:15.000 --> 02:04:17.000
|
||
|
currently sitting
|
||
|
|
||
|
02:04:17.000 --> 02:04:19.000
|
||
|
in a tenure-track position
|
||
|
|
||
|
02:04:19.000 --> 02:04:21.000
|
||
|
should be ashamed of themselves
|
||
|
|
||
|
02:04:21.000 --> 02:04:23.000
|
||
|
because they have abdicated
|
||
|
|
||
|
02:04:23.000 --> 02:04:25.000
|
||
|
their responsibilities
|
||
|
|
||
|
02:04:25.000 --> 02:04:27.000
|
||
|
as professional biologists
|
||
|
|
||
|
02:04:27.000 --> 02:04:29.000
|
||
|
to understand the biology
|
||
|
|
||
|
02:04:29.000 --> 02:04:31.000
|
||
|
of vaccination and to understand
|
||
|
|
||
|
02:04:31.000 --> 02:04:33.000
|
||
|
that it has been
|
||
|
|
||
|
02:04:33.000 --> 02:04:35.000
|
||
|
oversimplified
|
||
|
|
||
|
02:04:35.000 --> 02:04:37.000
|
||
|
it has been grossly exaggerated
|
||
|
|
||
|
02:04:37.000 --> 02:04:39.000
|
||
|
ineffectiveness and value
|
||
|
|
||
|
02:04:39.000 --> 02:04:41.000
|
||
|
and we have contorted it
|
||
|
|
||
|
02:04:41.000 --> 02:04:43.000
|
||
|
into a
|
||
|
|
||
|
02:04:43.000 --> 02:04:45.000
|
||
|
a gigantic criminal
|
||
|
|
||
|
02:04:45.000 --> 02:04:47.000
|
||
|
enterprise
|
||
|
|
||
|
02:04:47.000 --> 02:04:49.000
|
||
|
and it is absolutely
|
||
|
|
||
|
02:04:49.000 --> 02:04:51.000
|
||
|
criminally negligent to
|
||
|
|
||
|
02:04:51.000 --> 02:04:53.000
|
||
|
intramuscular inject
|
||
|
|
||
|
02:04:53.000 --> 02:04:55.000
|
||
|
intramuscularly inject
|
||
|
|
||
|
02:04:55.000 --> 02:04:57.000
|
||
|
any combination of substances
|
||
|
|
||
|
02:04:57.000 --> 02:04:59.000
|
||
|
in the vaccine system
|
||
|
|
||
|
02:04:59.000 --> 02:05:01.000
|
||
|
it is definitely criminally negligent
|
||
|
|
||
|
02:05:01.000 --> 02:05:03.000
|
||
|
and it is only because
|
||
|
|
||
|
02:05:03.000 --> 02:05:05.000
|
||
|
doctors don't understand the biology
|
||
|
|
||
|
02:05:05.000 --> 02:05:07.000
|
||
|
it is only because
|
||
|
|
||
|
02:05:07.000 --> 02:05:09.000
|
||
|
the NIAID and the vaccine center
|
||
|
|
||
|
02:05:09.000 --> 02:05:11.000
|
||
|
and all these people
|
||
|
|
||
|
02:05:11.000 --> 02:05:13.000
|
||
|
have obfuscated the truth
|
||
|
|
||
|
02:05:13.000 --> 02:05:15.000
|
||
|
of the biology of the immune system
|
||
|
|
||
|
02:05:15.000 --> 02:05:17.000
|
||
|
that they don't understand
|
||
|
|
||
|
02:05:17.000 --> 02:05:19.000
|
||
|
you can't
|
||
|
|
||
|
02:05:19.000 --> 02:05:21.000
|
||
|
you have to follow these
|
||
|
|
||
|
02:05:21.000 --> 02:05:23.000
|
||
|
and suddenly in vaccinated people
|
||
|
|
||
|
02:05:23.000 --> 02:05:25.000
|
||
|
we start to see cancer as HPV
|
||
|
|
||
|
02:05:25.000 --> 02:05:27.000
|
||
|
that is causing them
|
||
|
|
||
|
02:05:27.000 --> 02:05:29.000
|
||
|
Absolutely
|
||
|
|
||
|
02:05:29.000 --> 02:05:31.000
|
||
|
I've been trying to figure out
|
||
|
|
||
|
02:05:31.000 --> 02:05:33.000
|
||
|
the answer to Dixon's question
|
||
|
|
||
|
02:05:33.000 --> 02:05:35.000
|
||
|
which I think is interesting
|
||
|
|
||
|
02:05:35.000 --> 02:05:37.000
|
||
|
which is what is the geographic
|
||
|
|
||
|
02:05:37.000 --> 02:05:39.000
|
||
|
distribution of the different types
|
||
|
|
||
|
02:05:39.000 --> 02:05:41.000
|
||
|
around the world
|
||
|
|
||
|
02:05:41.000 --> 02:05:43.000
|
||
|
and while I found various titles
|
||
|
|
||
|
02:05:43.000 --> 02:05:45.000
|
||
|
and hits that seemed like they were
|
||
|
|
||
|
02:05:45.000 --> 02:05:47.000
|
||
|
going to be informative
|
||
|
|
||
|
02:05:47.000 --> 02:05:49.000
|
||
|
I didn't find anything that really addresses
|
||
|
|
||
|
02:05:49.000 --> 02:05:51.000
|
||
|
that question
|
||
|
|
||
|
02:05:51.000 --> 02:05:53.000
|
||
|
how many types are all together
|
||
|
|
||
|
02:05:53.000 --> 02:05:55.000
|
||
|
and I was going to say a hundred
|
||
|
|
||
|
02:05:55.000 --> 02:05:57.000
|
||
|
and yet only these two
|
||
|
|
||
|
02:05:57.000 --> 02:05:59.000
|
||
|
it's more than 200 so again
|
||
|
|
||
|
02:05:59.000 --> 02:06:01.000
|
||
|
the virology professor of the world
|
||
|
|
||
|
02:06:01.000 --> 02:06:03.000
|
||
|
has no idea how many serotypes
|
||
|
|
||
|
02:06:03.000 --> 02:06:05.000
|
||
|
there are and more importantly
|
||
|
|
||
|
02:06:05.000 --> 02:06:07.000
|
||
|
he's going to try to avoid saying
|
||
|
|
||
|
02:06:07.000 --> 02:06:09.000
|
||
|
that all the other biological
|
||
|
|
||
|
02:06:09.000 --> 02:06:11.000
|
||
|
principles apply to human
|
||
|
|
||
|
02:06:11.000 --> 02:06:13.000
|
||
|
papilloma virus but the guy in the upper
|
||
|
|
||
|
02:06:13.000 --> 02:06:15.000
|
||
|
right is not going to let him get away
|
||
|
|
||
|
02:06:15.000 --> 02:06:17.000
|
||
|
around the world are responsible
|
||
|
|
||
|
02:06:17.000 --> 02:06:19.000
|
||
|
for the surgical cancer
|
||
|
|
||
|
02:06:19.000 --> 02:06:21.000
|
||
|
and why is this guy down here
|
||
|
|
||
|
02:06:21.000 --> 02:06:23.000
|
||
|
Alan Dove at the bottom saying nine
|
||
|
|
||
|
02:06:23.000 --> 02:06:25.000
|
||
|
when we started out the discussion
|
||
|
|
||
|
02:06:25.000 --> 02:06:27.000
|
||
|
he was sure it was just two
|
||
|
|
||
|
02:06:27.000 --> 02:06:29.000
|
||
|
and then surely behind me here
|
||
|
|
||
|
02:06:29.000 --> 02:06:31.000
|
||
|
says no it's also 36 and 38
|
||
|
|
||
|
02:06:31.000 --> 02:06:33.000
|
||
|
oh yeah that's right
|
||
|
|
||
|
02:06:33.000 --> 02:06:35.000
|
||
|
and then later on five to ten
|
||
|
|
||
|
02:06:35.000 --> 02:06:37.000
|
||
|
minutes later it's oh yeah there's nine
|
||
|
|
||
|
02:06:37.000 --> 02:06:39.000
|
||
|
of them now
|
||
|
|
||
|
02:06:39.000 --> 02:06:41.000
|
||
|
and so now he says like yeah
|
||
|
|
||
|
02:06:41.000 --> 02:06:43.000
|
||
|
it's nine as if he knew
|
||
|
|
||
|
02:06:43.000 --> 02:06:45.000
|
||
|
or he didn't learn it like 20 minutes
|
||
|
|
||
|
02:06:45.000 --> 02:06:47.000
|
||
|
ago
|
||
|
|
||
|
02:06:47.000 --> 02:06:49.000
|
||
|
this is the kind of arrogance
|
||
|
|
||
|
02:06:49.000 --> 02:06:53.000
|
||
|
that we need to fight against
|
||
|
|
||
|
02:06:53.000 --> 02:06:57.000
|
||
|
that's not a humble man
|
||
|
|
||
|
02:06:57.000 --> 02:06:59.000
|
||
|
that's a guy as I said before
|
||
|
|
||
|
02:06:59.000 --> 02:07:01.000
|
||
|
who's just waiting to repeat what he just
|
||
|
|
||
|
02:07:01.000 --> 02:07:03.000
|
||
|
heard so that he can sound smart again
|
||
|
|
||
|
02:07:03.000 --> 02:07:05.000
|
||
|
and he loves doing it
|
||
|
|
||
|
02:07:05.000 --> 02:07:07.000
|
||
|
he loves the one yard rushing
|
||
|
|
||
|
02:07:07.000 --> 02:07:09.000
|
||
|
touchdown
|
||
|
|
||
|
02:07:09.000 --> 02:07:11.000
|
||
|
with an offensive line
|
||
|
|
||
|
02:07:11.000 --> 02:07:13.000
|
||
|
of high schoolers against
|
||
|
|
||
|
02:07:13.000 --> 02:07:15.000
|
||
|
Pee Wee football
|
||
|
|
||
|
02:07:15.000 --> 02:07:17.000
|
||
|
he loves to be the running back
|
||
|
|
||
|
02:07:17.000 --> 02:07:18.000
|
||
|
in that scenario
|
||
|
|
||
|
02:07:18.000 --> 02:07:20.000
|
||
|
give me the ball coach
|
||
|
|
||
|
02:07:20.000 --> 02:07:22.000
|
||
|
I can happy to repeat the line
|
||
|
|
||
|
02:07:26.000 --> 02:07:28.000
|
||
|
but he's not willing to put his
|
||
|
|
||
|
02:07:28.000 --> 02:07:30.000
|
||
|
his academic you know
|
||
|
|
||
|
02:07:30.000 --> 02:07:32.000
|
||
|
and intellectual mind out on a cliff
|
||
|
|
||
|
02:07:32.000 --> 02:07:34.000
|
||
|
and think for himself
|
||
|
|
||
|
02:07:35.000 --> 02:07:37.000
|
||
|
but every time he hears a safe spot
|
||
|
|
||
|
02:07:37.000 --> 02:07:39.000
|
||
|
or a safe thing to say is correct
|
||
|
|
||
|
02:07:39.000 --> 02:07:41.000
|
||
|
or a safe thing that he thinks is certain
|
||
|
|
||
|
02:07:41.000 --> 02:07:43.000
|
||
|
he'll repeat it immediately
|
||
|
|
||
|
02:07:43.000 --> 02:07:45.000
|
||
|
and here he is saying
|
||
|
|
||
|
02:07:45.000 --> 02:07:47.000
|
||
|
yeah it's nine it's nine of them
|
||
|
|
||
|
02:07:47.000 --> 02:07:49.000
|
||
|
even though I didn't even know there was
|
||
|
|
||
|
02:07:49.000 --> 02:07:51.000
|
||
|
Gardasil nine until ten minutes ago
|
||
|
|
||
|
02:07:51.000 --> 02:07:53.000
|
||
|
yeah there's nine of them
|
||
|
|
||
|
02:07:53.000 --> 02:07:54.000
|
||
|
don't you know man?
|
||
|
|
||
|
02:07:54.000 --> 02:07:56.000
|
||
|
how many types are there altogether?
|
||
|
|
||
|
02:07:56.000 --> 02:07:57.000
|
||
|
that's another question
|
||
|
|
||
|
02:07:57.000 --> 02:07:59.000
|
||
|
oh there's at least I was going to say a hundred
|
||
|
|
||
|
02:07:59.000 --> 02:08:01.000
|
||
|
oh maybe yeah
|
||
|
|
||
|
02:08:01.000 --> 02:08:03.000
|
||
|
and yet only these two around the world
|
||
|
|
||
|
02:08:03.000 --> 02:08:05.000
|
||
|
are responsible for these
|
||
|
|
||
|
02:08:05.000 --> 02:08:07.000
|
||
|
well the nine
|
||
|
|
||
|
02:08:07.000 --> 02:08:09.000
|
||
|
I'm at the right
|
||
|
|
||
|
02:08:09.000 --> 02:08:11.000
|
||
|
and potentially more than that
|
||
|
|
||
|
02:08:11.000 --> 02:08:13.000
|
||
|
I mean there's the high on cryogenic and the low on cryogenic
|
||
|
|
||
|
02:08:13.000 --> 02:08:15.000
|
||
|
and even high risk and low risk
|
||
|
|
||
|
02:08:15.000 --> 02:08:17.000
|
||
|
and ontogenicity
|
||
|
|
||
|
02:08:17.000 --> 02:08:19.000
|
||
|
are based on almost no data
|
||
|
|
||
|
02:08:19.000 --> 02:08:21.000
|
||
|
if not zero
|
||
|
|
||
|
02:08:23.000 --> 02:08:25.000
|
||
|
it's really the truth
|
||
|
|
||
|
02:08:25.000 --> 02:08:27.000
|
||
|
I challenge anybody go find it
|
||
|
|
||
|
02:08:27.000 --> 02:08:29.000
|
||
|
if you're a doctor, if you're a skeptic
|
||
|
|
||
|
02:08:29.000 --> 02:08:31.000
|
||
|
go find papers that show
|
||
|
|
||
|
02:08:31.000 --> 02:08:33.000
|
||
|
real data about HPV
|
||
|
|
||
|
02:08:33.000 --> 02:08:35.000
|
||
|
and cancer
|
||
|
|
||
|
02:08:35.000 --> 02:08:37.000
|
||
|
and which
|
||
|
|
||
|
02:08:37.000 --> 02:08:39.000
|
||
|
serotypes cause it
|
||
|
|
||
|
02:08:39.000 --> 02:08:41.000
|
||
|
which of the hundreds of
|
||
|
|
||
|
02:08:41.000 --> 02:08:43.000
|
||
|
serotypes known cause cancer
|
||
|
|
||
|
02:08:43.000 --> 02:08:45.000
|
||
|
and which don't
|
||
|
|
||
|
02:08:45.000 --> 02:08:47.000
|
||
|
which just cause warts
|
||
|
|
||
|
02:08:47.000 --> 02:08:49.000
|
||
|
which ones
|
||
|
|
||
|
02:08:51.000 --> 02:08:53.000
|
||
|
they're basically justifying
|
||
|
|
||
|
02:08:53.000 --> 02:08:55.000
|
||
|
a Merck product
|
||
|
|
||
|
02:08:55.000 --> 02:08:57.000
|
||
|
what else are they doing here
|
||
|
|
||
|
02:08:57.000 --> 02:08:59.000
|
||
|
but defending a Merck product
|
||
|
|
||
|
02:08:59.000 --> 02:09:01.000
|
||
|
with with with Glasgow Smith
|
||
|
|
||
|
02:09:01.000 --> 02:09:03.000
|
||
|
Klein intellectual property
|
||
|
|
||
|
02:09:03.000 --> 02:09:05.000
|
||
|
what else are they doing?
|
||
|
|
||
|
02:09:05.000 --> 02:09:07.000
|
||
|
they're not arguing for the biology of it
|
||
|
|
||
|
02:09:07.000 --> 02:09:09.000
|
||
|
they're not even arguing about the biology of it
|
||
|
|
||
|
02:09:09.000 --> 02:09:11.000
|
||
|
the whole premise is that it
|
||
|
|
||
|
02:09:11.000 --> 02:09:13.000
|
||
|
prevents cancer
|
||
|
|
||
|
02:09:13.000 --> 02:09:15.000
|
||
|
this is a story about
|
||
|
|
||
|
02:09:15.000 --> 02:09:17.000
|
||
|
seroprevalence to zero types
|
||
|
|
||
|
02:09:17.000 --> 02:09:19.000
|
||
|
extended through math
|
||
|
|
||
|
02:09:21.000 --> 02:09:23.000
|
||
|
that's what this is about
|
||
|
|
||
|
02:09:23.000 --> 02:09:25.000
|
||
|
it's not about anything to do with the actual biology
|
||
|
|
||
|
02:09:25.000 --> 02:09:27.000
|
||
|
that this vaccine purports to
|
||
|
|
||
|
02:09:27.000 --> 02:09:29.000
|
||
|
encroach on
|
||
|
|
||
|
02:09:29.000 --> 02:09:31.000
|
||
|
so it's unclear
|
||
|
|
||
|
02:09:31.000 --> 02:09:33.000
|
||
|
how far exactly we've gotten down the risk tree
|
||
|
|
||
|
02:09:33.000 --> 02:09:35.000
|
||
|
but with the nine valent
|
||
|
|
||
|
02:09:35.000 --> 02:09:37.000
|
||
|
it's pretty clear like
|
||
|
|
||
|
02:09:37.000 --> 02:09:39.000
|
||
|
maybe everything maybe there's going to have to be a 10 valent
|
||
|
|
||
|
02:09:39.000 --> 02:09:41.000
|
||
|
later when we discover that there are some
|
||
|
|
||
|
02:09:41.000 --> 02:09:43.000
|
||
|
rare situations where one of these others can be cancerous
|
||
|
|
||
|
02:09:43.000 --> 02:09:45.000
|
||
|
you know so that's possible
|
||
|
|
||
|
02:09:45.000 --> 02:09:47.000
|
||
|
but this guy literally learned
|
||
|
|
||
|
02:09:47.000 --> 02:09:49.000
|
||
|
this biology and the course of
|
||
|
|
||
|
02:09:49.000 --> 02:09:51.000
|
||
|
this discussion he's talking like he
|
||
|
|
||
|
02:09:51.000 --> 02:09:53.000
|
||
|
he's the the jeopardy champion
|
||
|
|
||
|
02:09:53.000 --> 02:09:55.000
|
||
|
of HPV biology
|
||
|
|
||
|
02:09:55.000 --> 02:09:57.000
|
||
|
it's really sad
|
||
|
|
||
|
02:09:59.000 --> 02:10:01.000
|
||
|
I mean if I was on this
|
||
|
|
||
|
02:10:01.000 --> 02:10:03.000
|
||
|
Twiv thing I would be like hey Alan why don't you
|
||
|
|
||
|
02:10:03.000 --> 02:10:05.000
|
||
|
chill out a little bit you didn't even know about
|
||
|
|
||
|
02:10:05.000 --> 02:10:07.000
|
||
|
these are the
|
||
|
|
||
|
02:10:07.000 --> 02:10:09.000
|
||
|
these are the
|
||
|
|
||
|
02:10:09.000 --> 02:10:11.000
|
||
|
these are the big concerns
|
||
|
|
||
|
02:10:11.000 --> 02:10:13.000
|
||
|
okay so there are over 100 different types of
|
||
|
|
||
|
02:10:13.000 --> 02:10:15.000
|
||
|
HPV not all of them cause health problems
|
||
|
|
||
|
02:10:15.000 --> 02:10:17.000
|
||
|
some kinds may cause problems like genital warts
|
||
|
|
||
|
02:10:17.000 --> 02:10:19.000
|
||
|
some kinds can also cause cancer of the cervix
|
||
|
|
||
|
02:10:19.000 --> 02:10:21.000
|
||
|
vagina vulva or anus
|
||
|
|
||
|
02:10:21.000 --> 02:10:23.000
|
||
|
most of these problems are caused by type 611 16 or 18
|
||
|
|
||
|
02:10:23.000 --> 02:10:25.000
|
||
|
November 1st FDA
|
||
|
|
||
|
02:10:25.000 --> 02:10:27.000
|
||
|
oh so
|
||
|
|
||
|
02:10:27.000 --> 02:10:29.000
|
||
|
she found a document from the FDA
|
||
|
|
||
|
02:10:29.000 --> 02:10:31.000
|
||
|
which clears up
|
||
|
|
||
|
02:10:31.000 --> 02:10:33.000
|
||
|
this whole thing about the 200 plus
|
||
|
|
||
|
02:10:33.000 --> 02:10:36.000
|
||
|
zero types and whether they cause cancer or not
|
||
|
|
||
|
02:10:36.000 --> 02:10:37.000
|
||
|
gee thanks
|
||
|
|
||
|
02:10:39.000 --> 02:10:41.000
|
||
|
over 100 okay
|
||
|
|
||
|
02:10:41.000 --> 02:10:43.000
|
||
|
and they're classified at the high risk low risk
|
||
|
|
||
|
02:10:43.000 --> 02:10:45.000
|
||
|
and no risk no no observe risk
|
||
|
|
||
|
02:10:45.000 --> 02:10:47.000
|
||
|
no observe risk right
|
||
|
|
||
|
02:10:47.000 --> 02:10:49.000
|
||
|
one two three four five six
|
||
|
|
||
|
02:10:49.000 --> 02:10:51.000
|
||
|
seven eight nine ten eleven twelve thirteen high risk
|
||
|
|
||
|
02:10:51.000 --> 02:10:53.000
|
||
|
so not all the high risk are in the vaccine because
|
||
|
|
||
|
02:10:53.000 --> 02:10:55.000
|
||
|
I think that just there's not enough infections
|
||
|
|
||
|
02:10:55.000 --> 02:10:57.000
|
||
|
right but maybe that could change right
|
||
|
|
||
|
02:10:57.000 --> 02:10:59.000
|
||
|
yeah and it's like well like or a
|
||
|
|
||
|
02:10:59.000 --> 02:11:01.000
|
||
|
for angel cancer people now talk about HPV
|
||
|
|
||
|
02:11:01.000 --> 02:11:03.000
|
||
|
causing it but
|
||
|
|
||
|
02:11:03.000 --> 02:11:05.000
|
||
|
if you go back 30 or 40 years
|
||
|
|
||
|
02:11:05.000 --> 02:11:07.000
|
||
|
HPV was not really a big topic of conversation for
|
||
|
|
||
|
02:11:07.000 --> 02:11:09.000
|
||
|
oral for angel cancer because the overwhelming majority of it
|
||
|
|
||
|
02:11:09.000 --> 02:11:11.000
|
||
|
was caused by smoking right and when smoking rates
|
||
|
|
||
|
02:11:11.000 --> 02:11:13.000
|
||
|
came down thanks to you know finally
|
||
|
|
||
|
02:11:13.000 --> 02:11:15.000
|
||
|
calling out the tobacco companies to account
|
||
|
|
||
|
02:11:15.000 --> 02:11:17.000
|
||
|
the you know that
|
||
|
|
||
|
02:11:17.000 --> 02:11:19.000
|
||
|
then revealed oh yeah by the way there are
|
||
|
|
||
|
02:11:19.000 --> 02:11:21.000
|
||
|
a lot of cases out there that aren't caused
|
||
|
|
||
|
02:11:21.000 --> 02:11:23.000
|
||
|
right so you didn't see those because there
|
||
|
|
||
|
02:11:23.000 --> 02:11:25.000
|
||
|
was so much else going on and it's possible with
|
||
|
|
||
|
02:11:25.000 --> 02:11:27.000
|
||
|
with these cancer causing HPV's
|
||
|
|
||
|
02:11:27.000 --> 02:11:29.000
|
||
|
now that you get the vaccine when that's gotten
|
||
|
|
||
|
02:11:29.000 --> 02:11:31.000
|
||
|
wide enough uptake we'll get to a point where we'll say
|
||
|
|
||
|
02:11:31.000 --> 02:11:33.000
|
||
|
okay we got most of it and now
|
||
|
|
||
|
02:11:33.000 --> 02:11:35.000
|
||
|
there are these remaining ones and as I say that might
|
||
|
|
||
|
02:11:35.000 --> 02:11:37.000
|
||
|
be time to add more to the
|
||
|
|
||
|
02:11:37.000 --> 02:11:39.000
|
||
|
vaccine but this is certainly proven
|
||
|
|
||
|
02:11:39.000 --> 02:11:41.000
|
||
|
a very very successful strategy
|
||
|
|
||
|
02:11:41.000 --> 02:11:43.000
|
||
|
a very very successful strategy
|
||
|
|
||
|
02:11:43.000 --> 02:11:45.000
|
||
|
it's proven a very very successful strategy
|
||
|
|
||
|
02:11:45.000 --> 02:11:47.000
|
||
|
I'm going to give you another example
|
||
|
|
||
|
02:11:47.000 --> 02:11:49.000
|
||
|
of how numbers can
|
||
|
|
||
|
02:11:49.000 --> 02:11:51.000
|
||
|
be distorted in a very
|
||
|
|
||
|
02:11:51.000 --> 02:11:53.000
|
||
|
disingenuous way that is
|
||
|
|
||
|
02:11:53.000 --> 02:11:55.000
|
||
|
not unlike what is being done here
|
||
|
|
||
|
02:11:55.000 --> 02:11:59.000
|
||
|
if you were a politician in Chicago you might make
|
||
|
|
||
|
02:11:59.000 --> 02:12:03.000
|
||
|
the statement that gun deaths in Chicago are on a decline
|
||
|
|
||
|
02:12:03.000 --> 02:12:07.000
|
||
|
and over the last 10 years they've been on a great decline
|
||
|
|
||
|
02:12:07.000 --> 02:12:11.000
|
||
|
and so a lot of the policing process and the policing
|
||
|
|
||
|
02:12:11.000 --> 02:12:13.000
|
||
|
in Chicago has been successful
|
||
|
|
||
|
02:12:13.000 --> 02:12:15.000
|
||
|
and that would be ridiculous statement
|
||
|
|
||
|
02:12:15.000 --> 02:12:17.000
|
||
|
for one reason and one reason only
|
||
|
|
||
|
02:12:17.000 --> 02:12:19.000
|
||
|
the reason why gun deaths have gone down in Chicago
|
||
|
|
||
|
02:12:19.000 --> 02:12:23.000
|
||
|
is because the ERs have become better at saving people
|
||
|
|
||
|
02:12:23.000 --> 02:12:27.000
|
||
|
from dying from gunshot wounds
|
||
|
|
||
|
02:12:27.000 --> 02:12:29.000
|
||
|
they've become better at treating gunshot wounds
|
||
|
|
||
|
02:12:29.000 --> 02:12:31.000
|
||
|
than they were 10 years ago
|
||
|
|
||
|
02:12:31.000 --> 02:12:35.000
|
||
|
and so the number of gunshot deaths has gone down in Chicago
|
||
|
|
||
|
02:12:35.000 --> 02:12:37.000
|
||
|
over the last 20 years
|
||
|
|
||
|
02:12:37.000 --> 02:12:41.000
|
||
|
but the number of gunshot wounds has gone skyrocketing
|
||
|
|
||
|
02:12:43.000 --> 02:12:45.000
|
||
|
and so in a very
|
||
|
|
||
|
02:12:45.000 --> 02:12:47.000
|
||
|
weird limited way
|
||
|
|
||
|
02:12:47.000 --> 02:12:49.000
|
||
|
depending on who you measure
|
||
|
|
||
|
02:12:49.000 --> 02:12:51.000
|
||
|
and how you simulate it
|
||
|
|
||
|
02:12:51.000 --> 02:12:53.000
|
||
|
what math tools you use
|
||
|
|
||
|
02:12:53.000 --> 02:12:55.000
|
||
|
you can create a dataset
|
||
|
|
||
|
02:12:55.000 --> 02:12:57.000
|
||
|
or a synthetic dataset
|
||
|
|
||
|
02:12:57.000 --> 02:12:59.000
|
||
|
which gives the illusion of change
|
||
|
|
||
|
02:12:59.000 --> 02:13:01.000
|
||
|
an illusion of change
|
||
|
|
||
|
02:13:01.000 --> 02:13:03.000
|
||
|
which logically
|
||
|
|
||
|
02:13:03.000 --> 02:13:05.000
|
||
|
when told as a story or a mythology
|
||
|
|
||
|
02:13:05.000 --> 02:13:09.000
|
||
|
seems to correlate well with the expectations
|
||
|
|
||
|
02:13:09.000 --> 02:13:11.000
|
||
|
of your manipulation of the system
|
||
|
|
||
|
02:13:11.000 --> 02:13:13.000
|
||
|
in this case the idea is
|
||
|
|
||
|
02:13:13.000 --> 02:13:15.000
|
||
|
is that the serial prevalence
|
||
|
|
||
|
02:13:15.000 --> 02:13:19.000
|
||
|
of oncogenic strains of HPV
|
||
|
|
||
|
02:13:19.000 --> 02:13:21.000
|
||
|
in our simulation
|
||
|
|
||
|
02:13:21.000 --> 02:13:23.000
|
||
|
based on a small subset of real data
|
||
|
|
||
|
02:13:23.000 --> 02:13:25.000
|
||
|
seems to indicate
|
||
|
|
||
|
02:13:25.000 --> 02:13:27.000
|
||
|
that the serial prevalence
|
||
|
|
||
|
02:13:27.000 --> 02:13:29.000
|
||
|
the serial prevalence
|
||
|
|
||
|
02:13:29.000 --> 02:13:31.000
|
||
|
not the actual presence
|
||
|
|
||
|
02:13:31.000 --> 02:13:33.000
|
||
|
of but the serial prevalence
|
||
|
|
||
|
02:13:33.000 --> 02:13:35.000
|
||
|
to some of these strains
|
||
|
|
||
|
02:13:35.000 --> 02:13:37.000
|
||
|
changes over time in these communities
|
||
|
|
||
|
02:13:37.000 --> 02:13:39.000
|
||
|
when we simulate them
|
||
|
|
||
|
02:13:39.000 --> 02:13:43.000
|
||
|
at the four and eight-year mark
|
||
|
|
||
|
02:13:43.000 --> 02:13:45.000
|
||
|
that's what they should be saying
|
||
|
|
||
|
02:13:45.000 --> 02:13:47.000
|
||
|
that's what it should say in the abstract
|
||
|
|
||
|
02:13:47.000 --> 02:13:49.000
|
||
|
and say in the conclusions
|
||
|
|
||
|
02:13:49.000 --> 02:13:51.000
|
||
|
and in fact
|
||
|
|
||
|
02:13:51.000 --> 02:13:53.000
|
||
|
what is it saying the conclusions
|
||
|
|
||
|
02:13:53.000 --> 02:13:55.000
|
||
|
it says previously
|
||
|
|
||
|
02:13:55.000 --> 02:13:57.000
|
||
|
we modeled from observed HPV
|
||
|
|
||
|
02:13:57.000 --> 02:13:59.000
|
||
|
vaccine trial data
|
||
|
|
||
|
02:13:59.000 --> 02:14:01.000
|
||
|
and showed the need
|
||
|
|
||
|
02:14:01.000 --> 02:14:03.000
|
||
|
to opt for general neutral
|
||
|
|
||
|
02:14:03.000 --> 02:14:05.000
|
||
|
HPV vaccination strategies
|
||
|
|
||
|
02:14:05.000 --> 02:14:07.000
|
||
|
to realistically meet
|
||
|
|
||
|
02:14:07.000 --> 02:14:11.000
|
||
|
the who targeted eradication
|
||
|
|
||
|
02:14:11.000 --> 02:14:13.000
|
||
|
of oncogenic HPV's
|
||
|
|
||
|
02:14:13.000 --> 02:14:15.000
|
||
|
hold on a minute
|
||
|
|
||
|
02:14:15.000 --> 02:14:17.000
|
||
|
are you kidding me?
|
||
|
|
||
|
02:14:21.000 --> 02:14:23.000
|
||
|
this is what I'm reading
|
||
|
|
||
|
02:14:23.000 --> 02:14:25.000
|
||
|
previously we modeled
|
||
|
|
||
|
02:14:25.000 --> 02:14:27.000
|
||
|
from observed HPV
|
||
|
|
||
|
02:14:27.000 --> 02:14:29.000
|
||
|
vaccine trial data and showed
|
||
|
|
||
|
02:14:29.000 --> 02:14:31.000
|
||
|
the need to adopt for general
|
||
|
|
||
|
02:14:31.000 --> 02:14:33.000
|
||
|
neutral HPV vaccination strategies
|
||
|
|
||
|
02:14:33.000 --> 02:14:35.000
|
||
|
to realistically meet
|
||
|
|
||
|
02:14:35.000 --> 02:14:37.000
|
||
|
the who targeted eradication
|
||
|
|
||
|
02:14:37.000 --> 02:14:39.000
|
||
|
of oncogenic HPV's
|
||
|
|
||
|
02:14:39.000 --> 02:14:41.000
|
||
|
that giant sentence says
|
||
|
|
||
|
02:14:41.000 --> 02:14:43.000
|
||
|
that we need to vaccinate
|
||
|
|
||
|
02:14:43.000 --> 02:14:45.000
|
||
|
both teenage girls
|
||
|
|
||
|
02:14:45.000 --> 02:14:47.000
|
||
|
and teenage boys
|
||
|
|
||
|
02:14:47.000 --> 02:14:49.000
|
||
|
in order to realistically
|
||
|
|
||
|
02:14:49.000 --> 02:14:51.000
|
||
|
meet the world health
|
||
|
|
||
|
02:14:51.000 --> 02:14:53.000
|
||
|
organization goal
|
||
|
|
||
|
02:14:53.000 --> 02:14:55.000
|
||
|
of eradicating oncogenic
|
||
|
|
||
|
02:14:55.000 --> 02:14:57.000
|
||
|
HPV's
|
||
|
|
||
|
02:14:57.000 --> 02:14:59.000
|
||
|
now we've just heard the
|
||
|
|
||
|
02:14:59.000 --> 02:15:01.000
|
||
|
Twivcast say that we don't know
|
||
|
|
||
|
02:15:01.000 --> 02:15:03.000
|
||
|
if these other
|
||
|
|
||
|
02:15:03.000 --> 02:15:05.000
|
||
|
possibly 200 or more
|
||
|
|
||
|
02:15:05.000 --> 02:15:07.000
|
||
|
serial prevalence
|
||
|
|
||
|
02:15:07.000 --> 02:15:09.000
|
||
|
types of HPV are not responsible
|
||
|
|
||
|
02:15:09.000 --> 02:15:11.000
|
||
|
for generating cancer
|
||
|
|
||
|
02:15:11.000 --> 02:15:13.000
|
||
|
we just know that a few of them
|
||
|
|
||
|
02:15:13.000 --> 02:15:15.000
|
||
|
have been associated with
|
||
|
|
||
|
02:15:15.000 --> 02:15:17.000
|
||
|
cancer in the studies that we've done
|
||
|
|
||
|
02:15:17.000 --> 02:15:19.000
|
||
|
and yet here we are
|
||
|
|
||
|
02:15:19.000 --> 02:15:21.000
|
||
|
not talking about the biology
|
||
|
|
||
|
02:15:21.000 --> 02:15:23.000
|
||
|
but talking about a world health
|
||
|
|
||
|
02:15:23.000 --> 02:15:25.000
|
||
|
organization goal of eradicating
|
||
|
|
||
|
02:15:25.000 --> 02:15:27.000
|
||
|
oncogenic HPV's
|
||
|
|
||
|
02:15:27.000 --> 02:15:29.000
|
||
|
so to control oncogenic
|
||
|
|
||
|
02:15:29.000 --> 02:15:31.000
|
||
|
HPV's and related cancers
|
||
|
|
||
|
02:15:31.000 --> 02:15:33.000
|
||
|
we need to understand
|
||
|
|
||
|
02:15:33.000 --> 02:15:35.000
|
||
|
the evolutionary dynamic
|
||
|
|
||
|
02:15:35.000 --> 02:15:37.000
|
||
|
of these oncoviruses
|
||
|
|
||
|
02:15:37.000 --> 02:15:39.000
|
||
|
are they oncoviruses?
|
||
|
|
||
|
02:15:39.000 --> 02:15:41.000
|
||
|
we're just calling them
|
||
|
|
||
|
02:15:41.000 --> 02:15:43.000
|
||
|
oncoviruses because
|
||
|
|
||
|
02:15:43.000 --> 02:15:45.000
|
||
|
that makes
|
||
|
|
||
|
02:15:45.000 --> 02:15:47.000
|
||
|
well it makes things simpler
|
||
|
|
||
|
02:15:47.000 --> 02:15:49.000
|
||
|
it makes the assumption
|
||
|
|
||
|
02:15:49.000 --> 02:15:51.000
|
||
|
an enchantment
|
||
|
|
||
|
02:15:51.000 --> 02:15:53.000
|
||
|
we already know this
|
||
|
|
||
|
02:15:53.000 --> 02:15:55.000
|
||
|
don't we?
|
||
|
|
||
|
02:15:55.000 --> 02:15:57.000
|
||
|
no we don't
|
||
|
|
||
|
02:15:57.000 --> 02:15:59.000
|
||
|
but we're going to call them
|
||
|
|
||
|
02:15:59.000 --> 02:16:01.000
|
||
|
oncoviruses so that it seems like
|
||
|
|
||
|
02:16:01.000 --> 02:16:03.000
|
||
|
we do we made a whole term
|
||
|
|
||
|
02:16:03.000 --> 02:16:05.000
|
||
|
for HPV viruses that cause
|
||
|
|
||
|
02:16:05.000 --> 02:16:07.000
|
||
|
cancer it's an oncovirus
|
||
|
|
||
|
02:16:07.000 --> 02:16:09.000
|
||
|
under long-term vaccine
|
||
|
|
||
|
02:16:09.000 --> 02:16:11.000
|
||
|
induced selective pressure
|
||
|
|
||
|
02:16:11.000 --> 02:16:13.000
|
||
|
long-term vaccine induced
|
||
|
|
||
|
02:16:13.000 --> 02:16:15.000
|
||
|
selective pressure
|
||
|
|
||
|
02:16:15.000 --> 02:16:17.000
|
||
|
is a mythology for which
|
||
|
|
||
|
02:16:17.000 --> 02:16:19.000
|
||
|
there is no
|
||
|
|
||
|
02:16:19.000 --> 02:16:21.000
|
||
|
biological evidence
|
||
|
|
||
|
02:16:21.000 --> 02:16:23.000
|
||
|
including in this paper
|
||
|
|
||
|
02:16:23.000 --> 02:16:25.000
|
||
|
because
|
||
|
|
||
|
02:16:25.000 --> 02:16:27.000
|
||
|
here we
|
||
|
|
||
|
02:16:27.000 --> 02:16:29.000
|
||
|
estimate that low to moderate
|
||
|
|
||
|
02:16:29.000 --> 02:16:31.000
|
||
|
coverage
|
||
|
|
||
|
02:16:31.000 --> 02:16:33.000
|
||
|
HPV vaccination causes
|
||
|
|
||
|
02:16:33.000 --> 02:16:35.000
|
||
|
between
|
||
|
|
||
|
02:16:35.000 --> 02:16:37.000
|
||
|
5.5 and
|
||
|
|
||
|
02:16:37.000 --> 02:16:39.000
|
||
|
36.7 percent change
|
||
|
|
||
|
02:16:39.000 --> 02:16:41.000
|
||
|
in the genital HPV-type
|
||
|
|
||
|
02:16:41.000 --> 02:16:43.000
|
||
|
distribution
|
||
|
|
||
|
02:16:43.000 --> 02:16:45.000
|
||
|
we estimate
|
||
|
|
||
|
02:16:45.000 --> 02:16:47.000
|
||
|
that a
|
||
|
|
||
|
02:16:47.000 --> 02:16:49.000
|
||
|
low to moderate change
|
||
|
|
||
|
02:16:49.000 --> 02:16:51.000
|
||
|
from moderate coverage of HPV
|
||
|
|
||
|
02:16:51.000 --> 02:16:53.000
|
||
|
vaccination causes
|
||
|
|
||
|
02:16:53.000 --> 02:16:55.000
|
||
|
a 25 to 36 percent
|
||
|
|
||
|
02:16:55.000 --> 02:16:57.000
|
||
|
change in the genital HPV-type
|
||
|
|
||
|
02:16:57.000 --> 02:16:59.000
|
||
|
distributions
|
||
|
|
||
|
02:16:59.000 --> 02:17:01.000
|
||
|
in HPV vaccination communities
|
||
|
|
||
|
02:17:01.000 --> 02:17:03.000
|
||
|
the change mostly stems
|
||
|
|
||
|
02:17:03.000 --> 02:17:05.000
|
||
|
from a decrease in the occurrence
|
||
|
|
||
|
02:17:05.000 --> 02:17:07.000
|
||
|
of high-achogenicity
|
||
|
|
||
|
02:17:07.000 --> 02:17:09.000
|
||
|
vaccine-targeted HPV-types
|
||
|
|
||
|
02:17:09.000 --> 02:17:11.000
|
||
|
but particularly when
|
||
|
|
||
|
02:17:11.000 --> 02:17:13.000
|
||
|
implemented general
|
||
|
|
||
|
02:17:13.000 --> 02:17:15.000
|
||
|
neutral also a
|
||
|
|
||
|
02:17:15.000 --> 02:17:17.000
|
||
|
12 to 20 percent shift
|
||
|
|
||
|
02:17:17.000 --> 02:17:19.000
|
||
|
in low-achogenic
|
||
|
|
||
|
02:17:19.000 --> 02:17:21.000
|
||
|
non-vaccine-targeted
|
||
|
|
||
|
02:17:21.000 --> 02:17:23.000
|
||
|
HPV-types is observed
|
||
|
|
||
|
02:17:23.000 --> 02:17:25.000
|
||
|
while the eradication
|
||
|
|
||
|
02:17:25.000 --> 02:17:27.000
|
||
|
of HPV 16-18-31-45 will
|
||
|
|
||
|
02:17:27.000 --> 02:17:29.000
|
||
|
eliminate most cervical cancers
|
||
|
|
||
|
02:17:29.000 --> 02:17:31.000
|
||
|
these are not the
|
||
|
|
||
|
02:17:31.000 --> 02:17:33.000
|
||
|
seroprevalence numbers that were listed by them
|
||
|
|
||
|
02:17:33.000 --> 02:17:35.000
|
||
|
in the previous discussion
|
||
|
|
||
|
02:17:35.000 --> 02:17:37.000
|
||
|
they actually said
|
||
|
|
||
|
02:17:37.000 --> 02:17:39.000
|
||
|
what did they say
|
||
|
|
||
|
02:17:39.000 --> 02:17:41.000
|
||
|
618 something something
|
||
|
|
||
|
02:17:41.000 --> 02:17:43.000
|
||
|
and that's
|
||
|
|
||
|
02:17:43.000 --> 02:17:45.000
|
||
|
right so you didn't see those because there was so much
|
||
|
|
||
|
02:17:45.000 --> 02:17:47.000
|
||
|
by smoking
|
||
|
|
||
|
02:17:47.000 --> 02:17:49.000
|
||
|
surf risk
|
||
|
|
||
|
02:17:49.000 --> 02:17:51.000
|
||
|
surf risk
|
||
|
|
||
|
02:17:51.000 --> 02:17:53.000
|
||
|
rare situation
|
||
|
|
||
|
02:17:53.000 --> 02:17:55.000
|
||
|
listen to the numbers she says here
|
||
|
|
||
|
02:17:55.000 --> 02:17:57.000
|
||
|
that's possible but these are
|
||
|
|
||
|
02:17:57.000 --> 02:17:59.000
|
||
|
okay so there are over 100 different types of
|
||
|
|
||
|
02:17:59.000 --> 02:18:01.000
|
||
|
HPV not all of them cause health problems
|
||
|
|
||
|
02:18:01.000 --> 02:18:03.000
|
||
|
some kinds may cause problems like
|
||
|
|
||
|
02:18:03.000 --> 02:18:05.000
|
||
|
genital wards some kinds can also cause cancer
|
||
|
|
||
|
02:18:05.000 --> 02:18:07.000
|
||
|
of the cervix vagina vulva or anus
|
||
|
|
||
|
02:18:07.000 --> 02:18:09.000
|
||
|
most of these problems are caused by types
|
||
|
|
||
|
02:18:09.000 --> 02:18:11.000
|
||
|
6, 11, 16, or 18
|
||
|
|
||
|
02:18:11.000 --> 02:18:13.000
|
||
|
November 1st FDA
|
||
|
|
||
|
02:18:13.000 --> 02:18:15.000
|
||
|
6, 11, 16, or 18
|
||
|
|
||
|
02:18:15.000 --> 02:18:17.000
|
||
|
in a class of high-risk low risk
|
||
|
|
||
|
02:18:17.000 --> 02:18:19.000
|
||
|
no risk
|
||
|
|
||
|
02:18:19.000 --> 02:18:21.000
|
||
|
no surf risk so what are they talking about then right
|
||
|
|
||
|
02:18:21.000 --> 02:18:23.000
|
||
|
1, 2, 3, 4, 5, 6, 7, 8, 9
|
||
|
|
||
|
02:18:23.000 --> 02:18:25.000
|
||
|
what this paper
|
||
|
|
||
|
02:18:25.000 --> 02:18:27.000
|
||
|
that they're reading
|
||
|
|
||
|
02:18:27.000 --> 02:18:29.000
|
||
|
in the conclusion says that
|
||
|
|
||
|
02:18:29.000 --> 02:18:33.000
|
||
|
while eradication of 16, 18,
|
||
|
|
||
|
02:18:33.000 --> 02:18:35.000
|
||
|
31, and 45 will eliminate
|
||
|
|
||
|
02:18:35.000 --> 02:18:37.000
|
||
|
most cervical cancers
|
||
|
|
||
|
02:18:37.000 --> 02:18:39.000
|
||
|
it is tempting to suggest that an increase
|
||
|
|
||
|
02:18:39.000 --> 02:18:43.000
|
||
|
of 33, 35, 51, 52, 56, and 66
|
||
|
|
||
|
02:18:43.000 --> 02:18:45.000
|
||
|
or the like
|
||
|
|
||
|
02:18:45.000 --> 02:18:47.000
|
||
|
with increased virulence might cause
|
||
|
|
||
|
02:18:47.000 --> 02:18:49.000
|
||
|
a risk of HPV related cancers in the future
|
||
|
|
||
|
02:18:49.000 --> 02:18:51.000
|
||
|
in other words
|
||
|
|
||
|
02:18:51.000 --> 02:18:53.000
|
||
|
eradicating some
|
||
|
|
||
|
02:18:53.000 --> 02:18:55.000
|
||
|
doesn't guarantee that the others
|
||
|
|
||
|
02:18:55.000 --> 02:18:57.000
|
||
|
won't cause cancer
|
||
|
|
||
|
02:18:57.000 --> 02:18:59.000
|
||
|
the correlation
|
||
|
|
||
|
02:18:59.000 --> 02:19:01.000
|
||
|
of these
|
||
|
|
||
|
02:19:01.000 --> 02:19:03.000
|
||
|
does not preclude
|
||
|
|
||
|
02:19:03.000 --> 02:19:05.000
|
||
|
the role of these
|
||
|
|
||
|
02:19:05.000 --> 02:19:07.000
|
||
|
in those same cancers
|
||
|
|
||
|
02:19:07.000 --> 02:19:09.000
|
||
|
it wouldn't surprise me if a lot of times
|
||
|
|
||
|
02:19:09.000 --> 02:19:11.000
|
||
|
when 16, 18, 31, 45,
|
||
|
|
||
|
02:19:11.000 --> 02:19:13.000
|
||
|
1, 6, whichever one you want to do
|
||
|
|
||
|
02:19:13.000 --> 02:19:15.000
|
||
|
is associated with cancer
|
||
|
|
||
|
02:19:15.000 --> 02:19:17.000
|
||
|
they don't do a complete screen
|
||
|
|
||
|
02:19:17.000 --> 02:19:19.000
|
||
|
to show definitively
|
||
|
|
||
|
02:19:19.000 --> 02:19:21.000
|
||
|
that none of these other sero types
|
||
|
|
||
|
02:19:21.000 --> 02:19:23.000
|
||
|
are present
|
||
|
|
||
|
02:19:23.000 --> 02:19:25.000
|
||
|
in this paper they fall woefully short
|
||
|
|
||
|
02:19:25.000 --> 02:19:27.000
|
||
|
of measuring 100, right?
|
||
|
|
||
|
02:19:27.000 --> 02:19:29.000
|
||
|
they only do like 10
|
||
|
|
||
|
02:19:33.000 --> 02:19:35.000
|
||
|
so the really crazy thing to see here
|
||
|
|
||
|
02:19:35.000 --> 02:19:37.000
|
||
|
ladies and gentlemen in this paper
|
||
|
|
||
|
02:19:37.000 --> 02:19:39.000
|
||
|
is this number
|
||
|
|
||
|
02:19:39.000 --> 02:19:41.000
|
||
|
that they use
|
||
|
|
||
|
02:19:43.000 --> 02:19:45.000
|
||
|
because the actual results
|
||
|
|
||
|
02:19:45.000 --> 02:19:47.000
|
||
|
of the paper
|
||
|
|
||
|
02:19:47.000 --> 02:19:49.000
|
||
|
are extraordinary
|
||
|
|
||
|
02:19:49.000 --> 02:19:51.000
|
||
|
where is it?
|
||
|
|
||
|
02:19:53.000 --> 02:19:55.000
|
||
|
I'm going to find this one
|
||
|
|
||
|
02:19:55.000 --> 02:19:57.000
|
||
|
number
|
||
|
|
||
|
02:19:57.000 --> 02:19:59.000
|
||
|
in the results
|
||
|
|
||
|
02:19:59.000 --> 02:20:01.000
|
||
|
that will just blow your mind
|
||
|
|
||
|
02:20:01.000 --> 02:20:03.000
|
||
|
because I do actually think
|
||
|
|
||
|
02:20:03.000 --> 02:20:05.000
|
||
|
that this is what they say
|
||
|
|
||
|
02:20:05.000 --> 02:20:07.000
|
||
|
in the paper
|
||
|
|
||
|
02:20:07.000 --> 02:20:09.000
|
||
|
in this discussion
|
||
|
|
||
|
02:20:13.000 --> 02:20:15.000
|
||
|
where is it?
|
||
|
|
||
|
02:20:15.000 --> 02:20:17.000
|
||
|
come on Jay, find it
|
||
|
|
||
|
02:20:17.000 --> 02:20:19.000
|
||
|
at least in your time like this
|
||
|
|
||
|
02:20:23.000 --> 02:20:25.000
|
||
|
maybe it's right away in the beginning
|
||
|
|
||
|
02:20:25.000 --> 02:20:27.000
|
||
|
it's so close to the start
|
||
|
|
||
|
02:20:27.000 --> 02:20:29.000
|
||
|
maybe that's why I found it right away
|
||
|
|
||
|
02:20:33.000 --> 02:20:35.000
|
||
|
so where is this data here
|
||
|
|
||
|
02:20:35.000 --> 02:20:37.000
|
||
|
we need that
|
||
|
|
||
|
02:20:37.000 --> 02:20:39.000
|
||
|
we need this
|
||
|
|
||
|
02:20:39.000 --> 02:20:41.000
|
||
|
yes here
|
||
|
|
||
|
02:20:41.000 --> 02:20:43.000
|
||
|
HPV prevalence
|
||
|
|
||
|
02:20:43.000 --> 02:20:45.000
|
||
|
oh no this was a different paper
|
||
|
|
||
|
02:20:45.000 --> 02:20:47.000
|
||
|
okay sorry I'm looking for something
|
||
|
|
||
|
02:20:47.000 --> 02:20:49.000
|
||
|
that's not in this paper
|
||
|
|
||
|
02:20:49.000 --> 02:20:51.000
|
||
|
I'm going to show you that paper tomorrow
|
||
|
|
||
|
02:20:51.000 --> 02:20:53.000
|
||
|
I apologize
|
||
|
|
||
|
02:20:53.000 --> 02:20:55.000
|
||
|
I don't think it's this paper
|
||
|
|
||
|
02:20:55.000 --> 02:20:57.000
|
||
|
no it's not it can't be this paper
|
||
|
|
||
|
02:20:57.000 --> 02:20:59.000
|
||
|
it is a paper that they cited
|
||
|
|
||
|
02:20:59.000 --> 02:21:01.000
|
||
|
which paper did they cite
|
||
|
|
||
|
02:21:01.000 --> 02:21:03.000
|
||
|
that I looked that up in
|
||
|
|
||
|
02:21:07.000 --> 02:21:09.000
|
||
|
what paper was it?
|
||
|
|
||
|
02:21:09.000 --> 02:21:11.000
|
||
|
it's one of these first here
|
||
|
|
||
|
02:21:11.000 --> 02:21:13.000
|
||
|
documenting its health
|
||
|
|
||
|
02:21:13.000 --> 02:21:15.000
|
||
|
infectious agent
|
||
|
|
||
|
02:21:15.000 --> 02:21:17.000
|
||
|
eight years what is this one?
|
||
|
|
||
|
02:21:17.000 --> 02:21:19.000
|
||
|
nineteen
|
||
|
|
||
|
02:21:19.000 --> 02:21:21.000
|
||
|
is that the one? no
|
||
|
|
||
|
02:21:21.000 --> 02:21:23.000
|
||
|
which one
|
||
|
|
||
|
02:21:23.000 --> 02:21:25.000
|
||
|
is it?
|
||
|
|
||
|
02:21:25.000 --> 02:21:27.000
|
||
|
okay well anyway
|
||
|
|
||
|
02:21:27.000 --> 02:21:29.000
|
||
|
there's a paper that I wanted to look at
|
||
|
|
||
|
02:21:29.000 --> 02:21:31.000
|
||
|
that I won't look at now
|
||
|
|
||
|
02:21:31.000 --> 02:21:33.000
|
||
|
because it's taken me too long to find it
|
||
|
|
||
|
02:21:33.000 --> 02:21:35.000
|
||
|
which basically is one of the papers
|
||
|
|
||
|
02:21:35.000 --> 02:21:37.000
|
||
|
that that cell micro paper
|
||
|
|
||
|
02:21:37.000 --> 02:21:39.000
|
||
|
has providing proof
|
||
|
|
||
|
02:21:39.000 --> 02:21:41.000
|
||
|
that vaccination reduces
|
||
|
|
||
|
02:21:41.000 --> 02:21:43.000
|
||
|
cancer
|
||
|
|
||
|
02:21:43.000 --> 02:21:45.000
|
||
|
and in that paper
|
||
|
|
||
|
02:21:45.000 --> 02:21:47.000
|
||
|
the results of the
|
||
|
|
||
|
02:21:47.000 --> 02:21:49.000
|
||
|
let's say significant
|
||
|
|
||
|
02:21:49.000 --> 02:21:51.000
|
||
|
result of the vaccine
|
||
|
|
||
|
02:21:51.000 --> 02:21:53.000
|
||
|
is a 19%
|
||
|
|
||
|
02:21:53.000 --> 02:21:55.000
|
||
|
increase in
|
||
|
|
||
|
02:21:55.000 --> 02:21:57.000
|
||
|
cervical cancer
|
||
|
|
||
|
02:21:57.000 --> 02:21:59.000
|
||
|
in the unvaccinated group
|
||
|
|
||
|
02:21:59.000 --> 02:22:01.000
|
||
|
with a 95%
|
||
|
|
||
|
02:22:01.000 --> 02:22:03.000
|
||
|
confidence interval which extends above
|
||
|
|
||
|
02:22:03.000 --> 02:22:05.000
|
||
|
and below one
|
||
|
|
||
|
02:22:05.000 --> 02:22:07.000
|
||
|
basically means that by their
|
||
|
|
||
|
02:22:07.000 --> 02:22:09.000
|
||
|
confidence interval
|
||
|
|
||
|
02:22:09.000 --> 02:22:11.000
|
||
|
they're pretty sure with a 95%
|
||
|
|
||
|
02:22:11.000 --> 02:22:13.000
|
||
|
possibility they're pretty sure
|
||
|
|
||
|
02:22:13.000 --> 02:22:15.000
|
||
|
that either the vaccine
|
||
|
|
||
|
02:22:15.000 --> 02:22:17.000
|
||
|
reduces
|
||
|
|
||
|
02:22:17.000 --> 02:22:19.000
|
||
|
or increases the prevalence of
|
||
|
|
||
|
02:22:19.000 --> 02:22:21.000
|
||
|
cancer in those that receive it
|
||
|
|
||
|
02:22:21.000 --> 02:22:23.000
|
||
|
because again one
|
||
|
|
||
|
02:22:23.000 --> 02:22:25.000
|
||
|
is equivalence
|
||
|
|
||
|
02:22:25.000 --> 02:22:27.000
|
||
|
below one is that
|
||
|
|
||
|
02:22:27.000 --> 02:22:29.000
|
||
|
the vaccine causes
|
||
|
|
||
|
02:22:29.000 --> 02:22:31.000
|
||
|
more people to get cancer
|
||
|
|
||
|
02:22:31.000 --> 02:22:33.000
|
||
|
and above one
|
||
|
|
||
|
02:22:33.000 --> 02:22:35.000
|
||
|
means that it reduces their
|
||
|
|
||
|
02:22:35.000 --> 02:22:37.000
|
||
|
possibility of having cancer
|
||
|
|
||
|
02:22:37.000 --> 02:22:39.000
|
||
|
and their confidence
|
||
|
|
||
|
02:22:39.000 --> 02:22:41.000
|
||
|
intervals in their result
|
||
|
|
||
|
02:22:41.000 --> 02:22:43.000
|
||
|
of 1.19
|
||
|
|
||
|
02:22:43.000 --> 02:22:45.000
|
||
|
is a confidence interval
|
||
|
|
||
|
02:22:45.000 --> 02:22:47.000
|
||
|
that extends from one point
|
||
|
|
||
|
02:22:47.000 --> 02:22:49.000
|
||
|
something
|
||
|
|
||
|
02:22:49.000 --> 02:22:51.000
|
||
|
down to 0.8
|
||
|
|
||
|
02:22:51.000 --> 02:22:53.000
|
||
|
which means that
|
||
|
|
||
|
02:22:53.000 --> 02:22:55.000
|
||
|
they're about 95% sure
|
||
|
|
||
|
02:22:55.000 --> 02:22:57.000
|
||
|
that it either works or it doesn't
|
||
|
|
||
|
02:22:57.000 --> 02:22:59.000
|
||
|
and that is the one
|
||
|
|
||
|
02:22:59.000 --> 02:23:01.000
|
||
|
paper that is cited
|
||
|
|
||
|
02:23:01.000 --> 02:23:03.000
|
||
|
by this cell micro paper
|
||
|
|
||
|
02:23:03.000 --> 02:23:05.000
|
||
|
as you know these things
|
||
|
|
||
|
02:23:05.000 --> 02:23:07.000
|
||
|
are great at preventing cancer
|
||
|
|
||
|
02:23:07.000 --> 02:23:09.000
|
||
|
the same thing that
|
||
|
|
||
|
02:23:09.000 --> 02:23:11.000
|
||
|
Vincent started this whole discussion with
|
||
|
|
||
|
02:23:11.000 --> 02:23:13.000
|
||
|
that these are great strategy
|
||
|
|
||
|
02:23:13.000 --> 02:23:15.000
|
||
|
for
|
||
|
|
||
|
02:23:15.000 --> 02:23:17.000
|
||
|
preventing cancer.
|
||
|
|
||
|
02:23:17.000 --> 02:23:19.000
|
||
|
We don't even have
|
||
|
|
||
|
02:23:19.000 --> 02:23:21.000
|
||
|
people that are old enough
|
||
|
|
||
|
02:23:21.000 --> 02:23:23.000
|
||
|
to produce the data
|
||
|
|
||
|
02:23:23.000 --> 02:23:25.000
|
||
|
that's supposed to be there.
|
||
|
|
||
|
02:23:25.000 --> 02:23:27.000
|
||
|
We're just now getting to the point where
|
||
|
|
||
|
02:23:27.000 --> 02:23:29.000
|
||
|
any teenager that was vaccinated
|
||
|
|
||
|
02:23:29.000 --> 02:23:31.000
|
||
|
with this horrible idea of a product
|
||
|
|
||
|
02:23:31.000 --> 02:23:33.000
|
||
|
is getting into the range
|
||
|
|
||
|
02:23:33.000 --> 02:23:35.000
|
||
|
where they might develop it
|
||
|
|
||
|
02:23:39.000 --> 02:23:41.000
|
||
|
I'm going to kind of wrap it up here
|
||
|
|
||
|
02:23:41.000 --> 02:23:43.000
|
||
|
because I don't think there's any reason
|
||
|
|
||
|
02:23:43.000 --> 02:23:45.000
|
||
|
to let these people talk anymore
|
||
|
|
||
|
02:23:45.000 --> 02:23:47.000
|
||
|
but they might say a few more interesting things
|
||
|
|
||
|
02:23:47.000 --> 02:23:49.000
|
||
|
9, 10, 11, 12, 13 high risk
|
||
|
|
||
|
02:23:49.000 --> 02:23:51.000
|
||
|
so not all the high risk are in the vaccine
|
||
|
|
||
|
02:23:51.000 --> 02:23:53.000
|
||
|
because I think there's not enough infections
|
||
|
|
||
|
02:23:53.000 --> 02:23:55.000
|
||
|
but maybe that could change, right?
|
||
|
|
||
|
02:23:55.000 --> 02:23:57.000
|
||
|
Yeah and it's like
|
||
|
|
||
|
02:23:57.000 --> 02:23:59.000
|
||
|
we'll talk about HPV causing it
|
||
|
|
||
|
02:23:59.000 --> 02:24:01.000
|
||
|
but if you go back 30 or 40 years
|
||
|
|
||
|
02:24:01.000 --> 02:24:03.000
|
||
|
HPV was not really a big topic of conversation
|
||
|
|
||
|
02:24:03.000 --> 02:24:05.000
|
||
|
for oral for angel cancer because the overwhelming majority
|
||
|
|
||
|
02:24:05.000 --> 02:24:07.000
|
||
|
of the vaccine when that's gotten wide enough uptake
|
||
|
|
||
|
02:24:07.000 --> 02:24:09.000
|
||
|
will get to a point where we'll say
|
||
|
|
||
|
02:24:09.000 --> 02:24:11.000
|
||
|
okay we got most of it and now they're these
|
||
|
|
||
|
02:24:11.000 --> 02:24:13.000
|
||
|
remaining ones and as I say that might be time
|
||
|
|
||
|
02:24:13.000 --> 02:24:15.000
|
||
|
to add more to the vaccine
|
||
|
|
||
|
02:24:15.000 --> 02:24:17.000
|
||
|
but this is certainly proven a very very
|
||
|
|
||
|
02:24:17.000 --> 02:24:19.000
|
||
|
successful strategy
|
||
|
|
||
|
02:24:19.000 --> 02:24:21.000
|
||
|
and that's one of the issues for looking at
|
||
|
|
||
|
02:24:21.000 --> 02:24:23.000
|
||
|
this change in the if you'll allow it
|
||
|
|
||
|
02:24:23.000 --> 02:24:25.000
|
||
|
Dixen ecology of the
|
||
|
|
||
|
02:24:25.000 --> 02:24:27.000
|
||
|
other the other serotypes
|
||
|
|
||
|
02:24:27.000 --> 02:24:29.000
|
||
|
All right so I'm going to
|
||
|
|
||
|
02:24:29.000 --> 02:24:31.000
|
||
|
head to the discussion now because I find it easier
|
||
|
|
||
|
02:24:31.000 --> 02:24:33.000
|
||
|
to summarize the results from there
|
||
|
|
||
|
02:24:33.000 --> 02:24:35.000
|
||
|
so basically just to repeat
|
||
|
|
||
|
02:24:35.000 --> 02:24:37.000
|
||
|
so we find depletion of the high oncogene
|
||
|
|
||
|
02:24:37.000 --> 02:24:39.000
|
||
|
vaccine targeted type 16, 18, 31, 45
|
||
|
|
||
|
02:24:39.000 --> 02:24:41.000
|
||
|
and both gender neutral and girls only
|
||
|
|
||
|
02:24:41.000 --> 02:24:43.000
|
||
|
vaccination four years and six years after
|
||
|
|
||
|
02:24:43.000 --> 02:24:45.000
|
||
|
vaccination but eight years but at eight years
|
||
|
|
||
|
02:24:45.000 --> 02:24:47.000
|
||
|
they only see it in gender neutral but what they say is
|
||
|
|
||
|
02:24:47.000 --> 02:24:49.000
|
||
|
our most important finding that increased
|
||
|
|
||
|
02:24:49.000 --> 02:24:51.000
|
||
|
oncogenic HPV's diversity from 48 years
|
||
|
|
||
|
02:24:51.000 --> 02:24:53.000
|
||
|
post vaccination exclusively in gender neutral
|
||
|
|
||
|
02:24:53.000 --> 02:24:55.000
|
||
|
communities even though the high risk
|
||
|
|
||
|
02:24:55.000 --> 02:24:57.000
|
||
|
vaccine targeted
|
||
|
|
||
|
02:24:57.000 --> 02:24:59.000
|
||
|
viruses have been decreased in those
|
||
|
|
||
|
02:24:59.000 --> 02:25:01.000
|
||
|
communities and they write this is the first
|
||
|
|
||
|
02:25:01.000 --> 02:25:03.000
|
||
|
recorded sign of ecological niche occupation
|
||
|
|
||
|
02:25:03.000 --> 02:25:05.000
|
||
|
by the non-vaccinated HPV post population
|
||
|
|
||
|
02:25:05.000 --> 02:25:07.000
|
||
|
level vaccination some of these
|
||
|
|
||
|
02:25:07.000 --> 02:25:09.000
|
||
|
sentences are tough yeah I feel like this paper
|
||
|
|
||
|
02:25:09.000 --> 02:25:11.000
|
||
|
could have used a good copy edit in some parts
|
||
|
|
||
|
02:25:11.000 --> 02:25:13.000
|
||
|
I mean that when the first recorded
|
||
|
|
||
|
02:25:13.000 --> 02:25:15.000
|
||
|
sign of ecological niche occupation by the non-vaccinated
|
||
|
|
||
|
02:25:15.000 --> 02:25:17.000
|
||
|
HPV post population level vaccination
|
||
|
|
||
|
02:25:17.000 --> 02:25:19.000
|
||
|
there's a lot of parts there yeah
|
||
|
|
||
|
02:25:19.000 --> 02:25:21.000
|
||
|
if that was the title I would have rejected the paper
|
||
|
|
||
|
02:25:21.000 --> 02:25:23.000
|
||
|
the second quote sentence of the introduction
|
||
|
|
||
|
02:25:23.000 --> 02:25:25.000
|
||
|
isn't a sentence until you take out the word
|
||
|
|
||
|
02:25:25.000 --> 02:25:27.000
|
||
|
albeit yes yes there were sentences
|
||
|
|
||
|
02:25:27.000 --> 02:25:29.000
|
||
|
that I read four or five times there were several like that
|
||
|
|
||
|
02:25:29.000 --> 02:25:31.000
|
||
|
that I came to oh I see what they mean now
|
||
|
|
||
|
02:25:31.000 --> 02:25:33.000
|
||
|
okay but so they can't write a paper
|
||
|
|
||
|
02:25:33.000 --> 02:25:35.000
|
||
|
the paper is written in a very very
|
||
|
|
||
|
02:25:35.000 --> 02:25:37.000
|
||
|
inaccurate and imprecise way
|
||
|
|
||
|
02:25:37.000 --> 02:25:39.000
|
||
|
but they're still sure
|
||
|
|
||
|
02:25:39.000 --> 02:25:41.000
|
||
|
that they understand the implications
|
||
|
|
||
|
02:25:41.000 --> 02:25:43.000
|
||
|
of the paper even though they haven't
|
||
|
|
||
|
02:25:43.000 --> 02:25:45.000
|
||
|
even stated that the data
|
||
|
|
||
|
02:25:45.000 --> 02:25:47.000
|
||
|
that's that they're using to make
|
||
|
|
||
|
02:25:47.000 --> 02:25:51.000
|
||
|
their conclusions is synthetic
|
||
|
|
||
|
02:25:51.000 --> 02:25:53.000
|
||
|
did you
|
||
|
|
||
|
02:25:53.000 --> 02:25:55.000
|
||
|
did you I mean
|
||
|
|
||
|
02:25:55.000 --> 02:25:59.000
|
||
|
where did I put that paper now here
|
||
|
|
||
|
02:25:59.000 --> 02:26:03.000
|
||
|
I suppose I got rid of it right I closed it
|
||
|
|
||
|
02:26:03.000 --> 02:26:05.000
|
||
|
did I close that
|
||
|
|
||
|
02:26:05.000 --> 02:26:07.000
|
||
|
I guess I closed that window
|
||
|
|
||
|
02:26:07.000 --> 02:26:09.000
|
||
|
hold on let me pull this up again
|
||
|
|
||
|
02:26:09.000 --> 02:26:11.000
|
||
|
PDF
|
||
|
|
||
|
02:26:11.000 --> 02:26:15.000
|
||
|
we're here
|
||
|
|
||
|
02:26:15.000 --> 02:26:17.000
|
||
|
so let's see
|
||
|
|
||
|
02:26:17.000 --> 02:26:19.000
|
||
|
where was this
|
||
|
|
||
|
02:26:19.000 --> 02:26:21.000
|
||
|
paper the
|
||
|
|
||
|
02:26:21.000 --> 02:26:25.000
|
||
|
the methodology here right so
|
||
|
|
||
|
02:26:25.000 --> 02:26:27.000
|
||
|
that was this one this is where I read it
|
||
|
|
||
|
02:26:27.000 --> 02:26:29.000
|
||
|
I mean I'm not
|
||
|
|
||
|
02:26:29.000 --> 02:26:31.000
|
||
|
for figure three they had to do a
|
||
|
|
||
|
02:26:31.000 --> 02:26:33.000
|
||
|
simulation of community prevalence
|
||
|
|
||
|
02:26:33.000 --> 02:26:35.000
|
||
|
distribution by vaccination strategy
|
||
|
|
||
|
02:26:35.000 --> 02:26:37.000
|
||
|
so finally to comprehensive
|
||
|
|
||
|
02:26:37.000 --> 02:26:39.000
|
||
|
evaluate the community level
|
||
|
|
||
|
02:26:39.000 --> 02:26:41.000
|
||
|
HPV type diversity
|
||
|
|
||
|
02:26:41.000 --> 02:26:43.000
|
||
|
distribution between the trial arms
|
||
|
|
||
|
02:26:43.000 --> 02:26:45.000
|
||
|
they use this
|
||
|
|
||
|
02:26:45.000 --> 02:26:47.000
|
||
|
general independent
|
||
|
|
||
|
02:26:47.000 --> 02:26:49.000
|
||
|
or graphic independence network
|
||
|
|
||
|
02:26:49.000 --> 02:26:51.000
|
||
|
modeling
|
||
|
|
||
|
02:26:51.000 --> 02:26:53.000
|
||
|
and they simulated a
|
||
|
|
||
|
02:26:53.000 --> 02:26:55.000
|
||
|
data set
|
||
|
|
||
|
02:26:55.000 --> 02:26:57.000
|
||
|
simulated a distribution
|
||
|
|
||
|
02:26:57.000 --> 02:26:59.000
|
||
|
for a hundred thousand individuals
|
||
|
|
||
|
02:26:59.000 --> 02:27:03.000
|
||
|
and then they made their figure three
|
||
|
|
||
|
02:27:03.000 --> 02:27:07.000
|
||
|
based on that this figure three is based on that
|
||
|
|
||
|
02:27:07.000 --> 02:27:11.000
|
||
|
synthetic community level distribution
|
||
|
|
||
|
02:27:11.000 --> 02:27:15.000
|
||
|
it's beta diversity using synthetic data
|
||
|
|
||
|
02:27:15.000 --> 02:27:19.000
|
||
|
it's not really an
|
||
|
|
||
|
02:27:19.000 --> 02:27:21.000
|
||
|
observation that has much significance
|
||
|
|
||
|
02:27:21.000 --> 02:27:23.000
|
||
|
except for when they extended it using
|
||
|
|
||
|
02:27:23.000 --> 02:27:27.000
|
||
|
synthetic data
|
||
|
|
||
|
02:27:27.000 --> 02:27:31.000
|
||
|
that's the part that's most frustrating
|
||
|
|
||
|
02:27:31.000 --> 02:27:35.000
|
||
|
this data from the actual communities was not sufficient
|
||
|
|
||
|
02:27:35.000 --> 02:27:39.000
|
||
|
for them to demonstrate the effect that they claim to have observed
|
||
|
|
||
|
02:27:39.000 --> 02:27:41.000
|
||
|
that's really important
|
||
|
|
||
|
02:27:41.000 --> 02:27:43.000
|
||
|
it's really important because
|
||
|
|
||
|
02:27:43.000 --> 02:27:45.000
|
||
|
these these twib people
|
||
|
|
||
|
02:27:45.000 --> 02:27:47.000
|
||
|
aren't adequately
|
||
|
|
||
|
02:27:47.000 --> 02:27:49.000
|
||
|
describing the limitations of the paper
|
||
|
|
||
|
02:27:49.000 --> 02:27:51.000
|
||
|
even as they
|
||
|
|
||
|
02:27:51.000 --> 02:27:53.000
|
||
|
they pretend to have this discussion
|
||
|
|
||
|
02:27:53.000 --> 02:27:55.000
|
||
|
about what's wrong with it or
|
||
|
|
||
|
02:27:55.000 --> 02:27:57.000
|
||
|
they're not very good writers or they should have written it better
|
||
|
|
||
|
02:27:57.000 --> 02:27:59.000
|
||
|
it needs a copy editor
|
||
|
|
||
|
02:28:01.000 --> 02:28:03.000
|
||
|
it doesn't need a copy editor
|
||
|
|
||
|
02:28:03.000 --> 02:28:05.000
|
||
|
it needs somebody to adequately
|
||
|
|
||
|
02:28:05.000 --> 02:28:07.000
|
||
|
explain how much
|
||
|
|
||
|
02:28:07.000 --> 02:28:09.000
|
||
|
charlatanism and enchant
|
||
|
|
||
|
02:28:09.000 --> 02:28:11.000
|
||
|
and is being cast by such a paper
|
||
|
|
||
|
02:28:13.000 --> 02:28:15.000
|
||
|
how very little
|
||
|
|
||
|
02:28:15.000 --> 02:28:17.000
|
||
|
forward progress is made
|
||
|
|
||
|
02:28:17.000 --> 02:28:19.000
|
||
|
by such a paper
|
||
|
|
||
|
02:28:19.000 --> 02:28:21.000
|
||
|
how it's vital
|
||
|
|
||
|
02:28:21.000 --> 02:28:23.000
|
||
|
that no forward progress
|
||
|
|
||
|
02:28:23.000 --> 02:28:25.000
|
||
|
is made in this field in order
|
||
|
|
||
|
02:28:25.000 --> 02:28:27.000
|
||
|
for this mythology to be sustained
|
||
|
|
||
|
02:28:29.000 --> 02:28:31.000
|
||
|
and that's the role that this clown
|
||
|
|
||
|
02:28:31.000 --> 02:28:33.000
|
||
|
show plays
|
||
|
|
||
|
02:28:33.000 --> 02:28:35.000
|
||
|
that this handler
|
||
|
|
||
|
02:28:35.000 --> 02:28:37.000
|
||
|
is using these people for
|
||
|
|
||
|
02:28:37.000 --> 02:28:39.000
|
||
|
is using
|
||
|
|
||
|
02:28:39.000 --> 02:28:41.000
|
||
|
fame, perceived
|
||
|
|
||
|
02:28:41.000 --> 02:28:43.000
|
||
|
fame, perceived
|
||
|
|
||
|
02:28:43.000 --> 02:28:45.000
|
||
|
importance, perceived
|
||
|
|
||
|
02:28:45.000 --> 02:28:47.000
|
||
|
significance on the internet
|
||
|
|
||
|
02:28:47.000 --> 02:28:49.000
|
||
|
you know you're part of
|
||
|
|
||
|
02:28:49.000 --> 02:28:51.000
|
||
|
twiv, so you've got an obligation
|
||
|
|
||
|
02:28:51.000 --> 02:28:53.000
|
||
|
to get this right
|
||
|
|
||
|
02:28:53.000 --> 02:28:55.000
|
||
|
and this is the moderator right here
|
||
|
|
||
|
02:28:55.000 --> 02:28:57.000
|
||
|
the guy who is responsible for the first
|
||
|
|
||
|
02:28:57.000 --> 02:28:59.000
|
||
|
infectious clone of an RNA virus
|
||
|
|
||
|
02:28:59.000 --> 02:29:01.000
|
||
|
ever
|
||
|
|
||
|
02:29:01.000 --> 02:29:03.000
|
||
|
with his supervisor
|
||
|
|
||
|
02:29:03.000 --> 02:29:05.000
|
||
|
David Baltimore
|
||
|
|
||
|
02:29:05.000 --> 02:29:07.000
|
||
|
who I'm convinced is one of the
|
||
|
|
||
|
02:29:07.000 --> 02:29:09.000
|
||
|
granddaddy of all the liars
|
||
|
|
||
|
02:29:09.000 --> 02:29:11.000
|
||
|
in this group of people
|
||
|
|
||
|
02:29:11.000 --> 02:29:13.000
|
||
|
granddaddy of them all
|
||
|
|
||
|
02:29:13.000 --> 02:29:15.000
|
||
|
is David Baltimore
|
||
|
|
||
|
02:29:15.000 --> 02:29:17.000
|
||
|
if there's anyone who knows
|
||
|
|
||
|
02:29:17.000 --> 02:29:19.000
|
||
|
the truth about the lies
|
||
|
|
||
|
02:29:19.000 --> 02:29:21.000
|
||
|
of intramuscular injection
|
||
|
|
||
|
02:29:21.000 --> 02:29:23.000
|
||
|
and the augmenting of the immune system
|
||
|
|
||
|
02:29:23.000 --> 02:29:25.000
|
||
|
using adjuvants and recombinant proteins
|
||
|
|
||
|
02:29:25.000 --> 02:29:27.000
|
||
|
hits David Baltimore
|
||
|
|
||
|
02:29:27.000 --> 02:29:29.000
|
||
|
and his protégé
|
||
|
|
||
|
02:29:29.000 --> 02:29:31.000
|
||
|
Vincent Rancin yellow
|
||
|
|
||
|
02:29:31.000 --> 02:29:33.000
|
||
|
racking yellow
|
||
|
|
||
|
02:29:33.000 --> 02:29:37.000
|
||
|
excuse me
|
||
|
|
||
|
02:29:37.000 --> 02:29:39.000
|
||
|
that's enough of these characters I think
|
||
|
|
||
|
02:29:39.000 --> 02:29:41.000
|
||
|
let's just see if they end
|
||
|
|
||
|
02:29:41.000 --> 02:29:43.000
|
||
|
why are we looking at this because
|
||
|
|
||
|
02:29:43.000 --> 02:29:45.000
|
||
|
if other viruses arise
|
||
|
|
||
|
02:29:45.000 --> 02:29:47.000
|
||
|
to feel this niche then this could be a problem
|
||
|
|
||
|
02:29:47.000 --> 02:29:49.000
|
||
|
for vaccination and they say this has been
|
||
|
|
||
|
02:29:49.000 --> 02:29:51.000
|
||
|
observed with other viruses including hepatitis B virus right?
|
||
|
|
||
|
02:29:51.000 --> 02:29:53.000
|
||
|
SARS-CoV-2 we see antigenic variants
|
||
|
|
||
|
02:29:53.000 --> 02:29:55.000
|
||
|
arising and replacing others
|
||
|
|
||
|
02:29:55.000 --> 02:29:57.000
|
||
|
and so HPV's could have a similar pattern as well
|
||
|
|
||
|
02:29:57.000 --> 02:29:59.000
|
||
|
and in a more immediate sense
|
||
|
|
||
|
02:29:59.000 --> 02:30:01.000
|
||
|
we need to be aware of this for screening programs
|
||
|
|
||
|
02:30:01.000 --> 02:30:03.000
|
||
|
you have to make sure that your screening is specific enough
|
||
|
|
||
|
02:30:03.000 --> 02:30:05.000
|
||
|
that you're you know if you're going to say
|
||
|
|
||
|
02:30:05.000 --> 02:30:07.000
|
||
|
oh you know you've got evidence of a cancer causing virus
|
||
|
|
||
|
02:30:07.000 --> 02:30:09.000
|
||
|
this is the most awful part about it
|
||
|
|
||
|
02:30:09.000 --> 02:30:11.000
|
||
|
because essentially
|
||
|
|
||
|
02:30:11.000 --> 02:30:15.000
|
||
|
the only real public health data about
|
||
|
|
||
|
02:30:15.000 --> 02:30:17.000
|
||
|
who in papilloma virus and cancer
|
||
|
|
||
|
02:30:17.000 --> 02:30:19.000
|
||
|
is that like
|
||
|
|
||
|
02:30:19.000 --> 02:30:21.000
|
||
|
an incredible number of these cancers
|
||
|
|
||
|
02:30:21.000 --> 02:30:25.000
|
||
|
are essentially treated and avoided
|
||
|
|
||
|
02:30:25.000 --> 02:30:27.000
|
||
|
in regular screening
|
||
|
|
||
|
02:30:27.000 --> 02:30:29.000
|
||
|
and these vaccine pushing
|
||
|
|
||
|
02:30:29.000 --> 02:30:33.000
|
||
|
charlatans are saying that this is evidence
|
||
|
|
||
|
02:30:33.000 --> 02:30:35.000
|
||
|
for the paper
|
||
|
|
||
|
02:30:35.000 --> 02:30:37.000
|
||
|
argues that we might not
|
||
|
|
||
|
02:30:37.000 --> 02:30:39.000
|
||
|
need to screen as many people
|
||
|
|
||
|
02:30:39.000 --> 02:30:41.000
|
||
|
other people have argued that this means
|
||
|
|
||
|
02:30:41.000 --> 02:30:43.000
|
||
|
that we might need to screen people for different viruses
|
||
|
|
||
|
02:30:43.000 --> 02:30:45.000
|
||
|
or that we could screen them for viruses
|
||
|
|
||
|
02:30:45.000 --> 02:30:47.000
|
||
|
instead of for cancer because it's cheaper
|
||
|
|
||
|
02:30:49.000 --> 02:30:51.000
|
||
|
and here's Alan Dove
|
||
|
|
||
|
02:30:51.000 --> 02:30:53.000
|
||
|
right away running in for the
|
||
|
|
||
|
02:30:53.000 --> 02:30:55.000
|
||
|
one yard touchdown
|
||
|
|
||
|
02:30:55.000 --> 02:30:57.000
|
||
|
oh give me the ball
|
||
|
|
||
|
02:30:57.000 --> 02:30:59.000
|
||
|
I can push this one through
|
||
|
|
||
|
02:30:59.000 --> 02:31:01.000
|
||
|
and by the way
|
||
|
|
||
|
02:31:01.000 --> 02:31:05.000
|
||
|
it is absolutely disgusting
|
||
|
|
||
|
02:31:05.000 --> 02:31:07.000
|
||
|
make sure you've got the exact stereotype correct
|
||
|
|
||
|
02:31:07.000 --> 02:31:09.000
|
||
|
so that you don't have false alarms
|
||
|
|
||
|
02:31:09.000 --> 02:31:11.000
|
||
|
because you're going to have
|
||
|
|
||
|
02:31:11.000 --> 02:31:13.000
|
||
|
possibly these other these other stereotypes moving in
|
||
|
|
||
|
02:31:13.000 --> 02:31:15.000
|
||
|
another question that I would have as an economist
|
||
|
|
||
|
02:31:15.000 --> 02:31:17.000
|
||
|
here goes can a single person acquire
|
||
|
|
||
|
02:31:17.000 --> 02:31:19.000
|
||
|
several or ten different strains
|
||
|
|
||
|
02:31:19.000 --> 02:31:21.000
|
||
|
or whatever you're calling these
|
||
|
|
||
|
02:31:21.000 --> 02:31:23.000
|
||
|
variants of the couple of hours at the same time
|
||
|
|
||
|
02:31:23.000 --> 02:31:25.000
|
||
|
sure sure they can have
|
||
|
|
||
|
02:31:25.000 --> 02:31:27.000
|
||
|
ten different strains at the same time
|
||
|
|
||
|
02:31:27.000 --> 02:31:29.000
|
||
|
but we don't know how many they have
|
||
|
|
||
|
02:31:29.000 --> 02:31:31.000
|
||
|
and we assume that they only have one
|
||
|
|
||
|
02:31:31.000 --> 02:31:33.000
|
||
|
most of the time right Vincent
|
||
|
|
||
|
02:31:33.000 --> 02:31:35.000
|
||
|
we're not because the ecological
|
||
|
|
||
|
02:31:35.000 --> 02:31:37.000
|
||
|
concept of species
|
||
|
|
||
|
02:31:37.000 --> 02:31:39.000
|
||
|
is that no two species
|
||
|
|
||
|
02:31:39.000 --> 02:31:41.000
|
||
|
different can occupy the same dish
|
||
|
|
||
|
02:31:41.000 --> 02:31:43.000
|
||
|
only one species can occupy that niche
|
||
|
|
||
|
02:31:43.000 --> 02:31:45.000
|
||
|
typical co-infection with more than one type
|
||
|
|
||
|
02:31:45.000 --> 02:31:47.000
|
||
|
is common especially among young women
|
||
|
|
||
|
02:31:47.000 --> 02:31:49.000
|
||
|
common so that means common
|
||
|
|
||
|
02:31:49.000 --> 02:31:51.000
|
||
|
well then how in the world do they know
|
||
|
|
||
|
02:31:51.000 --> 02:31:53.000
|
||
|
that these oncogenic varieties
|
||
|
|
||
|
02:31:53.000 --> 02:31:55.000
|
||
|
are responsible if it's very common
|
||
|
|
||
|
02:31:55.000 --> 02:31:57.000
|
||
|
to have many serotypes
|
||
|
|
||
|
02:31:57.000 --> 02:31:59.000
|
||
|
on board
|
||
|
|
||
|
02:31:59.000 --> 02:32:01.000
|
||
|
these are not species
|
||
|
|
||
|
02:32:01.000 --> 02:32:03.000
|
||
|
they're varieties of the same type types
|
||
|
|
||
|
02:32:03.000 --> 02:32:05.000
|
||
|
so the use of that word ecological
|
||
|
|
||
|
02:32:05.000 --> 02:32:07.000
|
||
|
applies to species I'm sorry but that's a strict definition
|
||
|
|
||
|
02:32:07.000 --> 02:32:09.000
|
||
|
really? and that's exactly
|
||
|
|
||
|
02:32:09.000 --> 02:32:11.000
|
||
|
what I'm talking about
|
||
|
|
||
|
02:32:11.000 --> 02:32:13.000
|
||
|
you can't take these strict definitions
|
||
|
|
||
|
02:32:13.000 --> 02:32:15.000
|
||
|
with strict meanings and strict
|
||
|
|
||
|
02:32:15.000 --> 02:32:17.000
|
||
|
strict conceptual meaning
|
||
|
|
||
|
02:32:17.000 --> 02:32:19.000
|
||
|
and then apply them to something as limited
|
||
|
|
||
|
02:32:19.000 --> 02:32:21.000
|
||
|
and lame
|
||
|
|
||
|
02:32:21.000 --> 02:32:23.000
|
||
|
as an RNA or DNA virus
|
||
|
|
||
|
02:32:23.000 --> 02:32:25.000
|
||
|
for which we know their biology
|
||
|
|
||
|
02:32:25.000 --> 02:32:27.000
|
||
|
is greatly limited by their replication
|
||
|
|
||
|
02:32:27.000 --> 02:32:29.000
|
||
|
capacity and their lack of
|
||
|
|
||
|
02:32:29.000 --> 02:32:31.000
|
||
|
all these other attributes that we
|
||
|
|
||
|
02:32:31.000 --> 02:32:33.000
|
||
|
generally associate with
|
||
|
|
||
|
02:32:33.000 --> 02:32:35.000
|
||
|
pattern integrity is called life
|
||
|
|
||
|
02:32:37.000 --> 02:32:39.000
|
||
|
and here you see
|
||
|
|
||
|
02:32:39.000 --> 02:32:41.000
|
||
|
the malfunction of the machine with this
|
||
|
|
||
|
02:32:41.000 --> 02:32:43.000
|
||
|
grinning little clown down here
|
||
|
|
||
|
02:32:43.000 --> 02:32:45.000
|
||
|
who thinks it's funny that there's
|
||
|
|
||
|
02:32:45.000 --> 02:32:47.000
|
||
|
contradictions in the biology that they
|
||
|
|
||
|
02:32:47.000 --> 02:32:49.000
|
||
|
discuss and it's funny that it bothers
|
||
|
|
||
|
02:32:49.000 --> 02:32:51.000
|
||
|
that old man as much as it
|
||
|
|
||
|
02:32:51.000 --> 02:32:53.000
|
||
|
doesn't bother him
|
||
|
|
||
|
02:32:53.000 --> 02:32:55.000
|
||
|
because his little mushy brain
|
||
|
|
||
|
02:32:55.000 --> 02:32:57.000
|
||
|
is capable of juggling these words like
|
||
|
|
||
|
02:32:57.000 --> 02:32:59.000
|
||
|
this these contradictions are normal for
|
||
|
|
||
|
02:32:59.000 --> 02:33:01.000
|
||
|
him
|
||
|
|
||
|
02:33:01.000 --> 02:33:03.000
|
||
|
not normal for this old guy
|
||
|
|
||
|
02:33:03.000 --> 02:33:05.000
|
||
|
maybe this old guy is redeemable
|
||
|
|
||
|
02:33:05.000 --> 02:33:07.000
|
||
|
maybe this guy is going to leave
|
||
|
|
||
|
02:33:07.000 --> 02:33:09.000
|
||
|
to him in a few weeks because he starts
|
||
|
|
||
|
02:33:09.000 --> 02:33:11.000
|
||
|
to become convinced that something's not right
|
||
|
|
||
|
02:33:11.000 --> 02:33:15.000
|
||
|
absolutely
|
||
|
|
||
|
02:33:15.000 --> 02:33:17.000
|
||
|
why can't we be flexible Dickson?
|
||
|
|
||
|
02:33:17.000 --> 02:33:19.000
|
||
|
he was the one who came up with that
|
||
|
|
||
|
02:33:19.000 --> 02:33:21.000
|
||
|
Dickson, I like Dickson
|
||
|
|
||
|
02:33:21.000 --> 02:33:23.000
|
||
|
I think Dickson is my new favorite guy
|
||
|
|
||
|
02:33:23.000 --> 02:33:25.000
|
||
|
on Twiv and then they said
|
||
|
|
||
|
02:33:25.000 --> 02:33:27.000
|
||
|
I looked up the reference
|
||
|
|
||
|
02:33:27.000 --> 02:33:29.000
|
||
|
31 that they use for their guide
|
||
|
|
||
|
02:33:29.000 --> 02:33:31.000
|
||
|
and it's called ecological niche by
|
||
|
|
||
|
02:33:31.000 --> 02:33:33.000
|
||
|
a series of authors the Princeton guide to ecology
|
||
|
|
||
|
02:33:33.000 --> 02:33:35.000
|
||
|
that's their guide
|
||
|
|
||
|
02:33:35.000 --> 02:33:37.000
|
||
|
to say what on issues. I'm sorry
|
||
|
|
||
|
02:33:37.000 --> 02:33:39.000
|
||
|
the original concept of Disha was
|
||
|
|
||
|
02:33:39.000 --> 02:33:41.000
|
||
|
published by G. Evelyn Hutchinson
|
||
|
|
||
|
02:33:41.000 --> 02:33:43.000
|
||
|
and everybody else followed suit
|
||
|
|
||
|
02:33:43.000 --> 02:33:45.000
|
||
|
as they agreed with him but viruses don't
|
||
|
|
||
|
02:33:45.000 --> 02:33:47.000
|
||
|
occur as species right? No they don't
|
||
|
|
||
|
02:33:47.000 --> 02:33:49.000
|
||
|
so the word ecology probably is the wrong word
|
||
|
|
||
|
02:33:49.000 --> 02:33:51.000
|
||
|
no why don't we just change the definition of ecology
|
||
|
|
||
|
02:33:51.000 --> 02:33:53.000
|
||
|
there it is ladies and gentlemen
|
||
|
|
||
|
02:33:53.000 --> 02:33:55.000
|
||
|
there it is
|
||
|
|
||
|
02:33:55.000 --> 02:33:57.000
|
||
|
that's the clip for you for all time
|
||
|
|
||
|
02:33:57.000 --> 02:33:59.000
|
||
|
why don't we just change the definition
|
||
|
|
||
|
02:33:59.000 --> 02:34:01.000
|
||
|
of ecology then
|
||
|
|
||
|
02:34:01.000 --> 02:34:03.000
|
||
|
why don't we just change the
|
||
|
|
||
|
02:34:03.000 --> 02:34:05.000
|
||
|
correlative immunity then
|
||
|
|
||
|
02:34:05.000 --> 02:34:07.000
|
||
|
why don't we just change the definition
|
||
|
|
||
|
02:34:07.000 --> 02:34:09.000
|
||
|
why don't we just stop calling it
|
||
|
|
||
|
02:34:09.000 --> 02:34:11.000
|
||
|
transfection
|
||
|
|
||
|
02:34:13.000 --> 02:34:15.000
|
||
|
if you don't see it for the evil
|
||
|
|
||
|
02:34:15.000 --> 02:34:17.000
|
||
|
that it is that what they are saying right now
|
||
|
|
||
|
02:34:17.000 --> 02:34:19.000
|
||
|
right here is the home run of
|
||
|
|
||
|
02:34:19.000 --> 02:34:21.000
|
||
|
home runs that you need to hear nothing
|
||
|
|
||
|
02:34:21.000 --> 02:34:25.000
|
||
|
else you are being lied to
|
||
|
|
||
|
02:34:25.000 --> 02:34:27.000
|
||
|
by a series of charlatans
|
||
|
|
||
|
02:34:27.000 --> 02:34:29.000
|
||
|
that are misusing the language
|
||
|
|
||
|
02:34:29.000 --> 02:34:33.000
|
||
|
of biology to obfuscate their mythology
|
||
|
|
||
|
02:34:33.000 --> 02:34:37.000
|
||
|
that's what's happening here and Vincent
|
||
|
|
||
|
02:34:37.000 --> 02:34:41.000
|
||
|
Renson Yellow is a striking example of it
|
||
|
|
||
|
02:34:41.000 --> 02:34:43.000
|
||
|
in real time right here right now
|
||
|
|
||
|
02:34:43.000 --> 02:34:45.000
|
||
|
listen carefully
|
||
|
|
||
|
02:34:45.000 --> 02:34:49.000
|
||
|
after Dixon so eloquently explains why
|
||
|
|
||
|
02:34:49.000 --> 02:34:51.000
|
||
|
concepts like ecology and species
|
||
|
|
||
|
02:34:51.000 --> 02:34:53.000
|
||
|
and niche
|
||
|
|
||
|
02:34:53.000 --> 02:34:55.000
|
||
|
do not apply to a phenomenon
|
||
|
|
||
|
02:34:55.000 --> 02:34:57.000
|
||
|
like an RNA or DNA virus
|
||
|
|
||
|
02:34:57.000 --> 02:34:59.000
|
||
|
for which there are 20 plus
|
||
|
|
||
|
02:34:59.000 --> 02:35:01.000
|
||
|
or 100 plus
|
||
|
|
||
|
02:35:01.000 --> 02:35:03.000
|
||
|
or 200 plus
|
||
|
|
||
|
02:35:03.000 --> 02:35:05.000
|
||
|
serotypes that can all occupy
|
||
|
|
||
|
02:35:05.000 --> 02:35:07.000
|
||
|
the same niche at once
|
||
|
|
||
|
02:35:07.000 --> 02:35:09.000
|
||
|
hit in a niche
|
||
|
|
||
|
02:35:09.000 --> 02:35:11.000
|
||
|
what is Vincent Rask Rask Rask
|
||
|
|
||
|
02:35:11.000 --> 02:35:13.000
|
||
|
and Yellow say
|
||
|
|
||
|
02:35:13.000 --> 02:35:15.000
|
||
|
let's just change
|
||
|
|
||
|
02:35:15.000 --> 02:35:17.000
|
||
|
the definition of the word
|
||
|
|
||
|
02:35:17.000 --> 02:35:19.000
|
||
|
guide to say what on issues
|
||
|
|
||
|
02:35:19.000 --> 02:35:21.000
|
||
|
I'm sorry
|
||
|
|
||
|
02:35:21.000 --> 02:35:23.000
|
||
|
the original concept of dish was established
|
||
|
|
||
|
02:35:23.000 --> 02:35:25.000
|
||
|
by Gevlin Hutchinson and everybody else followed suit
|
||
|
|
||
|
02:35:25.000 --> 02:35:27.000
|
||
|
yes but they agreed with him but viruses don't occur
|
||
|
|
||
|
02:35:27.000 --> 02:35:29.000
|
||
|
no they don't know they don't so the word of
|
||
|
|
||
|
02:35:29.000 --> 02:35:33.000
|
||
|
probably is the wrong word no why don't we just change the definition of ecology
|
||
|
|
||
|
02:35:33.000 --> 02:35:37.000
|
||
|
I think you can do that but some people would be very upset if you did that
|
||
|
|
||
|
02:35:37.000 --> 02:35:41.000
|
||
|
there's another interesting point here though if you can have multiple infection
|
||
|
|
||
|
02:35:41.000 --> 02:35:45.000
|
||
|
why would eliminating HPV 1618 L that's a good question to a shift like this
|
||
|
|
||
|
02:35:45.000 --> 02:35:49.000
|
||
|
that's right right if they could all get along fine before exactly we wouldn't
|
||
|
|
||
|
02:35:49.000 --> 02:35:53.000
|
||
|
necessarily I wouldn't expect to see a shift so Alan Dove now has a
|
||
|
|
||
|
02:35:53.000 --> 02:35:57.000
|
||
|
completely different stance on things because his
|
||
|
|
||
|
02:35:57.000 --> 02:35:59.000
|
||
|
understanding of biology
|
||
|
|
||
|
02:35:59.000 --> 02:36:01.000
|
||
|
is so flexible
|
||
|
|
||
|
02:36:01.000 --> 02:36:03.000
|
||
|
I mean
|
||
|
|
||
|
02:36:03.000 --> 02:36:07.000
|
||
|
now he suddenly realizes that wait I mean if
|
||
|
|
||
|
02:36:07.000 --> 02:36:11.000
|
||
|
they're they can all be there at the same time then why don't they cause pressure
|
||
|
|
||
|
02:36:11.000 --> 02:36:15.000
|
||
|
obviously the phenomenon that we saw in this paper is due to
|
||
|
|
||
|
02:36:15.000 --> 02:36:19.000
|
||
|
selective in competition pressure because that's the only way we would see a phenomenon like this
|
||
|
|
||
|
02:36:19.000 --> 02:36:23.000
|
||
|
is exactly what Alan Dove said about 10 minutes ago
|
||
|
|
||
|
02:36:23.000 --> 02:36:25.000
|
||
|
in the video
|
||
|
|
||
|
02:36:25.000 --> 02:36:29.000
|
||
|
not 10 minutes ago on my stream but 10 minutes in the video he said
|
||
|
|
||
|
02:36:29.000 --> 02:36:33.000
|
||
|
that obviously they must be competing and that's why niche is a perfectly
|
||
|
|
||
|
02:36:33.000 --> 02:36:37.000
|
||
|
good use and that's why ecology is the right term and he laughed at Dixon
|
||
|
|
||
|
02:36:37.000 --> 02:36:43.000
|
||
|
now 10 minutes after discussing it and after re-ashing it and after discussing
|
||
|
|
||
|
02:36:43.000 --> 02:36:48.000
|
||
|
the paper a little more and reminding him about recombination and all this other stuff
|
||
|
|
||
|
02:36:48.000 --> 02:36:52.000
|
||
|
he now realizes oh wait maybe there shouldn't be and then why did we see this
|
||
|
|
||
|
02:36:52.000 --> 02:36:54.000
|
||
|
phenomenon wow that's very interesting
|
||
|
|
||
|
02:36:58.000 --> 02:37:02.000
|
||
|
we're not talking about diatoms and photosynthesis here Alan Dove
|
||
|
|
||
|
02:37:02.000 --> 02:37:06.000
|
||
|
we're talking about a multi-billion dollar product being hoisted
|
||
|
|
||
|
02:37:06.000 --> 02:37:10.000
|
||
|
on teenagers for no reason for no biology
|
||
|
|
||
|
02:37:10.000 --> 02:37:14.000
|
||
|
that's based in reality and you're just realizing it now
|
||
|
|
||
|
02:37:14.000 --> 02:37:20.000
|
||
|
live in front of people who are coming to you for informed consent on these things
|
||
|
|
||
|
02:37:22.000 --> 02:37:32.000
|
||
|
that's a failure that's a giant failure that's a gigantic failure
|
||
|
|
||
|
02:37:32.000 --> 02:37:40.000
|
||
|
ladies and gentlemen that's what that is that is a crash and burn failure of this system
|
||
|
|
||
|
02:37:40.000 --> 02:37:46.000
|
||
|
that is controlling us and we are seeing through it in real time
|
||
|
|
||
|
02:37:47.000 --> 02:37:52.000
|
||
|
and we are going to break this wheel in real time
|
||
|
|
||
|
02:37:52.000 --> 02:37:56.000
|
||
|
the way that we're going to break this wheel is by breaking down this plan that they had
|
||
|
|
||
|
02:37:56.000 --> 02:38:02.000
|
||
|
this theater that they had and breaking it down by doing the math that they don't want to do
|
||
|
|
||
|
02:38:02.000 --> 02:38:07.000
|
||
|
they want you to believe that there was a gain of function possibility
|
||
|
|
||
|
02:38:07.000 --> 02:38:11.000
|
||
|
that this whole thing came from the worst case scenario
|
||
|
|
||
|
02:38:11.000 --> 02:38:15.000
|
||
|
that it was a gain of function laboratory bio weapon that was released
|
||
|
|
||
|
02:38:15.000 --> 02:38:19.000
|
||
|
and there's this illusion of consensus that that's the reason why you were
|
||
|
|
||
|
02:38:19.000 --> 02:38:23.000
|
||
|
here not to blame for having been scared into taking the vaccine
|
||
|
|
||
|
02:38:23.000 --> 02:38:27.000
|
||
|
because this was the worst case scenario that they sent it to you
|
||
|
|
||
|
02:38:27.000 --> 02:38:32.000
|
||
|
and this illusion of consensus about a novel virus that killed millions of people
|
||
|
|
||
|
02:38:32.000 --> 02:38:35.000
|
||
|
that we saved millions of people from that was likely gain of function
|
||
|
|
||
|
02:38:35.000 --> 02:38:39.000
|
||
|
and that will come again this illusion of consensus is how they got us
|
||
|
|
||
|
02:38:39.000 --> 02:38:43.000
|
||
|
and the way that they sustain this illusion of consensus is by telling you
|
||
|
|
||
|
02:38:43.000 --> 02:38:48.000
|
||
|
the lie that everybody that died in excess in the last three years
|
||
|
|
||
|
02:38:48.000 --> 02:38:52.000
|
||
|
is a result of the mystery virus and the only way this lie works
|
||
|
|
||
|
02:38:52.000 --> 02:38:55.000
|
||
|
is if you don't talk about the do not resuscitate orders
|
||
|
|
||
|
02:38:55.000 --> 02:38:57.000
|
||
|
you don't talk about ventilators
|
||
|
|
||
|
02:38:57.000 --> 02:39:00.000
|
||
|
you don't talk about the lack of use of antibiotics
|
||
|
|
||
|
02:39:00.000 --> 02:39:02.000
|
||
|
you don't talk about the poor use of steroids
|
||
|
|
||
|
02:39:02.000 --> 02:39:04.000
|
||
|
you don't talk about remdesivir or medazlin
|
||
|
|
||
|
02:39:04.000 --> 02:39:07.000
|
||
|
you don't talk about the extra opioid deaths
|
||
|
|
||
|
02:39:07.000 --> 02:39:09.000
|
||
|
you don't talk about death certificate fraud
|
||
|
|
||
|
02:39:09.000 --> 02:39:11.000
|
||
|
you don't talk about all of this math
|
||
|
|
||
|
02:39:11.000 --> 02:39:15.000
|
||
|
about PCR fraud and lateral flow test fraud in the UK
|
||
|
|
||
|
02:39:15.000 --> 02:39:19.000
|
||
|
you don't talk about all of the illusion of virology
|
||
|
|
||
|
02:39:19.000 --> 02:39:26.000
|
||
|
you don't talk about all of the illusion of correlates of immunity
|
||
|
|
||
|
02:39:26.000 --> 02:39:29.000
|
||
|
and you just talk about a novel virus
|
||
|
|
||
|
02:39:29.000 --> 02:39:33.000
|
||
|
you just talk about the millions of people that were killed by the novel virus
|
||
|
|
||
|
02:39:33.000 --> 02:39:37.000
|
||
|
you just talk about gain of function and bioterrorism
|
||
|
|
||
|
02:39:37.000 --> 02:39:39.000
|
||
|
you just talk about how they're going to do it again
|
||
|
|
||
|
02:39:43.000 --> 02:39:45.000
|
||
|
that's how this was done
|
||
|
|
||
|
02:39:45.000 --> 02:39:49.000
|
||
|
you don't need a bioweapon to do this
|
||
|
|
||
|
02:39:49.000 --> 02:39:53.000
|
||
|
you need a spectacular commitment to this lie
|
||
|
|
||
|
02:39:53.000 --> 02:39:59.000
|
||
|
a spectacular commitment by these people to this lie
|
||
|
|
||
|
02:39:59.000 --> 02:40:02.000
|
||
|
is the illusion of consensus that has changed the way we think
|
||
|
|
||
|
02:40:02.000 --> 02:40:04.000
|
||
|
and trapped us in this illusion
|
||
|
|
||
|
02:40:04.000 --> 02:40:10.000
|
||
|
this scooby-doo mystery about trying to figure out whether it was a laboratory leak or a bat cave zoonosis
|
||
|
|
||
|
02:40:10.000 --> 02:40:14.000
|
||
|
that's what this faith is
|
||
|
|
||
|
02:40:14.000 --> 02:40:18.000
|
||
|
and figuring it out and finding the liars and blaming ego health alliances
|
||
|
|
||
|
02:40:18.000 --> 02:40:21.000
|
||
|
is all part of this mystery-solving game
|
||
|
|
||
|
02:40:21.000 --> 02:40:25.000
|
||
|
to brainwash yourself into believing this illusion of consensus
|
||
|
|
||
|
02:40:25.000 --> 02:40:29.000
|
||
|
and the way to break this illusion of consensus is to realize
|
||
|
|
||
|
02:40:29.000 --> 02:40:33.000
|
||
|
that the laboratory leak, the solving of it, was a mystery
|
||
|
|
||
|
02:40:33.000 --> 02:40:35.000
|
||
|
the use had to solve
|
||
|
|
||
|
02:40:35.000 --> 02:40:37.000
|
||
|
that allowed them to do all these things
|
||
|
|
||
|
02:40:37.000 --> 02:40:41.000
|
||
|
under the guise of trying to do their best to solve this novel problem
|
||
|
|
||
|
02:40:41.000 --> 02:40:43.000
|
||
|
that was never novel
|
||
|
|
||
|
02:40:43.000 --> 02:40:47.000
|
||
|
and the illusion of consensus created by these people
|
||
|
|
||
|
02:40:47.000 --> 02:40:50.000
|
||
|
is what brainwashed your family and friends
|
||
|
|
||
|
02:40:50.000 --> 02:40:52.000
|
||
|
it brainwashed the people on TV
|
||
|
|
||
|
02:40:52.000 --> 02:40:54.000
|
||
|
into believing this illusion of consensus
|
||
|
|
||
|
02:40:54.000 --> 02:40:56.000
|
||
|
and it is a faith
|
||
|
|
||
|
02:40:56.000 --> 02:40:58.000
|
||
|
a novel virus
|
||
|
|
||
|
02:40:58.000 --> 02:40:59.000
|
||
|
that's what it is
|
||
|
|
||
|
02:40:59.000 --> 02:41:01.000
|
||
|
call it for what it is
|
||
|
|
||
|
02:41:01.000 --> 02:41:03.000
|
||
|
and the way that the faith isn't a lie
|
||
|
|
||
|
02:41:03.000 --> 02:41:05.000
|
||
|
and it is very different
|
||
|
|
||
|
02:41:05.000 --> 02:41:07.000
|
||
|
than saying that there are no viruses
|
||
|
|
||
|
02:41:07.000 --> 02:41:10.520
|
||
|
if you say that there was an endemic background that they conflated
|
||
|
|
||
|
02:41:10.520 --> 02:41:13.000
|
||
|
it is very different if you say the protocols are murder.
|
||
|
|
||
|
02:41:13.000 --> 02:41:15.000
|
||
|
and a transfection is not medicine
|
||
|
|
||
|
02:41:15.000 --> 02:41:17.000
|
||
|
and they conflated a background signal
|
||
|
|
||
|
02:41:17.000 --> 02:41:19.000
|
||
|
it is very different if you murder
|
||
|
|
||
|
02:41:19.000 --> 02:41:28.000
|
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and a
|
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02:41:28.000 --> 02:41:35.000
|
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|
is in medicine, it's a bioweapon and protocols are murder. But you're not going to survive
|
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|
02:41:35.000 --> 02:41:39.120
|
||
|
and you're not going to escape if you just say that there are no viruses and that they're
|
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02:41:39.120 --> 02:41:45.080
|
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|
lying about everything because they're not. There has to be some truth to the biology
|
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|
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|
02:41:45.080 --> 02:41:51.560
|
||
|
or biologists wouldn't have been fooled. But the truth has to be really, really clever
|
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|
02:41:51.560 --> 02:41:58.240
|
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|
lies. And that's what it is. It's infectious clones. The faith is a lie. There was a
|
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02:41:58.240 --> 02:42:04.120
|
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|
background signal and there remains a background signal that can be conflated as a pandemic.
|
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02:42:04.120 --> 02:42:10.480
|
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|
And if they had to release something or spray something or induce a signal, then the way
|
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|
02:42:10.480 --> 02:42:14.760
|
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|
they would have done it will most likely and most easily is with infectious clones or even
|
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|
|
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|
02:42:14.760 --> 02:42:22.040
|
||
|
transfection of the spike alone. But the faith in the novel virus is being sustained
|
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|
|
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|
02:42:22.040 --> 02:42:30.720
|
||
|
by all the people that we that we currently call heroes right now. And you can see them
|
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|
|
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|
02:42:30.720 --> 02:42:38.520
|
||
|
sustaining the faith because they don't address PCR fraud anymore. They don't address the
|
||
|
|
||
|
02:42:38.520 --> 02:42:43.960
|
||
|
variant and sequencing fraud anymore. They have never known about the death certificate
|
||
|
|
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|
02:42:43.960 --> 02:42:51.160
|
||
|
fraud. They've never known about the RNA purity and the fact that it can't copy itself
|
||
|
|
||
|
02:42:51.160 --> 02:42:55.720
|
||
|
the way that this story goes. They haven't talked about the problems with protein folding
|
||
|
|
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|
02:42:55.720 --> 02:43:00.680
|
||
|
and our inability to understand it in the implications for transfection. They haven't talked about
|
||
|
|
||
|
02:43:00.680 --> 02:43:05.320
|
||
|
transfection in general and it's inappropriate, mis and healthy humans. And they're not talking
|
||
|
|
||
|
02:43:05.320 --> 02:43:09.000
|
||
|
about natural immunity. They've never talked about immuno 101. They've never tried to
|
||
|
|
||
|
02:43:09.000 --> 02:43:16.360
|
||
|
give you a lecture about immuno 101. Giga ohm biological is the only one. Jonathan Cooey
|
||
|
|
||
|
02:43:16.360 --> 02:43:23.240
|
||
|
is the only biologist in three years that has attempted to teach immunology relative to this
|
||
|
|
||
|
02:43:23.240 --> 02:43:29.560
|
||
|
pandemic and to dispel the myths and the mythology of it using biology. I'm the only one.
|
||
|
|
||
|
02:43:31.160 --> 02:43:35.880
|
||
|
You want me to go down the list of people that hasn't done it that could have? It's long.
|
||
|
|
||
|
02:43:36.600 --> 02:43:44.360
|
||
|
Brett Weinstein didn't do it. Chris Martinson didn't do it. Heather Hayne didn't do it.
|
||
|
|
||
|
02:43:47.080 --> 02:43:52.680
|
||
|
Peter McCullough didn't do it. Brian Cole didn't do it. Peter McCory didn't do it.
|
||
|
|
||
|
02:43:53.240 --> 02:43:59.000
|
||
|
Robert Malone didn't do it. Judy Mikovitz hasn't done it.
|
||
|
|
||
|
02:43:59.000 --> 02:44:08.200
|
||
|
I mean, how far do we have to go? How many people do you want me to list? Because it's all of them.
|
||
|
|
||
|
02:44:09.320 --> 02:44:14.600
|
||
|
None of them have taught the biology of natural immunity. None of them have taught
|
||
|
|
||
|
02:44:15.640 --> 02:44:21.000
|
||
|
the extent to which transfection is wholly inappropriate for healthy humans. None of them
|
||
|
|
||
|
02:44:21.640 --> 02:44:28.200
|
||
|
have gone so far as to say that the vaccination schedule in America is a crime except for a very
|
||
|
|
||
|
02:44:28.200 --> 02:44:34.360
|
||
|
few Tess Laurie, Corey Pierre Corey and Peter McCullough.
|
||
|
|
||
|
02:44:38.680 --> 02:44:44.040
|
||
|
It is a very small group of people that is really fighting the fight right now and everybody else
|
||
|
|
||
|
02:44:44.040 --> 02:44:52.200
|
||
|
is faking it. Wittingly or unwittingly. And so you need to share my stream. You need to get this
|
||
|
|
||
|
02:44:52.280 --> 02:44:59.080
|
||
|
in front of all of them so that they can either wake up and apologize and course correct immediately
|
||
|
|
||
|
02:44:59.880 --> 02:45:04.040
|
||
|
or they are put on alert that we actually know who they are.
|
||
|
|
||
|
02:45:07.880 --> 02:45:12.840
|
||
|
Because I'm done playing games with my children's future. This is just starting,
|
||
|
|
||
|
02:45:12.840 --> 02:45:16.360
|
||
|
ladies and gentlemen. My voice is just coming back.
|
||
|
|
||
|
02:45:19.560 --> 02:45:23.720
|
||
|
And I plan to exercise it a lot over the next couple of weeks, three weeks,
|
||
|
|
||
|
02:45:23.720 --> 02:45:30.520
|
||
|
four weeks, five weeks, five months, a year. I ain't stopping until this is stopped. I'm not
|
||
|
|
||
|
02:45:30.520 --> 02:45:36.760
|
||
|
stopping until the elimination of the control group is stopped. I'm not stopping until everyone
|
||
|
|
||
|
02:45:36.760 --> 02:45:41.480
|
||
|
that is capable of understanding these two phrases understands them.
|
||
|
|
||
|
02:45:43.560 --> 02:45:45.160
|
||
|
Until these are common knowledge.
|
||
|
|
||
|
02:45:47.560 --> 02:45:53.720
|
||
|
Until it's common knowledge for a for a for an elementary school teacher to know this biology
|
||
|
|
||
|
02:45:53.720 --> 02:46:00.360
|
||
|
and to teach it. I'm going to be working here again to go biological. As long as CHD will have
|
||
|
|
||
|
02:46:00.360 --> 02:46:09.080
|
||
|
me, I'm going to be working for CHD because I think for the most part, although CHD would like
|
||
|
|
||
|
02:46:09.080 --> 02:46:19.320
|
||
|
to be a big top tent for health freedom. Health freedom is defined by this biology right here.
|
||
|
|
||
|
02:46:20.120 --> 02:46:25.640
|
||
|
That there is no useful way to augment the human immune system through intramuscular injection.
|
||
|
|
||
|
02:46:25.720 --> 02:46:35.480
|
||
|
And this, this criminally negligent bad idea and all of those responsible directly or indirectly
|
||
|
|
||
|
02:46:35.480 --> 02:46:41.960
|
||
|
for petri perpetuating it for the last 20 plus years are criminally negligent liable
|
||
|
|
||
|
02:46:43.640 --> 02:46:50.840
|
||
|
demons. And I'm going to spend the rest of my adult life teaching this biology until it's
|
||
|
|
||
|
02:46:50.840 --> 02:46:59.400
|
||
|
I'm blue in the face or dead. So welcome to the show. Welcome to the big show. That's where we are
|
||
|
|
||
|
02:46:59.400 --> 02:47:08.760
|
||
|
ladies and gentlemen. I believe it's much more likely if it's a lab lead. Stop lying. Stop lying.
|
||
|
|
||
|
02:47:09.720 --> 02:47:14.920
|
||
|
Stop lying. That's where we are ladies and gentlemen. Thanks very much for joining me and I will
|
||
|
|
||
|
02:47:14.920 --> 02:47:31.240
|
||
|
see you again tomorrow night. I hope you're aware and realize that I have no no equalizer here.
|
||
|
|
||
|
02:47:33.480 --> 02:47:39.080
|
||
|
There's no equalizer on my voice right now. This is just a it's a microphone that's actually
|
||
|
|
||
|
02:47:40.040 --> 02:47:44.040
|
||
|
a condenser microphone that's distant right it's supposed to have a direction.
|
||
|
|
||
|
02:47:45.480 --> 02:47:51.720
|
||
|
And so it's just a mic and my voice is really back. It feels stronger than ever. I can finally
|
||
|
|
||
|
02:47:51.720 --> 02:47:56.840
|
||
|
fill the gym during basketball practice and tell the boys what they're doing even when they're
|
||
|
|
||
|
02:47:56.840 --> 02:48:02.040
|
||
|
bouncing the ball. I basically have my old voice back and so I'm really really happy. I'm not
|
||
|
|
||
|
02:48:02.040 --> 02:48:07.480
|
||
|
going to be talking about it a lot anymore. But it was definitely worth taking the two weeks off
|
||
|
|
||
|
02:48:07.560 --> 02:48:14.040
|
||
|
that I did for the recovery of my voice and also just getting everything reoriented for the basketball
|
||
|
|
||
|
02:48:14.040 --> 02:48:18.760
|
||
|
season. And so there's going to be a little flexibility in terms of time but I'm either
|
||
|
|
||
|
02:48:18.760 --> 02:48:23.800
|
||
|
going to be basically going at about four forty five or five o'clock or I'm going to be going at
|
||
|
|
||
|
02:48:23.800 --> 02:48:29.240
|
||
|
about eight or eight thirty or nine o'clock. Just depending on the schedule at home I'm sorry
|
||
|
|
||
|
02:48:29.240 --> 02:48:33.880
|
||
|
but my priority is my family and so I am going to make it a priority to be here on daily but
|
||
|
|
||
|
02:48:34.440 --> 02:48:37.800
|
||
|
the give and take of that is that there's got to be a little flexibility in the
|
||
|
|
||
|
02:48:37.800 --> 02:48:42.520
|
||
|
schedule so you won't be able to always watch it live. But if you look for me every day you'll
|
||
|
|
||
|
02:48:42.520 --> 02:48:49.800
|
||
|
definitely find me. Thanks very much for joining me and I'll see you guys again tomorrow.
|
||
|
|